Citation Impact
Citing Papers
Associations between insulin resistance and TNF-α in plasma, skeletal muscle and adipose tissue in humans with and without type 2 diabetes
2007
Exercise induces expression of leukaemia inhibitory factor in human skeletal muscle
2008
Dynamics of the Skeletal Muscle Secretome during Myoblast Differentiation
2010
Human IL6 enhances leptin action in mice
2009
Interleukin‐6 production in contracting human skeletal muscle is influenced by pre‐exercise muscle glycogen content
2001
siRNA-based gene silencing reveals specialized roles of IRS-1/Akt2 and IRS-2/Akt1 in glucose and lipid metabolism in human skeletal muscle
2006
Redox Mechanisms of Muscle Dysfunction in Inflammatory Disease
2005
Cytokine regulation of skeletal muscle fatty acid metabolism: effect of interleukin-6 and tumor necrosis factor-α
2004
The metabolic role of IL-6 produced during exercise: is IL-6 an exercise factor?
2004
Skeletal Muscle Fatigue: Cellular Mechanisms
2008 Standout
Inflammation and metabolic disorders
2006 StandoutNature
Inflammatory links between obesity and metabolic disease
2011 Standout
The effects of carbohydrate supplementation during the second of two prolonged cycling bouts on immunoendocrine responses
2005
Hepatosplanchnic clearance of interleukin-6 in humans during exercise
2003
A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis
2012 StandoutNature
AMPK: guardian of metabolism and mitochondrial homeostasis
2017 Standout
Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome
2015 StandoutNature
Exercise-Induced Oxidative Stress: Cellular Mechanisms and Impact on Muscle Force Production
2008 Standout
Lipolysis and lipid mobilization in human adipose tissue
2009
Exercise‐induced liver chemokine CXCL‐1 expression is linked to muscle‐derived interleukin‐6 expression
2011
Direct Cross-talk of Interleukin-6 and Insulin Signal Transduction via Insulin Receptor Substrate-1 in Skeletal Muscle Cells
2006
Chronic inflammation in the etiology of disease across the life span
2019 Standout
Interleukin-6 does/does not have a beneficial role in insulin sensitivity and glucose homeostasis
2006
Contraction-Induced Myokine Production and Release: Is Skeletal Muscle an Endocrine Organ?
2005
The diseasome of physical inactivity – and the role of myokines in muscle–fat cross talk
2009
Superantigen activates the gp130 receptor on adipocytes resulting in altered adipocyte metabolism
2014
Influence of gender, menstrual phase, and oral contraceptive use on immunological changes in response to prolonged cycling
2005
IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin
2004 Standout
Cellular senescence in aging and age-related disease: from mechanisms to therapy
2015 Standout
Interleukin‐6 release from the human brain during prolonged exercise
2002
Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes
2008 Standout
Skeletal muscle interleukin-6 and tumor necrosis factor-α release in healthy subjects and patients with type 2 diabetes at rest and during exercise
2003
Physiology and immunology of the cholinergic antiinflammatory pathway
2007 Standout
Local and systemic insulin resistance resulting from hepatic activation of IKK-β and NF-κB
2005 Standout
Exercise Standards for Testing and Training
2013 Standout
Skeletal muscle as an immunogenic organ
2008
The Adipose Tissue as an Endocrine Organ – A Nephrologists’ Perspective
2006
Adipocytes as regulators of energy balance and glucose homeostasis
2006 StandoutNature
Palmitate, but Not Unsaturated Fatty Acids, Induces the Expression of Interleukin-6 in Human Myotubes through Proteasome-dependent Activation of Nuclear Factor-κB
2004
Substantial elevation of interleukin‐6 concentration in peritendinous tissue, in contrast to muscle, following prolonged exercise in humans
2002
Adipose tissue as an endocrine organ
2009
Mechanisms of obesity-associated insulin resistance: many choices on the menu
2007
IL‐6 Gene Expression in Human Adipose Tissue in Response to Exercise – Effect of Carbohydrate Ingestion
