Standout Papers
Citation Impact
Citing Papers
Activation of the p62‐Keap1‐NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells
2015 Standout
Oxidative Stress
2017 Standout
SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase
2019 StandoutNobel
Pathophysiology of Migraine: A Disorder of Sensory Processing
2017 Standout
The Nrf2-Antioxidant Response Element Signaling Pathway and Its Activation by Oxidative Stress
2009 Standout
Engineering precision nanoparticles for drug delivery
2020 Standout
Achieving Normothermia in Patients With Febrile Subarachnoid Hemorrhage: Feasibility and Safety of a Novel Intravascular Cooling Catheter
2004
Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain
1999 Standout
An Nrf2/Small Maf Heterodimer Mediates the Induction of Phase II Detoxifying Enzyme Genes through Antioxidant Response Elements
1997 Standout
Cancer chemoprevention with dietary phytochemicals
2003 Standout
Oxidative stress, inflammation, and cancer: How are they linked?
2010 Standout
Melanin Pigmentation in Mammalian Skin and Its Hormonal Regulation
2004 Standout
Oxidative Stress Hypothesis in Alzheimer's Disease
1997 Standout
Descending control of pain
2002 Standout
The NLRP3 inflammasome: molecular activation and regulation to therapeutics
2019 Standout
Keap1-dependent Proteasomal Degradation of Transcription Factor Nrf2 Contributes to the Negative Regulation of Antioxidant Response Element-driven Gene Expression
2003 Standout
Nordihydroguaiaretic acid protects hippocampal neurons against amyloid β-peptide toxicity, and attenuates free radical and calcium accumulation
1994
WNT signalling pathways as therapeutic targets in cancer
2012 Standout
Mechanical, thermal and formalin-induced nociception is differentially altered in 5-HT1A−/−, 5-HT1B−/−, 5-HT2A−/−, 5-HT3A−/− and 5-HTT−/− knock-out male mice
2007 StandoutNobel
Trends in GPCR drug discovery: new agents, targets and indications
2017 Standout
Locomotor networks are targets of modulation by sensory transient receptor potential vanilloid 1 and transient receptor potential melastatin 8 channels
2009 StandoutNobel
Structural Basis for Defects of Keap1 Activity Provoked by Its Point Mutations in Lung Cancer
2006 Standout
Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway
2011 Standout
Platelet-derived growth factor (PDGF): Actions and mechanisms in vascular smooth muscle
1996
Fever Increased In-Hospital Mortality After Subarachnoid Hemorrhage
2011
ESDN, a Novel Neuropilin-like Membrane Protein Cloned from Vascular Cells with the Longest Secretory Signal Sequence among Eukaryotes, Is Up-regulated after Vascular Injury
2001 StandoutNobel
Heme Oxygenase-1/Carbon Monoxide: From Basic Science to Therapeutic Applications
2006 Standout
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
Characterization of the serotoninergic system in the C57BL/6 mouse skin
2003
New paradigms in GPCR drug discovery
2015
Plant Polyphenols: Chemical Properties, Biological Activities, and Synthesis
2011 Standout
Assessment of lipid peroxidation by measuring malondialdehyde (MDA) and relatives in biological samples: Analytical and biological challenges
2016 Standout
Nrf2 Redirects Glucose and Glutamine into Anabolic Pathways in Metabolic Reprogramming
2012 Standout
Hyperthermia and fever control in brain injury
2009
The chemistry and biology of organic guanidine derivatives
2008
7-Ketocholesterol induces apoptosis in differentiated PC12 cells via reactive oxygen species-dependent activation of NF-κB and Akt pathways
2010
Interference of Frizzled 1 (FZD1) reverses multidrug resistance in breast cancer cells through the Wnt/β-catenin pathway
2012
Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases
2019 Standout
The densely fluorinated nanospace of a porous coordination polymer composed of perfluorobutyl-functionalized ligands
2014 StandoutNobel
Non-infectious fever in the neurological intensive care unit: incidence, causes and predictors
2007
Blockade of swelling‐induced chloride channels by phenol derivatives
1996
The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1
2010 Standout
Metabolites Are Key to Understanding Health Effects of Wine Polyphenolics
2009
Nrf2 activation improves experimental rheumatoid arthritis
2023 StandoutNobel
Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants
2002 Standout
Iron Catalysis in Organic Synthesis
2015 Standout
Highly Selective Formation of β‐Glycosides of N‐Acetylglucosamine Using Catalytic Iron(III) Triflate
2012
Role of Nrf2 in Oxidative Stress and Toxicity
2013 Standout
Assessing mitochondrial dysfunction in cells
2011 Standout
Fever after subarachnoid hemorrhage
2007
Mitochondrial uncouplers with an extraordinary dynamic range
2007
Contribution of Organically Grown Crops to Human Health
2014
Surface-Enhanced Raman Spectroscopy for Bioanalysis: Reliability and Challenges
2018 Standout
Development of Multifunctional Molecules as Potential Therapeutic Candidates for Alzheimer’s Disease, Parkinson’s Disease, and Amyotrophic Lateral Sclerosis in the Last Decade
2018
Cell Survival Responses to Environmental Stresses Via the Keap1-Nrf2-ARE Pathway
2006 Standout
Merobatzelladines A and B, Anti-Infective Tricyclic Guanidines from a Marine Sponge Monanchora sp.
