Standout Papers
Citation Impact
Citing Papers
Requirement of Prorenin Receptor and Vacuolar H + -ATPase–Mediated Acidification for Wnt Signaling
2010 Science
Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels
2010 StandoutScienceNobel
The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins
2019 StandoutNobel
Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation
2013 StandoutScience
Lrp6 is required for convergent extension during Xenopus gastrulation
2007
Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness
2017 Standout
G Protein-coupled Receptor Kinases Phosphorylate LRP6 in the Wnt Pathway
2009 StandoutNobel
Membrane stiffening by STOML3 facilitates mechanosensation in sensory neurons
2015
Epidermal Merkel cells are mechanosensory cells that tune mammalian touch receptors
2014 StandoutNatureNobel
Proximal events in Wnt signal transduction
2009
Ciliary proteins link basal body polarization to planar cell polarity regulation
2007
Loss of Fat4 disrupts PCP signaling and oriented cell division and leads to cystic kidney disease
2008
Abiotic Stress Signaling and Responses in Plants
2016 Standout
The Mechanosensitive Ion Channel Piezo Inhibits Axon Regeneration
2019 StandoutNobel
Discoveries in structure and physiology of mechanically activated ion channels
2020 StandoutNatureNobel
MEC-2 Is Recruited to the Putative Mechanosensory Complex in C. elegans Touch Receptor Neurons through Its Stomatin-like Domain
2004 StandoutNobel
A Molecular Profile of Focal Segmental Glomerulosclerosis from Formalin-Fixed, Paraffin-Embedded Tissue
2010
Dishevelled: The hub of Wnt signaling
2009
Transcriptional induction of slit diaphragm genes by Lmx1b is required in podocyte differentiation
2002
Podocyte-Associated Molecules in Puromycin Aminonucleoside Nephrosis of the Rat
2002
The complex world of WNT receptor signalling
2012
The nonmotile ciliopathies
2009
Dishevelled Promotes Wnt Receptor Degradation through Recruitment of ZNRF3/RNF43 E3 Ubiquitin Ligases
2015
Determinants of Vascular Permeability in the Kidney Glomerulus
2002
Kif3a constrains β-catenin-dependent Wnt signalling through dual ciliary and non-ciliary mechanisms
2007
Secreted and Transmembrane Wnt Inhibitors and Activators
2012
Piezo proteins are pore-forming subunits of mechanically activated channels
2012 StandoutNatureNobel
The primary cilium as a cellular signaling center: lessons from disease
2009
Advances in the pathogenesis and treatment of polycystic kidney disease
2009
Wnt5a functions in planar cell polarity regulation in mice
2007
Plasma Membrane Targeting of Podocin Through the Classical Exocytic Pathway: Effect of NPHS2 Mutations
2003
The KLHL12–Cullin-3 ubiquitin ligase negatively regulates the Wnt–β-catenin pathway by targeting Dishevelled for degradation
2006
Effects of extracellular matrix viscoelasticity on cellular behaviour
2020 StandoutNature
Tuning Piezo ion channels to detect molecular-scale movements relevant for fine touch
2014
Extracellular Proteins Organize the Mechanosensory Channel Complex in C. elegans Touch Receptor Neurons
2004 StandoutNobel
Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice
2010
Primary Cilia Are Not Required for Normal Canonical Wnt Signaling in the Mouse Embryo
2009
Autophagy: Renovation of Cells and Tissues
2011 Standout
ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner
2012 Nature
Mechanically Activated Ion Channels
2015 StandoutNobel
The Role of Frizzled3 and Frizzled6 in Neural Tube Closure and in the Planar Polarity of Inner-Ear Sensory Hair Cells
2006
The Vertebrate Primary Cilium in Development, Homeostasis, and Disease
2009
Ephrin-B2 regulates VEGFR2 function in developmental and tumour angiogenesis
2010 Nature
Ubiquitin-dependent regulation of COPII coat size and function
2012 StandoutNatureNobel
Linking actin dynamics and gene transcription to drive cellular motile functions
2010
Conformational changes in the G protein Gs induced by the β2 adrenergic receptor
2011 StandoutNatureNobel
The force-from-lipid (FFL) principle of mechanosensitivity, at large and in elements
2014
Wnt/β-Catenin Signaling and Disease
2012 Standout
Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases
