Citation Impact
Citing Papers
Cell culture-grown hepatitis C virus is infectious in vivo and can be recultured in vitro
2006 StandoutNobel
HCV Persistence and Immune Evasion in the Absence of Memory T Cell Help
2003 StandoutScienceNobel
Removing T-cell epitopes with computational protein design
2014 StandoutNobel
Characterization of a canine homolog of hepatitis C virus
2011 StandoutNobel
Trained immunity: A program of innate immune memory in health and disease
2016 StandoutScience
Evidence for a functional RNA element in the hepatitis C virus core gene
2007 StandoutNobel
Memory CD8 + T Cells Are Required for Protection from Persistent Hepatitis C Virus Infection
2003 StandoutNobel
Mouse models of acute and chronic hepacivirus infection
2017 StandoutScienceNobel
CD8 + T Cells Mediate Viral Clearance and Disease Pathogenesis during Acute Hepatitis B Virus Infection
2002
Immunotherapy of chronic hepatitis C virus infection with antibodies against programmed cell death-1 (PD-1)
2013 StandoutNobel
Innate and adaptive immune responses in chronic hepatitis B virus infections: towards restoration of immune control of viral infection
2011
What Once Was Lost, Now Is Found: Restoration of Hepatitis B-Specific Immunity After Treatment of Chronic Hepatitis B
1999
Five HLA-DP Molecules Frequently Expressed in the Worldwide Human Population Share a Common HLA Supertypic Binding Specificity
2010
Management of hepatitis B
2007
De novo design of modular and tunable protein biosensors
2021 StandoutNatureNobel
Immunotherapy of cancer in 2012
2012
Elevated serum levels of heat shock protein 70 can be detected after radiofrequency ablation
2011
The Class I-Restricted Cytotoxic T Lymphocyte Response to Predetermined Epitopes in the Hepatitis B and C Viruses
1994
Treatment predictors of a sustained virologic response in hepatitis B and C
2008
Hepatitis B Virus Infection — Natural History and Clinical Consequences
2004 Standout
The dynamics of T-lymphocyte responses during combination therapy for chronic hepatitis C virus infection
2002
Hepatitis C Virus–Specific CD4+T Cell Response after Liver Transplantation Occurs Early, Is Multispecific, Compartmentalizes to the Liver, and Does Not Correlate with Recurrent Disease
2001 StandoutNobel
Genetic variation in IL28B and spontaneous clearance of hepatitis C virus
2009 StandoutNature
Pathogenesis of hepatitis B virus infection
2010
Chronic Infections with Hepatotropic Viruses: Mechanisms of Impairment of Cellular Immune Responses
2007
Hepatitis C Virus Infection
2001 Standout
Adaptive immune responses in acute and chronic hepatitis C virus infection
2005 Nature
Role of the coinhibitory receptor cytotoxic T lymphocyte antigen-4 on apoptosis-Prone CD8 T cells in persistent hepatitis B virus infection
2011
Treatment triumphs
2014 StandoutNatureNobel
Different clinical behaviors of acute hepatitis C virus infection are associated with different vigor of the anti-viral cell-mediated immune response.
1996 StandoutNobel
The influence of T cell cross-reactivity on HCV-peptide specific human T cell response
2006
Systemic inflammatory response and downmodulation of peripheral CD25+Foxp3+ T-regulatory cells in patients undergoing radiofrequency thermal ablation for lung cancer
2009
New insight in the pathobiology of hepatitis B virus infection
2012
Predictors of HBeAg loss after lamivudine treatment for chronic hepatitis B
2002
Immunology of hepatitis B virus and hepatitis C virus infection
2005 Standout
Transmission of hepatitis C virus by saliva?
