Citation Impact
Citing Papers
Jinx , an MCMV susceptibility phenotype caused by disruption of Unc13d : a mouse model of type 3 familial hemophagocytic lymphohistiocytosis
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Deletion of the p66 Shc longevity gene reduces systemic and tissue oxidative stress, vascular cell apoptosis, and early atherogenesis in mice fed a high-fat diet
2003
The microbiota regulates type 2 immunity through RORγt + T cells
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Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroids
2007
Secretory phospholipase A2-IIa is involved in prostate cancer progression and may potentially serve as a biomarker for prostate cancer
2010
Functional diversity of helper T lymphocytes
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Phospholipase A2 subclasses in acute respiratory distress syndrome
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Mice lacking serum paraoxonase are susceptible to organophosphate toxicity and atherosclerosis
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Membranous nephropathy: recent travels and new roads ahead
2010
Arachidonic acid as a bioactive molecule
2001
Metal-Substituted Protein MRI Contrast Agents Engineered for Enhanced Relaxivity and Ligand Sensitivity
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Do basophils play a role in immunity against parasites?
2001
NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21
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Degradation of a Calcium Influx Factor (CIF) Can Be Blocked by Phosphatase Inhibitors or Chelation of Ca2+
1995 StandoutNobel
Secretory lysosomes
2002
Nucleotide signalling during inflammation
2014 StandoutNature
Activation of human mast cells through the high affinity IgG receptor
2002
Basophils: what they 'can do' versus what they 'actually do'
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Differential hydrolysis of molecular species of lipoprotein phosphatidylcholine by groups IIA, V and X secretory phospholipases A
2005
Purinergic Signaling in the Airways
2012
Phospholipase A2s: Developing drug targets for atherosclerosis
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Role of Group VIA Calcium-independent Phospholipase A2 in Arachidonic Acid Release, Phospholipid Fatty Acid Incorporation, and Apoptosis in U937 Cells Responding to Hydrogen Peroxide
2004
Substrate Binding Is the Rate-limiting Step in Thromboxane Synthase Catalysis
2001
Extracellular phospholipases in atherosclerosis
2010
High density associated enzymes: their role in vascular biology
1998
Τhe role of lipoprotein-associated phospholipase A2 in atherosclerosis may depend on its lipoprotein carrier in plasma
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Pulmonary immune cells in health and disease: the eosinophil leucocyte (Part II)
1994
IgE and mast cells in allergic disease
2012 Standout
Inhibitors of cyclo-oxygenase-2 and secretory phospholipase A2 preserve bone architecture following ovariectomy in adult rats
2006
Ubiquitin-mediated Processing of NF-κB Transcriptional Activator Precursor p105
1995 StandoutNobel
Inhibition of secretory phospholipase A. 1-Design, synthesis and structure–activity relationship studies starting from 4-tetradecyloxybenzamidine to obtain specific inhibitors of group II sPLAs
2005
Peptidylproline cis‐trans‐isomerases: immunophilins
1993
A potent and selective inhibitor of group IIa secretory phospholipase A2 protects rats from TNBS-induced colitis
2005
Angiotensin II regulates cellular immune responses through a calcineurin-dependent pathway
1999 StandoutNobel
Revised nomenclature for allergy for global use: Report of the Nomenclature Review Committee of the World Allergy Organization, October 2003
2004 Standout
Plasma platelet activating factor-acetylhydrolase (PAF-AH)
2003
The Chemokine System in Innate Immunity
2015
Platelet-activating factor acetylhydrolase and transacetylase activities in human plasma low-density lipoprotein
2001
IgG4-Related Disease
2012 Standout
Alternative mechanisms for tiotropium
2009
Nonresolving Inflammation
2010 Standout
The proinflammatory mediator Platelet Activating Factor is an effective substrate for human group X secreted phospholipase A2
2006
New Concepts about the Mast Cell
1993
Myasthenia Gravis
1994 Standout
Transgenic Expression of Group V, but Not Group X, Secreted Phospholipase A2 in Mice Leads to Neonatal Lethality because of Lung Dysfunction
2006
Mitochondria, Oxidants, and Aging
2005 Standout
Antioxidants and Atherosclerotic Heart Disease
1997 Standout
Deficiency of platelet-activating factor acetylhydrolase is a severity factor for asthma
1999
Impact of a Soluble Phospholipase A2Inhibitor on Inhaled Allergen Challenge in Subjects with Asthma
2005
Bioactive products generated by Group V sPLA2 hydrolysis of LDL activate macrophages to secrete pro-inflammatory cytokines
2010
Fatal and Near-Fatal Anaphylactic Reactions to Food in Children and Adolescents
1992 Standout
Antibacterial actions of secreted phospholipases A2. Review
2008
Apop-1, a Novel Protein Inducing Cyclophilin D-dependent but Bax/Bak-related Channel-independent Apoptosis
2006 StandoutNobel
Blockade of Human Group X Secreted Phospholipase A2 (GX-sPLA2)-induced Airway Inflammation and Hyperresponsiveness in a Mouse Asthma Model by a Selective GX-sPLA2 Inhibitor
2011
Effect of platelet activating factor-acetylhydrolase on the formation and action of minimally oxidized low density lipoprotein.
