Citation Impact
Citing Papers
Oxidative Stress
2017 Standout
The Critical Role of the Class III Histone Deacetylase SIRT1 in Cancer
2009
Preclinical Development of the Novel Chk1 Inhibitor SCH900776 in Combination with DNA-Damaging Agents and Antimetabolites
2011
Reciprocal Regulation of DUSP9 and DUSP16 Expression by HIF1 Controls ERK and p38 MAP Kinase Activity and Mediates Chemotherapy-Induced Breast Cancer Stem Cell Enrichment
2018 StandoutNobel
Sirtuins as regulators of metabolism and healthspan
2012 Standout
Hydrogen peroxide sensing, signaling and regulation of transcription factors
2014
Reconsidering Movement of Eukaryotic mRNAs between Polysomes and P Bodies
2011 StandoutNobel
Expanded Roles for Chk1 in Genome Maintenance
2008
Hypoxia-Inducible Factors and the Response to Hypoxic Stress
2010 Standout
HuR-dependent loading of miRNA RISC to the mRNA encoding the Ras-related small GTPase RhoB controls its translation during UV-induced apoptosis
2011
Tipin-Replication Protein A Interaction Mediates Chk1 Phosphorylation by ATR in Response to Genotoxic Stress
2010 StandoutNobel
lincRNAs: Genomics, Evolution, and Mechanisms
2013 Standout
Exercise, redox homeostasis and the epigenetic landscape
2020
Resveratrol alleviates alcoholic fatty liver in mice
2008
LincRNA-p21 Suppresses Target mRNA Translation
2012
G2 checkpoint abrogation and checkpoint kinase-1 targeting in the treatment of cancer
2008
Diverse molecular functions of Hu proteins
2008
Double Strand Breaks Can Initiate Gene Silencing and SIRT1-Dependent Onset of DNA Methylation in an Exogenous Promoter CpG Island
2008
HIF-1: upstream and downstream of cancer metabolism
2009 StandoutNobel
The heat shock transcription factor Hsf1 is downregulated in DNA damage–associated senescence, contributing to the maintenance of senescence phenotype
2012
Deleted in breast cancer–1 regulates SIRT1 activity and contributes to high-fat diet–induced liver steatosis in mice
2010
The ATM–Chk2 and ATR–Chk1 Pathways in DNA Damage Signaling and Cancer
2010
Dopamine Transporters Participate in the Physiological Regulation of Prolactin1
2000
The ribonome: a dominant force in co‐ordinating gene expression
2009
Signal Transduction by the JNK Group of MAP Kinases
2000 Standout
Cell cycle proteins as promising targets in cancer therapy
2017 Standout
Sirtuin-7 Inhibits the Activity of Hypoxia-inducible Factors
2013 StandoutNobel
Smad transcription factors
2005 Standout
Cdk5rap2 exposes the centrosomal root of microcephaly syndromes
2011
Reconstitution of Human Claspin-mediated Phosphorylation of Chk1 by the ATR (Ataxia Telangiectasia-mutated and Rad3-related) Checkpoint Kinase
2009 StandoutNobel
The DNA Damage Response Kinases DNA-dependent Protein Kinase (DNA-PK) and Ataxia Telangiectasia Mutated (ATM) Are Stimulated by Bulky Adduct-containing DNA
2011 StandoutNobel
Cellular senescence in aging and age-related disease: from mechanisms to therapy
2015 Standout
TGF-β signaling in tumor suppression and cancer progression
2001 Standout
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
2014 StandoutNature
Genetic instability and mammary tumor formation in mice carrying mammary-specific disruption of Chk1 and p53
2010
The emerging role of lncRNAs in cancer
2015 Standout
The oncoprotein Evi-1 represses TGF-β signalling by inhibiting Smad3
1998 Nature
MCPH1 regulates the neuroprogenitor division mode by coupling the centrosomal cycle with mitotic entry through the Chk1–Cdc25 pathway
2011
Long Noncoding RNAs in Cancer Pathways
2016 Standout
Regulation of Translation Initiation in Eukaryotes: Mechanisms and Biological Targets
2009 Standout
RNA regulons: coordination of post-transcriptional events
2007
The multilayered complexity of ceRNA crosstalk and competition
2014 StandoutNature
Molecular mechanisms of cisplatin resistance
2011 Standout
RIBEYE, a Component of Synaptic Ribbons
2000 StandoutNobel
Negative regulation of inflammation by SIRT1
2012
Claspin is phosphorylated in the Chk1-binding domain by a kinase distinct from Chk1
2008
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
Proteomic Analysis of the Rat Ovary Following Chronic Low-Dose Exposure to 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD)
2009
Checkpoint control and cancer
2011
Long non-coding RNAs: new players in cell differentiation and development
2013 Standout
Cloning and characterization of mCtBP2, a co-repressor that associates with basic Kruppel-like factor and other mammalian transcriptional regulators
1998
The DNA Damage Response: Making It Safe to Play with Knives
2010 Standout
Human DNA damage response and repair deficiency syndromes: Linking genomic instability and cell cycle checkpoint proficiency
2009
Scaffold function of long non-coding RNA HOTAIR in protein ubiquitination
2013
Sirtuins: critical regulators at the crossroads between cancer and aging
2007
The role of the 3' untranslated region in post-transcriptional regulation of protein expression in mammalian cells.
