Citation Impact
Citing Papers
Mucosal healing in inflammatory bowel diseases: a systematic review
2012 Standout
Hydrogen sulfide mediates the vasoactivity of garlic
2007 Standout
CYP2A6: genetics, structure, regulation, and function
2012
TEER Measurement Techniques for In Vitro Barrier Model Systems
2015 Standout
Multidrug resistance in cancer: role of ATP–dependent transporters
2002 Standout
Nicotine Chemistry, Metabolism, Kinetics and Biomarkers
2009 Standout
Induction of Human UDP Glucuronosyltransferases (UGT1A6, UGT1A9, and UGT2B7) by t-Butylhydroquinone and 2,3,7,8-Tetrachlorodibenzo-p-Dioxin in Caco-2 Cells
1999
Predicting Oral Absorption and Bioavailability
2003
Pharmacology and Management of the Vitamin K Antagonists
2008 Standout
A Systematic Comparison of the Properties of Clinically Used Angiotensin II Type 1 Receptor Antagonists
2013
Quinolines and structurally related heterocycles as antimalarials
2010 Standout
The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins
2008 StandoutNature
Therapeutic potential of resveratrol: the in vivo evidence
2006 Standout
The influence of drug-like concepts on decision-making in medicinal chemistry
2007 Standout
Effects of the Antifungal Agents on Oxidative Drug Metabolism
2000
Inhibition of Cytochromes P450 by Antifungal Imidazole Derivatives
2002
Clinical Pharmacogenetics Implementation Consortium Guidelines for CYP2C19 Genotype and Clopidogrel Therapy: 2013 Update
2013 Standout
OXIDATIVE METABOLISM OF THE ALKALOID RUTAECARPINE BY HUMAN CYTOCHROME P450
2006
CYP2A6: a human coumarin 7-hydroxylase
2000
Polymorphism of human cytochrome P450 enzymes and its clinical impact
2009
Importance of disrupted intestinal barrier in inflammatory bowel diseases
2010
Natural products: An evolving role in future drug discovery
2011 Standout
INTERACTIONS OF TWO MAJOR METABOLITES OF PRASUGREL, A THIENOPYRIDINE ANTIPLATELET AGENT, WITH THE CYTOCHROMES P450
2006
Lead- and drug-like compounds: the rule-of-five revolution
2004 Standout
Cytochrome P450 reaction-phenotyping: an industrial perspective
2007
Mechanisms of action of hydroxychloroquine and chloroquine: implications for rheumatology
2020 Standout
Structure and function of the blood–brain barrier
2009 Standout
Cytochrome P-450 Polymorphisms and Response to Clopidogrel
2008 Standout
Effects of Prototypical Microsomal Enzyme Inducers on Cytochrome P450 Expression in Cultured Human Hepatocytes
2003
In Vitro Permeability Across Caco-2 Cells (Colonic) Can Predict In Vivo (Small Intestinal) Absorption in Man—Fact or Myth
1997
Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings 1PII of original article: S0169-409X(96)00423-1. The article was originally published in Advanced Drug Delivery Reviews 23 (1997) 3–25. 1
2001 Standout
New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays
2010 Standout
Cytochrome P450 2C9 polymorphisms: a comprehensive review of the in-vitro and human data
2002
VALIDATED ASSAYS FOR HUMAN CYTOCHROME P450 ACTIVITIES
2004
Caco-2 permeability, P-glycoprotein transport ratios and brain penetration of heterocyclic drugs
2003
Effects of chlorophyllin on transport of dibenzo(a, l)pyrene, 2-amino-1-methyl-6-phenylimidazo-[4,5-b]pyridine, and aflatoxin B1 across Caco-2 cell monolayers
2004
In vitro systems for studying intestinal drug absorption
1995
Natural products to drugs: natural product-derived compounds in clinical trials
2008 Standout
Allergic Rhinitis and Its Impact on Asthma
2001 Standout
Metabolism and Disposition Kinetics of Nicotine
2005
Molecular Genetics of Nicotine Metabolism
2009
Applicability of an in vitro digestion model in assessing the bioaccessibility of mycotoxins from food
2004 Standout
Functional pharmacogenetics/genomics of human cytochromes P450 involved in drug biotransformation
2008
Current methodologies used for evaluation of intestinal permeability and absorption
2000
Quinoline, quinazoline and acridonealkaloids
2007 Standout
Bioorganometallic chemistry—from teaching paradigms to medicinal applications