1995
The development of allergic inflammation
2008 StandoutNature
The mast cell IgG receptors and their roles in tissue inflammation
2007
Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC Phases One and Three repeat multicountry cross-sectional surveys
2006 Standout
The mechanism of action of cyclosporin A and FK506
1992 Standout
Fatty streak formation occurs in human fetal aortas and is greatly enhanced by maternal hypercholesterolemia. Intimal accumulation of low density lipoprotein and its oxidation precede monocyte recruitment into early atherosclerotic lesions.
1997
Signal transduction by lymphocyte antigen receptors
1994 Standout
Mammalian platelet-activating factor acetylhydrolases
1996
Calcium‐independent phospholipase A2‐mediated formation of 1,2‐diarachidonoyl‐glycerophosphoinositol in monocytes
2008
Secretory phospholipase A2 of group IIA: Is it an offensive or a defensive player during atherosclerosis and other inflammatory diseases?
2005
The phospholipase A2 superfamily and its group numbering system
2006 Standout
M-Type Phospholipase A 2 Receptor as Target Antigen in Idiopathic Membranous Nephropathy
2009 Standout
Drug target validation and identification of secondary drug target effects using DNA microarrays
1998 StandoutNobel
Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A
1991 Nature
Atherosclerosis — An Inflammatory Disease
1999 Standout
The role of histamine H1 and H4 receptors in allergic inflammation: the search for new antihistamines
2008
Mucosal immunity and allergic responses: lack of regulation and/or lack of microbial stimulation?
2005
Severe Adverse Cutaneous Reactions to Drugs
1994 Standout
Inflammation in atherosclerosis
2002 StandoutNature
Inhibition of lipoprotein‐associated phospholipase A2 diminishes the death‐inducing effects of oxidised LDL on human monocyte‐macrophages
2001
Blockade of arachidonic acid incorporation into phospholipids induces apoptosis in U937 promonocytic cells
2005
Basophil recruitment and IL-4 production during human allergen-induced late asthma
2001
Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation
1992 StandoutNature
Airway Mucus Function and Dysfunction
2010 Standout
Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse
1995 StandoutNobel
The cellular biology of eosinophil eicosanoid formation and function
2002
FcεRI-Dependent Signaling Pathways in Human Mast Cells
2001
Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes
1991 Standout
Insulin Secretory Responses and Phospholipid Composition of Pancreatic Islets from Mice That Do Not Express Group VIA Phospholipase A2 and Effects of Metabolic Stress on Glucose Homeostasis
2006
Atherosclerosis
2000 StandoutNature
Function and Inhibition of Intracellular Calcium-independent Phospholipase A2
1997
Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity
2010 StandoutNature
Mast cells in the pathogenesis of rheumatic diseases and as potential targets for anti‐rheumatic therapy
2007
Analysis of expression of secreted phospholipases A2 in mouse tissues at protein and mRNA levels
2006
The Prognostic Value of C-Reactive Protein and Serum Amyloid A Protein in Severe Unstable Angina
1994 Standout
Biology of Platelet-activating Factor Acetylhydrolase (PAF-AH, Lipoprotein Associated Phospholipase A2)
2008
Atherosclerosis
2001 Standout
Relationship between levels of secreted phospholipase A2 groups IIA and X in the airways and asthma severity
2011
Release of Free F2-isoprostanes from Esterified Phospholipids Is Catalyzed by Intracellular and Plasma Platelet-activating Factor Acetylhydrolases
2005
Calcium-independent phospholipase A2 and apoptosis
2006
A Calcineurin-Dependent Transcriptional Pathway for Cardiac Hypertrophy
1998 Standout
The role of T lymphocytes in the pathogenesis of asthma
2003
Bromoenol Lactone Inhibits Magnesium-dependent Phosphatidate Phosphohydrolase and Blocks Triacylglycerol Biosynthesis in Mouse P388D1 Macrophages
1996
IgE, mast cells, basophils, and eosinophils
2010 Standout
Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19
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BMS-229724 Is a Tight-Binding Inhibitor of Cytosolic Phospholipase A2 That Acts at the Lipid/Water Interface and Possesses Anti-Inflammatory Activity in Skin Inflammation Models
2001
Novel Mammalian Group XII Secreted Phospholipase A2Lacking Enzymatic Activity,
2003
Increased urinary leukotriene excretion in patients with cardiac ischemia. In vivo evidence for 5-lipoxygenase activation.
