Standout Papers
Citation Impact
Citing Papers
Partitioning of Lipid-Modified Monomeric GFPs into Membrane Microdomains of Live Cells
2002 StandoutScienceNobel
Insertion of Green Fluorescent Protein into Nonstructural Protein 5A Allows Direct Visualization of Functional Hepatitis C Virus Replication Complexes
2004 StandoutNobel
Imaging Intracellular Fluorescent Proteins at Nanometer Resolution
2006 StandoutScienceNobel
A Photoactivatable GFP for Selective Photolabeling of Proteins and Cells
2002 Science
De novo design of modular and tunable protein biosensors
2021 StandoutNatureNobel
Diffraction-unlimited all-optical imaging and writing with a photochromic GFP
2011 StandoutNatureNobel
Structural basis for activity of highly efficient RNA mimics of green fluorescent protein
2014
Analysis of DsRed Mutants
2002
Photoactivatable fluorescent proteins
2005
Creating new fluorescent probes for cell biology
2002 StandoutNobel
The 2.0-Å Crystal Structure of eqFP611, a Far Red Fluorescent Protein from the Sea Anemone Entacmaea quadricolor
2003
Chaperonin-mediated Folding of Green Fluorescent Protein
1997
A reversibly photoswitchable GFP-like protein with fluorescence excitation decoupled from switching
2011 StandoutNobel
Chapter 6 Enlightening Mitosis: Construction and Expression of Green Fluorescent Fusion Proteins
1998
Combinatorial Marking of Cells and Organelles with Reconstituted Fluorescent Proteins
2004 StandoutNobel
The structural basis for red fluorescence in the tetrameric GFP homolog DsRed.
2000
Optical Probing of Single Fluorescent Molecules and Proteins
2001
Engineering and characterization of a superfolder green fluorescent protein
2005 Standout
Unravelling hepatitis C virus replication from genome to function
2005 StandoutNatureNobel
Circularly permuted variants of the green fluorescent protein
1999
Transient Free Radicals in Iron/Oxygen Reconstitution of Mutant Protein R2 Y122F.
1995
Mapping Interactions between Nuclear Transport Factors in Living Cells Reveals Pathways through the Nuclear Pore Complex
2000
Single photons on demand from a single molecule at room temperature
2000 StandoutNatureNobel
Sensitivity of the yellow variant of green fluorescent protein to halides and nitrate
1999
Di-iron—carboxylate proteins
1995
Imaging and Tracking of Single GFP Molecules in Solution
2000
Generation of Destabilized Green Fluorescent Protein as a Transcription Reporter
1998
Structure and function of the radical enzyme ribonucleotide reductase
2001
Highly Efficient Green Fluorescent Protein-Based Kinase Substrates
1999
Detection in Living Cells of Ca2+-dependent Changes in the Fluorescence Emission of an Indicator Composed of Two Green Fluorescent Protein Variants Linked by a Calmodulin-binding Sequence
1997
A Genetically Encoded Ratiometric Indicator for Chloride
2000
Photoactivation turns green fluorescent protein red
1997
Use of the green fluorescent protein and its mutants in quantitative fluorescence microscopy
1997
De novo design of luciferases using deep learning
2023 StandoutNatureNobel
Quantitative analysis of gene expression with an improved green fluorescent protein
2000
GFP‐like chromoproteins as a source of far‐red fluorescent proteins
2001
Seeing the Wood through the Trees: A Review of Techniques for Distinguishing Green Fluorescent Protein from Endogenous Autofluorescence
2001
One- and Two-Photon Excited Fluorescence Lifetimes and Anisotropy Decays of Green Fluorescent Proteins
2000
Green Fluorescent Protein as a Noninvasive Intracellular pH Indicator
1998
Green fluorescent protein as a scaffold for intracellular presentation of peptides
1998
Visualizing the mechanical activation of Src
2005 StandoutNatureNobel
Simultaneous visualization of multiple protein interactions in living cells using multicolor fluorescence complementation analysis
2003
Crystal structure of reduced protein R2 of ribonucleotide reductase: the structural basis for oxygen activation at a dinuclear iron site
1996
On/off blinking and switching behaviour of single molecules of green fluorescent protein
1997 StandoutNatureNobel
Membrane protein sequestering by ionic protein–lipid interactions
2011 StandoutNatureNobel
Reducing the Environmental Sensitivity of Yellow Fluorescent Protein
2001 StandoutNobel
Excited state reactions in fluorescent proteins
2009
Transition in the Temperature-Dependence of GFP Fluorescence: From Proton Wires to Proton Exit
2005
Dual color detection of cyan and yellow derivatives of green fluorescent protein using conventional fluorescence microscopy and 35-mm photography
2000
Structure and dynamics of green fluorescent protein
1997
Mutations that suppress the thermosensitivity of green fluorescent protein
1996
Structure of ribonucleotide reductase protein R1
1994 Nature
Contribution of the intramolecular hydrogen bond to the shift of the pKa value and the oxidation potential of phenols and phenolate anions
2005
Autofluorescent Proteins in Single-Molecule Research: Applications to Live Cell Imaging Microscopy
2001
Fluorescent proteins: maturation, photochemistry and photophysics
2006
Monitoring protein conformations and interactions by fluorescence resonance energy transfer between mutants of green fluorescent protein
2000 StandoutNobel
Three photoconvertible forms of green fluorescent protein identified by spectral hole-burning.
