Citation Impact
Citing Papers
Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation
2014 StandoutScienceNobel
A checkpoint regulates the rate of progression through S phase in S. cerevisiae in Response to DNA damage
1995 StandoutNobel
Ku prevents Exo1 and Sgs1‐dependent resection of DNA ends in the absence of a functional MRX complex or Sae2
2010
Regulation of progression through the Gl phase of the cell cycle by the rum1+ gene
1994 StandoutNatureNobel
Ordering S phase and M phase in the cell cycle
1994 StandoutNobel
Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells
1992 StandoutNobel
Biochemical analysis of human Dna2
2006
Crystal Structure of a pol α Family Replication DNA Polymerase from Bacteriophage RB69
1997 StandoutNobel
Mechanism of the ATP-dependent DNA end-resection machinery from Saccharomyces cerevisiae
2010 Nature
Yeast DNA polymerases and their role at the replication fork
1995
Reduced X-Ray Resistance and Homologous Recombination Frequencies in a RAD54 Mutant of the Chicken DT40 Cell Line
1997
Xenopus DNA2 is a helicase/nuclease that is found in complexes with replication proteins And-1/Ctf4 and Mcm10 and DSB response proteins Nbs1 and ATM
2010
DNA polymerase ϵ links the DNA replication machinery to the S phase checkpoint
1995
Telomerase-Mediated Telomere Addition In Vivo Requires DNA Primase and DNA Polymerases α and δ
1999
Coupling M phase and S phase: Controls maintaining the dependence of mitosis on chromosome replication
1991 StandoutNobel
When Checkpoints Fail
1997 StandoutNobel
Building a Replisome from Interacting Pieces
1999 StandoutNobel
Involvement of p34cdc2 in establishing the dependency of S phase on mitosis
1991 StandoutNatureNobel
Mutations in the DNA ligase I gene of an individual with immunodeficiencies and cellular hypersensitivity to DNA-damaging agents
1992 StandoutNobel
Saccharomyces cerevisiae Mre11/Rad50/Xrs2 and Ku proteins regulate association of Exo1 and Dna2 with DNA breaks
2010
Isolation of human Dna2 endonuclease and characterization of its enzymatic properties
2006
A novel nuclease-ATPase (Nar71) from archaea is part of a proposed thermophilic DNA repair system
2004
p65cdc18 Plays a major role controlling the initiation of DNA replication in fission yeast
1995 StandoutNobel
Mitotic transmission of artificial chromosomes in cdc mutants of the yeast, Saccharomyces cerevisiae.
1990
Transcription factor b (TFIIH) is required during nucleotide-excision repair in yeast
1994 StandoutNatureNobel
Telomere Dysfunction Increases Mutation Rate and Genomic Instability
2001 StandoutNobel
A Long Twentieth Century of the Cell Cycle and Beyond
2000 StandoutNobel
Reconstituted Okazaki Fragment Processing Indicates Two Pathways of Primer Removal
2006
Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family
2011 StandoutNobel
Checkpoint Pathways Come of Age
1997 StandoutNobel
Cleavage Specificity of Saccharomyces cerevisiae Flap Endonuclease 1 Suggests a Double-Flap Structure as the Cellular Substrate
2002
A third essential DNA polymerase in S. cerevisiae
1990
Characterization of the POL3 gene product from Schizosaccharomyces pombe indicates inter-species conservation of the catalytic subunit of DNA polymerase δ
1991
Electron Crystal Structure of the Transcription Factor and DNA Repair Complex, Core TFIIH
2000 StandoutNobel
Cdk1-Dependent Phosphorylation of Cdc13 Coordinates Telomere Elongation during Cell-Cycle Progression
2009 StandoutNobel
ERCC6, a member of a subfamily of putative helicases, is involved in Cockayne's syndrome and preferential repair of active genes
1992
Identification of the Xenopus DNA2 protein as a major nuclease for the 5'->3' strand-specific processing of DNA ends
2008
Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing
2008 Nature
Switching and Signaling at the Telomere
2001 StandoutNobel
Structure of the DNA Repair and Replication Endonuclease and Exonuclease FEN-1
1998
Sgs1 Helicase and Two Nucleases Dna2 and Exo1 Resect DNA Double-Strand Break Ends
2008
BLM–DNA2–RPA–MRN and EXO1–BLM–RPA–MRN constitute two DNA end resection machineries for human DNA break repair
2011 StandoutNobel
DNA end resection by Dna2–Sgs1–RPA and its stimulation by Top3–Rmi1 and Mre11–Rad50–Xrs2
2010 Nature
Where transcription meets repair
1994 StandoutNobel
Sequential initiation of lagging and leading strand synthesis by two different polymerase complexes at the SV40 DNA replication origin
1990 Nature
Mechanism of Inhibition of Proliferating Cell Nuclear Antigen-Dependent DNA Synthesis by the Cyclin-Dependent Kinase Inhibitor p21
1995
Processing of G4 DNA by Dna2 Helicase/Nuclease and Replication Protein A (RPA) Provides Insights into the Mechanism of Dna2/RPA Substrate Recognition
2008
The fission yeast cdc18+ gene product couples S phase to START and mitosis
1993 StandoutNobel
Biology and Applications of CRISPR Systems: Harnessing Nature’s Toolbox for Genome Engineering
2016 StandoutNobel
Mre11–Rad50–Xrs2 and Sae2 promote 5′ strand resection of DNA double-strand breaks
2010
CDC5 and CKII Control Adaptation to the Yeast DNA Damage Checkpoint
1997 StandoutNobel
The Biology of CRISPR-Cas: Backward and Forward
2018 StandoutNobel
Cell cycle arrest of cdc mutants and specificity of the RAD9 checkpoint.
