Standout Papers
- Targeted disruption of the mouse beta1-adrenergic receptor gene: developmental and cardiovascular effects. (1996)
- Cardiovascular Regulation in Mice Lacking α 2 -Adrenergic Receptor Subtypes b and c (1996)
- Overexpression of angiotensin AT 1 receptor transgene in the mouse myocardium produces a lethal phenotype associated with myocyte hyperplasia and heart block (1997)
Citation Impact
Citing Papers
Partitioning of Lipid-Modified Monomeric GFPs into Membrane Microdomains of Live Cells
2002 StandoutScienceNobel
Role of LBPA and Alix in Multivesicular Liposome Formation and Endosome Organization
2004 StandoutScienceNobel
Generation of Pluripotent Stem Cells from Adult Mouse Liver and Stomach Cells
2008 StandoutScienceNobel
High-Resolution Crystal Structure of an Engineered Human β 2 -Adrenergic G Protein–Coupled Receptor
2007 StandoutScienceNobel
Spinophilin Blocks Arrestin Actions in Vitro and in Vivo at G Protein-Coupled Receptors
2004 StandoutScienceNobel
Keeping G Proteins at Bay: A Complex Between G Protein-Coupled Receptor Kinase 2 and Gßγ
2003 StandoutScienceNobel
Tumor Induction and Tissue Atrophy in Mice Lacking E2F-1
1996
Signaling from β1- and β2-adrenergic receptors is defined by differential interactions with PDE4
2008 StandoutNobel
Cardiovascular and Metabolic Alterations in Mice Lacking Both β1- and β2-Adrenergic Receptors
1999 StandoutNobel
The Third Intracellular Loop of α2-Adrenergic Receptors Determines Subtype Specificity of Arrestin Interaction
2002
Transcriptional regulator of programmed cell death encoded by Caenorhabditis elegans gene ces-2
1996 StandoutNatureNobel
Nitrous Oxide Produces Antinociceptive Response via α2Band/or α2CAdrenoceptor Subtypes in Mice
1999
Insights into α1 adrenoceptor function in health and disease from transgenic animal studies
2003
Targeted Disruption of the β2 Adrenergic Receptor Gene
1999 StandoutNobel
Excitotoxic Neuronal Death and the Pathogenesis of Huntington's Disease
2008
Cell-type Specific Targeting of the α2c-Adrenoceptor
2000 StandoutNobel
Early Transcription and Silencing of Cytokine Genes Underlie Polarization of T Helper Cell Subsets
2001
High-resolution crystal structure of human protease-activated receptor 1
2012 StandoutNatureNobel
Molecular Mechanisms of Human Hypertension
2001 Standout
Lessons from constitutively active mutants of G protein-coupled receptors
2002
Adrenergic Receptors From Molecular Structure to in vivo function
1997 StandoutNobel
The PDZ Binding Motif of the β1 Adrenergic Receptor Modulates Receptor Trafficking and Signaling in Cardiac Myocytes
2002 StandoutNobel
Anti–β1-adrenergic receptor antibodies and heart failure: causation, not just correlation
2004 StandoutNobel
Abnormal Regulation of the Sympathetic Nervous System in α2A-Adrenergic Receptor Knockout Mice
1999 StandoutNobel
A robust and high-throughput Cre reporting and characterization system for the whole mouse brain
2009 Standout
A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1
2011 StandoutNatureNobel
Deletion of a coordinate regulator of type 2 cytokine expression in mice
2001
The mechanosensory protein MEC-6 is a subunit of the C. elegans touch-cell degenerin channel
2002 StandoutNatureNobel
Differential Targeting of β-Adrenergic Receptor Subtypes and Adenylyl Cyclase to Cardiomyocyte Caveolae
2000
Important role of endogenous norepinephrine and epinephrine in the development of in vivo pressure-overload cardiac hypertrophy
2001
Physiological consequences of β-adrenergic receptor disruption
1998
Gene targeting — homing in on α2-adrenoceptor-subtype function
1997 StandoutNobel
Piezo2 is the major transducer of mechanical forces for touch sensation in mice
2014 StandoutNatureNobel
Two functionally distinct α2-adrenergic receptors regulate sympathetic neurotransmission
1999 StandoutNatureNobel
The structure and function of G-protein-coupled receptors
2009 StandoutNatureNobel
Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals
2003 Standout
Structure of a nanobody-stabilized active state of the β2 adrenoceptor
2011 StandoutNatureNobel
Targeting proteinase-activated receptors: therapeutic potential and challenges
2012
E2F-1 Functions in Mice to Promote Apoptosis and Suppress Proliferation
1996 StandoutNobel
MEC-2 regulates C. elegans DEG/ENaC channels needed for mechanosensation
2002 StandoutNatureNobel
Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids
2018 StandoutNobel
Genetic alteration of the α2-adrenoceptor subtype c in mice affects the development of behavioral despair and stress-induced increases in plasma corticosterone levels
1999 StandoutNobel
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
Molecular Basis of the Pleiotropic Phenotype of Mice Carrying the hypervariable yellow (Ahvy) Mutation at the agouti Locus
1996
Seven-transmembrane-spanning receptors and heart function
2002 StandoutNatureNobel
Instruction of Distinct CD4 T Helper Cell Fates by Different Notch Ligands on Antigen-Presenting Cells
2004 StandoutNobel
Caveolar Localization Dictates Physiologic Signaling of β2-Adrenoceptors in Neonatal Cardiac Myocytes
2002 StandoutNobel
Assessment of the role of α2‐adrenoceptor subtypes in the antinociceptive, sedative and hypothermic action of dexmedetomidine in transgenic mice
1997
Genetic and epigenetic stability of human pluripotent stem cells
2012
A common E2F-1 and p73 pathway mediates cell death induced by TCR activation
2000 StandoutNatureNobel
TRPA1 Mediates the Inflammatory Actions of Environmental Irritants and Proalgesic Agents
2006 StandoutNobel
fringe, a boundary-specific signaling molecule, mediates interactions between dorsal and ventral cells during Drosophila wing development
1994 StandoutNobel
Functional Coupling of Overexpressed β1-Adrenoceptors in the Myocardium of Transgenic Mice
1998
The Developmental and Physiological Consequences of Disrupting Genes Encoding β1 and β2 Adrenoceptors
1997 StandoutNobel
Selective Neuronal Degeneration in Huntington's Disease
2006
ERK Plays a Regulatory Role in Induction of LTP by Theta Frequency Stimulation and Its Modulation by β-Adrenergic Receptors
1999 StandoutNobel
In Vivo Mutation of the α2A-Adrenergic Receptor by Homologous Recombination Reveals the Role of This Receptor Subtype in Multiple Physiological Processes
1997
Genetic Alteration of α2C-Adrenoceptor Expression in Mice: Influence on Locomotor, Hypothermic, and Neurochemical Effects of Dexmedetomidine, a Subtype-Nonselective α2-Adrenoceptor Agonist
1997 StandoutNobel
Beta-adrenergic receptor subtype-specific signaling in cardiac myocytes from beta(1) and beta(2) adrenoceptor knockout mice.
2001 StandoutNobel
βAR Signaling Required for Diet-Induced Thermogenesis and Obesity Resistance
2002 StandoutScienceNobel
Hazardous air pollutants and asthma.
2002
Abnormal Vascular Function and Hypertension in Mice Deficient in Estrogen Receptor β
2002 StandoutScienceNobel
DNA-binding specificity and trans-activating potential of the leukemia-associated E2A-hepatic leukemia factor fusion protein.
1994
Extreme hydrops fetalis and cardiovascular abnormalities in mice lacking a functional Adrenomedullin gene
2001 StandoutNobel
Myocyte Adrenoceptor Signaling Pathways
2003 StandoutScienceNobel
Functional Consequences of Altering Myocardial Adrenergic Receptor Signaling
2000 StandoutNobel
Heterozygous α 2A -adrenergic receptor mice unveil unique therapeutic benefits of partial agonists
2002 StandoutNobel
Decreased blood pressure response in mice deficient of the α 1b -adrenergic receptor
1997
Coupling of β2-Adrenoceptor to GiProteins and Its Physiological Relevance in Murine Cardiac Myocytes
1999 StandoutNobel
G Protein-Coupled Receptors: Functional and Mechanistic Insights Through Altered Gene Expression
1998 StandoutNobel
The Phagosome Proteome
2001
The α2A-Adrenergic Receptor Plays a Protective Role in Mouse Behavioral Models of Depression and Anxiety
2001
Stomatin, flotillin-1, and flotillin-2 are major integral proteins of erythrocyte lipid rafts
2001
Mutation of the α2A-Adrenoceptor Impairs Working Memory Performance and Annuls Cognitive Enhancement by Guanfacine
2002 StandoutNobel
Progressive hypertrophy and heart failure in β 1 -adrenergic receptor transgenic mice
1999
Recent Advances in Cardiac β2-Adrenergic Signal Transduction
1999
E2A-HLF-Mediated Cell Transformation Requires both the trans-Activation Domains of E2A and the Leucine Zipper Dimerization Domain of HLF
1995
Model Organisms: New Insights Into Ion Channel and Transporter Function. Stomatin homologues interact inCaenorhabditis elegans
2001
A novel translational repressor mRNA is edited extensively in livers containing tumors caused by the transgene expression of the apoB mRNA-editing enzyme.
