Standout Papers
- Mutation in the Phosphorylation Sites of MAP Kinase Blocks Learning-Related Internalization of apCAM in Aplysia Sensory Neurons (1997)
- A Transient, Neuron-Wide Form of CREB-Mediated Long-Term Facilitation Can Be Stabilized at Specific Synapses by Local Protein Synthesis (1999)
- Serotonin-Mediated Endocytosis of apCAM: an Early Step of Learning-Related Synaptic Growth in Aplysia (1992)
- Aplysia CREB2 represses long-term facilitation: Relief of repression converts transient facilitation into long-term functional and structural change (1995)
- Inhibitors of protein and RNA synthesis block structural changes that accompany long-term heterosynaptic plasticity in Aplysia (1992)
- Synapse-Specific, Long-Term Facilitation of Aplysia Sensory to Motor Synapses: A Function for Local Protein Synthesis in Memory Storage (1997)
- 5-HT and cAMP induce the formation of coated pits and vesicles and increase the expression of clathrin light chain in sensory neurons of aplysia (1993)
- A novel function for serotonin-mediated short-term facilitation in Aplysia : Conversion of a transient, cell-wide homosynaptic Hebbian plasticity into a persistent, protein synthesis-independent synapse-specific enhancement (2000)
- Tissue Plasminogen Activator Contributes to the Late Phase of LTP and to Synaptic Growth in the Hippocampal Mossy Fiber Pathway (1998)
Citation Impact
Citing Papers
TOR Signaling in Growth and Metabolism
2006 Standout
Dynamic Visualization of Local Protein Synthesis in Hippocampal Neurons
2001
Cross Talk between ERK and PKA Is Required for Ca2+ Stimulation of CREB-Dependent Transcription and ERK Nuclear Translocation
1998
Cell Adhesion Molecules, CREB, and the Formation of New Synaptic Connections
1996 StandoutNobel
MicroRNAs
2004 Standout
Induction of CRE-Mediated Gene Expression by Stimuli That Generate Long-Lasting LTP in Area CA1 of the Hippocampus
1996
Local synthesis of nuclear‐encoded mitochondrial proteins in the presynaptic nerve terminal
2001
A Molecular Switch for the Consolidation of Long‐Term Memory: cAMP‐Inducible Gene Expression
1995 StandoutNobel
A role for the neural cell adhesion molecule in a late, consolidating phase of glycoprotein synthesis six hours following passive avoidance training of the young chick
1993
Target-dependent structural changes in sensory neurons of aplysia accompany long-term heterosynaptic inhibition
1991
Fear memories require protein synthesis in the amygdala for reconsolidation after retrieval
2000 StandoutNature
5-HT modulates protein synthesis and the expression of specific proteins during long-term facilitation in aplysia sensory neurons
1989 StandoutNobel
Serotonin Induces Temporally and Mechanistically Distinct Phases of Persistent PKA Activity in Aplysia Sensory Neurons
1998
Genetic Dissection of Structural and Functional Components of Synaptic Plasticity. III. CREB Is Necessary for Presynaptic Functional Plasticity
1996
Nerve-terminal proteins: to fuse to learn
1994
Rab proteins and the road maps for intracellular transport
1993
Inducible and Reversible Enhancement of Learning, Memory, and Long-Term Potentiation by Genetic Inhibition of Calcineurin
2001 Nobel
Synaptic restructuring during long-term facilitation at the crayfish neuromuscular junction
1989
Long-Term sensitization training in Aplysia leads to an increase in calreticulin, a major presynaptic calcium-binding protein
1992 StandoutNobel
Impulse activity and the patterning of connections during cns development
1990
Genetic and Pharmacological Evidence for a Novel, Intermediate Phase of Long-Term Potentiation Suppressed by Calcineurin
1998 StandoutNobel
Molecular Enhancement of Memory Formation
1996
Synaptic transmission: A bidirectional and self-modifiable form of cell-cell communication
1993 StandoutNobel
Neurotransmitters in the regulation of neuronal cytoarchitecture
1988
Chemotropic Responses of Retinal Growth Cones Mediated by Rapid Local Protein Synthesis and Degradation
2001
Mechanisms for Generating the Autonomous cAMP-Dependent Protein Kinase Required for Long-Term Facilitation in Aplysia
1999 StandoutNobel
A single population of olfactory sensory neurons mediates an innate avoidance behaviour in Drosophila
2004 StandoutNatureNobel
Enhancement of Memory-Related Long-Term Facilitation by ApAF, a Novel Transcription Factor that Acts Downstream from Both CREB1 and CREB2