2005
Pretherapy alanine transaminase level as a determinant for hepatitis B e antigen seroconversion during lamivudine therapy in patients with chronic hepatitis B
1999
Hepatitis B virus infection
2009 Standout
Immunoregulatory effects of liver ablation therapies for the treatment of primary and metastatic liver malignancies
2008
Virus-induced type I IFN stimulates generation of immunoproteasomes at the site of infection
2006 StandoutNobel
PD-1/PD-L1 pathway and T-cell exhaustion in chronic hepatitis virus infection
2010
T‐cell response relative to genotype and ethnicity during antiviral therapy for chronic hepatitis C†
2005
Narrowed TCR repertoire and viral escape as a consequence of heterologous immunity
2006
Ex vivo analysis of human memory CD4 T cells specific for hepatitis C virus using MHC class II tetramers
2003
Radiofrequency Ablation and Immunostimulant OK-432: Combination Therapy Enhances Systemic Antitumor Immunity for Treatment of VX2 Lung Tumors in Rabbits
2013
Intratumoral modulation of the inducible co-stimulator ICOS by recombinant oncolytic virus promotes systemic anti-tumour immunity
2017 StandoutNobel
Prospects for a vaccine against the hepatitis C virus
2005 StandoutNatureNobel
Thermal ablation of tumours: biological mechanisms and advances in therapy
2014 Standout
Intrahepatic CD8+ T-Cell Failure During Chronic Hepatitis C Virus Infection *
2005
Lethal effect of the anti-Fas antibody in mice
1993 StandoutNature
Expression and detection of anti-HBs antibodies after hepatitis B virus infection or vaccination in the context of protective immunity
2019
Liver-Derived Hepatitis C Virus (HCV)-Specific CD4+ T Cells Recognize Multiple HCV Epitopes and Produce Interferon Gamma
2000 StandoutNobel
Entecavir is superior to lamivudine in reducing hepatitis B virus DNA in patients with chronic hepatitis B infection
2002
Quantitative analysis of the peripheral blood cytotoxic T lymphocyte response in patients with chronic hepatitis C virus infection.
1996 StandoutNobel
Adaptive Immunity to the Hepatitis C Virus
2010
CD4 T Lymphocyte Proliferative Responses to Hepatitis C Virus (HCV) Antigens in Patients Coinfected with HCV and Human Immunodeficiency Virus Who Responded to Anti‐HCV Treatment
2002 StandoutNobel
Differential Cd4+ and Cd8+ T–Cell Responsiveness in Hepatitis C Virus Infection
2001
Type 1/Type 2 Immunity in Infectious Diseases
2001
Pathogenesis of chronic viral hepatitis: differential roles of T cells and NK cells
2013
Evolution of hepatitis B virus during primary infection in humans: Transient generation of cytotoxic T-cell mutants
2004
Cytotoxic T lymphocyte response to hepatitis C virus-derived peptides containing the HLA A2.1 binding motif.
1995 StandoutNobel
Predicting HLA CD4 Immunogenicity in Human Populations
2018
Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals
2020 Standout
Restoring function in exhausted CD8 T cells during chronic viral infection
2005 StandoutNatureNobel
High Level of PD-1 Expression on Hepatitis C Virus (HCV)-Specific CD8 + and CD4 + T Cells during Acute HCV Infection, Irrespective of Clinical Outcome
2007
Negative regulators of T‐cell activation: potential targets for therapeutic intervention in cancer, autoimmune disease, and persistent infections
2009 StandoutNobel
Cancer immunotherapy comes of age
2011 StandoutNature
Recombinant Human Single Chain Fv Antibodies Recognizing Human Interleukin-6
1998 StandoutNobel
Occult hepatitis B virus infection
2006
Radiofrequency Ablation Induces Antigen-presenting Cell Infiltration and Amplification of Weak Tumor-induced Immunity
2009
Recurrence of hepatitis C virus after loss of virus-specific CD4+ T-cell response in acute hepatitis C
1999
A small jab – a big effect: nonspecific immunomodulation by vaccines
2013
Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting
2012 StandoutNatureNobel
Effect of HLA class II genotype on T helper lymphocyte responses and viral control in hepatitis C virus infection
2001
Radiofrequency ablation of colorectal liver metastases induces an inflammatory response in distant hepatic metastases but not in local accelerated outgrowth
2010
Understanding the hepatitis C virus life cycle paves the way for highly effective therapies
2013 StandoutNobel
Identification and Characterization of MAVS, a Mitochondrial Antiviral Signaling Protein that Activates NF-κB and IRF3
2005 Standout
Functional Restoration of HCV-Specific CD8 T Cells by PD-1 Blockade Is Defined by PD-1 Expression and Compartmentalization
2008
Coexpression of PD-1, 2B4, CD160 and KLRG1 on Exhausted HCV-Specific CD8+ T Cells Is Linked to Antigen Recognition and T Cell Differentiation
2010
CD4 T Helper Type 1 and Regulatory T Cells Induced against the Same Epitopes on the Core Protein in Hepatitis C Virus–Infected Persons
2002
T cell responses in hepatitis C: the good, the bad and the unconventional
2011
Increased circulating and intrahepatic T‐cell‐specific chemokines in chronic hepatitis C: relationship with the type of virological response to peginterferon plus ribavirin combination therapy
2004
HLA class I-restricted cytotoxic T lymphocytes specific for hepatitis C virus. Identification of multiple epitopes and characterization of patterns of cytokine release.
