Citation Impact
Citing Papers
Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7
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Modulation of immune cell reactivity with cis -binding Siglec agonists
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Selective blockade of inhibitory Fcγ receptor enables human dendritic cell maturation with IL-12p70 production and immunity to antibody-coated tumor cells
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Mouse models of acute and chronic hepacivirus infection
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Mature natural killer cells reset their responsiveness when exposed to an altered MHC environment
2010
Mouse NKR-P1B, a Novel NK1.1 Antigen with Inhibitory Function
1999
NKG2D Is Critical for NK Cell Activation in Host Defense against Pseudomonas aeruginosa Respiratory Infection
2008
NK Cell Responsiveness Is Tuned Commensurate with the Number of Inhibitory Receptors for Self-MHC Class I: The Rheostat Model
2009
Inhibitory NK-cell receptors on T cells: witness of the past, actors of the future
2004
LAIR-1, a Novel Inhibitory Receptor Expressed on Human Mononuclear Leukocytes
1997
Association of killer cell immunoglobulin‐like receptors with scleroderma
2004
The activating form of CD94 receptor complex: CD94 covalently associated with the Kp39 protein that represents the product of the NKG2-C gene
1998
Signaling through human killer cell activating receptors triggers tyrosine phosphorylation of an associated protein complex
1998
Regulation of KIR expression in human T cells: a safety mechanism that may impair protective T-cell responses
1998
Immunoreceptor tyrosine-based inhibition motifs
1997
Dual antibody therapy to harness the innate anti-tumor immune response to enhance antibody targeting of tumors
2015
Sequence Analysis of the Ly49 Cluster in C57BL/6 Mice: A Rapidly Evolving Multigene Family in the Immune System
2002
Identification of new populations of chicken natural killer (NK) cells
2010
A forward-genetic approach for analysis of the immune system
2003 StandoutNobel
Combination cancer immunotherapy and new immunomodulatory targets
2015
Combining immunotherapy and targeted therapies in cancer treatment
2012
The trafficking of natural killer cells
2007
Oncogenic kinase signalling
2001 StandoutNature
Natural killer cell–directed therapies: moving from unexpected results to successful strategies
2008
The biology and management of non-small cell lung cancer
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Microbial Flora Drives Interleukin 22 Production in Intestinal NKp46+ Cells that Provide Innate Mucosal Immune Defense
2008
Identification of the mouse killer immunoglobulin-like receptor-like (Kirl) gene family mapping to Chromosome X
2003
Recognition of microorganisms and activation of the immune response
2007 StandoutNature
Co-stimulation in T cell responses
1997 StandoutNobel
Liver-resident NK cells confer adaptive immunity in skin-contact inflammation
2013
Kinetics and peptide dependency of the binding of the inhibitory NK receptor CD94/NKG2-A and the activating receptor CD94/NKG2-C to HLA-E
1999
The CD94 and NKG2‐A C‐type lectins covalently assemble to form a natural killer cell inhibitory receptor for HLA class I molecules
1997
Exacerbated graft-versus-host disease in Pirb−/− mice
2004
Opposing Functions of the T Cell Receptor Kinase ZAP-70 in Immunity and Tolerance Differentially Titrate in Response to Nucleotide Substitutions
2007
Identification and molecular characterization of a natural mutant of the p50.2/KIR2DS2 activating NK receptor that fails to mediate NK cell triggering
2000
Inhibitory Pathways Triggered by ITIM-Containing Receptors
1999
Sepsis-induced immunosuppression: from cellular dysfunctions to immunotherapy
2013 Standout
Immune functions encoded by the natural killer gene complex
2003
SLP-76 Is a Direct Substrate of SHP-1 Recruited to Killer Cell Inhibitory Receptors
1998
Commitment to the Regulatory T Cell Lineage Requires CARMA1 in the Thymus but Not in the Periphery
2009 StandoutNobel
Interleukin-22-producing innate immune cells: new players in mucosal immunity and tissue repair?