2003
Trans Fatty Acids and Cardiovascular Disease
2006 Standout
Glutamine supplementation further enhances exercise-induced plasma IL-6
2003
The brain and immune system prompt energy shortage in chronic inflammation and ageing
2017
Interleukin-6 acts as insulin sensitizer on glycogen synthesis in human skeletal muscle cells by phosphorylation of Ser473 of Akt
2005
Skeletal Muscle Lipid Metabolism in Exercise and Insulin Resistance
2005
Inflammation, stress, and diabetes
2005 Standout
Inflammation and insulin resistance
2006 Standout
Type 2 diabetes as an inflammatory disease
2011 Standout
Obesity and the role of adipose tissue in inflammation and metabolism
2006
The role of interleukin‐6 in insulin resistance, body fat distribution and energy balance
2007
Adiponectin Enhances Insulin Sensitivity by Increasing Hepatic IRS-2 Expression via a Macrophage-Derived IL-6-Dependent Pathway
2011
Human nutrition, the gut microbiome and the immune system
2011 StandoutNature
Role of the Microbiota in Immunity and Inflammation
2014 Standout
Host Remodeling of the Gut Microbiome and Metabolic Changes during Pregnancy
2012 Standout
Two common structural motifs for TCR recognition by staphylococcal enterotoxins
2016 StandoutNobel
Supplementation with vitamins C and E inhibits the release of interleukin‐6 from contracting human skeletal muscle
2004
TLR4 links innate immunity and fatty acid–induced insulin resistance
2006 Standout
Orphan nuclear receptors: therapeutic opportunities in skeletal muscle
2006
Adipokines in inflammation and metabolic disease
2011 Standout
Interleukin-6 (IL-6) Induces Insulin Resistance in 3T3-L1 Adipocytes and Is, Like IL-8 and Tumor Necrosis Factor-α, Overexpressed in Human Fat Cells from Insulin-resistant Subjects
2003
Plasma levels of interleukin‐6 and C‐reactive protein are associated with physical inactivity independent of obesity
2006
Interleukin‐6 production in human subcutaneous abdominal adipose tissue: the effect of exercise
2002
Hormone-sensitive lipase is reduced in the adipose tissue of patients with type 2 diabetes mellitus: influence of IL-6 infusion
2004
Obesity and Cardiovascular Disease: A Scientific Statement From the American Heart Association
2021 Standout
Beneficial health effects of exercise – the role of IL-6 as a myokine
2007
Endurance training reduces the contraction-induced interleukin-6 mRNA expression in human skeletal muscle
2004
Effect of exercise, training, and glycogen availability on IL-6 receptor expression in human skeletal muscle
2005
Exercise induces interleukin‐8 receptor (CXCR2) expression in human skeletal muscle
2006
The Impact of the Gut Microbiota on Human Health: An Integrative View
2012 Standout
Muscle‐derived interleukin‐6: possible biological effects
2001
Searching for the exercise factor: is IL-6 a candidate?
2003
Inflammatory Markers and Exercise: Differences Related to Exercise Type
2003
Influence of TNF-α and IL-6 infusions on insulin sensitivity and expression of IL-18 in humans
2006
Elevated plasma interleukin-18 is a marker of insulin-resistance in type 2 diabetic and non-diabetic humans
2005
Reduced glycogen availability is associated with an elevation in HSP72 in contracting human skeletal muscle
2002
Exercise and hypoxia: effects on leukocytes and interleukin-6???shared mechanisms?
2002
Age-related inflammatory cytokines and disease
2003
The immunomodulating role of exercise in metabolic disease
2014
The effect of graded exercise on IL‐6 release and glucose uptake in human skeletal muscle
2003
gp130 receptor ligands as potential therapeutic targets for obesity
2007
Physiological roles of muscle-derived interleukin-6 in response to exercise
2007
Interleukin-6 and insulin sensitivity: friend or foe?
2004
Ciliary Neurotrophic Factor Prevents Acute Lipid-Induced Insulin Resistance by Attenuating Ceramide Accumulation and Phosphorylation of c-Jun N-Terminal Kinase in Peripheral Tissues
2006
An immune origin of type 2 diabetes?
