Citation Impact
Citing Papers
Local Macrophage Proliferation, Rather than Recruitment from the Blood, Is a Signature of T H 2 Inflammation
2011 Science
Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes
2018 StandoutScienceNobel
Expansion of Monocytic Myeloid-Derived Suppressor Cells Dampens T Cell Function in HIV-1-Seropositive Individuals
2012
T cell metabolism drives immunity
2015
Programmed cell death 1 inhibits inflammatory helper T-cell development through controlling the innate immune response
2013 StandoutNobel
Arginase-Producing Myeloid Suppressor Cells in Renal Cell Carcinoma Patients: A Mechanism of Tumor Evasion
2005
SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase
2019 StandoutNobel
PD-L1-deficient mice show that PD-L1 on T cells, antigen-presenting cells, and host tissues negatively regulates T cells
2004
A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis
2021 StandoutScienceNobel
Immunometabolism and atherosclerosis: perspectives and clinical significance: a position paper from the Working Group on Atherosclerosis and Vascular Biology of the European Society of Cardiology
2019
Inducible costimulator is required for type 2 antibody isotype switching but not T helper cell type 2 responses in chronic nematode infection
2005 StandoutNobel
Selective delivery of β cell antigen to dendritic cells in vivo leads to deletion and tolerance of autoreactive CD8 + T cells in NOD mice
2008 StandoutNobel
Thioredoxin Peroxidase Secreted by Fasciola hepatica Induces the Alternative Activation of Macrophages
2004
Infectious tolerance via the consumption of essential amino acids and mTOR signaling
2009
Macrophage Expression of Hypoxia-Inducible Factor-1α Suppresses T-Cell Function and Promotes Tumor Progression
2010
The microbiota regulates type 2 immunity through RORγt + T cells
2015 StandoutScienceNobel
A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells
2012 StandoutScience
Resting Microglial Cells Are Highly Dynamic Surveillants of Brain Parenchyma in Vivo
2005 StandoutScience
Transcriptional Profiling of the Human Monocyte-to-Macrophage Differentiation and Polarization: New Molecules and Patterns of Gene Expression
2006 Standout
Differential Regulation of Nitric Oxide Synthase-2 and Arginase-1 by Type 1/Type 2 Cytokines In Vivo: Granulomatous Pathology Is Shaped by the Pattern of l -Arginine Metabolism
2001
CXCR2-Mediated Granulocytic Myeloid-Derived Suppressor Cells' Functional Characterization and Their Role in Maternal Fetal Interface
2016
IFN-γ-induced Th1-Treg polarization in inflamed brains limits exacerbation of experimental autoimmune encephalomyelitis
2024
Alternative Activation Is an Innate Response to Injury That Requires CD4+ T Cells to be Sustained during Chronic Infection
2007 StandoutNobel
IL-4 dependent alternatively-activated macrophages have a distinctive in vivo gene expression phenotype
2002
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
Reactive oxygen and reactive nitrogen intermediates in innate and specific immunity
2000
Alternative M2 Activation of Kupffer Cells by PPARδ Ameliorates Obesity-Induced Insulin Resistance
2008
Myeloid-derived suppressor cells coming of age
2018 Standout
Leishmaniasis
2018 Standout
Elements of cancer immunity and the cancer–immune set point
2017 StandoutNature
A subset of neutrophils in human systemic inflammation inhibits T cell responses through Mac-1
2011
Inflammation and cancer
2002 StandoutNature
Macrophages in chronic type 2 inflammation have a novel phenotype characterized by the abundant expression of Ym1 and Fizz1 that can be partly replicated in vitro
2003
Altered macrophage differentiation and immune dysfunction in tumor development
2007
Regulation of PD‐1, PD‐L1, and PD‐L2 expression during normal and autoimmune responses
2003
Neutrophils at work
2014 Standout
IFN-γ and pro-inflammatory cytokine production by antigen-presenting cells is dictated by intracellular thiol redox status regulated by oxygen tension
2002
A guide to immunometabolism for immunologists
2016 Standout
Krüppel-like factor 4 regulates macrophage polarization
2011
Other Functions, Other Genes
1999
Progressive Loss of Striatal Neurons Causes Motor Dysfunction in MND2 Mutant Mice and Is Not Prevented by Bcl-2
2002
Cytokines in Atherosclerosis: Pathogenic and Regulatory Pathways
2006
Mouse versus Human Neutrophils in Cancer: A Major Knowledge Gap
2017
Macrophages: Master Regulators of Inflammation and Fibrosis
2010 Standout
The changing landscape of atherosclerosis
2021 StandoutNature
Functional polarization of tumour-associated macrophages by tumour-derived lactic acid
2014 StandoutNature
IFN-γ production by antigen-presenting cells: mechanisms emerge
2001
Current Views on the Roles of Th1 and Th17 Cells in Experimental Autoimmune Encephalomyelitis
2010