2009
DC ablation in mice: promises, pitfalls, and challenges
2007
Natural Killer Cells: From No Receptors to Too Many
1997
Human nutrition, the gut microbiome and the immune system
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Functions of natural killer cells
2008 Standout
Mechanism of Action of Conventional and Targeted Anticancer Therapies: Reinstating Immunosurveillance
2013
Paired immunoglobulin-like receptor B (PIR-B) inhibits BCR-induced activation of Syk and Btk by SHP-1
1999
Nuclear factor-κB in cancer development and progression
2006 StandoutNature
PILRα, a Novel Immunoreceptor Tyrosine-based Inhibitory Motif-bearing Protein, Recruits SHP-1 upon Tyrosine Phosphorylation and Is Paired with the Truncated Counterpart PILRβ
2000
The Application of Natural Killer Cell Immunotherapy for the Treatment of Cancer
2015
Immunoreceptor DAP12 bearing a tyrosine-based activation motif is involved in activating NK cells
1998 Nature
Natural killer cell receptors in the horse: evidence for the existence of multiple transcribed LY49 genes
2004
A loss-of-function RNA interference screen for molecular targets in cancer
2006 Nature
Functional interactions between the gut microbiota and host metabolism
2012 StandoutNature
Killer cell receptors: keeping pace with MHC class I evolution
1997
Inhibition of antigen-induced T cell response and antibody-induced NK cell cytotoxicity by NKG2A: association of NKG2A with SHP-1 and SHP-2 protein-tyrosine phosphatases
1998
Authentic IgM Fc Receptor (FcμR)
2017
Natural killer cell receptors in cattle: a bovine killer cell immunoglobulin‐like receptor multigene family contains members with divergent signaling motifs
2003
A Novel Phosphotyrosine Motif with a Critical Amino Acid at Position −2 for the SH2 Domain-mediated Activation of the Tyrosine Phosphatase SHP-1
1997
Effector and regulatory events during natural killer–dendritic cell interactions
2006
The two NF-κB activation pathways and their role in innate and adaptive immunity
2004 Standout
Two genes in the rat homologous to human NKG2
1998
Identification of the rat homologue of the human NKp46 triggering receptor
1999
HLA class I specific inhibitory receptors
1997
Clinical trials of antibody therapy
2000
Arousal and inhibition of human NK cells
1997
HumanKLRF1, a novel member of the killer cell lectin-like receptor gene family: molecular characterization, genomic structure, physical mapping to the NK gene complex and expression analysis
2000
Combined Natural Killer Cell and Dendritic Cell Functional Deficiency in KARAP/DAP12 Loss-of-Function Mutant Mice
2000
Costimulatory signals mediated by the ITAM motif cooperate with RANKL for bone homeostasis
2004 Nature
CD28 and CTLA‐4 coreceptor expression and signal transduction
2009
Natural Killer (NK) Cells in Antibacterial Innate Immunity: Angels or Devils?