1999
De novo design of a fluorescence-activating β-barrel
2018 StandoutNatureNobel
Chromophore Environment Provides Clue to “Kindling Fluorescent Protein” Riddle
2003
Natural Animal Coloration Can Be Determined by a Nonfluorescent Green Fluorescent Protein Homolog
2000
Novel fluorescent protein from Discosoma coral and its mutants possesses a unique far‐red fluorescence
2000
Design of generic biosensors based on green fluorescent proteins with allosteric sites by directed evolution
1999
Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus
2001 Standout
A β-Arrestin/Green Fluorescent Protein Biosensor for Detecting G Protein-coupled Receptor Activation
1997
The color of mice: in the light of GFP-variant reporters
2000
Visualization of Interactions among bZIP and Rel Family Proteins in Living Cells Using Bimolecular Fluorescence Complementation
2002
A Genetically Targetable Fluorescent Probe of Channel Gating with Rapid Kinetics
2002
The β2-adrenergic receptor interacts with the Na+/H+-exchanger regulatory factor to control Na+/H+ exchange
1998 StandoutNatureNobel
The Rough Energy Landscape of Superfolder GFP Is Linked to the Chromophore
2007
Evidence by Site-Directed Mutagenesis Supports Long-Range Electron Transfer in Mouse Ribonucleotide Reductase
1995
Mechanism and Cellular Applications of a Green Fluorescent Protein-based Halide Sensor
2000
The evolution of ribonucleotide reduction
1997
Kindling fluorescent proteins for precise in vivo photolabeling
2003
Determination of tumor necrosis factor receptor-associated factor trimerization in living cells by CFP->YFP->mRFP FRET detected by flow cytometry
2005
A Genetically Encoded Optical Probe of Membrane Voltage
1997
Crystal Structures of the Luciferase and Green Fluorescent Protein from Renilla reniformis
2007
Fluorescent proteins from nonbioluminescent Anthozoa species
1999
Photobleaching recovery and anisotropy decay of green fluorescent protein GFP-S65T in solution and cells: cytoplasmic viscosity probed by green fluorescent protein translational and rotational diffusion
1997
Receptor-mediated Targeting of Fluorescent Probes in Living Cells
1999
Crystallographic and energetic analysis of binding of selected anions to the yellow variants of green fluorescent protein 1 1Edited by D. C. Rees
2000
Visualizing secretion and synaptic transmission with pH-sensitive green fluorescent proteins
1998 StandoutNatureNobel
Mice cloned from olfactory sensory neurons
2004 StandoutNatureNobel
Shedding light on disulfide bond formation: engineering a redox switch in green fluorescent protein
2001
Investigating Mitochondrial Redox Potential with Redox-sensitive Green Fluorescent Protein Indicators
2004 StandoutNobel
Insulin disrupts β-adrenergic signalling to protein kinase A in adipocytes
2005 StandoutNatureNobel
Photobleaching GFP reveals protein dynamics inside live cells
1999
Fluorescent indicators for Ca2+based on green fluorescent proteins and calmodulin
1997 StandoutNatureNobel
Family of the green fluorescent protein: Journey to the end of the rainbow
2002
The molecular structure of green fluorescent protein
1996
Directed evolution of green fluorescent protein by a new versatile PCR strategy for site-directed and semi-random mutagenesis
2000
Light-Induced Flickering of DsRed Provides Evidence for Distinct and Interconvertible Fluorescent States
2001
Structural basis of spectral shifts in the yellow-emission variants of green fluorescent protein
1998
Characterization and Use of Green Fluorescent Proteins from Renilla mulleri and Ptilosarcus guernyi for the Human Cell Display of Functional Peptides
2001
Photoswitchable cyan fluorescent protein for protein tracking
2004
Semi‐rational engineering of a coral fluorescent protein into an efficient highlighter
2005
Radical Initiation in the Class I Ribonucleotide Reductase: Long-Range Proton-Coupled Electron Transfer?