Tumor‐induced tolerance and immune suppression by myeloid derived suppressor cells
2008
Granulomas in schistosome and mycobacterial infections: a model of local immune responses
2002
Human nutrition, the gut microbiome and the immune system
2011 StandoutNature
NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice
2012 StandoutNature
Macrophage-specific PPARγ controls alternative activation and improves insulin resistance
2007 StandoutNature
TH2 Cytokines and Allergic Challenge Induce Ym1 Expression in Macrophages by a STAT6-dependent Mechanism
2002
IL-4 Receptor Signaling Is Required for Mannose Receptor Expression by Macrophages Recruited to Granulomata but not Resident Cells in Mice Infected with Schistosoma mansoni
2003
Dissection of experimental asthma with DNA microarray analysis identifies arginase in asthma pathogenesis
2003
Upregulation of Arginase Expression in Wound-Derived Fibroblasts
2002
Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research
2006
Fibrotic disease and the TH1/TH2 paradigm
2004 Standout
Inflammatory cell infiltration of tumors: Jekyll or Hyde
2007
Oxidative metabolism and PGC-1β attenuate macrophage-mediated inflammation
2006
The Role of Myeloid-Derived Suppressor Cells in Immune Ontogeny
2014
FIZZ1 and Ym as Tools to Discriminate between Differentially Activated Macrophages
2002
Immunological Unresponsiveness Characterized by Increased Expression of CD5 on Peripheral T Cells Induced by Dendritic Cells In Vivo
2004
Arginase-1–Expressing Macrophages Suppress Th2 Cytokine–Driven Inflammation and Fibrosis
2009
Restoring function in exhausted CD8 T cells during chronic viral infection
2005 StandoutNatureNobel
Cancer immunotherapy comes of age
2011 StandoutNature
Macrophages as regulators of tumour immunity and immunotherapy
2019 Standout
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
2006 StandoutNature
Origin and physiological roles of inflammation
2008 StandoutNature
Heterogeneity of autoimmune diseases: pathophysiologic insights from genetics and implications for new therapies
2015
NOS-2 Mediates the Protective Anti-Inflammatory and Antifibrotic Effects of the Th1-Inducing Adjuvant, IL-12, in a Th2 Model of Granulomatous Disease
2000
Interleukin‐18 overproduction exacerbates the development of colitis with markedly infiltrated macrophages in interleukin‐18 transgenic mice
2003
Immunosuppressive activity enhances central carbon metabolism and bioenergetics in myeloid-derived suppressor cells in vitro models
2012
Alternatively activated macrophages induced by nematode infection inhibit proliferation via cell-to-cell contact
2000
Synergistic Innate and Adaptive Immune Response to Combination Immunotherapy with Anti-Tumor Antigen Antibodies and Extended Serum Half-Life IL-2
2015
Macrophage Metabolism As Therapeutic Target for Cancer, Atherosclerosis, and Obesity
2017
Neutrophils: Between Host Defence, Immune Modulation, and Tissue Injury
2015
Regulation of T Cell Receptor CD3ζ Chain Expression byl-Arginine
2002
Points of control in inflammation
2002 StandoutNature
Inflammation, Atherosclerosis, and Coronary Artery Disease
2005 Standout
Alternative Macrophage Activation Is Essential for Survival during Schistosomiasis and Downmodulates T Helper 1 Responses and Immunopathology
2004
Macrophage biology in development, homeostasis and disease
2013 StandoutNature
Protein‐energy malnutrition as a risk factor for visceral leishmaniasis: a review
2009
Regulation of immune responses by L-arginine metabolism
2005
Cancer-related inflammation
2008 StandoutNature
Inflammation, metaflammation and immunometabolic disorders
2017 StandoutNature
Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy
2016 StandoutNobel
Alternative activation of macrophages
2003 Standout
Host protective roles of type 2 immunity: Parasite killing and tissue repair, flip sides of the same coin
2014
Obesity induces a phenotypic switch in adipose tissue macrophage polarization
2007 Standout
Granulocytic myeloid-derived suppressor cells maintain feto-maternal tolerance by inducing Foxp3 expression in CD4+CD25−T cells by activation of the TGF-β/β-catenin pathway
2016
Inflammasomes in health and disease
2012 StandoutNature
Pembrolizumab versus Chemotherapy for PD-L1–Positive Non–Small-Cell Lung Cancer
2016 Standout
Early Expansion of Circulating Granulocytic Myeloid-derived Suppressor Cells Predicts Development of Nosocomial Infections in Patients with Sepsis
2017
Establishment of NOD-Pdcd1-/-mice as an efficient animal model of type I diabetes
2005 StandoutNobel
Type, Density, and Location of Immune Cells Within Human Colorectal Tumors Predict Clinical Outcome
2006 StandoutScience
The Strength of Persistent Antigenic Stimulation Modulates Adaptive Tolerance in Peripheral CD4+ T Cells
2003
Immunomodulation in Cystic Fibrosis: Why and How?
