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Citing Papers
4-1BB and Ox40 Are Members of a Tumor Necrosis Factor (TNF)-Nerve Growth Factor Receptor Subfamily That Bind TNF Receptor-Associated Factors and Activate Nuclear Factor κB
1998
Immune Rejection of Mouse Tumors Expressing Mutated Self
2009 StandoutNobel
Hemocyanins
1995
Identification of a major co-receptor for primary isolates of HIV-1
1996 StandoutNature
Human tyrosinase gene, mapped to chromosome 11 (q14 → q21), defines second region of homology with mouse chromosome 7
1988 Nobel
Pigmentation phenotypes of variant extension locus alleles result from point mutations that alter MSH receptor function
1993
Structure-based design of irreversible, tripeptidyl human rhinovirus 3C protease inhibitors containing N-methyl amino acids
1999
Are L-tyrosine and L-dopa hormone-like bioregulators?
1990
The tyrosinase-related protein-1 gene has a structure and promoter sequence very different from tyrosinase
1991
Cell Death Mechanisms and the Immune System
1991
Mouse Chromosome 7
1992
Molecular imaging in living subjects: seeing fundamental biological processes in a new light
2003 Standout
Recent developments in asymmetric multicomponent reactions
2012
Leukocyte-endothelial cell recognition: Three (or more) steps to specificity and diversity
1991 Standout
Melanin Pigmentation in Mammalian Skin and Its Hormonal Regulation
2004 Standout
Unravelling hepatitis C virus replication from genome to function
2005 StandoutNatureNobel
Biology of the rantes/sis cytokine family
1991
Glucocorticoid Stimulates Melanogenesis and Tyrosinase Gene Expression in B16 Melanoma Cells
1991
Coexpression of Wild-Type Tyrosinase Enhances Maturation of Temperature-Sensitive Tyrosinase Mutants
2002
Tyrosinase isoenzymes in mammalian melanocytes
1993
Molecular cloning and expression of the fas ligand, a novel member of the tumor necrosis factor family
1993 Standout
Inhibition of Tyrosinase Reduces Cell Viability in Catecholaminergic Neuronal Cells
2000
An Evolutionary and Functional Approach to the TNF Receptor/Ligand Family
1994 StandoutNobel
Homozygous Defect in HIV-1 Coreceptor Accounts for Resistance of Some Multiply-Exposed Individuals to HIV-1 Infection
1996 Standout
Design, synthesis, and evaluation of azapeptides as substrates and inhibitors for human rhinovirus 3C protease
1999
A new serine-protease fold revealed by the crystal structure of human cytomegalovirus protease
1996 Nature
Targeted Disruption of the Melanocortin-4 Receptor Results in Obesity in Mice
1997 Standout
Production of POMC, CRH-R1, MC1, and MC2 Receptor mRNA and Expression of Tyrosinase Gene in Relation to Hair Cycle and Dexamethasone Treatment in the C57BL/6 Mouse Skin
1997
A highly efficient synthesis of telaprevir by strategic use of biocatalysis and multicomponent reactions
2010
The Regulatory Basis of Melanogenic Switching
2002
Chromosomal localization of seven members of the murine TGF-β superfamily suggests close linkage to several morphogenetic mutant loci
1990
Differential Expression and Activity of Melanogenesis-Related Proteins During Induced Hair Growth in Mice
1991
The 5,6-dihydroxyindole-2-carboxylic acid (DHICA) oxidase activity of human tyrosinase
2001
Identification and characterization of a new member of the TNF family that induces apoptosis
1995 Standout
Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair
1993 Standout
Three-dimensional structure of human cytomegalovirus protease
1996 Nature
4‐1BB T‐cell antigen binds to mature B cells and macrophages, and costimulates anti‐μ‐primed splenic B cells
1994
4-1BB (CD137) controls the clonal expansion and survival of CD8 T cellsin vivo but does not contribute to the development of cytotoxicity
2002
Induction of tyrosinase in human melanoma cells by l-tyrosine phosphate and cytochalasin D