1997 StandoutNobel
Antinociceptive Action of Nitrous Oxide Is Mediated by Stimulation of Noradrenergic Neurons in the Brainstem and Activation of α2BAdrenoceptors
2000 StandoutNobel
Central Hypotensive Effects of the α 2a -Adrenergic Receptor Subtype
1996 Science
Pronounced pharmacologic deficits in M2 muscarinic acetylcholine receptor knockout mice
1999
In vivo hematopoietic stem cell modification by mRNA delivery
2023 StandoutScienceNobel
Anti–β1-adrenergic receptor antibodies and heart failure: causation, not just correlation
2004 StandoutNobel
The alpha(2a)-adrenergic receptor plays a protective role in mouse behavioral models of depression and anxiety.
2001
Cardiac Overexpression of a G q Inhibitor Blocks Induction of Extracellular Signal–Regulated Kinase and c-Jun NH 2 -Terminal Kinase Activity in In Vivo Pressure Overload
2001
Identification of the endophilins (SH3p4/p8/p13) as novel binding partners for the β1-adrenergic receptor
1999 StandoutNobel
The PDZ-binding motif of the β 2 -adrenoceptor is essential for physiologic signaling and trafficking in cardiac myocytes
2003 StandoutNobel
INSIGHTS FROM IN VIVO MODIFICATION OF ADRENERGIC RECEPTOR GENE EXPRESSION
1998 StandoutNobel
Gene targeting — homing in on α2-adrenoceptor-subtype function
1997 StandoutNobel
Genetics of Sensory Mechanotransduction
2002 StandoutNobel
Works of Mary E. Stevens being referenced
Protease-Activated Receptor 2 Mediates Eosinophil Infiltration and Hyperreactivity in Allergic Inflammation of the Airway
2002
A YAC Mouse Model for Huntington’s Disease with Full-Length Mutant Huntingtin, Cytoplasmic Toxicity, and Selective Striatal Neurodegeneration
1999
Lethal α–thalassaemia created by gene targeting in mice and its genetic rescue
1995
X Chromosome Inactivation Is Initiated in Human Preimplantation Embryos
2009
Functional screening of an asthma QTL in YAC transgenic mice
1999
Chimeric homeobox gene E2A-PBX1 induces proliferation, apoptosis, and malignant lymphomas in transgenic mice
1993
Overexpression of angiotensin AT 1 receptor transgene in the mouse myocardium produces a lethal phenotype associated with myocyte hyperplasia and heart block
1997 StandoutNobel
Cardiovascular Regulation in Mice Lacking α 2 -Adrenergic Receptor Subtypes b and c
1996 StandoutScienceNobel
Developmental and adult phenotyping directly from mutant embryonic stem cells
2007
Targeted disruption of the mouse beta1-adrenergic receptor gene: developmental and cardiovascular effects.
1996 StandoutNobel
Expression and transgenic studies of the mouse agouti gene provide insight into the mechanisms by which mammalian coat color patterns are generated
1995
Apolipoprotein B RNA editing enzyme-deficient mice are viable despite alterations in lipoprotein metabolism.
1996
Stomatocytosis Is Absent in “Stomatin”-Deficient Murine Red Blood Cells
1999
Disruption of positional fields in apterous imaginal discs of Drosophila
1986
Pleiotropic effects of the mouse lethal yellow (A y) mutation explained by deletion of a maternally expressed gene and the simultaneous production of agouti fusion RNAs
1994
Targeted α1A-Adrenergic Receptor Overexpression Induces Enhanced Cardiac Contractility but not Hypertrophy
2001