2012
Intrinsically disordered proteins in cellular signalling and regulation
2014 Standout
Quantitative phosphoproteomics to unravel the cellular response to chemical stressors with different modes of action
2020
Functional Interplay between RNA-Binding Protein HuR and microRNAs
2012
The Evi-1 oncoprotein inhibits c-Jun N-terminal kinase and prevents stress-induced cell death
2000
Oxidative Stress in Cancer
2020 Standout
Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology
2022 Standout
The many roles of histone deacetylases in development and physiology: implications for disease and therapy
2008 Standout
Identification of RNA–protein interaction networks using PAR‐CLIP
2011
SirT1-null mice develop tumors at normal rates but are poorly protected by resveratrol
2009
Alcoholic Liver Disease: Pathogenesis and New Therapeutic Targets
2011 Standout
Cerebral organoids model human brain development and microcephaly
2013 StandoutNature
The Hallmarks of Aging
2013 Standout
Role of SIRT1 in regulation of LPS- or two ethanol metabolites-induced TNF-α production in cultured macrophage cell lines
2009
Transcriptome-wide Identification of RNA-Binding Protein and MicroRNA Target Sites by PAR-CLIP
2010 Standout
Recent lessons in gene expression, cell cycle control, and cell biology from adenovirus
2005
UDP-glucose accelerates SNAI1 mRNA decay and impairs lung cancer metastasis
2019 Nature
Sirtuin 1 Modulates Cellular Responses to Hypoxia by Deacetylating Hypoxia-Inducible Factor 1α
2010
Long Noncoding RNAs: Cellular Address Codes in Development and Disease
2013 Standout
NEW EMBO MEMBERS REVIEW: Transcriptional control by the TGF-beta/Smad signaling system
2000 Standout
Regulatory networks defining EMT during cancer initiation and progression
2013 Standout
Inhibition of Chk1 Kills Tetraploid Tumor Cells through a p53-Dependent Pathway
2007
Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction
2009 Standout
starBase v2.0: decoding miRNA-ceRNA, miRNA-ncRNA and protein–RNA interaction networks from large-scale CLIP-Seq data
2013 Standout
The Role of Sirtuins in Antioxidant and Redox Signaling
2017
New Insights into Checkpoint Kinase 1 in the DNA Damage Response Signaling Network
2010
RNA–protein analysis using a conditional CRISPR nuclease
2013 StandoutNobel
EDC-2: The Endocrine Society's Second Scientific Statement on Endocrine-Disrupting Chemicals
2015 Standout
MicroRNA profiling in human diploid fibroblasts uncovers miR-519 role in replicative senescence
2010
Long Noncoding RNA and Cancer: A New Paradigm
2017 Standout
Sirtuin 1 and Sirtuin 3: Physiological Modulators of Metabolism
2012
The corepressor CtBP interacts with Evi-1 to repress transforming growth factor β signaling
2001
Tissue- and age-dependent expression of RNA-binding proteins that influence mRNA turnover and translation
2009
Phase I Dose-Escalation Trial of Checkpoint Kinase 1 Inhibitor MK-8776 As Monotherapy and in Combination With Gemcitabine in Patients With Advanced Solid Tumors
2015
Senescence-associated lncRNAs: senescence-associated long noncoding RNAs
2013
In Vitro Analysis of the Role of Replication Protein A (RPA) and RPA Phosphorylation in ATR-mediated Checkpoint Signaling
2012 StandoutNobel
HDAC4, a Human Histone Deacetylase Related to Yeast HDA1, Is a Transcriptional Corepressor
1999
Prolactin: Structure, Function, and Regulation of Secretion
2000 Standout
Metabolic reprogramming and cancer progression
2020 StandoutScience
miRNAs regulate SIRT1 expression during mouse embryonic stem cell differentiation and in adult mouse tissues
2010 StandoutNobel
Cancer Genome Landscapes
2013 StandoutScience
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression
2012 StandoutNobel
Methylation of hypoxia-inducible factor (HIF)-1α by G9a/GLP inhibits HIF-1 transcriptional activity and cell migration
2018 StandoutNobel
Regulation of mRNA Translation and Stability by microRNAs
2010 Standout
Translational Control of TOP2A Influences Doxorubicin Efficacy
2011
RPA phosphorylation facilitates mitotic exit in response to mitotic DNA damage
2008
DNA Damage Detection and Repair Pathways—Recent Advances with Inhibitors of Checkpoint Kinases in Cancer Therapy
2008
Works of Mark Walker being referenced
Evi-1 Transforming and Repressor Activities Are Mediated by CtBP Co-repressor Proteins
2001
Cdk-mediated phosphorylation of Chk1 is required for efficient activation and full checkpoint proficiency in response to DNA damage
2011
The Evi-1 proto-oncogene encodes a transcriptional repressor activity associated with transformation
1997
Chk1 Is Required for Spindle Checkpoint Function
2007
Chk1 C-terminal regulatory phosphorylation mediates checkpoint activation by de-repression of Chk1 catalytic activity
2009
Different patterns of regulation of the genes encoding the closely related 56 kDa selenium- and acetaminophen-binding proteins in normal tissues and during carcinogenesis
1993
Phosphorylation of HuR by Chk2 Regulates SIRT1 Expression
2007
Chk1-dependent slowing of S-phase progression protects DT40 B-lymphoma cells against killing by the nucleoside analogue 5-fluorouracil
2006
DNA damage induces Chk1‐dependent centrosome amplification
2007
Further studies on the effects of intravenously administered 6-hydroxydopamine on the median eminence of the rat
1982