1992
Regulation of mammalian melanogenesis by tyrosinase inhibition
1989
Highly Stereoselective Biocatalytic Synthesis of Key Cyclopropane Intermediate to Ticagrelor
2016 StandoutNobel
Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice
1994 StandoutNature
Hormonal stimulation of tyrosinase activity in human foreskin organ cultures
1990
Sequence and structural features of plant and fungal tyrosinases
1997
Biosynthesis and intracellular movement of the melanosomal membrane glycoprotein gp75, the human b (brown) locus product
1991
The TNF receptor superfamily of cellular and viral proteins: Activation, costimulation, and death
1994 Standout
Molecular mechanism of tyrosinase regulation by L-DOPA in hamster melanoma cells
1991
Molecular cloning of a ligand for the inducible T cell gene 4‐1BB: a member of an emerging family of cytokines with homology to tumor necrosis factor
1993
Perforin: structure and function
1995
The development of in vivo imaging systems to study gene expression
1998
Structure of the zinc-binding domain of an essential component of the hepatitis C virus replicase
2005 StandoutNatureNobel
Targeted and natural (piebald-lethal) mutations of endothelin-B receptor gene produce megacolon associated with spotted coat color in mice
1994 Standout
Mouse coat colour mutations: A molecular genetic resource which spans the centuries
1991
L-tyrosine induces tyrosinase expression via a posttranscriptional mechanism
1991
Ultraviolet B Radiation Acts through the Nitric Oxide and cGMP Signal Transduction Pathway to Stimulate Melanogenesis in Human Melanocytes
1996
Constitutive activity of receptors coupled to guanine nucleotide regulatory proteins
1993 StandoutNobel
High-Molecular-Weight Forms of Tyrosinase and the Tyrosinase-Related Proteins: Evidence for a Melanogenic Complex
1994
The molecular basis of brown, an old mouse mutation, and of an induced revertant to wild type.
1990
Structure of the Human Cytomegalovirus Protease Catalytic Domain Reveals a Novel Serine Protease Fold and Catalytic Triad
1996
Mechanisms of Ultraviolet Light‐Induced Pigmentation
1996
Unique fold and active site in cytomegalovirus protease
1996 Nature
Tyrosinase maturation through the mammalian secretory pathway: bringing color to life
2006
Multicomponent Reaction Design in the Quest for Molecular Complexity and Diversity
2011 Standout
The way forward in HCV treatment — finding the right path
2007 StandoutNobel
Transmembrane Regions V and VI of the Human Luteinizing Hormone Receptor Are Required for Constitutive Activation by a Mutation in the Third Intracellular Loop
1996 StandoutNobel
Replication of hepatitis C virus
2007 StandoutNobel
Structural Instability of a Constitutively Active G Protein-coupled Receptor
1997 StandoutNobel
Tyrosinases from two different loci are expressed by normal and by transformed melanocytes.
1991
Costimulation via Glucocorticoid-Induced TNF Receptor in Both Conventional and CD25+ Regulatory CD4+ T Cells
2004 StandoutNobel
Molecular Recognition of Protein−Ligand Complexes: Applications to Drug Design
1997 Standout
Discovery and Structure−Activity Relationship of P1−P3 Ketoamide Derived Macrocyclic Inhibitors of Hepatitis C Virus NS3 Protease
2008
Prostanoid Receptors: Structures, Properties, and Functions
1999 Standout
Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death.
1992 StandoutNobel
cDNA sequences of two inducible T-cell genes.
1989
Multicopper Oxidases and Oxygenases
1996 Standout
Copper transfer and activation of the Streptomyces apotyrosinase are mediated through a complex formation between apotyrosinase and its trans-activator MelC1.
1992
Copper Active Sites in Biology
2014 Standout
Role of 4-1BB ligand in costimulation of T lymphocyte growth and its upregulation on M12 B lymphomas by cAMP.
