Standout Papers
Citation Impact
Citing Papers
Phospholipid methylation controls Atg32‐mediated mitophagy and Atg8 recycling
2015 StandoutNobel
Human Multipotent Adipose-Derived Stem Cells Differentiate into Functional Brown Adipocytes
2009
Adipose Tissue Overexpression of Vascular Endothelial Growth Factor Protects Against Diet-Induced Obesity and Insulin Resistance
2012
BAR502, a dual FXR and GPBAR1 agonist, promotes browning of white adipose tissue and reverses liver steatosis and fibrosis
2017
EBF2 Determines and Maintains Brown Adipocyte Identity
2013
Brown fat activation reduces hypercholesterolaemia and protects from atherosclerosis development
2015
A split, conditionally active mimetic of IL-2 reduces the toxicity of systemic cytokine therapy
2022 StandoutNobel
The adipose organ of obesity-prone C57BL/6J mice is composed of mixed white and brown adipocytes
2012
Effect of Sedation With Dexmedetomidine vs Lorazepam on Acute Brain Dysfunction in Mechanically Ventilated Patients
2007 Standout
Mice lacking Pctp /StarD2 exhibit increased adaptive thermogenesis and enlarged mitochondria in brown adipose tissue
2009
Dexmedetomidine vs Midazolam for Sedation of Critically Ill Patients<subtitle>A Randomized Trial</subtitle>
2009 Standout
An Expanded View of Complex Traits: From Polygenic to Omnigenic
2017 Standout
Adipose Subtype-Selective Recruitment of TLE3 or Prdm16 by PPARγ Specifies Lipid Storage versus Thermogenic Gene Programs
2013
Mitochondrial uncoupling and lifespan
2010
Brown and Beige Fat: Physiological Roles beyond Heat Generation
2015
Recruited brown adipose tissue as an antiobesity agent in humans
2013
Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice
2010
Current and Future Drug Targets in Weight Management
2010
Biochemistry and pathophysiology of intravascular and intracellular lipolysis
2013
NEW AGENTS FOR SEDATION IN THE INTENSIVE CARE UNIT
2001
Xbp1s in Pomc Neurons Connects ER Stress with Energy Balance and Glucose Homeostasis
2014
Adipose tissue browning and metabolic health
2013
A Classical Brown Adipose Tissue mRNA Signature Partly Overlaps with Brite in the Supraclavicular Region of Adult Humans
2013
MicroRNA networks regulate development of brown adipocytes
2013
Inflammatory links between obesity and metabolic disease
2011 Standout
Proteome Differences between Brown and White Fat Mitochondria Reveal Specialized Metabolic Functions
2009
Brown and beige fat: development, function and therapeutic potential
2013 Standout
A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis
2012 StandoutNature
AMPK: guardian of metabolism and mitochondrial homeostasis
2017 Standout
PPARγ agonists Induce a White-to-Brown Fat Conversion through Stabilization of PRDM16 Protein
2012
Pten Positively Regulates Brown Adipose Function, Energy Expenditure, and Longevity
2012
Chronic inflammation in the etiology of disease across the life span
2019 Standout
Pharmacological and nutritional agents promoting browning of white adipose tissue
2012
Developmental Origins of the Adipocyte Lineage: New Insights from Genetics and Genomics Studies
2011
Clonal analyses and gene profiling identify genetic biomarkers of the thermogenic potential of human brown and white preadipocytes
2015
Autophagy in mammalian development and differentiation
2010 Standout
Evidence for two types of brown adipose tissue in humans
2013
Peroxisome Proliferator-activated Receptor α (PPARα) Induces PPARγ Coactivator 1α (PGC-1α) Gene Expression and Contributes to Thermogenic Activation of Brown Fat
2011
Brown-fat paucity due to impaired BMP signalling induces compensatory browning of white fat
2013 Nature
Metabolic Regulation of Hematopoietic Stem Cells in the Hypoxic Niche
2011 StandoutNobel
Aifm2, a NADH Oxidase, Supports Robust Glycolysis and Is Required for Cold- and Diet-Induced Thermogenesis
2020
Cardiac natriuretic peptides act via p38 MAPK to induce the brown fat thermogenic program in mouse and human adipocytes
2012
Mitochondrial Dysfunction in C. elegans Activates Mitochondrial Relocalization and Nuclear Hormone Receptor-Dependent Detoxification Genes
2019 StandoutNobel
Adrenergic Regulation of AMP-activated Protein Kinase in Brown Adipose Tissue in Vivo
2011
Essential Role for miR-196a in Brown Adipogenesis of White Fat Progenitor Cells
2012
Central Control of Brown Adipose Tissue Thermogenesis
2012
Treatment of Obesity with Celastrol
2015 Standout
Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodies
2008 Standout
The Human Transcription Factors
2018 Standout
Uncoupling protein-1 is not leaky
2010
