Citation Impact
Citing Papers
High-resolution distance mapping in rhodopsin reveals the pattern of helix movement due to activation
2008
High-Resolution Crystal Structure of an Engineered Human β 2 -Adrenergic G Protein–Coupled Receptor
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GPCR Engineering Yields High-Resolution Structural Insights into β 2 -Adrenergic Receptor Function
2007 StandoutScienceNobel
Voltage sensor conformations in the open and closed states in rosetta structural models of K + channels
2006 StandoutNobel
SNARE Proteins: One to Fuse and Three to Keep the Nascent Fusion Pore Open
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De novo design of transmembrane β barrels
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Accurate computational design of multipass transmembrane proteins
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Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality
2009 StandoutNobel
A Model of Voltage Gating Developed Using the KvAP Channel Crystal Structure
2004
The structural basis of agonist-induced activation in constitutively active rhodopsin
2011 Nature
Amino acid distributions in integral membrane protein structures
2001
Solving the membrane protein folding problem
2005 Nature
Multiple Switches in G Protein-Coupled Receptor Activation
2009
Channel opening and gating mechanism in AMPA-subtype glutamate receptors
2017 StandoutNatureNobel
Ligand binding and micro-switches in 7TM receptor structures
2009
Microscale Fluorescent Thermal Stability Assay for Membrane Proteins
2008
Structure of the Disulfide Bond Generating Membrane Protein DsbB in the Lipid Bilayer
2013
Structure of rhodopsin and the metarhodopsin I photointermediate
2005
Crystal structure of the human β2 adrenergic G-protein-coupled receptor
2007 StandoutNatureNobel
Proline-induced Distortions of Transmembrane Helices
2002
Interaction of the M4 Segment with Other Transmembrane Segments Is Required for Surface Expression of Mammalian α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors
2011
High-resolution crystal structure of human protease-activated receptor 1
2012 StandoutNatureNobel
Lessons from constitutively active mutants of G protein-coupled receptors
2002
Multipass membrane protein structure prediction using Rosetta
2005 StandoutNobel
Structural determinants of water permeation through aquaporin-1
2000 StandoutNatureNobel
Structure and function of an irreversible agonist-β2 adrenoceptor complex
2011 StandoutNatureNobel
Rhodopsin structure, dynamics, and activation: A perspective from crystallography, site-directed spin labeling, sulfhydryl reactivity, and disulfide cross-linking
2003
Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor
2010 StandoutNatureNobel
3D Protein Structures by Solid‐State NMR Spectroscopy: Ready for High Resolution
2008
Crystal structure of the ligand-free G-protein-coupled receptor opsin
2008 Nature
Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist
2012 StandoutNatureNobel
Solid-state NMR studies of the structure and mechanisms of proteins
2002
Metal Ion Site Engineering Indicates a Global Toggle Switch Model for Seven-transmembrane Receptor Activation
2006
The coming of age of de novo protein design
2016 StandoutNatureNobel
Conformational changes in the G protein Gs induced by the β2 adrenergic receptor
2011 StandoutNatureNobel
Crystal structure of the β2 adrenergic receptor–Gs protein complex
2011 StandoutNatureNobel
The structure and function of G-protein-coupled receptors
2009 StandoutNatureNobel
Synthesis and Reactivity of 6,7‐dihydrogeranylazides: Reagents for Primary Azide Incorporation into Peptides and Subsequent Staudinger Ligation
2006
Structure of the TRPV1 ion channel determined by electron cryo-microscopy
2013 StandoutNatureNobel