1992
Leukocyte lipid body formation and eicosanoid generation: cyclooxygenase-independent inhibition by aspirin.
1996 StandoutNobel
Mast Cells and Basophils
2004
Mechanisms of platelet-activating factor-induced lipid body formation: requisite roles for 5-lipoxygenase and de novo protein synthesis in the compartmentalization of neutrophil lipids.
1996
Biochemistry and Physiology of Mammalian Secreted Phospholipases A2
2008
Differential determination of phospholipase A2 and PAF-acetylhydrolase in biological fluids using fluorescent substrates
1999
Bombesin stimulates distinct time-dependent changes in the sn-1,2-diradylglycerol molecular species profile from Swiss 3T3 fibroblasts as analysed by 3,5-dinitrobenzoyl derivatization and h.p.l.c. separation
1993
Group X Secretory Phospholipase A 2 Negatively Regulates ABCA1 and ABCG1 Expression and Cholesterol Efflux in Macrophages
2010
Cooperation Between Secretory Phospholipase A 2 and TNF-Receptor Superfamily Signaling
2002
Intracellular Signaling by Hydrolysis of Phospholipids and Activation of Protein Kinase C
1992 StandoutScience
Group IB Secretory Phospholipase A2 Stimulates CXC Chemokine Ligand 8 Production via ERK and NF-κB in Human Neutrophils
2004
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
In Vivo Protective Role of Human Group IIA Phospholipase A2 against Experimental Anthrax
2005
The immunosuppressant FK506 inhibits amino acid import in Saccharomyces cerevisiae.
1993
Lipoprotein-Associated and Secreted Phospholipases A 2 in Cardiovascular Disease
2010
Novel Peptide Inhibitors of Human Secretory Phospholipase A2 with Antiinflammatory Activity: Solution Structure and Molecular Modeling
2007
In Silico-Guided Target Identification of a Scaffold-Focused Library: 1,3,5-Triazepan-2,6-diones as Novel Phospholipase A2 Inhibitors
2006
Pharmacological and immunohistochemical evidence for a functional nitric oxide synthase system in rat peritoneal eosinophils
1997 StandoutNobel
Adenovirus-Mediated Gene Transfer of Human Platelet-Activating Factor–Acetylhydrolase Prevents Injury-Induced Neointima Formation and Reduces Spontaneous Atherosclerosis in Apolipoprotein E–Deficient Mice
2001
The Yin and Yang of Oxidation in the Development of the Fatty Streak
1996 Standout
Skeletal Muscle Group VIA Phospholipase A2 (iPLA2β): Expression and Role in Fatty Acid Oxidation
2008
Emerging roles of secreted phospholipase A2 enzymes: Lessons from transgenic and knockout mice
2010
Platelet-Activating Factor and Related Lipid Mediators
2000
Regulatory roles of IL-10–producing human follicular T cells
2019 StandoutNobel
Tissue-specific contributions of Tmem79 to atopic dermatitis and mast cell-mediated histaminergic itch
2018 StandoutNobel
Is cyclophilin involved in the immunosuppressive and nephrotoxic mechanism of action of cyclosporin A?
1991
Phospholipase A2Enzymes: Physical Structure, Biological Function, Disease Implication, Chemical Inhibition, and Therapeutic Intervention
2011 Standout
Anaphylaxis
1991
Lipopolysaccharide priming of alveolar macrophages for enhanced synthesis of prostanoids involves induction of a novel prostaglandin H synthase.
1992
JNK1 controls mast cell degranulation and IL-1β production in inflammatory arthritis
2010 StandoutNobel
Atherogenic properties of LDL particles modified by human group X secreted phospholipase A2 on human endothelial cell function
2006
Phenotypic and functional analysis of positive selection in the gamma/delta T cell lineage.