The Vascular Endothelium of the Adipose Tissue Gives Rise to Both White and Brown Fat Cells
2012
PTEN Loss in the Myf5 Lineage Redistributes Body Fat and Reveals Subsets of White Adipocytes that Arise from Myf5 Precursors
2012
Autophagy: Renovation of Cells and Tissues
2011 Standout
Adipose tissue plasticity: how fat depots respond differently to pathophysiological cues
2016
Mitochondria: In Sickness and in Health
2012 Standout
Super-Enhancers in the Control of Cell Identity and Disease
2013 Standout
Host Remodeling of the Gut Microbiome and Metabolic Changes during Pregnancy
2012 Standout
Brown adipose tissue activity controls triglyceride clearance
2011
Mechanisms of NAFLD development and therapeutic strategies
2018 Standout
ERRγ Preserves Brown Fat Innate Thermogenic Activity
2018
Metazoan MicroRNAs
2018 Standout
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
Obesity and Cardiovascular Disease: A Scientific Statement From the American Heart Association
2021 Standout
Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease
2010 Standout
The different shades of fat
2014 Nature
TRPV4 Is a Regulator of Adipose Oxidative Metabolism, Inflammation, and Energy Homeostasis
2012
Brown adipose tissue regulates glucose homeostasis and insulin sensitivity
2012
A within-trial cost-effectiveness analysis of primary care referral to a commercial provider for weight loss treatment, relative to standard care—an international randomised controlled trial
2012 Standout
MyomiR-133 regulates brown fat differentiation through Prdm16
2012
Autophagy in Human Health and Disease
2013 Standout
Beige Adipocytes Are a Distinct Type of Thermogenic Fat Cell in Mouse and Human
2012 Standout
Growth Differentiation Factor 11 Is a Circulating Factor that Reverses Age-Related Cardiac Hypertrophy
2013 Standout
Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity
2018 StandoutNobel
Brown adipose tissue oxidative metabolism contributes to energy expenditure during acute cold exposure in humans
2012
Adipose Tissue-specific Inhibition of Hypoxia-inducible Factor 1α Induces Obesity and Glucose Intolerance by Impeding Energy Expenditure in Mice*
2010
Autophagy regulates adipose mass and differentiation in mice
2009
Thermogenic adipocytes promote HDL turnover and reverse cholesterol transport
2017
Programmed Cell Senescence during Mammalian Embryonic Development
2013 Standout
Chronic Peroxisome Proliferator-activated Receptor γ (PPARγ) Activation of Epididymally Derived White Adipocyte Cultures Reveals a Population of Thermogenically Competent, UCP1-containing Adipocytes Molecularly Distinct from Classic Brown Adipocytes
2009
Understanding the brown adipocyte as a contributor to energy homeostasis
2013
Adaptive thermogenesis in adipocytes: Is beige the new brown?
2013
BAT: a new target for human obesity?
2009
Initiation of myoblast to brown fat switch by a PRDM16–C/EBP-β transcriptional complex
2009 Nature
Human Brown Adipose Tissue
2010
Functional characterization of UCP1 in mammalian HEK293 cells excludes mitochondrial uncoupling artefacts and reveals no contribution to basal proton leak
2012
What We Talk About When We Talk About Fat
2014 Standout
High Prevalence of Brown Adipose Tissue in Adult Humans
2011
Human BAT Possesses Molecular Signatures That Resemble Beige/Brite Cells
2012
Cellular bioenergetics as a target for obesity therapy
2010
Ferroptosis: mechanisms, biology and role in disease
2021 Standout
The Hallmarks of Aging
2013 Standout
MicroRNA-133 Controls Brown Adipose Determination in Skeletal Muscle Satellite Cells by Targeting Prdm16
2013
Role of adipose specific lipid droplet proteins in maintaining whole body energy homeostasis
2013
EID1-induces brown-like adipocyte traits in white 3T3-L1 pre-adipocytes
2010
IRF4 Is a Key Thermogenic Transcriptional Partner of PGC-1α
2014
Transplantation of adipose tissue and stem cells: role in metabolism and disease
2010
FTO Obesity Variant Circuitry and Adipocyte Browning in Humans
2015
Studies Comparing Numerical Rating Scales, Verbal Rating Scales, and Visual Analogue Scales for Assessment of Pain Intensity in Adults: A Systematic Literature Review
2011 Standout
European Guidelines for Obesity Management in Adults
2015 Standout
Prediabetes: a high-risk state for diabetes development
2012 Standout
Using brown adipose tissue to treat obesity – the central issue
2011
PHD3 Loss in Cancer Enables Metabolic Reliance on Fatty Acid Oxidation via Deactivation of ACC2
2016 StandoutNobel
PD-L1 is an activation-independent marker of brown adipocytes
2017
Autophagy in immunity and inflammation
