Citation Impact
Citing Papers
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
2019 StandoutScienceNobel
Brd4 Coactivates Transcriptional Activation of NF-κB via Specific Binding to Acetylated RelA
2008
Induction of interferon-stimulated gene expression and antiviral responses require protein deacetylase activity
2004 StandoutNobel
Computational design of soluble and functional membrane protein analogues
2024 StandoutNatureNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
Activation of Store-Operated Ca2+ Current in Xenopus Oocytes Requires SNAP-25 but Not a Diffusible Messenger
1999 StandoutNobel
Activation of p53 Sequence-Specific DNA Binding by Acetylation of the p53 C-Terminal Domain
1997 Standout
Manipulation of cell surface macromolecules by flaviviruses
2003
Angiopoietin-like protein 4: health effects, modulating agents and structure–function relationships
2012
β-catenin interacts with and inhibits NF-κB in human colon and breast cancer
2002
Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration
1995 StandoutNobel
Enhanced angiogenesis in obesity and in response to PPARγ activators through adipocyte VEGF and ANGPTL4 production
2008
Interleukin-17 Family Members and Inflammation
2004 Standout
Interferon Regulatory Factor-3-mediated Activation of the Interferon-sensitive Response Element by Toll-like receptor (TLR) 4 but Not TLR3 Requires the p65 Subunit of NF-κ
2003
The Role of Angiopoietin-Like Proteins in Angiogenesis and Metabolism
2008
The Non-ankyrin C Terminus of IκBα Physically Interacts with p53 in Vivo and Dissociates in Response to Apoptotic Stress, Hypoxia, DNA Damage, and Transforming Growth Factor-β1-mediated Growth Suppression
2002
The cancer glycocalyx mechanically primes integrin-mediated growth and survival
2014 StandoutNatureNobel
Twenty-Five Years of the Nucleosome, Fundamental Particle of the Eukaryote Chromosome
1999 StandoutNobel
Heme oxygenase-1: function, regulation, and implication of a novel stress-inducible protein in oxidant-induced lung injury.
1996 Standout
Nuclear Role of IκB Kinase-γ/NF-κB Essential Modulator (IKKγ/NEMO) in NF-κB-dependent Gene Expression
2004
Regulation of NF-κB RelA Phosphorylation and Transcriptional Activity by p21 and Protein Kinase Cζ in Primary Endothelial Cells
1999
Characterization of a primate model of asthma using anti-allergy/ anti-asthma agents
1996
CRISPR-Cas9 Circular Permutants as Programmable Scaffolds for Genome Modification
2019 StandoutNobel
Virus Infection Leads to Localized Hyperacetylation of Histones H3 and H4 at the IFN-β Promoter
1999
Histone H3 phosphorylation by IKK-α is critical for cytokine-induced gene expression
2003 Nature
Highly efficient Cas9-mediated transcriptional programming
2015
Pregnancy Maintenance and Parturition: The Role of Prostaglandin in Manipulating the Immune and Inflammatory Response
1994
Increased matrix metalloproteinase-9 concentration and activity after stimulation with interleukin-17 in mouse airways
2004
Molecular Determinants of Crosstalk between Nuclear Receptors and Toll-like Receptors
2005
Nuclear Factor-κB Modulates the p53 Response in Neurons Exposed to DNA Damage
2004
Visualizing the mechanical activation of Src
2005 StandoutNatureNobel
Regulation of Chemokine Expression by Antiinflammatory Cytokines
2002
Missing Pieces in the NF-κB Puzzle
2002 Standout
Composite co-activator ARC mediates chromatin-directed transcriptional activation
1999 Nature
Epidermal Growth Factor Activates Hyaluronan Synthase 2 in Epidermal Keratinocytes and Increases Pericellular and Intracellular Hyaluronan
2001
Intrinsic Immunity Shapes Viral Resistance of Stem Cells
2017 StandoutNobel
Inhibition of the RelA(p65) NF-κB Subunit by Egr-1
2000
The Effects of Hemodynamic Force on Embryonic Development
2010