1993 StandoutNobel
Structure and Chemistry of Cytochrome P450
2005 Standout
The immunosuppressant drug FTY720 inhibits cytosolic phospholipase A2 independently of sphingosine-1-phosphate receptors
2006
Works of Massimo Triggiani being referenced
Activation of human inflammatory cells by secreted phospholipases A2
2006
Arachidonic acid metabolism during antigen and ionophore activation of the mouse bone marrow derived mast cell
1991
Relative amounts of 1-O-alkyl- and 1-acyl-2-acetyl-sn-glycero-3-phosphocholine in stimulated endothelial cells
1992
Secretory phospholipases A2 in inflammatory and allergic diseases: Not just enzymes
2005
Cardiovascular and Metabolic Effects of Peptide Leukotrienes in Mana
1988
Control of arachidonate levels within inflammatory cells
1996
Lung mast cells are a source of secreted phospholipases A2
2009
Mast cells and basophils: friends as well as foes in bronchial asthma?
2004
The histamine-cytokine network in allergic inflammation
2003
Secretory Phospholipases A<sub>2</sub> as Multivalent Mediators of Inflammatory and Allergic Disorders
2003
Secreted phospholipases A2: A proinflammatory connection between macrophages and mast cells in the human lung
2009
Role of human FcεRI+ cells in HIV‐1 infection
2001
Cyclosporin a inhibits the release of histamine and peptide leukotriene C4 from human lung mast cells
1988
Human mast cells and basophils in HIV-1 infection
2001
Inhibition of Histamine and Prostaglandin D<sub>2</sub> Release from Human Lung Mast Cells by Ciclosporin A
1989
Secretory phospholipases A2 induce cytokine release from blood and synovial fluid monocytes
2002
Oxidative structural modifications of low density lipoprotein in homozygous familial hypercholesterolemia
1995
Differentiation of monocytes into macrophages induces the upregulation of histamine H1 receptor
2006
The immunoglobulin superantigen-binding site of HIV-1 gp120 activates human basophils
2000
Arachidonic acid metabolism in inflammatory cells of patients with bronchial asthma
2000
Expression of phospholipases A2 in primary human lung macrophages
2008
Histamine-Induced Activation of Human Lung Macrophages
2001
Oxygen radicals inhibit human plasma acetylhydrolase, the enzyme that catabolizes platelet-activating factor.
1994
Molecular and Cellular Biology of Mast Cells and Basophils
1997
Role of Human Mast Cells and Basophils in Bronchial Asthma
2005
Signaling events involved in cytokine and chemokine production induced by secretory phospholipase A2 in human lung macrophages
2006
Role of Arachidonyl Triglycerides within Lipid Bodies in Eicosanoid Formation by Human Polymorphonuclear Cells
1999
Characterization of Platelet-activating Factor Acetylhydrolase in Human Bronchoalveolar Lavage
1997
Antigen-induced generation of lyso-phospholipids in human airways.
1996
Activation of Cytokine Production by Secreted Phospholipase A2 in Human Lung Macrophages Expressing the M-Type Receptor
2005
Differential roles for triglyceride and phospholipid pools of arachidonic acid in human lung macrophages.
1994
Metabolism of Lipid Mediators in Human Basophils and Mast Cells
1995
Ciclosporin A Inhibits Mediator Release from Human FcεRI<sup>+</sup> Cells by Interacting with Cyclophilin
1991
Differential synthesis of 1-acyl-2-acetyl-sn-glycero-3-phosphocholine and platelet-activating factor by human inflammatory cells.
1991
Secretory Phospholipases A2 Induce β-Glucuronidase Release and IL-6 Production from Human Lung Macrophages
2000
Histamine Induces Exocytosis and IL-6 Production from Human Lung Macrophages Through Interaction with H1 Receptors
2001
Recent advances in our understanding of the biochemical interactions between platelet‐activating factor and arachidonic acid
1991
Secretory Phospholipases A2 Activate Selective Functions in Human Eosinophils
2003
Synthesis of 1-acyl-2-acetyl-sn-glycero-3-phosphocholine by an enriched preparation of the human lung mast cell.
1990
Oxidative/nitrosative stress selectively altered A 2B adenosine receptors in chronic obstructive pulmonary disease
2009
Migration of human inflammatory cells into the lung results in the remodeling of arachidonic acid into a triglyceride pool.
1995
Cyclosporin A rapidly inhibits mediator release from human basophils presumably by interacting with cyclophilin.
1990