1995
A second tyrosinase-related protein, TRP-2, maps to and is mutated at the mouse slaty locus.
1992
Nitric oxide and the immune response
2001 Standout
In Vitro Antiviral Activity of AG7088, a Potent Inhibitor of Human Rhinovirus 3C Protease
1999
Fas transduces activation signals in normal human T lymphocytes.
1993 StandoutNobel
Substituted Benzamide Inhibitors of Human Rhinovirus 3C Protease: Structure-Based Design, Synthesis, and Biological Evaluation
2000
Identification of RANTES, MIP-1α, and MIP-1β as the Major HIV-Suppressive Factors Produced by CD8 + T Cells
1995 StandoutScience
Recent advances in the synthesis of pyrroles by multicomponent reactions
2014 Standout
Tripeptide Aldehyde Inhibitors of Human Rhinovirus 3C Protease: Design, Synthesis, Biological Evaluation, and Cocrystal Structure Solution of P1 Glutamine Isosteric Replacements
1998
Isolation and Characterization of the Tyrosinase Gene from Neurospora crassa
1989
Oligomerization and Cooperative RNA Synthesis Activity of Hepatitis C Virus RNA-Dependent RNA Polymerase
2002
Synthetic approaches to the 2011 new drugs
2013
Stereoselective Enzymatic Synthesis of Heteroatom-Substituted Cyclopropanes
2018 StandoutNobel
Fundamental Mechanisms of Immune Checkpoint Blockade Therapy
2018 StandoutNobel
Enhancing and suppressing effects of recombinant murine macrophage inflammatory proteins on colony formation in vitro by bone marrow myeloid progenitor cells
1990
Studying Hepatitis C Virus: Making the Best of a Bad Virus
2007 StandoutNobel
Pigmentation Genes: the Tyrosinase Gene Family and the pmel 17 Gene Family
1993
Recent applications of multicomponent reactions in medicinal chemistry
2012
Murine and human b locus pigmentation genes encode a glycoprotein (gp75) with catalase activity.
1990
Synthesis and Evaluation of Peptidyl Michael Acceptors That Inactivate Human Rhinovirus 3C Protease and Inhibit Virus Replication
1998
A new enzymatic function in the melanogenic pathway. The 5,6-dihydroxyindole-2-carboxylic acid oxidase activity of tyrosinase-related protein-1 (TRP1).
1994
Absence of Macrophage Inflammatory Protein-1α Prevents the Development of Blinding Herpes Stromal Keratitis
1998 StandoutNobel
Signal Sequence Trap: a Cloning Strategy for Secreted Proteins and Type I Membrane Proteins
1993 StandoutScienceNobel
Endoplasmic reticulum retention is a common defect associated with tyrosinase-negative albinism
2000
Hepatitis C Virus RNA Synthesis in a Cell-Free System Isolated from Replicon-Containing Hepatoma Cells
2003 StandoutNobel
Design, Synthesis, and Evaluation of Oxygen-Containing Macrocyclic Peptidomimetics as Inhibitors of HCV NS3 Protease
2009
Seppuku and Autoimmunity
1992 StandoutScienceNobel
Cloning, expression, and chromosomal localization of beta-adrenergic receptor kinase 2. A new member of the receptor kinase family
1991 StandoutNobel
Conversion of Alloantigen-Specific CD8+ T Cell Anergy to CD8+ T Cell Priming through In Vivo Ligation of Glucocorticoid-Induced TNF Receptor
2006 StandoutNobel
Review HCV Antiviral Resistance: The Impact of in vitro Studies on the Development of Antiviral Agents Targeting the Viral NS5B Polymerase
2005
Enzymatic control of pigmentation in mammals
1991
The “Cyclopropyl Fragment” is a Versatile Player that Frequently Appears in Preclinical/Clinical Drug Molecules
2016
The Combinatorial Synthesis of Bicyclic Privileged Structures or Privileged Substructures
2003 Standout
Structural organization of the pigment cell-specific gene located at the brown locus in mouse. Its promoter activity and alternatively spliced transcript
1991
Ab Initio Evaluation of the Free Energy Surfaces for the General Base/Acid Catalyzed Thiolysis of Formamide and the Hydrolysis of Methyl Thiolformate: A Reference Solution Reaction for Studies of Cysteine Proteases
2001 StandoutNobel
Structure-assisted design of mechanism-based irreversible inhibitors of human rhinovirus 3C protease with potent antiviral activity against multiple rhinovirus serotypes
1999
Viral Proteases
2002
Antagonism of Central Melanocortin Receptors in Vitro and in Vivo by Agouti-Related Protein
1997 StandoutScience
Structure-Based Design of a Parallel Synthetic Array Directed Toward the Discovery of Irreversible Inhibitors of Human Rhinovirus 3C Protease
2002
Nitric Oxide Synthase-2 and Expression of Perforin in Uterine NK Cells
2000
Molecular basis for the heterogeneity of human tyrosinase.
