Citation Impact
Citing Papers
Calorie Restriction Promotes Mammalian Cell Survival by Inducing the SIRT1 Deacetylase
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1999
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2001
The Antioxidant Vitamin E Modulates Amyloid β-Peptide-Induced Creatine Kinase Activity Inhibition and Increased Protein Oxidation: Implications for the Free Radical Hypothesis of Alzheimer's Disease
1999
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1995
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2007
Mitochondria, free radicals, and neurodegeneration
1996
Apoptosis in the nervous system
2000 StandoutNature
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2000
Protective effects of idebenone and α‐tocopherol on β‐amyloid‐(1–42)‐induced learning and memory deficits in rats: implication of oxidative stress in β‐amyloid‐induced neurotoxicity in vivo
1999
Molecular identification of a renal urate–anion exchanger that regulates blood urate levels
2002 StandoutNature
Oxidative Alterations in Alzheimer's Disease
1999
On the mechanism of the inhibition of glutamine synthetase and creatine phosphokinase by methionine sulfoxide
1996
Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases
2002 StandoutNature
Neuronal and glial calcium signaling in Alzheimer’s disease
2003
Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage
2000 StandoutNature
Elevated thiobarbituric acid-reactive substances and antioxidant enzyme activity in the brain in Alzheimer's disease
1995
Oxidative stress, inflammation, and cancer: How are they linked?
2010 Standout
Alzheimer Disease
1998
4-Hydroxynonenal, an aldehydic product of membrane lipid peroxidation, impairs glutamate transport and mitochondrial function in synaptosomes
1997
The inhibitory effects of β-amyloid on glutamate and glucose uptakes by cultured astrocytes
1997
Different amyloidogenic peptides share a similar mechanism of neurotoxicity involving reactive oxygen species and calcium
1995
Copper, iron, and zinc imbalances in severely degenerated brain regions in Alzheimer's disease: possible relation to oxidative stress
1996
Mechanisms of Neuronal Degeneration in Alzheimer's Disease
1996
Oxidative Stress Hypothesis in Alzheimer's Disease
1997 Standout
Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β
2000 StandoutNature
Glutamate uptake
2001 Standout
Oxidative Damage Is the Earliest Event in Alzheimer Disease
2001 Standout
Salen- Manganese Complexes: Combined Superoxide Dismutase/Catalase Mimics with Broad Pharmacological Efficacy
1996
Oxidative stress, dysfunctional glucose metabolism and Alzheimer disease
2019 Standout
Mitochondrial dysfunction, apoptotic cell death, and Alzheimer’s disease
2003
Neuronal and Glial Glutamate Transporters Possess an SH‐based Redox Regulatory Mechanism
1997
Copper, iron and zinc in Alzheimer's disease senile plaques
1998 Standout
Redox proteomics identification of 4‐hydroxynonenal‐modified brain proteins in Alzheimer's disease: Role of lipid peroxidation in Alzheimer's disease pathogenesis
2009
Soluble Oligomers of Amyloid β Protein Facilitate Hippocampal Long-Term Depression by Disrupting Neuronal Glutamate Uptake
2009
Redox proteomics identification of oxidatively modified hippocampal proteins in mild cognitive impairment: Insights into the development of Alzheimer's disease
2006
The Expression of Key Oxidative Stress-Handling Genes in Different Brain Regions in Alzheimer's Disease
1998
Amyloid‐β‐induced toxicity of primary neurons is dependent upon differentiation‐associated increases in tau and cyclin‐dependent kinase 5 expression
2003
Targeting oxidative stress in disease: promise and limitations of antioxidant therapy
2021 Standout
Inhibition of Glutamate Uptake by Unconjugated Bilirubin in Cultured Cortical Rat Astrocytes: Role of Concentration and pH