Phosphorylation of NF-κB p65 by PKA Stimulates Transcriptional Activity by Promoting a Novel Bivalent Interaction with the Coactivator CBP/p300
1998
Transmembrane Pickets Connect Cyto- and Pericellular Skeletons Forming Barriers to Receptor Engagement
2018 StandoutNobel
Induction of interleukin-8 preserves the angiogenic response in HIF-1α–deficient colon cancer cells
2005
Suppression of inflammation by a synthetic histone mimic
2010 StandoutNatureNobel
Capacitative calcium entry is inhibited in vascular endothelial cells by disruption of cytoskeletal microfilaments
1997
Rho signaling and mechanical control of vascular development
2008
Atherosclerosis — An Inflammatory Disease
1999 Standout
Met, metastasis, motility and more
2003 Standout
Regulation of Expression of the Human Monocyte Chemotactic Protein-1 Receptor (hCCR2) by Cytokines
1997
Nuclear receptors versus inflammation: mechanisms of transrepression
2006
Long-term Pharmacological Activation of PPARγDoes not Prevent Left Ventricular Remodeling in Dogs with Advanced Heart Failure
2007
Recruitment of CBP/p300 by the IFNβ Enhanceosome Is Required for Synergistic Activation of Transcription
1998
Evidence for Pro-angiogenic Functions of VEGF-Ax
2016
Modulation of NF‐κB‐dependent transcription and cell survival by the SIRT1 deacetylase
2004 Standout
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
Virus Infection Induces the Assembly of Coordinately Activated Transcription Factors on the IFN-β Enhancer In Vivo
1998
Cancer-related inflammation
2008 StandoutNature
Regulation of growth factor signaling and cell cycle progression by cell adhesion and adhesion-dependent changes in cellular tension
2005
VEGF in Signaling and Disease: Beyond Discovery and Development
2019 Standout
TAK-242 (Resatorvid), a Small-Molecule Inhibitor of Toll-Like Receptor (TLR) 4 Signaling, Binds Selectively to TLR4 and Interferes with Interactions between TLR4 and Its Adaptor Molecules
2010
Cancer Dissemination—Lessons from Leukocytes
2010
INK4 cell cycle inhibitors direct transcriptional inactivation of NF-κB
1999
Integrating cell-signalling pathways with NF-κB and IKK function
2006 Standout
The Tumor Necrosis Factor Ligand and Receptor Families
1996 StandoutNobel
Role of Endothelial Cell Metabolism in Vessel Sprouting
2013
Click Chemistry for Drug Development and Diverse Chemical–Biology Applications
2013 Standout
Structural organization of yeast and mammalian mediator complexes
2000 StandoutNobel
β-Arrestin inhibits NF-κB activity by means of its interaction with the NF-κB inhibitor IκBα
2004 StandoutNobel
Digoxin and other cardiac glycosides inhibit HIF-1α synthesis and block tumor growth
2008 StandoutNobel
Heterogeneity of Endothelial Cells
1997
Glucocorticoid Receptor Recruitment of Histone Deacetylase 2 Inhibits Interleukin-1β-Induced Histone H4 Acetylation on Lysines 8 and 12
2000
Regulation of nuclear factor kappaB activation by G-protein-coupled receptors.
2001
IκB Kinase α-Mediated Derepression of SMRT Potentiates Acetylation of RelA/p65 by p300
2005
Proline Rich Motifs as Drug Targets in Immune Mediated Disorders
2012
Global gene expression of cells attached to a tissue engineering scaffold
2004 StandoutNobel
Constitutive Activation of Toll-Mediated Antifungal Defense in Serpin-Deficient Drosophila
1999 StandoutScienceNobel
Mutant Cells That Do Not Respond to Interleukin-1 (IL-1) Reveal a Novel Role for IL-1 Receptor-Associated Kinase
1999
Myocardial Fatty Acid Metabolism in Health and Disease
2010 Standout
B7x: A widely expressed B7 family member that inhibits T cell activation
2003 StandoutNobel
Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator Activity by IκB Kinase
2002
Expression and regulation of the PD-L1 immunoinhibitory molecule on microvascular endothelial cells.