1993 StandoutNobel
HYS2, an essential gene required for DNA replication inSaccharomyces cerevisiae
1995
DNA Ligase I and Proliferating Cell Nuclear Antigen Form a Functional Complex
2001
Nucleases: diversity of structure, function and mechanism
2010
Inhibition of Nucleotide Excision Repair by the Cyclin-dependent Kinase Inhibitor p21
1995 StandoutNobel
Polymerases and the Replisome: Machines within Machines
1998
Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection
2016 StandoutNatureNobel
Mechanism of Tracking and Cleavage of Adduct-damaged DNA Substrates by the Mammalian 5′- to 3′-Exonuclease/Endonuclease RAD2 Homologue 1 or Flap Endonuclease 1
1996
Excision Repair in Mammalian Cells
1995 StandoutNobel
Molecular mechanism of nucleotide excision repair
1999
RPA governs endonuclease switching during processing of Okazaki fragments in eukaryotes
2001 Nature
Universal control mechanism regulating onset of M-phase
1990 StandoutNatureNobel
Trex1 Exonuclease Degrades ssDNA to Prevent Chronic Checkpoint Activation and Autoimmune Disease
2007 StandoutNobel
RecBCD Enzyme and the Repair of Double-Stranded DNA Breaks
2008
Saccharomyces cerevisiae RNase H(35) Functions in RNA Primer Removal during Lagging-Strand DNA Synthesis, Most Efficiently in Cooperation with Rad27 Nuclease
1999
Nucleotide Sequence and Transcriptional Regulation of the Yeast Recombinational Repair Gene RAD51
1992
Checkpoints: Controls That Ensure the Order of Cell Cycle Events
1989 StandoutScienceNobel
Checkpoints and spindles
1991 StandoutNatureNobel
Identification of rad27 Mutations That Confer Differential Defects in Mutation Avoidance, Repeat Tract Instability, and Flap Cleavage
2001
Eukaryotic DNA polymerase amino acid sequence required for 3'----5' exonuclease activity.
1991
Quality Control by DNA Repair
1999 StandoutScienceNobel
Enzymologic mechanism of calf thymus DNA polymerase delta
1991
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
Cell Cycle Control and Cancer
1994 StandoutScienceNobel
The fission yeast Cdc1 protein, a homologue of the small subunit of DNA polymerase delta, binds to Pol3 and Cdc27.
1996 StandoutNobel
Structural Relationship of Bacterial RecA Proteins to Recombination Proteins from Bacteriophage T4 and Yeast
1993 StandoutScienceNobel
Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair.
1994 StandoutNobel
The human Bloom syndrome gene suppresses the DNA replication and repair defects of yeastdna2mutants
2003
Eukaryotic DNA Replication Fork
2017
S Phase of the Cell Cycle
1989 Science
Molecular Matchmakers
1993 StandoutScienceNobel
Cell cycle expression of two replicative DNA polymerases alpha and delta from Schizosaccharomyces pombe.
1993
Human Dna2 Is a Nuclear and Mitochondrial DNA Maintenance Protein
2009
THE DNA REPLICATION FORK IN EUKARYOTIC CELLS
1998
REV3, a Saccharomyces cerevisiae gene whose function is required for induced mutagenesis, is predicted to encode a nonessential DNA polymerase
1989
DNA polymerase epsilon may be dispensable for SV40- but not cellular-DNA replication.
1996
Genetic Interaction between Transcription Elongation Factor TFIIS and RNA Polymerase II
1992
The Incredible Life and Times of Biological Cells
2000 StandoutScienceNobel
ATP-independent loading of the proliferating cell nuclear antigen requires DNA ends.
1993
DNA polymerase I gene of Saccharomyces cerevisiae: nucleotide sequence, mapping of a temperature-sensitive mutation, and protein homology with other DNA polymerases.
1988
Interaction of proliferating cell nuclear antigen with yeast DNA polymerase delta.
1993
Schizosaccharomyces pombe cdc 20 + encodes DNA polymerase ɛ and is required for chromosomal replication but not for the S phase checkpoint
1997 StandoutNobel
A group of interacting yeast DNA replication genes.
1991
Hepatitis C Virus IRES RNA-Induced Changes in the Conformation of the 40 S Ribosomal Subunit
2001 StandoutScienceNobel
DNA polymerases alpha, delta, and epsilon: three distinct enzymes from HeLa cells.