2000 StandoutNobel
cAMP and arachidonic acid simulate long-term structural and functional changes produced by neurotransmitters in aplysia sensory neurons
1993 StandoutNobel
Food and metabolic signalling defects in a Caenorhabditis elegans serotonin-synthesis mutant
2000 StandoutNatureNobel
Localized Synaptic Potentiation by BDNF Requires Local Protein Synthesis in the Developing Axon
2002
The CaM kinase II hypothesis for the storage of synaptic memory
1994
Spaced training induces normal long-term memory in CREB mutant mice
1997
Genetic approaches to memory storage
1999
Structural Changes Accompanying Memory Storage
1993 StandoutNobel
Ubiquitin C-Terminal Hydrolase Is an Immediate-Early Gene Essential for Long-Term Facilitation in Aplysia
1997 StandoutNobel
cAMP induces long-term morphological changes in sensory neurons ofAplysia
1991
Retrograde amnesia and memory consolidation: a neurobiological perspective
1995
A novel intermediate stage in the transition between short- and long-term facilitation in the sensory to motor neuron synapse of aplysia
1995 StandoutNobel
Neuronal RNA Granules
2001
A quantitative analysis of 2-D gels identifies proteins in which labeling is increased following long-term sensitization in Aplysia
1988 StandoutNobel
CREB and the formation of long-term memory
1996
Local protein synthesis and its role in synapse-specific plasticity
2000 StandoutNobel
Synaptic tagging — who's it?
2002
The power of the 3′ UTR: translational control and development
2003
Genetic Dissection of Structural and Functional Components of Synaptic Plasticity. I. Fasciclin II Controls Synaptic Stabilization and Growth
1996
CREB1 Encodes a Nuclear Activator, a Repressor, and a Cytoplasmic Modulator that Form a Regulatory Unit Critical for Long-Term Facilitation
1998 StandoutNobel
C/EBP is an immediate-early gene required for the consolidation of long-term facilitation in Aplysia
1994 StandoutNobel
Injection of the cAMP-responsive element into the nucleus of Aplysia sensory neurons blocks long-term facilitation
1990 StandoutNatureNobel
CREB Phosphorylation and Dephosphorylation: A Ca2+- and Stimulus Duration–Dependent Switch for Hippocampal Gene Expression
1996
Stimulation of cAMP response element (CRE)-mediated transcription during contextual learning
1998
Activation of cAMP-Responsive genes by stimuli that produce long-term facilitation in aplysia sensory neurons
1993 StandoutNobel
Synaptic Clustering of the Cell Adhesion Molecule Fasciclin II by Discs-Large and its Role in the Regulation of Presynaptic Structure
1997
Cyclic AMP induces functional presynaptic boutons in hippocampal CA3–CA1 neuronal cultures
1999
Cognitive Neuroscience and the Study of Memory
1998
Inhibitor of protein synthesis blocks longterm behavioral sensitization in the isolated gill‐withdrawal reflex of Aplysia
1989 StandoutNobel
The role of Rab3A in neurotransmitter release
1994 StandoutNatureNobel
Genetic Dissection of Structural and Functional Components of Synaptic Plasticity. II. Fasciclin II Controls Presynaptic Structural Plasticity
1996
The synaptic vesicle cycle: a cascade of protein–protein interactions
1995 StandoutNatureNobel
Developmental mechanisms that generate precise patterns of neuronal connectivity
1993
α-Neurexins couple Ca2+ channels to synaptic vesicle exocytosis
2003 StandoutNatureNobel
MAP Kinase Translocates into the Nucleus of the Presynaptic Cell and Is Required for Long-Term Facilitation in Aplysia
1997 StandoutNobel
Rolipram, a type IV-specific phosphodiesterase inhibitor, facilitates the establishment of long-lasting long-term potentiation and improves memory
1998 StandoutNobel
Long-term structural remodeling in Aplysia sensory neurons requires de novo protein synthesis during a critical time period
1995
The long and the short of long–term memory—a molecular framework
1986 StandoutNatureNobel
Serotonin Activates S6 Kinase in a Rapamycin-Sensitive Manner inAplysiaSynaptosomes
2001
A Critical Period for Macromolecular Synthesis in Long-Term Heterosynaptic Facilitation in Aplysia
1986 Science
Capture of a protein synthesis-dependent component of long-term depression
2000 StandoutNobel
cAMP Response Element-Binding Protein in the Amygdala Is Required for Long- but not Short-Term Conditioned Taste Aversion Memory
1997
Is there a cell-biological alphabet for simple forms of learning?