2011 StandoutNature
Forming functional fat: a growing understanding of adipocyte differentiation
2011
Sympathetic and sensory innervation of brown adipose tissue
2010
Bi-directional interconversion of brite and white adipocytes
2013
miR-133a Regulates Adipocyte Browning In Vivo
2013
Peptidic degron in EID1 is recognized by an SCF E3 ligase complex containing the orphan F-box protein FBXO21
2015 StandoutNobel
Brown Adipose Tissue in Adult Humans: A Metabolic Renaissance
2013
A Recurring Problem With the Analysis of Energy Expenditure in Genetic Models Expressing Lean and Obese Phenotypes
2010
C/EBPα and the Corepressors CtBP1 and CtBP2 Regulate Repression of Select Visceral White Adipose Genes during Induction of the Brown Phenotype in White Adipocytes by Peroxisome Proliferator-Activated Receptor γ Agonists
2009
Loss of Perivascular Adipose Tissue on Peroxisome Proliferator–Activated Receptor-γ Deletion in Smooth Muscle Cells Impairs Intravascular Thermoregulation and Enhances Atherosclerosis
2012
Brown Adipose Tissue Growth and Development
2013
GRK2 contribution to the regulation of energy expenditure and brown fat function
2012
Cold acclimation recruits human brown fat and increases nonshivering thermogenesis
2013
Genome-Wide Profiling of Peroxisome Proliferator-Activated Receptor γ in Primary Epididymal, Inguinal, and Brown Adipocytes Reveals Depot-Selective Binding Correlated with Gene Expression
2012
Hormone-induced mitochondrial fission is utilized by brown adipocytes as an amplification pathway for energy expenditure
2014
The emergence of cold-induced brown adipocytes in mouse white fat depots is determined predominantly by white to brown adipocyte transdifferentiation
2010
Importance of Assessing Cardiorespiratory Fitness in Clinical Practice: A Case for Fitness as a Clinical Vital Sign: A Scientific Statement From the American Heart Association
2016 Standout
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Adipocyte Pseudohypoxia Suppresses Lipolysis and Facilitates Benign Adipose Tissue Expansion
2014 StandoutNobel
Atg9 vesicles are an important membrane source during early steps of autophagosome formation
2012 StandoutNobel
Once-Weekly Semaglutide in Adults with Overweight or Obesity
2021 Standout
Beige differentiation of adipose depots in mice lacking prolactin receptor protects against high‐fat‐diet‐induced obesity
2012
Organ-Specific Physiological Responses to Acute Physical Exercise and Long-Term Training in Humans
2014
Cyclooxygenase-2 Controls Energy Homeostasis in Mice by de Novo Recruitment of Brown Adipocytes
2010 Science
Brown Fat Activation Mediates Cold-Induced Thermogenesis in Adult Humans in Response to a Mild Decrease in Ambient Temperature
2013
Dexmedetomidine: An Updated Review
2007
Autophagy and Metabolism
2010 StandoutScience
Implications of nonshivering thermogenesis for energy balance regulation in humans
2011
AMPK regulation of fatty acid metabolism and mitochondrial biogenesis: Implications for obesity
2012
Identification of inducible brown adipocyte progenitors residing in skeletal muscle and white fat
2010
Blockade of the Activin Receptor IIB Activates Functional Brown Adipogenesis and Thermogenesis by Inducing Mitochondrial Oxidative Metabolism
2012
Cardiovascular and Metabolic Heterogeneity of Obesity
2018
The Adipocyte-Expressed Forkhead Transcription Factor Foxc2 Regulates Metabolism Through Altered Mitochondrial Function
2011
Fat cells directly sense temperature to activate thermogenesis
2013
Uncoupling proteins: Martin Klingenberg's contributions for 40 years
2018
The Role of Atg Proteins in Autophagosome Formation
2011 StandoutNobel
Works of Markku Taittonen being referenced
Prostatectomy patients’ postoperative pain assessment in the recovery room
2005
Functional Brown Adipose Tissue in Healthy Adults
2009 Standout
Different Metabolic Responses of Human Brown Adipose Tissue to Activation by Cold and Insulin
2011
Effect of Caloric Restriction on Myocardial Fatty Acid Uptake, Left Ventricular Mass, and Cardiac Work in Obese Adults
2009
The Effect of Clonidine or Midazolam Premedication on Perioperative Responses During Ketamine Anesthesia
1998
Effect of clonidine and dexmedetomidine premedication on perioperative oxygen consumption and haemodynamic state
1997
Human obesity is characterized by defective fat storage and enhanced muscle fatty acid oxidation, and trimetazidine gradually counteracts these abnormalities
2011
The Effect of Clonidine or Midazolam Premedication on Perioperative Responses During Ketamine Anesthesia
1998