2011
BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1
2003 StandoutNobel
Phenotype and Functions of Natural Killer Cells in Critically-Ill Septic Patients
2012
The LLT1 receptor induces IFN-γ production by human natural killer cells
2003
Identification of Lps2 as a key transducer of MyD88-independent TIR signalling
2003 StandoutNatureNobel
SHP-1 Regulation of p62DOK Tyrosine Phosphorylation in Macrophages
1999
Self-tolerance of natural killer cells
2006
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
2006 StandoutNature
Deletion of SHIP or SHP-1 Reveals Two Distinct Pathways for Inhibitory Signaling
1997
p49, a putative HLA class I-specific inhibitory NK receptor belonging to the immunoglobulin superfamily
1998
gp49B1-αvβ3 interaction inhibits antigen-induced mast cell activation
2001
Association of DAP12 with Activating CD94/NKG2C NK Cell Receptors
1998
Unusual biochemical features and follicular dendritic cell expression of human Fcα/μ receptor
2007
Dendritic cells and the control of immunity
1998 StandoutNatureNobel
Identification of NKp80, a novel triggering molecule expressed by human NK cells
2001
DAP12-Deficient Mice Fail to Develop Autoimmunity Due to Impaired Antigen Priming
2000
Major histocompatibility complex class I‐specific receptors on human natural killer and T lymphocytes
1997
Molecular and functional characterization of IRp60, a member of the immunoglobulin superfamily that functions as an inhibitory receptor in human NK cells
1999
A Novel Protein-Protein Interaction between a G Protein-coupled Receptor and the Phosphatase SHP-2 Is Involved in Bradykinin-induced Inhibition of Cell Proliferation
2002
CARMA1, BCL-10 and MALT1 in lymphocyte development and activation
2004
A Novel Immunoglobulin Superfamily Receptor for Cellular and Viral MHC Class I Molecules
1997
Inferences, questions and possibilities in Toll-like receptor signalling
2004 StandoutNatureNobel
The role of tyrosine phosphorylation and PTP‐1C in CTLA‐4 signal transduction
1996 StandoutNobel
Pathogen Recognition and Innate Immunity
2006 Standout
NKG2D recruits two distinct adapters to trigger NK cell activation and costimulation
2002
Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters
2009 Standout
Natural killer cell trafficking in vivo requires a dedicated sphingosine 1-phosphate receptor
2007
Molecular Cloning of a Novel Murine Cell-surface Glycoprotein Homologous to Killer Cell Inhibitory Receptors
1997
Functional Roles of the IgM Fc Receptor in the Immune System
2019 StandoutNobel
FcγRIIB1 Inhibition of BCR-Mediated Phosphoinositide Hydrolysis and Ca2+ Mobilization Is Integrated by CD19 Dephosphorylation
1997
Cutting Edge: Ly-49D and Ly-49H Associate with Mouse DAP12 and Form Activating Receptors
1998
Tolerance and Alloreactivity of the Ly49D Subset of Murine NK Cells
1999
Positive Recognition of MHC Class I Molecules by the Ly49D Receptor of Murine NK Cells
1999
Minimal requirement for induction of natural cytotoxicity and intersection of activation signals by inhibitory receptors
2009
Manipulation of T cell costimulatory and inhibitory signals for immunotherapy of prostate cancer
1997 StandoutNobel
NK CELL RECOGNITION
2004 Standout
Cytotoxic T lymphocyte antigen-4 (CTLA-4) regulates primary and secondary peptide-specific CD4+T cell responses
1999 StandoutNobel
The Membrane-Proximal Immunoreceptor Tyrosine-Based Inhibitory Motif Is Critical for the Inhibitory Signaling Mediated by Siglecs-7 and -9, CD33-Related Siglecs Expressed on Human Monocytes and NK Cells
2004
Pivotal Role of KARAP/DAP12 Adaptor Molecule in the Natural Killer Cell–mediated Resistance to Murine Cytomegalovirus Infection
2002
The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)
2016 Standout
Differential binding to HLA-C of p50-activating and p58-inhibitory natural killer cell receptors
1998
Multiplicity and plasticity of natural killer cell signaling pathways
2005
NK CELL RECEPTORS
1998 Standout
Maturation of mouse NK cells is a 4-stage developmental program
2009
B7x: A widely expressed B7 family member that inhibits T cell activation
2003 StandoutNobel
NKp44, A Triggering Receptor Involved in Tumor Cell Lysis by Activated Human Natural Killer Cells, Is a Novel Member of the Immunoglobulin Superfamily
1999
Regulation of Inhibitory and Activating Killer-Cell Ig-Like Receptor Expression Occurs in T Cells After Termination of TCR Rearrangements
2001
Nonoverlapping roles of PD-1 and FoxP3 in maintaining immune tolerance in a novel autoimmune pancreatitis mouse model
2016 StandoutNobel
Regulation of the Natural Killer Cell Receptor Repertoire
2001
Interactions Between the Microbiota and the Immune System
2012 StandoutScience
Interaction of CTLA-4 with AP50, a clathrin-coated pit adaptor protein