2005
AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy
2007 Standout
Mechanisms for Insulin Resistance: Common Threads and Missing Links
2012 Standout
Glucose Ingestion Attenuates Interleukin‐6 Release from Contracting Skeletal Muscle in Humans
2003
Carbohydrate ingestion attenuates the increase in plasma interleukin‐6, but not skeletal muscle interleukin‐6 mRNA, during exercise in humans
2001
CNTF reverses obesity-induced insulin resistance by activating skeletal muscle AMPK
2006
Circulating IL‐6 Concentrations and Abdominal Adipocyte Isoproterenol‐stimulated Lipolysis in Women
2008
Regulation of IκB kinase and NF-κB in contracting adult rat skeletal muscle
2005
IL-6 enhances plasma IL-1ra, IL-10, and cortisol in humans
2003
Contraction‐induced interleukin‐6 transcription in rat slow‐type muscle is partly dependent on calcineurin activation
2006
Interleukin-6-deficient mice develop hepatic inflammation and systemic insulin resistance
2010
Ionomycin, but not physiologic doses of epinephrine, stimulates skeletal muscle Interleukin-6 mRNA expression and protein release
2004
Insulin resistance in patients with rheumatoid arthritis: effect of anti‐TNFα therapy
2007
Increase in interstitial interleukin-6 of human skeletal muscle with repetitive low-force exercise
2004
Inflammation, metaflammation and immunometabolic disorders
2017 StandoutNature
Muscle-derived interleukin-6: lipolytic, anti-inflammatory and immune regulatory effects
2003
Muscle as an Endocrine Organ: Focus on Muscle-Derived Interleukin-6
2008 Standout
Muscles, exercise and obesity: skeletal muscle as a secretory organ
2012 Standout
Obesity induces a phenotypic switch in adipose tissue macrophage polarization
2007 Standout
Thematic review series: Patient-Oriented Research. Free fatty acid metabolism in human obesity
2006
Adipose Tissue as an Endocrine Organ
2004 Standout
Interleukin-6 response to exercise during acute and chronic hypoxia
2004
Inflammasomes in health and disease
2012 StandoutNature
Cellular senescence: from physiology to pathology
2014 Standout
Calprotectin is released from human skeletal muscle tissue during exercise
2008
Production of Interleukin-6 by Skeletal Myotubes
2002
Analysis of global mRNA expression in human skeletal muscle during recovery from endurance exercise
2005
Pathophysiology of Human Visceral Obesity: An Update
2013 Standout
Strenuous exercise decreases the percentage of type 1 T cells in the circulation
2001
Cytokine gene expression in human skeletal muscle during concentric contraction: evidence that IL-8, like IL-6, is influenced by glycogen availability
2004
Nitric oxide production is a proximal signaling event controlling exercise‐induced mRNA expression in human skeletal muscle
2007
Effect of IL-6 on the insulin sensitivity in patients with type 2 diabetes
2014
Signaling Specificity of Interleukin-6 Action on Glucose and Lipid Metabolism in Skeletal Muscle
2006
Adipose Tissue-Derived Factors: Impact on Health and Disease
2006
The role of interleukins in insulin resistance and type 2 diabetes mellitus
2009
Quantity and Quality of Exercise for Developing and Maintaining Cardiorespiratory, Musculoskeletal, and Neuromotor Fitness in Apparently Healthy Adults
2011 Standout
IL-1β stimulates IL-6 production in cultured skeletal muscle cells through activation of MAP kinase signaling pathway and NF-κB
2003
Muscle‐derived interleukin‐6: mechanisms for activation and possible biological roles
2002
Mechanisms of Insulin Action and Insulin Resistance
2018 Standout
AMP-activated protein kinase — the fat controller of the energy railroadThis paper is one of a selection of papers published in this Special issue, entitled Second Messengers and Phosphoproteins—12th International Conference.
2006
Skeletal myocytes are a source of interleukin‐6 mRNA expression and protein release during contraction: evidence of fiber type specificity
2004
Myocardial Fatty Acid Metabolism in Health and Disease
2010 Standout
The biological roles of exercise-induced cytokines: IL-6, IL-8, and IL-15
2007
Interleukin-6 Increases Insulin-Stimulated Glucose Disposal in Humans and Glucose Uptake and Fatty Acid Oxidation In Vitro via AMP-Activated Protein Kinase
2006
High-intensity interval training attenuates the exercise-induced increase in plasma IL-6 in response to acute exercise
2009
Importance of Assessing Cardiorespiratory Fitness in Clinical Practice: A Case for Fitness as a Clinical Vital Sign: A Scientific Statement From the American Heart Association
2016 Standout
Interleukin-6 production by contracting human skeletal muscle: autocrine regulation by IL-6
2003
Transcriptional activation of the IL‐6 gene in human contracting skeletal muscle: influence of muscle glycogen content
2001
Interleukin-6 in acute exercise and training: what is the biological relevance?
