Standout Papers
Citation Impact
Citing Papers
Contextual Synthetic Lethality of Cancer Cell Kill Based on the Tumor Microenvironment
2010
The Pervasive Presence of Fluctuating Oxygenation in Tumors
2008
Roles of DNA repair and reductase activity in the cytotoxicity of the hypoxia-activated dinitrobenzamide mustard PR-104A
2009
Regulation of the Histone Demethylase JMJD1A by Hypoxia-Inducible Factor 1α Enhances Hypoxic Gene Expression and Tumor Growth
2009
Relation of a Hypoxia Metagene Derived from Head and Neck Cancer to Prognosis of Multiple Cancers
2007
Hypoxia‐inducible factors: coupling glucose metabolism and redox regulation with induction of the breast cancer stem cell phenotype
2016 StandoutNobel
Molecular imaging of hypoxia with radiolabelled agents
2009
High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq
2011 StandoutNobel
Concordant Regulation of Gene Expression by Hypoxia and 2-Oxoglutarate-dependent Dioxygenase Inhibition
2006 StandoutNobel
The EGLN-HIF O 2 -Sensing System: Multiple Inputs and Feedbacks
2017 StandoutNobel
Genome-wide Association of Hypoxia-inducible Factor (HIF)-1α and HIF-2α DNA Binding with Expression Profiling of Hypoxia-inducible Transcripts
2009 StandoutNobel
Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m 6 A-demethylation of NANOG mRNA
2016 StandoutNobel
Hypoxia-Inducible Factors in Physiology and Medicine
2012 StandoutNobel
Head and neck squamous cell carcinoma
2020 Standout
Tuning the Transcriptional Response to Hypoxia by Inhibiting Hypoxia-inducible Factor (HIF) Prolyl and Asparaginyl Hydroxylases
2016 StandoutNobel
Up‐regulation of gene expression by hypoxia is mediated predominantly by hypoxia‐inducible factor 1 (HIF‐1)
2005
Assessing Tumor Hypoxia in Cervical Cancer by PET with 60Cu-Labeled Diacetyl-Bis(N4-Methylthiosemicarbazone)
2008
Suppression of tumor growth through disruption of hypoxia-inducible transcription
2000 StandoutNobel
Hypoxia and radiotherapy: opportunities for improved outcomes in cancer treatment
2007
Targeting hypoxia in cancer therapy
2011 Standout
Hypoxia targeted bifunctional suicide gene expression enhances radiotherapy in vitro and in vivo
2012
The Histone Demethylases JMJD1A and JMJD2B Are Transcriptional Targets of Hypoxia-inducible Factor HIF
2008
Prognostic Potential Of The Pretherapeutic Tumor Oxygenation Status
2008
The prognostic value of pimonidazole and tumour pO2 in human cervix carcinomas after radiation therapy: A prospective international multi-center study
2006
Comparison of hypoxia-induced replication arrest with hydroxyurea and aphidicolin-induced arrest
2003
Chemical Radiosensitizers for Use in Radiotherapy
2007
Hypoxia Regulates CD44 and Its Variant Isoforms through HIF-1α in Triple Negative Breast Cancer
2012 StandoutNobel
Cell-cycle checkpoints and cancer
2004 StandoutNature
Hypoxia in human soft tissue sarcomas: Adverse impact on survival and no association with p53 mutations
2001
Overexpression of Intrinsic Hypoxia Markers HIF1α and CA-IX Predict for Local Recurrence in Stage T1-T2 Glottic Laryngeal Carcinoma Treated With Radiotherapy
2008
The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5
2009
Lung Cancer
2008 Standout
Tumor hypoxia is independent of hemoglobin and prognostic for loco-regional tumor control after primary radiotherapy in advanced head and neck cancer
2004
Large meta-analysis of multiple cancers reveals a common, compact and highly prognostic hypoxia metagene
2010
Invasive oxygen measurements and pimonidazole labeling in human cervix carcinoma
2001
Influence of tumour micro-environment heterogeneity on therapeutic response
2013 StandoutNature