1999
Oxidative stress hypothesis in Alzheimer’s disease: a reappraisal
2008
The neurobiology of zinc in health and disease
2005 Standout
Oxidative stress and the amyloid beta peptide in Alzheimer’s disease
2017 Standout
Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress
2002 StandoutNature
Autoradiographic studies indicate regional variations in the characteristics of l-glutamate transporters in the rat brain
1996
Oxidative Stress in the Progression of Alzheimer Disease in the Frontal Cortex
2010
Wnt Signaling Induces GLT‐1 Expression in Rat C6 Glioma Cells
1999
Zinc takes the center stage: its paradoxical role in Alzheimer’s disease
2003
Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo
2002 StandoutNature
Radical AGEing in Alzheimer's disease
1995
Aggregation of Secreted Amyloid β-Protein into Sodium Dodecyl Sulfate-stable Oligomers in Cell Culture
1995
The mitochondria-targeted antioxidant MitoQ extends lifespan and improves healthspan of a transgenic Caenorhabditis elegans model of Alzheimer disease
2014
High Affinity Glutamate Transporters: Regulation of Expression and Activity
1997
Prion Protein Peptides Induce .alpha.-Helix to .beta.-Sheet Conformational Transitions
1995
Abnormal properties of creatine kinase in Alzheimer's disease brain: Correlation of reduced enzyme activity and active site photolabeling with aberrant cytosol-membrane partitioning
1998
The glial glutamate transporter, GLT‐1, is oxidatively modified by 4‐hydroxy‐2‐nonenal in the Alzheimer's disease brain: the role of Aβ1–42
2001
NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice
2012 StandoutNature
β-Lactam antibiotics offer neuroprotection by increasing glutamate transporter expression
2005 StandoutNature
Proteomic identification of oxidatively modified proteins in alzheimer’s disease brain. part I: creatine kinase BB, glutamine synthase, and ubiquitin carboxy-terminal hydrolase L-1
2002
[48] Amyloid β-peptide-associated free radical oxidative stress, neurotoxicity, and Alzheimer's disease
1999
Acrolein is increased in Alzheimer’s disease brain and is toxic to primary hippocampal cultures
2001
Proteomic identification of brain proteins in the canine model of human aging following a long-term treatment with antioxidants and a program of behavioral enrichment: Relevance to Alzheimer's disease
2006
Amyloid β-protein toxicity and oxidative stress in Alzheimer's disease
1997
Amyloid β-peptide and oxidative cellular injury in Alzheimer’s disease
1996
Life in extreme environments
2001 StandoutNature
Deuterated polyunsaturated fatty acids reduce brain lipid peroxidation and hippocampal amyloid β-peptide levels, without discernable behavioral effects in an APP/PS1 mutant transgenic mouse model of Alzheimer's disease
2018
Curcumin Inhibits Formation of Amyloid β Oligomers and Fibrils, Binds Plaques, and Reduces Amyloid in Vivo
2004 Standout
Calcium dyshomeostasis and intracellular signalling in alzheimer's disease
2002
Oxidative stress and Alzheimer disease
2000 Standout
Redox proteomic identification of 4-Hydroxy-2-nonenal-modified brain proteins in amnestic mild cognitive impairment: Insight into the role of lipid peroxidation in the progression and pathogenesis of Alzheimer's disease
2008
BCL-2 expression or antioxidants prevent hyperglycemia-induced formation of intracellular advanced glycation endproducts in bovine endothelial cells.
1996
Neurovascular regulation in the normal brain and in Alzheimer's disease
2004 Standout
An Assessment of Oxidative Damage to Proteins, Lipids, and DNA in Brain from Patients with Alzheimer's Disease
1997
Ageing and apoptosis
2002
Glutamate transporters are oxidant-vulnerable: a molecular link between oxidative and excitotoxic neurodegeneration?