1995 StandoutNobel
Outcome of acute hepatitis C is related to virus-specific CD4 function and maturation of antiviral memory CD8 responses
2006
25 years of interferon-based treatment of chronic hepatitis C: an epoch coming to an end
2013
Spontaneous Clearance of Chronic Hepatitis C Virus Infection Is Associated With Appearance of Neutralizing Antibodies and Reversal of T-Cell Exhaustion
2012
Synergistic Reversal of Intrahepatic HCV-Specific CD8 T Cell Exhaustion by Combined PD-1/CTLA-4 Blockade
2009
Confronting Complexity: Real-World Immunodominance in Antiviral CD8+ T Cell Responses
2006
Hepatitis B Virus Biology and Pathogenesis
1992
A Randomized, Double-Blind, Placebo-Controlled Assessment of BMS-936558, a Fully Human Monoclonal Antibody to Programmed Death-1 (PD-1), in Patients with Chronic Hepatitis C Virus Infection
2013
Enhancing therapeutic vaccination by blocking PD-1–mediated inhibitory signals during chronic infection
2008
Flying Under the Radar: The Immunobiology of Hepatitis C
2006 StandoutNobel
T-cell response to structural and nonstructural hepatitis C virus antigens in persistent and self-limited hepatitis C virus infections
1994
Mutational escape from CD8+ T cell immunity
2005
Broad Repertoire of the CD4+ Th Cell Response in Spontaneously Controlled Hepatitis C Virus Infection Includes Dominant and Highly Promiscuous Epitopes
2005
PD-L1 negatively regulates CD4+CD25+Foxp3+ Tregs by limiting STAT-5 phosphorylation in patients chronically infected with HCV
2009
Nonoverlapping roles of PD-1 and FoxP3 in maintaining immune tolerance in a novel autoimmune pancreatitis mouse model
2016 StandoutNobel
Variable Patterns of Programmed Death-1 Expression on Fully Functional Memory T Cells after Spontaneous Resolution of Hepatitis C Virus Infection
2008 StandoutNobel
Rationally Engineered Therapeutic Proteins with Reduced Immunogenicity
2005
Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems
2014 StandoutNobel
Human broadly neutralizing antibodies to the envelope glycoprotein complex of hepatitis C virus
2012 StandoutNobel
Radiofrequency Ablation Combined with KS-IL2 Immunocytokine (EMD 273066) Results in an Enhanced Antitumor Effect against Murine Colon Adenocarcinoma
2009
Persistent hepatitis C virus infection in a chimpanzee is associated with emergence of a cytotoxic T lymphocyte escape variant.
1995 StandoutNobel
Conserved Hierarchy of Helper T Cell Responses in a Chimpanzee during Primary and Secondary Hepatitis C Virus Infections
2004
Early Interferon Therapy for Hepatitis C Virus Infection Rescues Polyfunctional, Long-Lived CD8 + Memory T Cells
2008
Hepatitis C virus (HCV) specific immune responses in anti-HCV positive patients without hepatitis C viraemia
1999
Simultaneous inhibition of two regulatory T-cell subsets enhanced Interleukin-15 efficacy in a prostate tumor model
2012 StandoutNobel
Ex vivo analysis of human memory CD4 T cells specific for hepatitis C virus using MHC class II tetramers
2003
Live attenuated yellow fever 17D infects human DCs and allows for presentation of endogenous and recombinant T cell epitopes
2005 StandoutNobel
IMMUNOBIOLOGY AND PATHOGENESIS OF VIRAL HEPATITIS
2006
Broad Specificity of Virus-Specific CD4+T-Helper-Cell Responses in Resolved Hepatitis C Virus Infection
2002
Spontaneous Recovery in Acute Human Hepatitis C Virus Infection: Functional T-Cell Thresholds and Relative Importance of CD4 Help
2007
Upregulation of PD-1 Expression on Circulating and Intrahepatic Hepatitis C Virus-Specific CD8+T Cells Associated with Reversible Immune Dysfunction
2007
Stealth and Cunning: Hepatitis B and Hepatitis C Viruses
2005
Hepatitis C virus non-structural protein 3-specific cellular immune responses following single or combined immunization with DNA or recombinant Semliki Forest virus particles
2002
High-Programmed Death-1 Levels on Hepatitis C Virus-Specific T Cells during Acute Infection Are Associated with Viral Persistence and Require Preservation of Cognate Antigen during Chronic Infection
2008
Cancer Genome Landscapes
2013 StandoutScience
Private aspects of heterologous immunity
2005
Reduction of Retrovirus-Induced Immunosuppression by In Vivo Modulation of T Cells during Acute Infection
2004 StandoutNobel
Cytotoxic T lymphocytes recognize an HLA-A2-restricted epitope within the hepatitis B virus nucleocapsid antigen.