Imaging oxygenation of human tumours
2006
Oxygen sensing by HIF hydroxylases
2004 StandoutNobel
Bevacizumab plus Radiotherapy–Temozolomide for Newly Diagnosed Glioblastoma
2014 Standout
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
Examining the relationship between Cu-ATSM hypoxia selectivity and fatty acid synthase expression in human prostate cancer cell lines
2008
Hypoxia-inducible factor–dependent breast cancer–mesenchymal stem cell bidirectional signaling promotes metastasis
2012 StandoutNobel
Oxygen sensing and hypoxia signalling pathways in animals: the implications of physiology for cancer
2013 StandoutNobel
Autophagy is required during cycling hypoxia to lower production of reactive oxygen species
2009
Spectroelectrochemical and Computational Studies on the Mechanism of Hypoxia Selectivity of Copper Radiopharmaceuticals
2008
Regulation of angiogenesis by hypoxia: role of the HIF system
2003 StandoutNobel
Hypoxia in cancer: significance and impact on clinical outcome
2007 Standout
Development of a hypoxia-responsive vector for tumor-specific gene therapy
2000
Common genetic variants at the 11q13.3 renal cancer susceptibility locus influence binding of HIF to an enhancer of cyclin D1 expression
2012 StandoutNobel
Malignant Gliomas in Adults
2008 Standout
Human AlkB Homologue 5 Is a Nuclear 2-Oxoglutarate Dependent Oxygenase and a Direct Target of Hypoxia-Inducible Factor 1α (HIF-1α)
2011 StandoutNobel
The Hypoxic Tumour Microenvironment, Patient Selection and Hypoxia-modifying Treatments
2007
Inflammation and cancer: back to Virchow?
2001 Standout
Immunohistochemical detection of osteopontin in advanced head-and-neck cancer: Prognostic role and correlation with oxygen electrode measurements, hypoxia-inducible-factor-1α-related markers, and hemoglobin levels
2006
Macrophage Migration Inhibitory Factor Activates Hypoxia-Inducible Factor in a p53-Dependent Manner
2008 StandoutNobel
The prognostic value of endogenous hypoxia-related markers for head and neck squamous cell carcinomas treated with ARCON
2006
Exploring the role of cancer stem cells in radioresistance
2008
Primary brain tumours in adults
2012 Standout
The Inflammasomes
2010 Standout
Negative Regulation of Hypoxic Responses via Induced Reptin Methylation
2010 StandoutNobel
Clonal evolution in cancer
2012 StandoutNature
ATR/ATM Targets Are Phosphorylated by ATR in Response to Hypoxia and ATM in Response to Reoxygenation
2003
Gene expression and hypoxia in breast cancer
2011
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
Expression and Prognostic Significance of a Panel of Tissue Hypoxia Markers in Head-and-Neck Squamous Cell Carcinomas
2007
Solving the Puzzle of Metastasis: The Evolution of Cell Migration in Neoplasms
2011
A confirmatory prognostic study on oxygenation status and loco-regional control in advanced head and neck squamous cell carcinoma treated by radiation therapy
2000
The comet assay: a method to measure DNA damage in individual cells
2006
Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling
2009 Standout
Prognostic significance of tumor oxygenation in humans
2003
Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics
2009 StandoutNobel
Up-regulation of Apoptosis Inhibitory Protein IAP-2 by Hypoxia
2001 StandoutNobel
Spermidine/Spermine N1-Acetyltransferase-1 Binds to Hypoxia-inducible Factor-1α (HIF-1α) and RACK1 and Promotes Ubiquitination and Degradation of HIF-1α
2007 StandoutNobel
Clinical Applications of PET in Brain Tumors
2007
Hypoxic activation of the unfolded protein response (UPR) induces expression of the metastasis-associated gene LAMP3
2009
