Citation Impact
Citing Papers
MutL traps MutS at a DNA mismatch
2015 StandoutNobel
Loss of the Mismatch Repair Protein MSH6 in Human Glioblastomas Is Associated with Tumor Progression during Temozolomide Treatment
2007
Mouse Embryonic Stem Cells, but Not Somatic Cells, Predominantly Use Homologous Recombination to Repair Double-Strand DNA Breaks
2010
Comprehensive molecular portraits of human breast tumours
2012 StandoutNature
Mutational landscape and significance across 12 major cancer types
2013 StandoutNature
Mismatch Repair-dependent Iterative Excision at Irreparable O6-Methylguanine Lesions in Human Nuclear Extracts
2006 StandoutNobel
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
2008 StandoutNature
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
Overexpression of cMOAT (MRP2/ABCC2) Is Associated with Decreased Formation of Platinum-DNA Adducts and Decreased G2-Arrest in Melanoma Cells Resistant to Cisplatin
2003
Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality
2009 StandoutNobel
Tipin-Replication Protein A Interaction Mediates Chk1 Phosphorylation by ATR in Response to Genotoxic Stress
2010 StandoutNobel
Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
2016 StandoutNature
The role of DNA damage and repair in aging through the prism of Koch-like criteria
2012
IDH1andIDH2Mutations in Gliomas
2009 Standout
Activation of mitogen-activated protein kinases by cisplatin and their role in cisplatin-resistance
2006
APE1/Ref-1Role in Redox Signaling: Translational Applications of Targeting the Redox Function of the DNA Repair/Redox Protein APE1/Ref-1
2011
How useful is SBF in predicting in vivo bone bioactivity?
2006 Standout
The interacting pathways for prevention and repair of oxidative DNA damage
2003
DFNA5 (ICERE‐1) contributes to acquired etoposide resistance in melanoma cells
2001
The DNA Damage Response Kinases DNA-dependent Protein Kinase (DNA-PK) and Ataxia Telangiectasia Mutated (ATM) Are Stimulated by Bulky Adduct-containing DNA
2011 StandoutNobel
An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor
2011 StandoutNature
Direct Visualization of Asymmetric Adenine Nucleotide-Induced Conformational Changes in MutLα
2008 StandoutNobel
Oxidative stress induces degradation of mitochondrial DNA
2009
DNA repair mechanisms in dividing and non-dividing cells
2013
Interactions of Human Mismatch Repair Proteins MutSα and MutLα with Proteins of the ATR-Chk1 Pathway
2009 StandoutNobel
Mismatch repair gene Msh2 modifies the timing of early disease in HdhQ111 striatum
2003
The Cancer Genome Atlas Pan-Cancer analysis project
2013 Standout
Signalling cell cycle arrest and cell death through the MMR System
2005
Molecular mechanisms of cisplatin resistance
2011 Standout
Alkylation damage in DNA and RNA—repair mechanisms and medical significance
2004
Structure of the Human MutSα DNA Lesion Recognition Complex
2007 StandoutNobel
An Engineered Protein Tag for Multiprotein Labeling in Living Cells
2008
Drug Resistance Towards Etoposide and Cisplatin in Human Melanoma Cells is Associated with Drug-Dependent Apoptosis Deficiency
2002
DNA Damage, Aging, and Cancer
2009 Standout
Multiple ATR-Chk1 Pathway Proteins Preferentially Associate with Checkpoint-Inducing DNA Substrates
2011 StandoutNobel
Cisplatin resistance: Preclinical findings and clinical implications
2010
Cisplatin resistance and oncogenes - a review
2000
Malignant Gliomas in Adults
2008 Standout
A structural model for regulation of NHEJ by DNA-PKcs autophosphorylation
2010
Role of DNA mismatch repair in apoptotic responses to therapeutic agents
2004
The Translesion Polymerase Rev3L in the Tolerance of Alkylating Anticancer Drugs
2009
Coupling of Human DNA Excision Repair and the DNA Damage Checkpoint in a Defined in Vitro System
2014 StandoutNobel
B cell–specific and stimulation-responsive enhancers derepress Aicda by overcoming the effects of silencers
2009 StandoutNobel
Primary brain tumours in adults
2012 Standout
Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling
2017 StandoutNatureNobel
Cisplatin sensitivity of testis tumour cells is due to deficiency in interstrand-crosslink repair and low ERCC1-XPF expression
2010
The Hallmarks of Aging
2013 Standout
DNA Repair in Mammalian Cells
2009
Cornerstones of CRISPR–Cas in drug discovery and therapy
2016 StandoutNobel
Loss of ATM sensitizes against O6-methylguanine triggered apoptosis, SCEs and chromosomal aberrations
2004
Pathological assessment of mismatch repair gene variants in Lynch syndrome: Past, present, and future
2012
Mammalian DNA mismatch repair protects cells from UVB-induced DNA damage by facilitating apoptosis and p53 activation
2003
Selective Inhibition of Hypoxia-Inducible Factor (HIF) Prolyl-Hydroxylase 1 Mediates Neuroprotection against Normoxic Oxidative Death via HIF- and CREB-Independent Pathways
2009 StandoutNobel
The cancer genome
2009 StandoutNature
A yeast model for the study of human DFNA5, a gene mutated in nonsyndromic hearing impairment
2003
Tethering DNA Damage Checkpoint Mediator Proteins Topoisomerase IIβ-binding Protein 1 (TopBP1) and Claspin to DNA Activates Ataxia-Telangiectasia Mutated and RAD3-related (ATR) Phosphorylation of Checkpoint Kinase 1 (Chk1)
2011 StandoutNobel
Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction
2009 Standout
Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin
2017 StandoutNature
Carboxy-terminal domain of AID required for its mRNA complex formation in vivo
2009 StandoutNobel
The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs
2016 Standout
Biochemical Modulation of Cisplatin Mechanisms of Action: Enhancement of Antitumor Activity and Circumvention of Drug Resistance
2003 Standout
TCGAbiolinks: an R/Bioconductor package for integrative analysis of TCGA data
2015 Standout
Inferring tumour purity and stromal and immune cell admixture from expression data
2013 Standout
The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data
2012 Standout
Tissue, cellular and subcellular events at a bone-ceramic hydroxylapatite interface.