2002
Hypoxia-inducible Factor-1 Mediates Transcriptional Activation of the Heme Oxygenase-1 Gene in Response to Hypoxia
1997 StandoutNobel
Mechanism of Rapid Transcriptional Induction of Tumor Necrosis Factor Alpha-Responsive Genes by NF-κB
2002
Expression and Regulation of the PD-L1 Immunoinhibitory Molecule on Microvascular Endothelial Cells
2002
Posttranslational hydroxylation of ankyrin repeats in IκB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH)
2006 StandoutNobel
Inhibition of angiogenesis and vascular leakiness by angiopoietin-related protein 4.
2003
Crystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protection
2011 StandoutNobel
Making the cut: Protease-mediated regulation of angiogenesis
2006
TNF-α inhibits asbestos-induced cytotoxicity via a NF-κB-dependent pathway, a possible mechanism for asbestos-induced oncogenesis
2006
Essential roles of tumor necrosis factor receptor p55 in liver metastasis of intrasplenic administration of colon 26 cells.
2002
Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment
2018 StandoutNobel
Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2
1997 StandoutNobel
Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1
2004 StandoutNobel
HIF‐dependent induction of adenosine A2B receptor in hypoxia
2006
Lipopolysaccharide Activation of the TPL-2/MEK/Extracellular Signal-Regulated Kinase Mitogen-Activated Protein Kinase Cascade Is Regulated by IκB Kinase-Induced Proteolysis of NF-κB1 p105
2004
The p65 (RelA) Subunit of NF-κB Interacts with the Histone Deacetylase (HDAC) Corepressors HDAC1 and HDAC2 To Negatively Regulate Gene Expression
2001
Tensegrity II. How structural networks influence cellular information processing networks
2003
Transcriptional Activation by NF-κB Requires Multiple Coactivators
1999
Piezo1, a mechanically activated ion channel, is required for vascular development in mice
2014 StandoutNobel
Hypoxia induces macrophage inflammatory protein‐2 (MIP‐2) gene expression in murine macrophages via NF‐κB: the prominent role of p42/ p44 and PI3 kinase pathways
2004
PD-L1 and PD-L2 are differentially regulated by Th1 and Th2 cells
2003 StandoutNobel
How Do Glucocorticoids Influence Stress Responses? Integrating Permissive, Suppressive, Stimulatory, and Preparative Actions*
2000 Standout
NF-κB AND REL PROTEINS: Evolutionarily Conserved Mediators of Immune Responses
1998 Standout
Multistage nanoparticle delivery system for deep penetration into tumor tissue
2011 StandoutNobel
Phase II Trial of Infusional Fluorouracil, Irinotecan, and Bevacizumab for Metastatic Colorectal Cancer: Efficacy and Circulating Angiogenic Biomarkers Associated With Therapeutic Resistance
2009
Mechanisms of Diabetic Complications
2013 Standout
Transcriptional Cross Talk between NF-κB and p53
1999
Regulation of nuclear factor κB activation by G-protein-coupled receptors
2001
O2 Regulates Skeletal Muscle Progenitor Differentiation through Phosphatidylinositol 3-Kinase/AKT Signaling
2011
Hypoxic retinal Müller cells promote vascular permeability by HIF-1–dependent up-regulation of angiopoietin-like 4
2013 StandoutNobel
Angiogenesis in Endocrine Tumors
2003
Signaling and Functions of Angiopoietin-1 in Vascular Protection
2006
Top-down design of protein architectures with reinforcement learning
2023 StandoutScienceNobel
Transcriptional Coregulators in Development
1999 Science
Hypoxia-inducible factor 1 is required for remote ischemic preconditioning of the heart
2013 StandoutNobel
The Interplay between the Glucocorticoid Receptor and Nuclear Factor-κB or Activator Protein-1: Molecular Mechanisms for Gene Repression
2003
Regulation of Wound Healing by Growth Factors and Cytokines
2003 Standout
Differential effects of exercise on insulin-signaling gene expression in human skeletal muscle
2001
Morphogen gradient interpretation
2001 StandoutNatureNobel
Angiogenesis.