Detection and Characterization of Tumor Hypoxia Using pO 2 Histography
2007
HypoxamiRs and Cancer: From Biology to Targeted Therapy
2013
Micelle-Encapsulated Quantum Dot-Porphyrin Assemblies as in Vivo Two-Photon Oxygen Sensors
2015 StandoutNobel
Photothermal therapy and photoacoustic imaging via nanotheranostics in fighting cancer
2018 Standout
Tirapazamine, Cisplatin, and Radiation Versus Cisplatin and Radiation for Advanced Squamous Cell Carcinoma of the Head and Neck (TROG 02.02, HeadSTART): A Phase III Trial of the Trans-Tasman Radiation Oncology Group
2010
Digoxin and other cardiac glycosides inhibit HIF-1α synthesis and block tumor growth
2008 StandoutNobel
Coordinating Radiometals of Copper, Gallium, Indium, Yttrium, and Zirconium for PET and SPECT Imaging of Disease
2010 Standout
Chronic Hypoxia Decreases Synthesis of Homologous Recombination Proteins to Offset Chemoresistance and Radioresistance
2008
Acidic Extracellular pH Promotes Experimental Metastasis of Human Melanoma Cells in Athymic Nude Mice
2006
Homologous Recombination Is the Principal Pathway for the Repair of DNA Damage Induced by Tirapazamine in Mammalian Cells
2008
Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosis
2015 StandoutNobel
Candidate genes for the hypoxic tumor phenotype.
2000
Hypoxia Links ATR and p53 through Replication Arrest
2002
Adaptive and Maladaptive Cardiorespiratory Responses to Continuous and Intermittent Hypoxia Mediated by Hypoxia-Inducible Factors 1 and 2
2012 StandoutNobel
Nanotechnology for Multimodal Synergistic Cancer Therapy
2017 Standout
Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment
2018 StandoutNobel
Hypoxic Stress Induces Dimethylated Histone H3 Lysine 9 through Histone Methyltransferase G9a in Mammalian Cells
2006
Rescue of hypoxia-inducible factor-1alpha-deficient tumor growth by wild-type cells is independent of vascular endothelial growth factor
2002
Synthesis, X‐ray Crystallography, Spectroelectrochemistry and Computational Studies on Potential Copper‐Based Radiopharmaceuticals
2008
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
Tumor Hypoxia Imaging with [F-18] Fluoromisonidazole Positron Emission Tomography in Head and Neck Cancer
2006
104 candidate genes for the hypoxic tumor phenotype
1999
Methylation of hypoxia-inducible factor (HIF)-1α by G9a/GLP inhibits HIF-1 transcriptional activity and cell migration
2018 StandoutNobel
Bevacizumab Plus Irinotecan in Recurrent Glioblastoma Multiforme
2007 Standout
The hypoxic cell: a target for selective cancer therapy--eighteenth Bruce F. Cain Memorial Award lecture.
1999
HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells
2015 StandoutNobel
HIF-1 and human disease: one highly involved factor
2000 StandoutNobel
Reactive oxygen species generating systems meeting challenges of photodynamic cancer therapy
2016 Standout
Works of Markus Adam being referenced
DNA Damage Measured by the Comet Assay in Head and Neck Cancer Patients Treated with Tirapazamine
1999
11C-methionine PET improves the target volume delineation of meningiomas treated with stereotactic fractionated radiotherapy
2006
The role of pentoxifylline as a modifier of radiation therapy
2005
Tissue oxygen distribution in head and neck cancer patients
1999
Oxygen tension measurements of tumors growing in mice
1999
Prognostic value of tumor oxygenation in 397 head and neck tumors after primary radiation therapy. An international multi-center study
2005 Standout
PAI-1 levels predict response to fractionated irradiation in 10 human squamous cell carcinoma lines of the head and neck
2008
Therapeutic options for recurrent high-grade glioma in adult patients: Recent advances
2006