2020
Global Gene Expression Profiles During Acute Pathogen-Induced Pulmonary Inflammation Reveal Divergent Roles for Th1 and Th2 Responses in Tissue Repair
2003
Minute numbers of contaminant CD8+ T cells or CD11b+CD11c+ NK cells are the source of IFN-γ in IL-12/IL-18-stimulated mouse macrophage populations
2004
Granulocytic myeloid derived suppressor cells expand in human pregnancy and modulate T ‐cell responses
2014
Reduction of Myeloid-Derived Suppressor Cells and Induction of M1 Macrophages Facilitate the Rejection of Established Metastatic Disease
2005
Antagonistic effect of NK cells on alternatively activated monocytes: a contribution of NK cells to CTL generation
2002
Macrophages Sequentially Change Their Functional Phenotype in Response to Changes in Microenvironmental Influences
2005
Nitric oxide and the immune response
2001 Standout
M-1/M-2 Macrophages and the Th1/Th2 Paradigm
2000 Standout
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production
2008 StandoutNature
The Pathogenesis of Schistosomiasis Is Controlled by Cooperating IL-10-Producing Innate Effector and Regulatory T Cells
2004
Differential expression of FIZZ1 and Ym1 in alternatively versus classically activated macrophages
2002
Shaping Gene Expression in Activated and Resting Primary Macrophages by IL-10
2002
Arginase I in myeloid suppressor cells is induced by COX-2 in lung carcinoma
2005
Obstacles and opportunities for understanding macrophage polarization
2011
The role of microglia and macrophages in the pathophysiology of the CNS
1999
Granulocytic myeloid‐derived suppressor cells from human cord blood modulate T‐helper cell response towards an anti‐inflammatory phenotype
2017
Macrophage galactose-type C-type lectins as novel markers for alternatively activated macrophages elicited by parasitic infections and allergic airway inflammation
2004
Causes and consequences of higher Leishmania infantum burden in patients with kala‐azar: a study of 625 patients
2017
The PD-1/PD-L1 complex resembles the antigen-binding Fv domains of antibodies and T cell receptors
2008 StandoutNobel
Simultaneous inhibition of two regulatory T-cell subsets enhanced Interleukin-15 efficacy in a prostate tumor model
2012 StandoutNobel
Cutting Edge: Stat6-Dependent Substrate Depletion Regulates Nitric Oxide Production
2001
2000
Innate Immune Responses to Lung-Stage Helminth Infection Induce Alternatively Activated Alveolar Macrophages
2006
Blockade of B7/CD28 in mixed lymphocyte reaction cultures results in the generation of alternatively activated macrophages, which suppress T-cell responses
2002
Glycolipid α-C-galactosylceramide is a distinct inducer of dendritic cell function during innate and adaptive immune responses of mice
2006 StandoutNobel
PD-L1 and PD-L2 are differentially regulated by Th1 and Th2 cells
2003 StandoutNobel
CCR7 is involved in the migration of neutrophils to lymph nodes
2010
Overexpression of Interleukin-10 by Activated T Lymphocytes Inhibits Atherosclerosis in LDL Receptor–Deficient Mice by Altering Lymphocyte and Macrophage Phenotypes
2002
Molecular Mechanisms RegulatinG Th1 Immune Responses
2003
Nitric oxide-producing CD11b+Ly-6G(Gr-1)+CD31(ER-MP12)+cells in the spleen of cyclophosphamide–treated mice: implications for T-cell responses in immunosuppressed mice
2000
Frontline Science: Myeloid-derived suppressor cells (MDSCs) facilitate maternal–fetal tolerance in mice
2016
Arginase-1–dependent promotion of T H 17 differentiation and disease progression by MDSCs in systemic lupus erythematosus
2016
Alternative versus classical macrophage activation during experimental African trypanosomosis
2001