2006
IL-7 is expressed and secreted by human skeletal muscle cells
2010
IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin
2004 Standout
The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria
2008 Standout
Spinal and Supraspinal Factors in Human Muscle Fatigue
2001 Standout
Cytokine Regulation of AMPK signalling
2009
Fiber type specific expression of TNF-alpha, IL-6 and IL-18 in human skeletal muscles.
2005
Enhanced plasma IL-6 and IL-1ra responses to repeated vs. single bouts of prolonged cycling in elite athletes
2002
Fiber Types in Mammalian Skeletal Muscles
2011 Standout
Exercise-induced muscle-derived cytokines inhibit mammary cancer cell growth
2011
Treatment of Obesity in Mitigating Metabolic Risk
2020
Increased mitochondrial content rescues in vivo muscle oxidative capacity in long‐term high‐fat‐diet‐fed rats
2009
IL-6 selectively stimulates fat metabolism in human skeletal muscle
2010
Interleukin-6 Directly Increases Glucose Metabolism in Resting Human Skeletal Muscle
2007
Inflammatory Mechanisms in Obesity
2011 Standout
Antioxidants attenuate the plasma cytokine response to exercise in humans
2003
Physical Activity and Public Health in Older Adults
2007 Standout
Physical Activity/Exercise and Type 2 Diabetes
2004
Inflammation and Activated Innate Immunity in the Pathogenesis of Type 2 Diabetes
2004
Interleukin-6 Regulation of AMP-Activated Protein Kinase
2006
Tumor Necrosis Factor-α Induces Skeletal Muscle Insulin Resistance in Healthy Human Subjects via Inhibition of Akt Substrate 160 Phosphorylation
2005
Interleukin-6 and Diabetes
2005
IL-6 and TNF-α expression in, and release from, contracting human skeletal muscle
2002
Role of myokines in exercise and metabolism
2007
AMPK regulation of fatty acid metabolism and mitochondrial biogenesis: Implications for obesity
2012
The anti-inflammatory effect of exercise: its role in diabetes and cardiovascular disease control
2006
Plasma Free Fatty Acid Storage in Subcutaneous and Visceral Adipose Tissue in Postabsorptive Women
2008
The anti-inflammatory effect of exercise
2005 Standout
Role of Extracellular Matrix in Adaptation of Tendon and Skeletal Muscle to Mechanical Loading
2004 Standout
Exercise Induces a Marked Increase in Plasma Follistatin: Evidence That Follistatin Is a Contraction-Induced Hepatokine
2010
Interleukin-6 release from human skeletal muscle during exercise: relation to AMPK activity
2003
Plasma interleukin-6 during strenuous exercise: role of epinephrine
2001
Works of Massimo Sacchetti being referenced
Regional Fat Metabolism in Human Splanchnic and Adipose Tissues; The Effect of Exercise
2002
Human Skeletal Muscle Fatty Acid and Glycerol Metabolism During Rest, Exercise and Recovery
2002
Skeletal muscle substrate metabolism during exercise: methodological considerations
1999
Intramuscular fatty acid metabolism in contracting and non‐contracting human skeletal muscle
2002
Recombinant human interleukin-6 infusion during low-intensity exercise does not enhance whole body lipolysis or fat oxidation in humans
2005
Acute interleukin-6 administration does not impair muscle glucose uptake or whole-body glucose disposal in healthy humans
2003
Interleukin-6 Stimulates Lipolysis and Fat Oxidation in Humans
2003
Interleukin-6 and tumor necrosis factor-? are not increased in patients with Type 2 diabetes: evidence that plasma interleukin-6 is related to fat mass and not insulin responsiveness
2004
Acute IL-6 treatment increases fatty acid turnover in elderly humans in vivo and in tissue culture in vitro
2004
Production of interleukin‐6 in contracting human skeletal muscles can account for the exercise‐induced increase in plasma interleukin‐6
2000
Whole body and leg acetate kinetics at rest, during exercise and recovery in humans
2002
Interleukin-6 Is a Novel Factor Mediating Glucose Homeostasis During Skeletal Muscle Contraction
2004
Acute interleukin-6 administration does not impair muscle glucose uptake or whole-body glucose disposal in healthy humans
2003