2003
"Fluorescent Timer": Protein That Changes Color with Time
2000 Science
Trafficking, Assembly, and Function of a Connexin43-Green Fluorescent Protein Chimera in Live Mammalian Cells
1999
Removal of a cryptic intron and subcellular localization of green fluorescent protein are required to mark transgenic Arabidopsis plants brightly
1997
Geometric and Electronic Structure/Function Correlations in Non-Heme Iron Enzymes
1999 Standout
Circular permutation and receptor insertion within green fluorescent proteins
1999 StandoutNobel
Far-Field Optical Nanoscopy
2007 StandoutScienceNobel
High resolution, fluorescence deconvolution microscopy and tagging with the autofluorescent tracers CFP, GFP, and YFP to study the structural composition of gap junctions in living cells
2001
Ultrafast Excited-State Dynamics in the Green Fluorescent Protein Variant S65T/H148D. 1. Mutagenesis and Structural Studies,
2007
The Role of Dark States in the Photodynamics of the Green Fluorescent Protein Examined with Two-Color Fluorescence Excitation Spectroscopy
2000
Cloning, sequencing, and expression of the adenosylcobalamin-dependent ribonucleotide reductase from Lactobacillus leichmannii.
1993
Dioxygen Activation by Enzymes Containing Binuclear Non-Heme Iron Clusters
1996
THE GREEN FLUORESCENT PROTEIN
1998 StandoutNobel
Shedding light on the dark and weakly fluorescent states of green fluorescent proteins
1999
β-Arrestin-Dependent Formation of β 2 Adrenergic Receptor-Src Protein Kinase Complexes
1999 StandoutScienceNobel
Stable Low-Temperature Photoproducts and Hole Burning of Green Fluorescent Protein (GFP)
1999
Genetically Encoded Fluorescent Biosensors Illuminate the Spatiotemporal Regulation of Signaling Networks
2018
Circularly permuted green fluorescent proteins engineered to sense Ca 2+
2001
Fluorescence correlation spectroscopy reveals fast optical excitation-driven intramolecular dynamics of yellow fluorescent proteins
2000 StandoutNobel
Proton Relay Reaction in Green Fluorescent Protein (GFP): Polarization-Resolved Ultrafast Vibrational Spectroscopy of Isotopically Edited GFP
2006
Crystal Structures of Two Self-Hydroxylating Ribonucleotide Reductase Protein R2 Mutants: Structural Basis for the Oxygen-Insertion Step of Hydroxylation Reactions Catalyzed by Diiron Proteins,
1998
Protonation effects on the chromophore of green fluorescent protein. Quantum chemical study of the absorption spectrum
1997
Connexin-specific distribution within gap junctions revealed in living cells
2000
Fluorescence polarization of green fluorescence protein
2002 StandoutNobel
Development and Use of Fluorescent Protein Markers in Living Cells
2003 Science
Dynamics of fluorescence fluctuations in green fluorescent protein observed by fluorescence correlation spectroscopy
1998
Reconsideration of X, the Diiron Intermediate Formed during Cofactor Assembly in E. coli Ribonucleotide Reductase
1996
Cell Surface Engineering by a Modified Staudinger Reaction
2000 StandoutScienceNobel
Protein Mobility in the Cytoplasm of Escherichia coli
1999
β-Arrestin 2: A Receptor-Regulated MAPK Scaffold for the Activation of JNK3
2000 StandoutScienceNobel
Electron Injection through a Specific Pathway Determines the Outcome of Oxygen Activation at the Diiron Cluster in the F208Y Mutant of Escherichia coli Ribonucleotide Reductase Protein R2
1998
Multicolor and Electron Microscopic Imaging of Connexin Trafficking
2002 StandoutScienceNobel
A new reporter cell line to monitor HIV infection and drug susceptibilityin vitro
1997
A Fluorescent Indicator for Detecting Protein−Protein Interactions in Vivo Based on Protein Splicing
2000
Fluorescence bleaching reveals asymmetric compartment formation prior to cell division in Caulobacter
2003 StandoutNobel
Quantum chemical modeling of structure and absorption spectra of the chromophore in green fluorescent proteins
1998
An Alternate Proton Acceptor for Excited-State Proton Transfer in Green Fluorescent Protein: Rewiring GFP
2008
Theoretical study of the mechanism of peptide ring formation in green fluorescent protein
2000
Illuminating Single Molecules in Condensed Matter
1999 StandoutScienceNobel
Understanding GFP Chromophore Biosynthesis: Controlling Backbone Cyclization and Modifying Post-translational Chemistry,
2005
Red-shifted mutants of green fluorescent protein: reversible photoconversions studied by hole-burning and high-resolution spectroscopy
2002
Photophysics and optical switching in green fluorescent protein mutants
2000
Time-resolved spectroscopy of wild-type and mutant Green Fluorescent Proteins reveals excited state deprotonation consistent with fluorophore-protein interactions