1991
Cellular Immune Responses to the Hepatitis B Virus Polymerase
2004
PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors
2010 StandoutNobel
Cells transfected with human interleukin 6 cDNA acquire binding sites for the hepatitis B virus envelope protein.
1992
More Than Just Tumor Destruction: Immunomodulation by Thermal Ablation of Cancer
2011
The Frequency of CD127 + Hepatitis C Virus (HCV)-Specific T Cells but Not the Expression of Exhaustion Markers Predicts the Outcome of Acute HCV Infection
2013 StandoutNobel
Several Common HLA-DR Types Share Largely Overlapping Peptide Binding Repertoires
1998
PD‐1 modulates regulatory T cells and suppresses T‐cell responses in HCV‐associated lymphoma
2010
Dynamics of hepatitis B virus clearance in chimpanzees
2005
HLA class I-restricted human cytotoxic T cells recognize endogenously synthesized hepatitis B virus nucleocapsid antigen.
1991
Cell-Mediated Immunity and the Outcome of Hepatitis C Virus Infection
2004
A spatial view of the CD8+ T‐cell response: the case of HCV
2011
T-cell response to structural and nonstructural hepatitis C virus antigens in persistent and self-limited hepatitis C virus infections
1994
The microbial mimic poly IC induces durable and protective CD4+T cell immunity together with a dendritic cell targeted vaccine
2008 StandoutNobel
Induction of Primary Human T Cell Responses against Hepatitis C Virus-Derived Antigens NS3 or Core by Autologous Dendritic Cells Expressing Hepatitis C Virus Antigens: Potential for Vaccine and Immunotherapy
2006
Recombinant immunotoxin for cancer treatment with low immunogenicity by identification and silencing of human T-cell epitopes
2014 StandoutNobel
Works of Massimo Pilli being referenced
The Characteristics of the Cell-Mediated Immune Response Identify Different Profiles of Occult Hepatitis B Virus Infection
2008
Conserved hepatitis C virus sequences are highly immunogenic for CD4+ T cells: Implications for vaccine development
1999
HCV-Specific T-Cell Response in Relation to Viral Kinetics and Treatment Outcome (DITTO-HCV Project)
2007
Increased Immunostimulatory Activity Conferred to Antigen-presenting Cells by Exposure to Antigen Extract From Hepatocellular Carcinoma After Radiofrequency Thermal Ablation
2008
Intrahepatic and circulating HLA class II-restricted, hepatitis C virus-specific T cells: Functional characterization in patients with chronic hepatitis C
2002
Lamivudine treatment can restore T cell responsiveness in chronic hepatitis B.
1998
Radiofrequency Thermal Ablation for Hepatocellular Carcinoma Stimulates Autologous NK-Cell Response
2010
Transient restoration of anti-viral T cell responses induced by lamivudine therapy in chronic hepatitis B
2003
Lamivudine Treatment Can Overcome Cytotoxic T–Cell Hyporesponsiveness in Chronic Hepatitis B: New Perspectives for Immune Therapy
2001
Oral lichen planus pathogenesis: A role for the HCV-specific cellular immune response
2002
Identification of immunodominant T cell epitopes of the hepatitis B virus nucleocapsid antigen.
1991
Dysfunction and functional restoration of HCV-specific CD8 responses in chronic hepatitis C virus infection
2007
Long-lasting memory T cell responses following self-limited acute hepatitis B.
1996
Heterologous T cell immunity in severe hepatitis C virus infection
2005
Radiofrequency Thermal Ablation of Hepatocellular Carcinoma Liver Nodules Can Activate and Enhance Tumor-Specific T-Cell Responses
2006
Autopresentation of hepatitis B virus envelope antigens by T cells
1992
Oral lichen planus pathogenesis: A role for the HCV-specific cellular immune response
2002