2008 Standout
Hepatic metabolism of diallyl disulphide in rat and man
2003
Ferrocene Conjugates of Chloroquine and other Antimalarials: the Development of Ferroquine, a New Antimalarial
2007
Three haplotypes associated with CYP2A6 phenotypes in Caucasians
2005
Diversity of selective environmental substrates for human cytochrome P450 2A6: alkoxyethers, nicotine, coumarin, N-nitrosodiethylamine, and N-nitrosobenzylmethylamine
2003
Down-Regulation of Hepatic Nicotine Metabolism and a CYP2A6-Like Enzyme in African Green Monkeys after Long-Term Nicotine Administration
2003
Structure, function, regulation and polymorphism and the clinical significance of human cytochrome P450 1A2
2009
A Simple Enantioconvergent and Chemoenzymatic Synthesis of Optically Active α‐Substituted Amides
2011 StandoutNobel
Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels
2013 StandoutNobel
Primary Hepatocytes: Current Understanding of the Regulation of Metabolic Enzymes and Transporter Proteins, and Pharmaceutical Practice for the Use of Hepatocytes in Metabolism, Enzyme Induction, Transporter, Clearance, and Hepatotoxicity Studies
2007
Pharmacogenetics of Warfarin Elimination and its Clinical Implications
2001
Cytochrome P450 2C8 and CYP3A4/5 are involved in chloroquine metabolism in human liver microsomes
2003
The human intestinal epithelial cell line Caco-2; pharmacological and pharmacokinetic applications
1995
The Pharmacology and Management of the Vitamin K Antagonists
2004 Standout
Cytochrome P450 ω-Hydroxylase Pathway of Tocopherol Catabolism
2002 Standout
Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation
2013 Standout
PharmGKB summary
2011
Inhibition and induction of human cytochrome P450 (CYP) enzymes
1998
Organic Azides: An Exploding Diversity of a Unique Class of Compounds
2005 Standout
Ultraviolet-B Exposure of Human Skin Induces Cytochromes P450 1A1 and 1B1
2000
Assessment of specificity of eight chemical inhibitors using cDNA-expressed cytochromes P450
2000
Rifampin Is a Selective, Pleiotropic Inducer of Drug Metabolism Genes in Human Hepatocytes: Studies with cDNA and Oligonucleotide Expression Arrays
2001
Mitochondria-Targeted Cytoprotective Peptides for Ischemia–Reperfusion Injury
2007
Azole fungicides affect mammalian steroidogenesis by inhibiting sterol 14 alpha-demethylase and aromatase.
2002 Standout
Absorption prediction from physicochemical parameters
1999
Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview
2012 Standout
Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
1997 Standout
pkCSM: Predicting Small-Molecule Pharmacokinetic and Toxicity Properties Using Graph-Based Signatures
2015 Standout
The P-glycoprotein antagonist PSC 833 increases the plasma concentrations of 6alpha-hydroxypaclitaxel, a major metabolite of paclitaxel.
2001
Analysis of the Structural Diversity, Substitution Patterns, and Frequency of Nitrogen Heterocycles among U.S. FDA Approved Pharmaceuticals
2014 Standout
Observational Study of Hydroxychloroquine in Hospitalized Patients with Covid-19
2020 Standout
Prediction of Drug Absorption Using Multivariate Statistics
2000 Standout
Organometallic Anticancer Compounds
2010 Standout
Synthesis and Porous Properties of Chromium Azolate Porous Coordination Polymers
2014 StandoutNobel
IN VITRO AND IN VIVO DRUG INTERACTIONS INVOLVING HUMAN CYP3A
1998
Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems
2014 StandoutNobel
The Many Roles for Fluorine in Medicinal Chemistry
2008 Standout
Oxadiazoles in Medicinal Chemistry
2011 Standout
<i>Trans</i>-resveratrol modulates the catalytic activity and mRNA expression of the procarcinogen-activating human cytochrome P450 1B1
2000
Design and Synthesis of Hydroxyferroquine Derivatives with Antimalarial and Antiviral Activities
2006
Practice Guidelines for the Diagnosis and Management of Aspergillosis: 2016 Update by the Infectious Diseases Society of America
2016 Standout
Species differences in N-glucuronidation.
