Markus Rey

Engineered Biosynthesis of β‐Alkyl Tryptophan Analogues

Wnt/β-catenin signalling: function, biological mechanisms, and therapeutic opportunities

Plant flavonoids: Classification, distribution, biosynthesis, and antioxidant activity

Distinct Mesenchymal Lineages and Niches Promote Epithelial Self-Renewal and Myofibrogenesis in the Lung

Protective Mechanisms of Quercetin Against Myocardial Ischemia Reperfusion Injury

Future Coastal Population Growth and Exposure to Sea-Level Rise and Coastal Flooding - A Global Assessment

Systemic sclerosis

Macitentan in pulmonary arterial hypertension: The SERAPHIN trial

Idiopathic pulmonary fibrosis

Synthetic approaches to the 2013 new drugs

Initial Use of Ambrisentan plus Tadalafil in Pulmonary Arterial Hypertension

Macitentan and Morbidity and Mortality in Pulmonary Arterial Hypertension

Usual Interstitial Pneumonia Can Be Detected in Transbronchial Biopsies Using Machine Learning

Engineered Biosynthesis of β‐Alkyl Tryptophan Analogues

Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019

Engineering enzymes for noncanonical amino acid synthesis

Catalytic Enantioselective Synthesis of Atropisomeric Biaryls: A Cation‐Directed Nucleophilic Aromatic Substitution Reaction

The Concise Guide to PHARMACOLOGY 2013/14: G Protein‐Coupled Receptors

Unusual Amino Acids in Medicinal Chemistry

Natural Products as Sources of New Drugs from 1981 to 2014

Microglial M1/M2 polarization and metabolic states

Modulators of Sphingosine-1-phosphate Pathway Biology: Recent Advances of Sphingosine-1-phosphate Receptor 1 (S1P₁) Agonists and Future Perspectives

Idiopathic Pulmonary Fibrosis

Recent advances and new concepts for the synthesis of axially stereoenriched biaryls

Novel S1P1 receptor agonists – Part 5: From amino-to alkoxy-pyridines

Desensitization by Progressive Up-Titration Prevents First-Dose Effects on the Heart: Guinea Pig Study with Ponesimod, a Selective S1P1 Receptor Modulator

Pharmacology of the Urotensin-II Receptor Antagonist Palosuran (ACT-058362; 1-[2-(4-Benzyl-4-hydroxy-piperidin-1-yl)-ethyl]-3-(2-methyl-quinolin-4-yl)-urea Sulfate Salt): First Demonstration of a Pathophysiological Role of the Urotensin System

Novel S1P 1 receptor agonists – Part 4: Alkylaminomethyl substituted aryl head groups

A Novel Genomic Signature with Translational Significance for Human Idiopathic Pulmonary Fibrosis

The Discovery of N-[5-(4-Bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy]-4-pyrimidinyl]-N′-propylsulfamide (Macitentan), an Orally Active, Potent Dual Endothelin Receptor Antagonist

Novel S1P₁ Receptor Agonists - Part 2: From Bicyclo[3.1.0]hexane-Fused Thiophenes to Isobutyl Substituted Thiophenes

4-((R)-2-{[6-((S)-3-Methoxypyrrolidin-1-yl)-2-phenylpyrimidine-4-carbonyl]amino}-3-phosphonopropionyl)piperazine-1-carboxylic Acid Butyl Ester (ACT-246475) and Its Prodrug (ACT-281959), a Novel P2Y₁₂ Receptor Antagonist with a Wider Therapeutic Window in the Rat Than Clopidogrel

Vascular Effects of Endothelin Receptor Antagonists Depends on Their Selectivity for ETA Versus ETB Receptors and on the Functionality of Endothelial ETB Receptors

Novel S1P₁ Receptor Agonists – Part 1: From Pyrazoles to Thiophenes

Novel S1P₁ Receptor Agonists − Part 3: From Thiophenes to Pyridines