1998
Malondialdehyde, carbonyl proteins and albumin-disulphide as useful oxidative markers in mild cognitive impairment and Alzheimer's disease
2008
Redox-active iron mediates amyloid-β toxicity
2001
Elevated 4-Hydroxynonenal in Ventricular Fluid in Alzheimer’s Disease
1997
Oxidative damage and the Nrf2-ARE pathway in neurodegenerative diseases
2014
Oxidants, oxidative stress and the biology of ageing
2000 StandoutNature
Quantitation of Protein-Bound 3-Nitrotyrosine and 3,4-Dihydroxyphenylalanine by High-Performance Liquid Chromatography with Electrochemical Array Detection
1997
Metalloenzyme-like Activity of Alzheimer's Disease β-Amyloid
2002
Alzheimer's Disease
2010 Standout
Oxidation of Cytosolic Proteins and Expression of Creatine Kinase BB in Frontal Lobe in Different Neurodegenerative Disorders
1999
Alzheimer's disease and Aβ toxicity: from top to bottom
2001
Reactive oxygen species and Alzheimer's disease
1997
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
2006 StandoutNature
Reactive oxygen species have a causal role in multiple forms of insulin resistance
2006 StandoutNature
Mitochondrial dysfunction in sporadic and genetic Alzheimer's disease
2006
Glia-Neuron Interaction by High-Affinity Glutamate Transporters in Neurotransmission
1999
Genetic analysis of ageing: role of oxidative damage and environmental stresses
1996
Biochemistry and molecular cell biology of diabetic complications
2001 StandoutNature
Increased oxidative damage in nuclear and mitochondrial DNA in Alzheimer's disease
2005
Involvement of oxidative stress in the enhancement of acetylcholinesterase activity induced by amyloid beta-peptide
2002
Abnormal Glutamate Transport Function in Mutant Amyloid Precursor Protein Transgenic Mice
2000
SOD1 rescues cerebral endothelial dysfunction in mice overexpressing amyloid precursor protein
1999
β‐Amyloid inhibits integrated mitochondrial respiration
and key enzyme activities
2001
Structural Selectivity and Molecular Nature ofl-Glutamate Transport in Cultured Human Fibroblasts
1998
Proteomic identification of nitrated brain proteins in early Alzheimer’s disease inferior parietal lobule
2008
Interindividual differences in the levels of the glutamate transporters GLAST and GLT, but no clear correlation with Alzheimer's disease
1999
17?-Estradiol attenuates oxidative impairment of synaptic Na+/K+-ATPase activity, glucose transport, and glutamate transport induced by amyloid ?-peptide and iron
1997
Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation
2011 StandoutNatureNobel
Oxidative stress in Alzheimer’s disease
2000
Are reactive oxygen species involved in Alzheimer's disease?
1995
Electron paramagnetic resonance investigations of free radical-induced alterations in neocortical synaptosomal membrane protein infrastructure
1994
Mitochondrial DNA damage and repair in neurodegenerative disorders
2008
Click Chemistry In Situ: Acetylcholinesterase as a Reaction Vessel for the Selective Assembly of a Femtomolar Inhibitor from an Array of Building Blocks
2002 StandoutNobel
Chapter 3 Properties and localization of glutamate transporters
1998
Oxidative modification and down-regulation of Pin1 in Alzheimer's disease hippocampus: A redox proteomics analysis
2005
Impaired Proteasome Function in Alzheimer's Disease
2000
β-Amyloid Enhances Glial Glutamate Uptake Activity and Attenuates Synaptic Efficacy
2002
Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein
1995 StandoutNobel
Oxidative stress and neurodegenerative disorders
1998
Activation of microglial cells by β-amyloid protein and interferon-γ
1995 Nature
Apolipoprotein E allele–specific antioxidant activity and effects on cytotoxicity by oxidative insults and β–amyloid peptides
1996
Exercise counteracts declining hippocampal function in aging and Alzheimer's disease
2012
Pathways towards and away from Alzheimer's disease
2004 StandoutNature
Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease
2008
Regional Membrane Phospholipid Alterations in Alzheimer's Disease
1998
Neuronal and Vascular Oxidative Stress in Alzheimers Disease
2011
Amyloid β interacts with the amyloid precursor protein: a potential toxic mechanism in Alzheimer's disease
2000
Four-Hydroxynonenal, a Product of Lipid Peroxidation, is Increased in the Brain in Alzheimer’s Disease
1998
Brain metabolism and brain disease: Is metabolic deficiency the proximate cause of Alzheimer dementia?
2001
Evidence of oxidative damage in Alzheimer's disease brain: central role for amyloid β-peptide
2001
Translating cell biology into therapeutic advances in Alzheimer's disease
1999 Nature
4-hydroxynonenal, a lipid peroxidation product, impairs glutamate transport in cortical astrocytes
1998
The p66shc adaptor protein controls oxidative stress response and life span in mammals
1999 StandoutNature
Free radicals and disruption of neuronal ion homeostasis in AD: A role for amyloid β-peptide?