1992 Standout
Works of Mary E. Gerritsen being referenced
Regulation of Endothelial Cell Proliferation and Apoptosis by Cyclic Pressure
2002
Glucose starvation is required for insulin stimulation of glucose uptake and metabolism in cultured microvascular endothelial cells
1988
A Novel Interleukin-17 Receptor-like Protein Identified in Human Umbilical Vein Endothelial Cells Antagonizes Basic Fibroblast Growth Factor-induced Signaling
2003
Hepatocyte Growth Factor Enhances Vascular Endothelial Growth Factor-Induced Angiogenesis in Vitro and in Vivo
2001
Nuclear Integration of Glucocorticoid Receptor and Nuclear Factor-κB Signaling by CREB-binding Protein and Steroid Receptor Coactivator-1
1998
Peroxisome Proliferator-activated Receptor γ Ligands Are Potent Inhibitors of Angiogenesis in Vitro and in Vivo
1999
Receptor-selective Variants of Human Vascular Endothelial Growth Factor
2000
12(R)-hydroxyeicosatrienoic acid, a potent chemotactic and angiogenic factor produced by the cornea
1991
Novel Inhibitors of Cytokine-induced IκBα Phosphorylation and Endothelial Cell Adhesion Molecule Expression Show Anti-inflammatory Effects in Vivo
1997
Using gene expression profiling to identify the molecular basis of the synergistic actions of hepatocyte growth factor and vascular endothelial growth factor in human endothelial cells
2003
Cytokeratin Expression and Hyaluronic Acid Production in Cultures of Human Synovial Microvascular Endothelial Cells: Influence of Cytokines and Growth Factors
1996
Branching Out: A Molecular Fingerprint of Endothelial Differentiation into Tube‐Like Structures Generated by Affymetrix Oligonucleotide Arrays
2003
Endothelial Expression of Vascular Cell Adhesion Molecule‐1 Correlates with Metastatic Pattern in Spontaneous Melanoma
2001
A Dominant-Negative p65 PAK Peptide Inhibits Angiogenesis
2002
Time course of skeletal muscle repair and gene expression following acute hind limb ischemia in mice
2002
Gene Expression Profiling in an in Vitro Model of Angiogenesis
2000
Cellular signaling responses mediated by a novel nucleotide receptor in rabbit microvessel endothelium
1993
Repeated antigen inhalation results in a prolonged airway eosinophilia and airway hyperresponsiveness in primates
1990
Differential up-regulation of circulating soluble and endothelial cell intercellular adhesion molecule-1 in mice.
1997
Cytokine-induced VCAM-1 and ICAM-1 expression in different organs of the mouse.
1997
Exposure of Human Vascular Endothelial Cells to Sustained Hydrostatic Pressure Stimulates Proliferation
1999
Endothelial expression of vascular cell adhesion molecule-1 correlates with metastatic pattern in spontaneous melanoma.
2001
CREB-binding protein/p300 are transcriptional coactivators of p65
1997
Chemokine gene expression and secretion by cytokine-activated human microvascular endothelial cells. Differential regulation of monocyte chemoattractant protein-1 and interleukin-8 in response to interferon-gamma.
1994
Endothelial-dependent Mechanisms Regulate Leukocyte Transmigration: A Process Involving the Proteasome and Disruption of the Vascular Endothelial–Cadherin Complex at Endothelial Cell-to-Cell Junctions
1997
Targeting Protein Kinases for Cancer Therapy
2010
Altered proliferation of retinal microvascular cells on glycated matrix.
1995
Transfection of the human heme oxygenase gene into rabbit coronary microvessel endothelial cells: protective effect against heme and hemoglobin toxicity.
1995
VEGF-C mediates cyclic pressure-induced endothelial cell proliferation
2002
Arachidonic acid and prostaglandin endoperoxide metabolism in isolated rabbit and coronary microvessels and isolated and cultivated coronary microvessel endothelial cells.
1983
Vascular Endothelial Growth Factor–Induced Genes in Human Umbilical Vein Endothelial Cells
2002