1984 StandoutNobel
Aplysia cell adhesion molecules and serotonin regulate sensory cell- motor cell interactions during early stages of synapse formation in vitro
1994
Long-term memory in Aplysia modulates the total number of varicosities of single identified sensory neurons.
1988
Learning Performance of Normal and MutantDrosophilaafter Repeated Conditioning Trials with Discrete Stimuli
2000
Sensitization of the gill and siphon withdrawal reflex of Aplysia: multiple sites of change in the neuronal network
1993
Monosynaptic connections made by the sensory neurons of the gill- and siphon-withdrawal reflex in Aplysia participate in the storage of long-term memory for sensitization
1985 StandoutNobel
Memory Suppressor Genes: Inhibitory Constraints on the Storage of Long-Term Memory
1998 StandoutScienceNobel
Tracking the flow of learned information from membrane receptors to genome
1986 StandoutNobel
Time course of structural changes at identified sensory neuron synapses during long-term sensitization in Aplysia
1989
Requirement of a Critical Period of Transcription for Induction of a Late Phase of LTP
1994 StandoutScienceNobel
Long-term expansion and sensitization of mechanosensory receptive fields in Aplysia support an activity-dependent model of whole-cell sensory plasticity
1989
Neural cell adhesion molecules in activity-dependent development and synaptic plasticity
1996
Long-Term Facilitation in Aplysia Involves Increase in Transmitter Release
1988 Science
Induction of long-term facilitation in Aplysia sensory neurons by local application of serotonin to remote synapses.
1993 StandoutNobel
Protein Synthesis at Synaptic Sites on Dendrites
2001
Long-term sensitization training in Aplysia leads to an increase in the expression of BiP, the major protein chaperon of the ER.
1992 StandoutNobel
cAMP Evokes Long-Term Facilitation in Aplysia Sensory Neurons That Requires New Protein Synthesis
1988 Science
Neural Science
2000 StandoutNobel
CREB AND MEMORY
1998
Long-term sensitization in Aplysia increases the number of presynaptic contacts onto the identified gill motor neuron L7.
1988
Antisense oligodeoxynucleotide-mediated disruption of hippocampal cAMP response element binding protein levels impairs consolidation of memory for water maze training
1997
Deficits in Memory Tasks of Mice with CREB Mutations Depend on Gene Dosage
1998
Control of Memory Formation Through Regulated Expression of a CaMKII Transgene
1996 StandoutScienceNobel
Are Adult Learning Mechanisms Also Used for Development?
1992 StandoutScienceNobel
Selective short- and long-term effects of serotonin, small cardioactive peptide, and tetanic stimulation on sensorimotor synapses of Aplysia in culture
1990
Role of Transforming Growth Factor-β in Long-Term Synaptic Facilitation in Aplysia
1997 Science
An Unbiased cDNA Library Prepared from IsolatedAplysiaSensory Neuron Processes Is Enriched for Cytoskeletal and Translational mRNAs
2003 StandoutNobel
Serotonin activates S6 kinase in a rapamycin-sensitive manner in Aplysia synaptosomes.