Structure of a nanobody-stabilized active state of the β2 adrenoceptor
2011 StandoutNatureNobel
A Specific Cholesterol Binding Site Is Established by the 2.8 Å Structure of the Human β2-Adrenergic Receptor
2008
Crystal structure of the µ-opioid receptor bound to a morphinan antagonist
2012 StandoutNatureNobel
The Membrane- and Soluble-Protein Helix-Helix Interactome: Similar Geometry via Different Interactions
2015
Properties of integral membrane protein structures: Derivation of an implicit membrane potential
2005
Recent advances in magic angle spinning solid state NMR of membrane proteins
2014
Structure of a β1-adrenergic G-protein-coupled receptor
2008 StandoutNatureNobel
Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation
2011 StandoutNatureNobel
Interstrand Pairing Patterns in β-Barrel Membrane Proteins: The Positive-outside Rule, Aromatic Rescue, and Strand Registration Prediction
2005
Visual Rhodopsin Sees the Light: Structure and Mechanism of G Protein Signaling
2007
Structure and dynamics of the M3 muscarinic acetylcholine receptor
2012 StandoutNatureNobel
Overexpression of membrane proteins in mammalian cells for structural studies
2012
X-ray structure of a ClC chloride channel at 3.0 Å reveals the molecular basis of anion selectivity
2002 StandoutNatureNobel
PREDICT modeling and in‐silico screening for G‐protein coupled receptors
2004
Toward high-resolution prediction and design of transmembrane helical protein structures
2007 StandoutNobel
Helix-packing motifs in membrane proteins
2006
Folding of helical membrane proteins: the role of polar, GxxxG-like and proline motifs
2004
Reconstitution and functional comparison of purified GlpF and AqpZ, the glycerol and water channels from Escherichia coli
2001 StandoutNobel
Structure of the STRA6 receptor for retinol uptake
2016 StandoutScienceNobel
G Protein–Coupled Receptor Rhodopsin
2006
Cholesterol increases kinetic, energetic, and mechanical stability of the human β2-adrenergic receptor
2012 StandoutNobel
Arsenite transport by mammalian aquaglyceroporins AQP7 and AQP9
2002 StandoutNobel
Functional role of internal water molecules in rhodopsin revealed by x-ray crystallography
2002
Effective energy function for proteins in lipid membranes
2003
Structure of a Glycerol-Conducting Channel and the Basis for Its Selectivity
2000 Science
Generation of Candidate Ligands for Nicotinic Acetylcholine Receptors via in situ Click Chemistry with a Soluble Acetylcholine Binding Protein Template
2012 StandoutNobel
Tandem Facial Amphiphiles for Membrane Protein Stabilization
2010 StandoutNobel
Activation mechanism of theβ2-adrenergic receptor
2011
The NMR–Rosetta capsid model of M13 bacteriophage reveals a quadrupled hydrophobic packing epitope
2015 StandoutNobel
Structure-based discovery of β 2 -adrenergic receptor ligands
2009 StandoutNobel
Transmembrane-domain determinants for SNARE-mediated membrane fusion
2010
Computational Modeling Approaches to Structure−Function Analysis of G Protein-Coupled Receptors
2005
Structural imperatives impose diverse evolutionary constraints on helical membrane proteins
2009
Energy Landscapes as a Tool to Integrate GPCR Structure, Dynamics, and Function
2010 StandoutNobel
Crystal structure of metarhodopsin II
2011 Nature
MOLECULAR MECHANISM OF 7TM RECEPTOR ACTIVATION—A GLOBAL TOGGLE SWITCH MODEL
2006
Prediction of membrane protein structures with complex topologies using limited constraints
2009 StandoutNobel
Spin-Transfer Pathways in Paramagnetic Lithium Transition-Metal Phosphates from Combined Broadband Isotropic Solid-State MAS NMR Spectroscopy and DFT Calculations
2012 StandoutNobel
Update 1 of: Computational Modeling Approaches to Structure–Function Analysis of G Protein-Coupled Receptors
2011
Guest-to-Host Transmission of Structural Changes for Stimuli-Responsive Adsorption Property