1997 StandoutNobel
Diabetic nephropathy is markedly enhanced in mice lacking the bradykinin B2 receptor
2004 StandoutNobel
Turning on Natural Killer Cells
2000
Engagement of the Pd-1 Immunoinhibitory Receptor by a Novel B7 Family Member Leads to Negative Regulation of Lymphocyte Activation
2000 StandoutNobel
Impact of β2 integrin deficiency on mouse natural killer cell development and function
2011 StandoutNobel
Toll-like receptor 4 polymorphisms are associated with resistance to Legionnaires' disease
2005 StandoutNobel
Fc RECEPTOR BIOLOGY
1997
Activating Receptors and Coreceptors Involved in Human Natural Killer Cell-Mediated Cytolysis
2001 Standout
Characterization of inhibitory and stimulatory forms of the murine natural killer cell receptor 2B4
1999
Ly-49W, an Activating Receptor of Nonobese Diabetic Mice With Close Homology to the Inhibitory Receptor Ly-49G, Recognizes H-2Dk and H-2Dd
2001
A Common Inhibitory Receptor for Major Histocompatibility Complex Class I Molecules on Human Lymphoid and Myelomonocytic Cells
1997
p46, a Novel Natural Killer Cell–specific Surface Molecule That Mediates Cell Activation
1997
Kinase requirements in human cells: III. Altered kinase requirements inVHL−/− cancer cells detected in a pilot synthetic lethal screen
2008 StandoutNobel
Induction of autoimmune disease by deletion of CTLA-4 in mice in adulthood
2016 StandoutNobel
Structure and Function of Natural Killer Cell Receptors: Multiple Molecular Solutions to Self, Nonself Discrimination
2002
SHP-1- and Phosphotyrosine-Independent Inhibitory Signaling by a Killer Cell Ig-Like Receptor Cytoplasmic Domain in Human NK Cells
2002
Natural Killer Cell Signaling Pathways
2004 Science
Enhancement of Class II-Restricted T cell Responses by Costimulatory NK Receptors for Class I MHC Proteins
1996 Science
Functional expression of CD43 on human natural killer cells
1999
Gntb-A, a Novel Sh2d1a-Associated Surface Molecule Contributing to the Inability of Natural Killer Cells to Kill Epstein-Barr Virus–Infected B Cells in X-Linked Lymphoproliferative Disease
2001
Selective Activation of the c-Jun NH2-terminal Protein Kinase Signaling Pathway by Stimulatory KIR in the Absence of KARAP/DAP12 in CD4+ T Cells
2003
T-Independent Immune Response: New Aspects of B Cell Biology
2000 StandoutScienceNobel
A novel pair of immunoglobulin-like receptors expressed by B cells and myeloid cells
1997
Detection of T cell responses to a ubiquitous cellular protein in autoimmune disease
2014 StandoutScienceNobel
Precision glycocalyx editing as a strategy for cancer immunotherapy
2016 StandoutNobel
PD-1 immunoreceptor inhibits B cell receptor-mediated signaling by recruiting src homology 2-domain-containing tyrosine phosphatase 2 to phosphotyrosine
2001 StandoutNobel
Proenkephalin+regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function
2020 StandoutNobel
Functional Role for Syk Tyrosine Kinase in Natural Killer Cell–mediated Natural Cytotoxicity
1997
Human natural killer cells
2008
Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection
2004 StandoutNobel
Cytotoxic T lymphocyte antigen-4 (CTLA-4) regulates the size, reactivity, and function of a primed pool of CD4+T cells
2000 StandoutNobel
Effectiveness of Donor Natural Killer Cell Alloreactivity in Mismatched Hematopoietic Transplants
2002 StandoutScience
FDF03, a Novel Inhibitory Receptor of the Immunoglobulin Superfamily, Is Expressed by Human Dendritic and Myeloid Cells
2000
Biochemical Nature and Cellular Distribution of the Paired Immunoglobulin-like Receptors, PIR-A and PIR-B
1999
Gain of Virulence Caused by Loss of a Gene in Murine Cytomegalovirus
2004
Association with FcRγ Is Essential for Activation Signal through NKR-P1 (CD161) in Natural Killer (NK) Cells and NK1.1+ T Cells
1997
Identification and Molecular Characterization of Nkp30, a Novel Triggering Receptor Involved in Natural Cytotoxicity Mediated by Human Natural Killer Cells
1999
Killer Cell Inhibitory Receptor Recognition of Human Leukocyte Antigen (HLA) Class I Blocks Formation of a pp36/PLC-γ Signaling Complex in Human Natural Killer (NK) Cells
1996
Interaction of Ly-49D+ NK Cells with H-2Dd Target Cells Leads to Dap-12 Phosphorylation and IFN-γ Secretion
2000
REGULATION OF IMMUNE RESPONSES THROUGH INHIBITORY RECEPTORS
1999
Identification and Molecular Cloning of P75/Airm1, a Novel Member of the Sialoadhesin Family That Functions as an Inhibitory Receptor in Human Natural Killer Cells
1999
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
Spatial Organization of Signal Transduction Molecules in the NK Cell Immune Synapses During MHC Class I-Regulated Noncytolytic and Cytolytic Interactions
2001
Ly-49D and Ly-49H associate with mouse DAP12 and form activating receptors.