2001
Protein Sorting by Transport Vesicles
1996 StandoutScienceNobel
A Simplified Preparation for Relating Cellular Events to Behavior: Mechanisms Contributing to Habituation, Dishabituation, and Sensitization of theAplysiaGill-Withdrawal Reflex
1997 StandoutNobel
Repeated pulses of serotonin required for long-term facilitation activate mitogen-activated protein kinase in sensory neurons of Aplysia
1998 StandoutNobel
The anatomy of a memory: convergence of results across a diversity of tests
1988
A Functional Role for Intra-Axonal Protein Synthesis during Axonal Regeneration from Adult Sensory Neurons
2001
Synthesis and functional integration of a neurotransmitter receptor in isolated invertebrate axons
2000
Intracellular Injection of cAMP Induces a Long-Term Reduction of Neuronal K + Currents
1988 Science
The Molecular Biology of Memory Storage: A Dialogue Between Genes and Synapses
2001 StandoutScienceNobel
GENE DISCOVERY INDROSOPHILA: New Insights for Learning and Memory
1998
Toward a molecular definition of long-term memory storage
1996 StandoutNobel
Memory Consolidation for Contextual and Auditory Fear Conditioning Is Dependent on Protein Synthesis, PKA, and MAP Kinase
1999
Target-Dependent Structural Changes Accompanying Long-Term Synaptic Facilitation in Aplysia Neurons
1990 StandoutScienceNobel
Morphological transformation of synaptic terminals of a phasic motoneuron by long-term tonic stimulation
1986
GENE TARGETING AND THE BIOLOGY OF LEARNING AND MEMORY
1997
Synaptic Assembly of the Brain in the Absence of Neurotransmitter Secretion
2000 StandoutScienceNobel
Long-Term Synaptic Facilitation in the Absence of Short-Term Facilitation in Aplysia Neurons
1993 Science
Long-lasting forms of synaptic potentiation in the mammalian hippocampus.
1996
A Macromolecular Synthesis-Dependent Late Phase of Long-Term Potentiation Requiring cAMP in the Medial Perforant Pathway of Rat Hippocampal Slices
1996 StandoutNobel
Long-Term Sensitization in Aplysia : Biophysical Correlates in Tail Sensory Neurons
1987 Science
Serotonin increases intracellular Ca2+ transients in voltage-clamped sensory neurons of Aplysia californica.
1984 StandoutNobel
Spatial Representation in the Entorhinal Cortex
2004 StandoutScienceNobel
Both Protein Kinase A and Mitogen-Activated Protein Kinase Are Required in the Amygdala for the Macromolecular Synthesis-Dependent Late Phase of Long-Term Potentiation
2000 StandoutNobel
SynCAM, a Synaptic Adhesion Molecule That Drives Synapse Assembly
2002 StandoutScienceNobel
Modulation of an NCAM-Related Adhesion Molecule with Long-Term Synaptic Plasticity in Aplysia
1992 StandoutScienceNobel
Works of Mary Chen being referenced
Structural plasticity at identified synapses during long‐term memory in Aplysia
1989
5-HT and cAMP induce the formation of coated pits and vesicles and increase the expression of clathrin light chain in sensory neurons of aplysia
1993 StandoutNobel
Morphological Aspects of Synaptic Plasticity in Aplysia An Anatomical Substrate for Long‐Term Memorya
1991
Aplysia CREB2 represses long-term facilitation: Relief of repression converts transient facilitation into long-term functional and structural change
1995 StandoutNobel
Synapse-Specific, Long-Term Facilitation of Aplysia Sensory to Motor Synapses: A Function for Local Protein Synthesis in Memory Storage
1997 StandoutNobel
Inhibitors of protein and RNA synthesis block structural changes that accompany long-term heterosynaptic plasticity in Aplysia
1992 StandoutNobel
A Transient, Neuron-Wide Form of CREB-Mediated Long-Term Facilitation Can Be Stabilized at Specific Synapses by Local Protein Synthesis
1999 StandoutNobel
Mutation in the Phosphorylation Sites of MAP Kinase Blocks Learning-Related Internalization of apCAM in Aplysia Sensory Neurons
1997 StandoutNobel
Serotonin-Mediated Endocytosis of apCAM: an Early Step of Learning-Related Synaptic Growth in Aplysia
1992 StandoutScienceNobel
Morphological Basis of Long-Term Habituation and Sensitization in Aplysia
1983 Science