2009 Standout
Mechanism of Intracellular cAMP Sensor Epac2 Activation
2011
Defective Trafficking of Nephrin Missense Mutants Rescued by a Chemical Chaperone
2004
Piezo2 is the major transducer of mechanical forces for touch sensation in mice
2014 StandoutNatureNobel
Dual and opposing roles of primary cilia in medulloblastoma development
2009
Generating Cellular Diversity and Spatial Form: Wnt Signaling and the Evolution of Multicellular Animals
2016
The ciliary flow sensor and polycystic kidney disease
2013
Dishevelled controls apical docking and planar polarization of basal bodies in ciliated epithelial cells
2008
Systematic Mapping of WNT-FZD Protein Interactions Reveals Functional Selectivity by Distinct WNT-FZD Pairs
2015
Frizzled/PCP signalling: a conserved mechanism regulating cell polarity and directed motility
2007
M-Type Phospholipase A 2 Receptor as Target Antigen in Idiopathic Membranous Nephropathy
2009 Standout
Experimental membranous nephropathy redux
2005
Cellular and Molecular Mechanisms of Pain
2009 StandoutNobel
Cancer immunotherapy comes of age
2011 StandoutNature
Mammalian Kidney Development: Principles, Progress, and Projections
2012
Wnt/β-Catenin Signaling in Development and Disease
2006 Standout
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
2020 StandoutNobel
Touch sensitivity in Caenorhabditis elegans
2007 StandoutNobel
Disruption of E-Cadherin-Mediated Adhesion Induces a Functionally Distinct Pathway of Dendritic Cell Maturation
2007
The Glomerular Transcriptome and a Predicted Protein–Protein Interaction Network
2007
Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling
2017 StandoutNatureNobel
Basic and Therapeutic Aspects of Angiogenesis
2011 Standout
Ciliar functions in the nephron
2009
The planar cell polarity effector Fuz is essential for targeted membrane trafficking, ciliogenesis and mouse embryonic development
2009
Ciliogenesis defects in embryos lacking inturned or fuzzy function are associated with failure of planar cell polarity and Hedgehog signaling
2006
Defective planar cell polarity in polycystic kidney disease
2005
Sensors and regulators of intracellular pH
2009 Standout
Impaired Wnt–β-catenin signaling disrupts adult renal homeostasis and leads to cystic kidney ciliopathy
2009
S-Palmitoylation and Ubiquitination Differentially Regulate Interferon-induced Transmembrane Protein 3 (IFITM3)-mediated Resistance to Influenza Virus
2012
The role of Drosophila Piezo in mechanical nociception
2012 StandoutNatureNobel
PCP effector gene Inturned is an important regulator of cilia formation and embryonic development in mammals
2010
COPII and the regulation of protein sorting in mammals
2011 StandoutNobel
Endothelial development taking shape
2011
Pericytes regulate the blood–brain barrier
2010 StandoutNature
TRP channels and mechanosensory transduction: insights into the arterial myogenic response
2008
Genetically encoded calcium indicator illuminates calcium dynamics in primary cilia
2013
Expression of podocalyxin enhances the adherence, migration, and intercellular communication of cells
2008
Molecular mechanisms and clinical applications of angiogenesis
2011 StandoutNature
VEGF in Signaling and Disease: Beyond Discovery and Development
2019 Standout
Wg and Wnt4 provide long-range directional input to planar cell polarity orientation in Drosophila
2013
Process formation of podocytes: morphogenetic activity of microtubules and regulation by protein serine/threonine phosphatase PP2A
2001
The role of primary cilia in neuronal function
2010
Neurosensory mechanotransduction
2008 StandoutNobel
The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal
2011
The primary cilium: a signalling centre during vertebrate development
2010 Standout
Nociceptors: the sensors of the pain pathway
2010 StandoutNobel
Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities
2017 Standout
Role of YAP/TAZ in mechanotransduction
2011 StandoutNature
Nephrin Dissociates from Actin, and Its Expression Is Reduced in Early Experimental Membranous Nephropathy
2002
Multiple Wnts Redundantly Control Polarity Orientation in Caenorhabditis elegans Epithelial Stem Cells