1998
Innate or Adaptive Immunity? The Example of Natural Killer Cells
2011 StandoutScience
Immune Inhibitory Receptors
2000 Science
Elicitation of structure-specific antibodies by epitope scaffolds
2010 StandoutNobel
SHP-1 Binds and Negatively Modulates the c-Kit Receptor by Interaction with Tyrosine 569 in the c-Kit Juxtamembrane Domain
1998
Works of Mathieu Bléry being referenced
Anti-KIR antibody enhancement of anti-lymphoma activity of natural killer cells as monotherapy and in combination with anti-CD20 antibodies
2013
Transduction of cytotoxic signals in natural killer cells: a general model of fine tuning between activatory and inhibitory pathways in lymphocytes
1997
Human and mouse killer-cell inhibitory receptors recruit PTP1C and PTP1D protein tyrosine phosphatases.
1996
Reconstituted Killer Cell Inhibitory Receptors for Major Histocompatibility Complex Class I Molecules Control Mast Cell Activation Induced via Immunoreceptor Tyrosine-based Activation Motifs
1997
Inhibition of IgE-mediated mast cell activation by the paired Ig-like receptor PIR-B
2001
The Role of Natural Killer Cells in Sepsis
2011
Function of killer cell inhibitory receptors for MHC class I molecules
1996
Signaling pathways engaged by NK cell receptors: double concerto for activating receptors, inhibitory receptors and NK cells
2000
Identifying the MAGUK Protein Carma-1 as a Central Regulator of Humoral Immune Responses and Atopy by Genome-Wide Mouse Mutagenesis
2003
Gene Structure, Expression Pattern, and Biological Activity of Mouse Killer Cell Activating Receptor-associated Protein (KARAP)/DAP-12
1998
Early signaling via inhibitory and activating NK receptors
2000
Targeting MICA with therapeutic antibodies for the treatment of cancer
2013
Genetic and antibody-mediated reprogramming of natural killer cell missing-self recognition in vivo
2009
Analysis of an Ethylnitrosourea-generated Mouse Mutation Defines a Cell Intrinsic Role of Nuclear Factor κB2 in Regulating Circulating B Cell Numbers
2002
IPH2101, a novel anti-inhibitory KIR antibody, and lenalidomide combine to enhance the natural killer cell versus multiple myeloma effect
2011
Inhibition of IgE-mediated mast cell activation by the paired Ig-like receptor PIR-B
2001
TLR3 and Rig-Like Receptor on Myeloid Dendritic Cells and Rig-Like Receptor on Human NK Cells Are Both Mandatory for Production of IFN-γ in Response to Double-Stranded RNA
2010
Identification, activation, and selectivein vivoablation of mouse NK cells via NKp46
2007
The paired Ig-like receptor PIR-B is an inhibitory receptor that recruits the protein-tyrosine phosphatase SHP-1
1998