1996
Single Amino Acid Replacement Makes Aequorea victoria Fluorescent Proteins Reversibly Photoswitchable
2009
《〈新编英语教程〉学习指南》部分译文评析
2001
Measurement of cytosolic, mitochondrial, and Golgi pH in single living cells with green fluorescent proteins
1998 StandoutNobel
Collective effects in individual oligomers of the red fluorescent coral protein DsRed
2001
Ultrafast Excited-State Dynamics in the Green Fluorescent Protein Variant S65T/H148D. 2. Unusual Photophysical Properties
2007
Mutational Analysis of Hepatitis C Virus Nonstructural Protein 5A: Potential Role of Differential Phosphorylation in RNA Replication and Identification of a Genetically Flexible Domain
2005
Structure and rotation barriers for ground and excited states of the isolated chromophore of the green fluorescent protein
1998
Structure and mechanism of the reversible photoswitch of a fluorescent protein
2005 StandoutNobel
Sticky Caveats in an Otherwise Glowing Report: Oligomerizing Fluorescent Proteins and Their Use in Cell Biology
2002
Alteration of Stimulus-Specific Guard Cell Calcium Oscillations and Stomatal Closing in Arabidopsis det3 Mutant
2000 StandoutScienceNobel
The Fluorescent Toolbox for Assessing Protein Location and Function
2006 StandoutScienceNobel
Green Fluorescent Protein (GFP): Applications, Structure, and Related Photophysical Behavior
2002
Design of a hyperstable 60-subunit protein icosahedron
2016 StandoutNatureNobel
Optical methods for exploring dynamics of single copies of green fluorescent protein
1999 StandoutNobel
Diversity and evolution of the green fluorescent protein family
2002
Protein Radicals in Enzyme Catalysis
1998 Standout
Real-time light-driven dynamics of the fluorescence emission in single green fluorescent protein molecules
2000
Single-molecule optical spectroscopy of autofluorescent proteins
2002 StandoutNobel
Mechanism of the redox reaction of the Aequorea green fluorescent protein (GFP)
1997
Refined crystal structure of DsRed, a red fluorescent protein from coral, at 2.0-Å resolution
2001
Crystal Structure and Resonance Raman Studies of Protocatechuate 3,4- Dioxygenase Complexed with 3,4-Dihydroxyphenylacetate,
1997
Tryptophan radicals formed by iron/oxygen reaction with Escherichia coli ribonucleotide reductase protein R2 mutant Y122F.
1994
Potential Energy Landscape of the Photoinduced Multiple Proton-Transfer Process in the Green Fluorescent Protein: Classical Molecular Dynamics and Multiconfigurational Electronic Structure Calculations
2006
Specific Covalent Labeling of Recombinant Protein Molecules Inside Live Cells
1998 StandoutScienceNobel
Molecular spectroscopy and dynamics of intrinsically fluorescent proteins: Coral red (dsRed) and yellow (Citrine)
2000 StandoutNobel
Dramatic reduction in fluorescence quantum yield in mutants of Green Fluorescent Protein due to fast internal conversion
1998
O2 Activation by Non-Heme Diiron Proteins: Identification of a Symmetric μ-1,2-Peroxide in a Mutant of Ribonucleotide Reductase
1998
Two-color fluorescence correlation spectroscopy of one chromophore: Application to the E222Q mutant of the green fluorescent protein
2001
Internal Dynamics of Green Fluorescent Protein
1999
Dynamic and quantitative Ca 2+ measurements using improved cameleons
1999 StandoutNobel
Proton-Coupled Electron Transfer
2012 Standout
Structural basis for reversible photobleaching of a green fluorescent protein homologue
2007
From RNA to DNA, Why So Many Ribonucleotide Reductases?
1993 Science
Works of Mats Ormö being referenced
Residues Important for Radical Stability in Ribonucleotide Reductase from Escherichia coli
1995
The Cys292→Ala Substitution in Protein R1 of Class I Ribonucleotide Reductase from Escherichia Coli has a Global Effect on Nucleotide Binding at the Specificity‐Determining Allosteric Site
1996
An ultrafiltration assay for nucleotide binding to ribonucleotide reductase
1990
Structural basis for dual excitation and photoisomerization of the Aequorea victoria green fluorescent protein
1997 StandoutNobel
Autocatalytic generation of Dopa in the engineered protein R2 F208Y from Escherichia coli ribonucleotide reductase and crystal structure of the Dopa-208 protein
1993
Crystal Structure of the Aequorea victoria Green Fluorescent Protein
1996 StandoutScienceNobel
Engineering of the iron site in ribonucleotide reductase to a self-hydroxylating monooxygenase.
1992
Evidence for Two Different Classes of Redox-active Cysteines in Ribonucleotide Reductase of Escherichia coli
1989
The conserved serine 211 is essential for reduction of the dinuclear iron center in protein R2 of Escherichia coli ribonucleotide reductase.
1994