2012 StandoutNobel
The effect of ligand efficacy on the formation and stability of a GPCR-G protein complex
2009 StandoutNobel
Structure and function in rhodopsin: High-level expression of rhodopsin with restricted and homogeneous N-glycosylation by a tetracycline-inducible N -acetylglucosaminyltransferase I-negative HEK293S stable mammalian cell line
2002
Inhibitors of Amyloid Toxicity Based on β-sheet Packing of Aβ40 and Aβ42
2006
Highly selective water channel activity measured by voltage clamp: Analysis of planar lipid bilayers reconstituted with purified AqpZ
2001 StandoutNobel
Folding of the C-terminal bacterial binding domain in statherin upon adsorption onto hydroxyapatite crystals
2006 StandoutNobel
A G protein-coupled receptor at work: the rhodopsin model
2009
Experimental Evidence for Intramolecular Blue-Shifting C−H···O Hydrogen Bonding by Matrix-Isolation Infrared Spectroscopy
2003 StandoutNobel
Aquaporin-4 square array assembly: Opposing actions of M1 and M23 isoforms
2003 StandoutNobel
On the energetics of translocon-assisted insertion of charged transmembrane helices into membranes
2010 StandoutNobel
Structure-guided SCHEMA recombination generates diverse chimeric channelrhodopsins
2017 StandoutNobel
Structural basis for gating charge movement in the voltage sensor of a sodium channel
2011 StandoutNobel
The Cα—H⋅⋅⋅O hydrogen bond: A determinant of stability and specificity in transmembrane helix interactions
2001
Works of Markus Eilers being referenced
Changes in Interhelical Hydrogen Bonding upon Rhodopsin Activation
2005
Location of the Retinal Chromophore in the Activated State of Rhodopsin
2009
Helix movement is coupled to displacement of the second extracellular loop in rhodopsin activation
2009
Structure and function of G protein-coupled receptors using NMR spectroscopy
2010
Helix Packing Moments Reveal Diversity and Conservation in Membrane Protein Structure
2004
Helix Packing in Polytopic Membrane Proteins: Role of Glycine in Transmembrane Helix Association
1999
Light Activation of Rhodopsin: Insights from Molecular Dynamics Simulations Guided by Solid-State NMR Distance Restraints
2009
Location of Trp265 in Metarhodopsin II: Implications for the Activation Mechanism of the Visual Receptor Rhodopsin
2006
Comparison of Helix Interactions in Membrane and Soluble α-Bundle Proteins
2002
Dipolar assisted rotational resonance NMR of tryptophan and tyrosine in rhodopsin
2004
Implications of Threonine Hydrogen Bonding in the Glycophorin A Transmembrane Helix Dimer
2002
Expression and purification of rhodopsin and its mutants from stable mammalian cell lines: application to NMR studies
1999
Evaluation of Isoprenoid Conformation in Solution and in the Active Site of Protein-Farnesyl Transferase Using Carbon-13 Labeling in Conjunction with Solution- and Solid-State NMR
2000
Comparison of Class A and D G Protein-Coupled Receptors: Common Features in Structure and Activation
2005
Internal packing of helical membrane proteins
2000
6-s-cis Conformation and Polar Binding Pocket of the Retinal Chromophore in the Photoactivated State of Rhodopsin
2009
Magic angle spinning NMR of the protonated retinylidene Schiff base nitrogen in rhodopsin: Expression of 15 N-lysine- and 13 C-glycine-labeled opsin in a stable cell line
1999
Coupling of retinal isomerization to the activation of rhodopsin
2004
Aromatic Residues at the Extracellular Ends of Transmembrane Domains 5 and 6 Promote Ligand Activation of the G Protein-Coupled α-Factor Receptor
2002
Role of group-conserved residues in the helical core of β 2 -adrenergic receptor
2007
The Cytoplasmic End of Transmembrane Domain 3 Regulates the Activity of the Saccharomyces cerevisiae G-Protein-Coupled α-Factor Receptor
2002
Highly conserved tyrosine stabilizes the active state of rhodopsin
2010