1988
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
Mutations Conferring Resistance to a Hepatitis C Virus (HCV) RNA-Dependent RNA Polymerase Inhibitor Alone or in Combination with an HCV Serine Protease Inhibitor In Vitro
2005
The Cytolytic P 2Z Receptor for Extracellular ATP Identified as a P 2X Receptor (P2X 7 )
1996 StandoutScience
Azodicarboxamides: A New Class of Cysteine Proteinase Inhibitor for Hepatitis A Virus and Human Rhinovirus 3C Enzymes
1999
Cloning of the human DOPAchrome tautomerase/tyrosinase-related protein 2 gene and identification of two regulatory regions required for its pigment cell-specific expression.
1994
Irreversible Inhibitors of Serine, Cysteine, and Threonine Proteases
2002 Standout
Template Requirements for RNA Synthesis by a Recombinant Hepatitis C Virus RNA-Dependent RNA Polymerase
2000
Mechanisms and Genes of Cellular Suicide
1995 StandoutScience
Genomic organization of the mouse pore-forming protein (perforin) gene and localization to chromosome 10. Similarities to and differences from C9.
1990
Metal-Free Multicomponent Syntheses of Pyridines
2014 Standout
Recent advances in the development of human rhinovirus 3C protease inhibitors
2001
Works of Mark Wakulchik being referenced
Discovery of a novel bicycloproline P2 bearing peptidyl α-ketoamide LY514962 as HCV protease inhibitor
2003
Specificity and Mechanism Analysis of Hepatitis C Virus RNA-Dependent RNA Polymerase
2000
The structure of the mouse lymphocyte pore-forming protein perforin
1989
Sequence analysis of mouse tyrosinase cDNA and the effect of melanotropin on its gene expression
1988
Identification and Characterization of Human Rhinovirus-14 3C Protease Deamidation Isoform
1999
Isolation, Chromosomal Mapping, and Expression of the Mouse Tyrosinase Gene
1989 Nobel
Expression and Purification of Recombinant Rhinovirus 14 3CD Proteinase and Its Comparison to the 3C Proteinase
1997
P4 and P1′ optimization of bicycloproline P2 bearing tetrapeptidyl α-ketoamides as HCV protease inhibitors
2004
Expression characteristics of two potential T cell mediator genes
1989
Isolation and sequence analysis of serine protease cDNAs from mouse cytolytic T lymphocytes.
1988
Small peptidic aldehyde inhibitors of human rhinovirus 3C protease
1996
Human cytomegalovirus proteinase: candidate glutamic acid identified as third member of putative active-site triad
1995
Inhibition of human rhinovirus 3C protease by homophthalimides
1997
Human cytomegalovirus maturational proteinase: expression in Escherichia coli, purification, and enzymatic characterization by using peptide substrate mimics of natural cleavage sites
1994