1977
DNA polymerase β is able to repair breaks in switch regions and plays an inhibitory role during immunoglobulin class switch recombination
2007
Genomes in Focus: Development and Applications of CRISPR‐Cas9 Imaging Technologies
2017 StandoutNobel
Diagnosis and Treatment of Recurrent High-Grade Astrocytoma
2006
Fluorophore Targeting to Cellular Proteins via Enzyme-Mediated Azide Ligation and Strain-Promoted Cycloaddition
2012 StandoutNobel
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
AID-induced decrease in topoisomerase 1 induces DNA structural alteration and DNA cleavage for class switch recombination
2009 StandoutNobel
Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal
2013 Standout
The C-terminal region of activation-induced cytidine deaminase is responsible for a recombination function other than DNA cleavage in class switch recombination
2009 StandoutNobel
Non-DNA-binding platinum anticancer agents: Cytotoxic activities of platinum–phosphato complexes towards human ovarian cancer cells
2008
Evaluation of Molecular Models for the Affinity Maturation of Antibodies: Roles of Cytosine Deamination by AID and DNA Repair
2006
Differential regulation of S-region hypermutation and class-switch recombination by noncanonical functions of uracil DNA glycosylase
2014 StandoutNobel
Simultaneous precise editing of multiple genes in human cells
2019 StandoutNobel
APE1- and APE2-dependent DNA breaks in immunoglobulin class switch recombination
2007
Methylation of hypoxia-inducible factor (HIF)-1α by G9a/GLP inhibits HIF-1 transcriptional activity and cell migration
2018 StandoutNobel
Mechanism and Regulation of Class Switch Recombination
2008
Reactive oxygen species generating systems meeting challenges of photodynamic cancer therapy
2016 Standout
Drug Resistance in Cancer: An Overview
2014 Standout
APE1 is dispensable for S-region cleavage but required for its repair in class switch recombination
2014 StandoutNobel
SERIES: Genomic instability in cancer Balancing repair and tolerance of DNA damage caused by alkylating agents
2012
Works of Markus Christmann being referenced
Cisplatin-Induced Apoptosis Involves Membrane Fluidification via Inhibition of NHE1 in Human Colon Cancer Cells
2007
O6-Methylguanine-DNA methyltransferase (MGMT) in normal tissues and tumors: Enzyme activity, promoter methylation and immunohistochemistry
2011
MGMT activity, promoter methylation and immunohistochemistry of pretreatment and recurrent malignant gliomas: a comparative study on astrocytoma and glioblastoma
2010
MGMT: Key node in the battle against genotoxicity, carcinogenicity and apoptosis induced by alkylating agents
2007
Transcriptional regulation of human DNA repair genes following genotoxic stress: trigger mechanisms, inducible responses and genotoxic adaptation
2013
Long‐term activation of SAPK/JNK, p38 kinase and fas‐L expression by cisplatin is attenuated in human carcinoma cells that acquired drug resistance
2004
Phosphorylation of mismatch repair proteins MSH2 and MSH6 affecting MutSalpha mismatch-binding activity
2002
BER, MGMT, and MMR in defense against alkylation-induced genotoxicity and apoptosis
2001
Targeting O 6-methylguanine-DNA methyltransferase with specific inhibitors as a strategy in cancer therapy
2010
Nuclear Translocation of Mismatch Repair Proteins MSH2 and MSH6 as a Response of Cells to Alkylating Agents
2000
Mechanisms of human DNA repair: an update
2003
DNA repair in resistance to alkylating anticancer drugs
2002
Expression of DNA repair proteins hMSH2, hMSH6, hMLH1,O6-methylguanine-DNA methyltransferase and N-methylpurine-DNA glycosylase in melanoma cells with acquired drug resistance
1999
Mouse embryonic stem cells are hypersensitive to apoptosis triggered by the DNA damage O6-methylguanine due to high E2F1 regulated mismatch repair
2007
Acquired resistance of melanoma cells to the antineoplastic agent fotemustine is caused by reactivation of the DNA repair gene mgmt
2001