1995
The Triangle of Death in Alzheimer's Disease Brain: The Aberrant Cross-Talk Among Energy Metabolism, Mammalian Target of Rapamycin Signaling, and Protein Homeostasis Revealed by Redox Proteomics
2016
Oxidative Stress, Amyloid-β Peptide, and Altered Key Molecular Pathways in the Pathogenesis and Progression of Alzheimer’s Disease
2018
Notch receptor cleavage depends on but is not directly executed by presenilins
2002 StandoutNobel
β-Amyloid-Associated Free Radical Oxidative Stress and Neurotoxicity: Implications for Alzheimer's Disease
1997
Copper Mediates Dityrosine Cross-Linking of Alzheimer's Amyloid-β
2003
beta-Amyloid toxicity in organotypic hippocampal cultures: protection by EUK-8, a synthetic catalytic free radical scavenger.
1996
An activity in rat tissues that modifies nitrotyrosine-containing proteins
1998 StandoutNobel
Specific Domains of β-Amyloid from Alzheimer Plaque Elicit Neuron Killing in Human Microglia
1996
Amyloid β-Peptide Impairs Glucose Transport in Hippocampal and Cortical Neurons: Involvement of Membrane Lipid Peroxidation
1997
Amyloid Fibrils Activate Tyrosine Kinase-Dependent Signaling and Superoxide Production in Microglia
1997
Tumor necrosis factors alpha and beta protect neurons against amyloid beta-peptide toxicity: evidence for involvement of a kappa B-binding factor and attenuation of peroxide and Ca2+ accumulation.
1995
The Free Radical Theory of Aging Matures
1998 Standout
Mitochondrial- and Endoplasmic Reticulum-Associated Oxidative Stress in Alzheimer's Disease: From Pathogenesis to Biomarkers
2012
Biochemistry and pathology of radical-mediated protein oxidation
1997
An intracellular protein that binds amyloid-β peptide and mediates neurotoxicity in Alzheimer's disease
1997 Nature
The Aβ Peptide of Alzheimer's Disease Directly Produces Hydrogen Peroxide through Metal Ion Reduction
1999
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
The Janus face of the heme oxygenase/biliverdin reductase system in Alzheimer disease: It's time for reconciliation
2013
Oxidative stress, cell cycle, and neurodegeneration
2003
Prion protein (PrP) synthetic peptides induce cellular PrP to acquire properties of the scrapie isoform.
1995 StandoutNobel
Mitochondrial Manganese Superoxide Dismutase Prevents Neural Apoptosis and Reduces Ischemic Brain Injury: Suppression of Peroxynitrite Production, Lipid Peroxidation, and Mitochondrial Dysfunction
1998
Calcium and neuronal injury in Alzheimer's disease. Contributions of beta-amyloid precursor protein mismetabolism, free radicals, and metabolic compromise.
1994
Fresh and nonfibrillar amyloid β protein(1–40) induces rapid cellular degeneration in aged human fibroblasts: evidence for AβP‐channel‐mediated cellular toxicity
2000
Bach1 Overexpression in Down Syndrome Correlates with the Alteration of the HO-1/BVR-A System: Insights for Transition to Alzheimer's Disease
2015
Conservation of the biochemical mechanisms of signal transduction among mammalian Notch family members
2001 StandoutNobel
Alzheimer's Disease: Genes, Proteins, and Therapy
2001 Standout
Mitochondrial Diseases in Man and Mouse
1999 StandoutScience
Mechanism of Oxidative Stress in Neurodegeneration
2012
Calcium and Neuronal Injury in Alzheimer's Disease
1994
Alzheimer's Disease Is a Synaptic Failure
2002 StandoutScience
New evidence that the Alzheimer β-amyloid peptide does not spontaneously form free radicals: An ESR study using a series of spin-traps
2001
The relationship between oxidative/nitrative stress and pathological inclusions in Alzheimer’s and Parkinson’s diseases1,2 11Guest Editors: Mark A. Smith and George Perry 22This article is part of a series of reviews on “Causes and Consequences of Oxidative Stress in Alzheimer’s Disease.” The full list of papers may be found on the homepage of the journal.