ABrugia malayiHomolog of Macrophage Migration Inhibitory Factor Reveals an Important Link Between Macrophages and Eosinophil Recruitment During Nematode Infection
2001
Nitric Oxide Mediation of Active Immunosuppression Associated With Graft-Versus-Host Reaction
1999
IL-13 Activates a Mechanism of Tissue Fibrosis That Is Completely TGF-β Independent
2004
Hepatitis C Virus–Induced Myeloid-Derived Suppressor Cells Suppress NK Cell IFN-γ Production by Altering Cellular Metabolism via Arginase-1
2016
Programmed death-1 concentration at the immunological synapse is determined by ligand affinity and availability
2007 StandoutNobel
The Serpin Proteinase Inhibitor 9 Is an Endogenous Inhibitor of Interleukin 1β–Converting Enzyme (Caspase-1) Activity in Human Vascular Smooth Muscle Cells
2000
The Inhibition of Arginase by Nω-Hydroxy-l -Arginine Controls the Growth of Leishmania Inside Macrophages
2001
2016
Enhancer-Mediated Control of Macrophage-Specific Arginase I Expression
2004
Nitric Oxide-Independent CTL Suppression during Tumor Progression: Association with Arginase-Producing (M2) Myeloid Cells
2003
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
Analysis of mannose receptor regulation by IL-4, IL-10, and proteolytic processing using novel monoclonal antibodies
2003
Impairment of Alternative Macrophage Activation Delays Cutaneous Leishmaniasis in Nonhealing BALB/c Mice
2006
Nitric oxide-producing CD11b+Ly-6G(Gr-1)+CD31(ER-MP12)+cells in the spleen of cyclophosphamide–treated mice: implications for T-cell responses in immunosuppressed mice
2000
Works of Markus Munder being referenced
Alternative Metabolic States in Murine Macrophages Reflected by the Nitric Oxide Synthase/Arginase Balance: Competitive Regulation by CD4+ T Cells Correlates with Th1/Th2 Phenotype
1998
Regulation of NK Cell Function by Human Granulocyte Arginase
2009
Th1/Th2-Regulated Expression of Arginase Isoforms in Murine Macrophages and Dendritic Cells
1999
Cytotoxicity of Tumor Antigen Specific Human T Cells Is Unimpaired by Arginine Depletion
2013
Arginine deficiency leads to impaired cofilin dephosphorylation in activated human T lymphocytes
2012
Characterization of a Novel Population of Low-Density Granulocytes Associated with Disease Severity in HIV-1 Infection
2012
Suppression of T-cell functions by human granulocyte arginase
2006
Arginase I is constitutively expressed in human granulocytes and participates in fungicidal activity
2004
Monocyte Dependent Regulation of Autoimmune Inflammation
2009
Arginase Activity in the Blood of Patients with Visceral Leishmaniasis and HIV Infection
2013
Age-Related Alteration of Arginase Activity Impacts on Severity of Leishmaniasis
2008
2009
Polymorphonuclear neutrophils and T lymphocytes: strange bedfellows or brothers in arms?
2009
Disease severity in patients with visceral leishmaniasis is not altered by co-infection with intestinal parasites
2017
Metabolism via Arginase or Nitric Oxide Synthase: Two Competing Arginine Pathways in Macrophages
2014
Arginase activity mediates reversible T cell hyporesponsiveness in human pregnancy
2007
Macrophage: SHIP of Immunity
2014
Arginase: an emerging key player in the mammalian immune system
2009
Increased Level of Arginase Activity Correlates with Disease Severity in HIV‐Seropositive Patients
2010
Murine Macrophages Secrete Interferon γ upon Combined Stimulation with Interleukin (IL)-12 and IL-18: A Novel Pathway of Autocrine Macrophage Activation
1998
Reduced Self-Reactivity of an Autoreactive T Cell After Activation with Cross-reactive Non–Self-Ligand
2002
T Cell Response in Experimental Autoimmune Encephalomyelitis (EAE): Role of Self and Cross-Reactive Antigens in Shaping, Tuning, and Regulating the Autopathogenic T Cell Repertoire
2002