2011
Loss of Oriented Cell Division Does not Initiate Cyst Formation
2009
Disruption of the basal body compromises proteasomal function and perturbs intracellular Wnt response
2007
The Ciliopathies: An Emerging Class of Human Genetic Disorders
2006
MEC-2 and MEC-6 in the Caenorhabditis elegans Sensory Mechanotransduction Complex: Auxiliary Subunits that Enable Channel Activity
2008
Cell Biology of the Glomerular Podocyte
2003 Standout
Wnt/β-catenin signaling requires interaction of the Dishevelled DEP domain and C terminus with a discontinuous motif in Frizzled
2012
Eukaryotic Mechanosensitive Channels
2010 Nobel
β-Arrestin–Mediated Localization of Smoothened to the Primary Cilium
2008 StandoutScienceNobel
Patched1 Regulates Hedgehog Signaling at the Primary Cilium
2007 StandoutScience
Subunit composition of a DEG/ENaC mechanosensory channel of Caenorhabditis elegans
2015 Nobel
Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosis
2015 StandoutNobel
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Interleukin-4 and -13 promote basolateral secretion of H+and cathepsin L by glomerular epithelial cells
2002
The Primary Cilium as the Cell's Antenna: Signaling at a Sensory Organelle
2006 Science
Organogenesis in a dish: Modeling development and disease using organoid technologies
2014 StandoutScience
Transcriptional induction of slit diaphragm genes by Lmx1b is required in podocyte differentiation
2002
Towards an integrated view of Wnt signaling in development
2009
Comprehensive Description of the N-Glycoproteome of Mouse Pancreatic β-Cells and Human Islets
2011
Interferon-Stimulated Genes: A Complex Web of Host Defenses
2014 StandoutNobel
Piezo1, a mechanically activated ion channel, is required for vascular development in mice
2014 StandoutNobel
Overview of Structure and Function of Mammalian Cilia
2006
Adapting Proteostasis for Disease Intervention
2008 StandoutScience
Control of stem cell self-renewal and differentiation by the heterochronic genes and the cellular asymmetry machinery in Caenorhabditis elegans
2015 StandoutNobel
Rab10 associates with primary cilia and the exocyst complex in renal epithelial cells
2010
Tissue/planar cell polarity in vertebrates: new insights and new questions
2007
Polycystins and Primary Cilia: Primers for Cell Cycle Progression
2009
Caught flat-footed: podocyte damage and the molecular bases of focal glomerulosclerosis
2001
The developmental biology of Dishevelled: an enigmatic protein governing cell fate and cell polarity
2005
Podocyte slit-diaphragm protein nephrin is linked to the actin cytoskeleton
2002
Satellite Cells and the Muscle Stem Cell Niche
2013 Standout
Stiffened lipid platforms at molecular force foci
2013
Amino acid transport in podocytes
2000
Deletion of IFT20 in the mouse kidney causes misorientation of the mitotic spindle and cystic kidney disease
2008
Polycystic Kidney Disease
2008
Chemical Glycoproteomics
2016 StandoutNobel
Works of Matias Simons being referenced
Scribble participates in Hippo signaling and is required for normal zebrafish pronephros development
2009
Podocin and MEC-2 bind cholesterol to regulate the activity of associated ion channels
2006 StandoutNobel
Polycystic kidney disease: Cell division without a c(l)ue?
2006
Involvement of Lipid Rafts in Nephrin Phosphorylation and Organization of the Glomerular Slit Diaphragm
2001
Podocyte polarity signalling
2009
Directed Membrane Transport Is Involved in Process Formation in Cultured Podocytes
1999
Podocin, a raft-associated component of the glomerular slit diaphragm, interacts with CD2AP and nephrin
2001
Electrochemical cues regulate assembly of the Frizzled/Dishevelled complex at the plasma membrane during planar epithelial polarization
2009
Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways
2005
Wnt Signaling in Polycystic Kidney Disease
2007
Regulation of ciliary polarity by the APC/C
2009
Planar Cell Polarity Signaling: From Fly Development to Human Disease
2008
FZD6encoding the Wnt receptor frizzled 6 is mutated in autosomal‐recessive nail dysplasia
2011
Podocin, a raft-associated component of the glomerular slit diaphragm, interacts with CD2AP and nephrin
2001