1990
Flap Endonuclease 1: A Central Component of DNA Metabolism
2004
Addition of extra origins of replication to a minichromosome suppresses its mitotic loss in cdc6 and cdc14 mutants of Saccharomyces cerevisiae.
1992
p21Cip1/Waf1 disrupts the recruitment of human Fen1 by proliferating-cell nuclear antigen into the DNA replication complex.
1996
Yeast pip3/mec3 Mutants Fail To Delay Entry into S Phase and To Slow DNA Replication in Response to DNA Damage, and They Define a Functional Link between Mec3 and DNA Primase
1996
Human DNA Repair Genes
2001 StandoutScienceNobel
Functions of replication factor C and proliferating-cell nuclear antigen: functional similarity of DNA polymerase accessory proteins from human cells and bacteriophage T4.
1990
Integrating Genetic Approaches into the Discovery of Anticancer Drugs
1997 StandoutScienceNobel
Structural Basis of Transcription: RNA Polymerase II at 2.8 Ångstrom Resolution
2001 StandoutScienceNobel
Characterization of Double-Strand Break-Induced Recombination: Homology Requirements and Single-Stranded DNA Formation
1992
The human Rad9–Rad1–Hus1 checkpoint complex stimulates flap endonuclease 1
2004 StandoutNobel
Block in Anaphase Chromosome Separation Caused by a Telomerase Template Mutation
1997 StandoutScienceNobel
Dpb11, which interacts with DNA polymerase II(epsilon) in Saccharomyces cerevisiae, has a dual role in S-phase progression and at a cell cycle checkpoint.
1995
DNA polymerase II, the probable homolog of mammalian DNA polymerase epsilon, replicates chromosomal DNA in the yeast Saccharomyces cerevisiae.
1992
Reconfigurable asymmetric protein assemblies through implicit negative design
2022 StandoutScienceNobel
Works of Martin E. Budd being referenced
The Nuclease Activity of the Yeast Dna2 Protein, Which Is Related to the RecB-like Nucleases, Is Essential in Vivo
2000
The roles of the eukaryotic DNA polymerases in DNA repair synthesis
1997
The pattern of sensitivity of yeast dna2 mutants to DNA damaging agents suggests a role in DSB and postreplication repair pathways
2000
Interplay of Mre11 Nuclease with Dna2 plus Sgs1 in Rad51-Dependent Recombinational Repair
2009
Mrc1 and DNA Polymerase ɛ Function Together in Linking DNA Replication and the S Phase Checkpoint
2008
DNA2 Encodes a DNA Helicase Essential for Replication of Eukaryotic Chromosomes
1995
[12] Purification and enzymatic and functional characterization of DNA polymerase β-like enzyme, POL4, expressed during yeast meiosis
1995
Dna2 Helicase/Nuclease Causes Replicative Fork Stalling and Double-strand Breaks in the Ribosomal DNA of Saccharomyces cerevisiae
2003
A Network of Multi-Tasking Proteins at the DNA Replication Fork Preserves Genome Stability
2005
DNA polymerase III, a second essential DNA polymerase, is encoded by the S. cerevisiae CDC2 gene
1989
Purification of DNA Polymerase II, a Distinct DNA Polymerase, from Saccharomyces cerevisiae
1989
A Yeast Replicative Helicase, Dna2 Helicase, Interacts with Yeast FEN-1 Nuclease in Carrying Out Its Essential Function
1997
Mutations in DNA Replication Genes Reduce Yeast Life Span
2002
Temperature-sensitive mutations in the yeast DNA polymerase I gene.
1987
A yeast gene required for DNA replication encodes a protein with homology to DNA helicases.
1995
DNA Polymerases Required for Repair of UV-Induced Damage in Saccharomyces cerevisiae
1995
DNA polymerases delta and epsilon are required for chromosomal replication in Saccharomyces cerevisiae.
1993
Repair of double-strand breaks in a temperature conditional radiation-sensitive mutant of Saccharomyces cerevisiae
1982
Evidence Suggesting that Pif1 Helicase Functions in DNA Replication with the Dna2 Helicase/Nuclease and DNA Polymerase δ
2006
The Effect of Cycloheximide on Repair in a Temperature Conditional Radiation-Sensitive Mutant of Saccharomyces cerevisiae
1984
Dynamic Localization of an Okazaki Fragment Processing Protein Suggests a Novel Role in Telomere Replication
2002
DNA polymerase I is required for premeiotic DNA replication and sporulation but not for X-ray repair in Saccharomyces cerevisiae.
1989
The effect of cycloheximide on repair in a temperature conditional radiation-sensitive mutant of Saccharomyces cerevisiae.
1984
A Network of Multi-tasking Proteins at the DNA replication Fork Preserves Genome Stability
2005
DNA Polymerase I Is Required for Premeiotic DNA Replication and Sporulation but Not for X-Ray Repair in Saccharomyces cerevisiae
1989
DNA Polymerases δ and ε are Required for Chromosomal Replication in Saccharomyces cerevisiae
1993