2002
Aβ-peptides enhance vasoconstriction in cerebral circulation
2001
Repetitive Mild Brain Trauma Accelerates Aβ Deposition, Lipid Peroxidation, and Cognitive Impairment in a Transgenic Mouse Model of Alzheimer Amyloidosis
2002
Amyloid-β Induces Smac Release via AP-1/Bim Activation in Cerebral Endothelial Cells
2002
Aggregated Amyloid-β Protein Induces Cortical Neuronal Apoptosis and Concomitant “Apoptotic” Pattern of Gene Induction
1997
Alzheimer Disease: from Molecular Biology to Therapy
1997
Converging Pathogenic Mechanisms in Vascular and Neurodegenerative Dementia
2003
Cloning and characterization of a functional human homolog of Escherichia coli endonuclease III
1997 StandoutNobel
Cu(II) Potentiation of Alzheimer Aβ Neurotoxicity
1999
Amyloid-β peptide–Receptor for Advanced Glycation Endproduct interaction elicits neuronal expression of macrophage-colony stimulating factor: A proinflammatory pathway in Alzheimer disease
1997
Reducing Endogenous Tau Ameliorates Amyloid ß-Induced Deficits in an Alzheimer's Disease Mouse Model
2007 StandoutScience
Coupled prediction of protein secondary and tertiary structure
2003 StandoutNobel
Melatonin Prevents Death of Neuroblastoma Cells Exposed to the Alzheimer Amyloid Peptide
1997
RAGE and amyloid-β peptide neurotoxicity in Alzheimer's disease
1996 StandoutNature
A novel neurological phenotype in mice lacking mitochondrial manganese superoxide dismutase
1998
Scrapie and cellular PrP isoforms are encoded by the same chromosomal gene
1986 StandoutNobel
Oxidative and Inflammatory Events in Prion Diseases: Can They Be Therapeutic Targets?
2019
Redox proteomics and amyloid β‐peptide: insights into Alzheimer disease
2018
ROS Generation in Microglia: Understanding Oxidative Stress and Inflammation in Neurodegenerative Disease
2020
Mutations in the DJ-1 Gene Associated with Autosomal Recessive Early-Onset Parkinsonism
2003 StandoutScience
Recombinant scrapie-like prion protein of 106 amino acids is soluble
1996 StandoutNobel
Free radical theory of aging: Alzheimer’s disease pathogenesis
1995
Creatine and Creatinine Metabolism
2000 Standout
Amyloid beta-peptide disrupts carbachol-induced muscarinic cholinergic signal transduction in cortical neurons.
1996
Works of Marni E. Harris being referenced
Brain Regional Correspondence Between Alzheimer's Disease Histopathology and Biomarkers of Protein Oxidation
1995
β-Amyloid Peptide Free Radical Fragments Initiate Synaptosomal Lipoperoxidation in a Sequence-Specific Fashion: Implications to Alzheimer′s Disease
1994
Detection of Oxidation Products in Individual Neurons by Fluorescence Microscopy
1994
Reactive Oxygen Species as Causal Agents in the Neurotoxicity of the Alzheimer's Disease‐Associated Amyloid Beta Peptidea
1996
Amyloid β Peptide (25–35) Inhibits Na+‐Dependent Glutamate Uptake in Rat Hippocampal Astrocyte Cultures
1996
β-Amyloid peptide-derived, oxygen-dependent free radicals inhibit glutamate uptake in cultured astrocytes: implications for Alzheimerʼs disease
1995
Direct evidence of oxidative injury produced by the Alzheimer's β-Amyloid peptide (1–40) in cultured hippocampal neurons
1995
A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer disease.
1994
Amyloid β-peptide spin trapping I
1995
A model for beta-amyloid aggregation and neurotoxicity based on the free radical generating capacity of the peptide: implications of "molecular shrapnel" for Alzheimer's disease.
1995
Enhancement of β‐Amyloid Peptide Aβ(1–40)‐Mediated Neurotoxicity by Glutamine Synthetase
1995
Amyloid β-peptide spin trapping II
1995