1998
Human UDP-Glucuronosyltransferases: Metabolism, Expression, and Disease
2000 Standout
Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
2012 Standout
Pharmacogenetic testing among patients with mood and anxiety disorders is associated with decreased utilization and cost: A propensity-score matched study
2018 StandoutNobel
ADME Evaluation in Drug Discovery. 7. Prediction of Oral Absorption by Correlation and Classification
2006
Small-Molecule H-Bond Donors in Asymmetric Catalysis
2007 Standout
Functional properties of anthocyanins and betalains in plants, food, and in human nutrition
2003 Standout
In Vivo Cimetidine Inhibits Hepatic CYP2C6 and CYP2C11 but Not CYP1A1 in Adult Male Rats,
1998
Apoptotic Mechanisms After Cerebral Ischemia
2009 Standout
Formation and Antitumor Activity of PNU-159682, A Major Metabolite of Nemorubicin in Human Liver Microsomes
2005
Persistent hepatitis C virus infection in microscale primary human hepatocyte cultures
2010 StandoutNobel
Applications of the Caco-2 model in the design and development of orally active drugs: elucidation of biochemical and physical barriers posed by the intestinal epithelium
1997
Trans-resveratrol modulates the catalytic activity and mRNA expression of the procarcinogen-activating human cytochrome P450 1B1
2000
In Vitro Antiviral Activity and Projection of Optimized Dosing Design of Hydroxychloroquine for the Treatment of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
2020 Standout
Correlation of Gene Expression of Ten Drug Efflux Proteins of the ATP-Binding Cassette Transporter Family in Normal Human Jejunum and in Human Intestinal Epithelial Caco-2 Cell Monolayers
2001
Vorinostat-Like Molecules as Structural, Stereochemical, and Pharmacological Tools
2010
5‐Substituted 1H‐Tetrazoles as Carboxylic Acid Isosteres: Medicinal Chemistry and Synthetic Methods
2003 Standout
Evaluation of methoxsalen, tranylcypromine, and tryptamine as specific and selective CYP2A6 inhibitors in vitro.
2001
Works of Martine Bourrié being referenced
Cytochrome P450 isoform inhibitors as a tool for the investigation of metabolic reactions catalyzed by human liver microsomes.
1996
In vitro N-glucuronidation of SB 47436 (BMS 186295), a new AT1 nonpeptide angiotensin II receptor antagonist, by rat, monkey and human hepatic microsomal fractions.
1994
Correlation Between Oral Drug Absorption in Humans, and Apparent Drug Permeability in TC-7 Cells, A Human Epithelial Intestinal Cell Line: Comparison with the Parental Caco-2 Cell Line
1998
Expression and induction of CYP1A1/1A2, CYP2A6 and CYP3A4 in primary cultures of human hepatocytes: a 10-year follow-up
2000
IN VITRO METABOLISM OF FERROQUINE (SSR97193) IN ANIMAL AND HUMAN HEPATIC MODELS AND ANTIMALARIAL ACTIVITY OF MAJOR METABOLITES ON PLASMODIUM FALCIPARUM
2006
Characterisation of a newly isolated Caco-2 clone (TC-7), as a model of transport processes and biotransformation of drugs
1995
Regulation of cytochrome P450IA1 gene expression in a human intestinal cell line, Caco-2.
1992
Role of Cytochrome P-4502C9 in Irbesartan Oxidation by Human Liver Microsomes
1999