2009 StandoutNobel
Neuropathic Pain: From Mechanisms to Treatment
2020 Standout
Human plasma concentrations of malondialdehyde (MDA) and the F2-isoprostane 15(S)-8-iso-PGF2α may be markedly compromised by hemolysis: Evidence by GC-MS/MS and potential analytical and biological ramifications
2009
Dietary and Policy Priorities for Cardiovascular Disease, Diabetes, and Obesity
2016 Standout
Oxygen Carriers (“Blood Substitutes”)Raison d'Etre, Chemistry, and Some PhysiologyBlut ist ein ganz besondrer Saft
2001
Kinetic Target-Guided Synthesis in Drug Discovery and Chemical Biology: A Comprehensive Facts and Figures Survey
2016
The KEAP1-NRF2 System: a Thiol-Based Sensor-Effector Apparatus for Maintaining Redox Homeostasis
2018 Standout
Aerobic Copper-Catalyzed Organic Reactions
2013 Standout
Comparative antioxidant activities of carotenoids measured by ferric reducing antioxidant power (FRAP), ABTS bleaching assay (αTEAC), DPPH assay and peroxyl radical scavenging assay
2011 Standout
‘Radical-controlled’ oxidative polymerization of m-cresol catalyzed by μ-η2:η2-peroxo dicopper(II) complex
2000
Ferroptosis as a target for protection against cardiomyopathy
2019 Standout
Part 8: Post–Cardiac Arrest Care
2015 Standout
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
Development of an Acrylate Derivative Targeting the NLRP3 Inflammasome for the Treatment of Inflammatory Bowel Disease
2017
Guidelines for the Management of Aneurysmal Subarachnoid Hemorrhage
2012 Standout
Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
2016 Standout
Functional Significance of Cell Volume Regulatory Mechanisms
1998 Standout
Oxidative polymerization of phenols revisited
2003
Synthesis of Imidazo[4,5-b]pyridines and Imidazo[4,5-b]pyrazines by Palladium Catalyzed Amidation of 2-Chloro-3-amino-heterocycles
2012
Uptake of Engineered Gold Nanoparticles into Mammalian Cells
2013
Food Processing and the Mediterranean Diet
2015
“Radical-Controlled” Oxidative Polymerization of 4-Phenoxyphenol by a Tyrosinase Model Complex Catalyst to Poly(1,4-phenylene oxide)
2000
Active Cellular and Subcellular Targeting of Nanoparticles for Drug Delivery
2019
Iron salt-catalyzed cascade type one-pot double alkylation of indole with vinyl ketones
2010
Hydrogen Sulfide Mediates Cardioprotection Through Nrf2 Signaling
2009 Standout
Works of Massimo Valoti being referenced
Carotenoids: Actual knowledge on food sources, intakes, stability and bioavailability and their protective role in humans
2008 Standout
Calcium antagonist and antiperoxidant properties of some hindered phenols
1993
Folate-targeted liposomal nitrooxy-doxorubicin: An effective tool against P-glycoprotein-positive and folate receptor-positive tumors
2017
[37] Cyclooxygenase activity of hemoglobin
1994
Rectal temperature and prostaglandin E 2 increase in cerebrospinal fluid of conscious rabbits after intracerebroventricular injection of hemoglobin
1999
Synthesis and antiperoxidant activity of new phenolic O-glycosides
2001
Anti‐apoptotic effect of Mao‐B inhibitor PF9601N [N‐(2‐propynyl)‐2‐(5‐benzyloxy‐indolyl) methylamine] is mediated by p53 pathway inhibition in MPP+‐treated SH‐SY5Y human dopaminergic cells
2008
Evidence of a coupled mechanism between monoamine oxidase and peroxidase in the metabolism of tyramine by rat intestinal mitochondria
1998
Key Targets for Multi-Target Ligands Designed to Combat Neurodegeneration
2016
Cancer Cell Permeability-Glycoprotein as a Target of MDR Reverters: Possible Role of Novel Dihydropyridine Derivatives
2006
Red wine alcohol promotes quercetin absorption and directs its metabolism towards isorhamnetin and tamarixetin in rat intestine in vitro
2006
Investigations on the 4‐Quinolone‐3‐Carboxylic Acid Motif Part 5: Modulation of the Physicochemical Profile of a Set of Potent and Selective Cannabinoid‐2 Receptor Ligands through a Bioisosteric Approach
2012
Free radical intermediates during peroxidase oxidation of 2-t-butyl-4-methoxyphenol, 2,6-di-t-butyl-4-methylphenol, and related phenol compounds
1989
Dehalogenation and N-dealkylation of chlorpromazine as revealed by plasma concentrations of metabolites in a population of chronically medicated schizophrenics.
1993
Synthesis and Pharmacological Characterization of 2-(Acylamino)thiophene Derivatives as Metabolically Stable, Orally Effective, Positive Allosteric Modulators of the GABAB Receptor
2013
Synthesis and Biological Evaluation of Amidine, Guanidine, and Thiourea Derivatives of 2-Amino(6-trifluoromethoxy)benzothiazole as Neuroprotective Agents Potentially Useful in Brain Diseases
2009
The interaction of antioxidants and structurally related compounds with mitochondrial oxidative phosphorylation.
1991
Design, Synthesis, Biological Activity, and ADME Properties of Pyrazolo[3,4-d]pyrimidines Active in Hypoxic Human Leukemia Cells: A Lead Optimization Study
2011
Gold Nanoparticles Uptake and Cytotoxicity Assessed on Rat Liver Precision-Cut Slices
2012
Further Studies on Imidazo[4,5-b]pyridine AT1Angiotensin II Receptor Antagonists. Effects of the Transformation of the 4-Phenylquinoline Backbone into 4-Phenylisoquinolinone or 1-Phenylindene Scaffolds
2006