Citation Impact

Citing Papers

Directed evolution of the tryptophan synthase β-subunit for stand-alone function recapitulates allosteric activation
2015 StandoutNobel
Olefin Cyclopropanation via Carbene Transfer Catalyzed by Engineered Cytochrome P450 Enzymes
2012 StandoutScienceNobel
The re-emergence of natural products for drug discovery in the genomics era
2015 Standout
Small-Molecule Inhibitors of the p53-MDM2 Interaction
2010
Regioselective C–H bond functionalizations of acridines using organozinc reagents
2011
Ferroptosis as a p53-mediated activity during tumour suppression
2015 StandoutNature
PKS and NRPS release mechanisms
2009
Small‐Molecule Affinity Ligands for Protein Purification: Combined Computational Enrichment and Automated In‐line Screening of an Optically Encoded Library
2010 StandoutNobel
Inhibition of α-helix-mediated protein–protein interactions using designed molecules
2013
Evolving Strategies for Protein Synthesis Converge on Native Chemical Ligation
2006 StandoutNobel
Targeting protein–protein interactions: Lessons from p53/MDM2
2007
Crystal structures of Λ-[Ru(phen)2dppz]2+ with oligonucleotides containing TA/TA and AT/AT steps show two intercalation modes
2012
A Computationally Designed Inhibitor of an Epstein-Barr Viral Bcl-2 Protein Induces Apoptosis in Infected Cells
2014 StandoutNobel
Oxidative Geminal Functionalization of Organoboron Compounds
2012
Gated Electron Sharing Within Dynamic Naphthalene Diimide‐Based Oligorotaxanes
2014 StandoutNobel
Improved Cyclopropanation Activity of Histidine‐Ligated Cytochrome P450 Enables the Enantioselective Formal Synthesis of Levomilnacipran
2014 StandoutNobel
Synthetic approaches to DNMT inhibitor SGI-1027 and effects on the U937 leukemia cell line
2013
The Organocatalytic Asymmetric Prins Cyclization
2015 StandoutNobel
Antimitotic and cell growth inhibitory properties of combretastatin A-4-like ethers
2001
Click Chemistry for Drug Development and Diverse Chemical–Biology Applications
2013 Standout
Copper-Mediated Coupling Reactions and Their Applications in Natural Products and Designed Biomolecules Synthesis
2008 Standout
3d Transition Metals for C–H Activation
2018 Standout
SuFEx Click Chemistry Enabled Late-Stage Drug Functionalization
2018 StandoutNobel
Biologically active quinoline and quinazoline alkaloids part I
2017
Supramolecular Coordination: Self-Assembly of Finite Two- and Three-Dimensional Ensembles
2011 Standout
Dynamical Contributions to Enzyme Catalysis:  Critical Tests of A Popular Hypothesis
2006 StandoutNobel
Photoexpulsion of Surface-Grafted Ruthenium Complexes and Subsequent Release of Cytotoxic Cargos to Cancer Cells from Mesoporous Silica Nanoparticles
2013 StandoutNobel
Assembly of Four Diverse Heterocyclic Libraries Enabled by Prins Cyclization, Au-Catalyzed Enyne Cycloisomerization, and Automated Amide Synthesis
2012
Structure determination of an intercalating ruthenium dipyridophenazine complex which kinks DNA by semiintercalation of a tetraazaphenanthrene ligand
2011
A novel heterometal–organic coordination polymer with chelidamic acid: nonlinear optical and magnetic properties,
2009
Multidimensional SuFEx Click Chemistry: Sequential Sulfur(VI) Fluoride Exchange Connections of Diverse Modules Launched From An SOF4 Hub
2017 StandoutNobel
Two Novel Metal−Organic Frameworks (MOFs) with (3,6)-Connected Net Topologies: Syntheses, Crystal Structures, Third-Order Nonlinear Optical and Luminescent Properties
2010
A General Catalytic Asymmetric Prins Cyclization
2016 StandoutNobel
Hydroamination: Direct Addition of Amines to Alkenes and Alkynes
2008 Standout
Cooperative capture synthesis: yet another playground for copper-free click chemistry
2016 StandoutNobel
The Hitchhiker’s Guide to Flow Chemistry
2017 Standout
G‐Quadruplex DNA Structures and Organic Chemistry: More Than One Connection
2009
Synthesis and Functionalization of Indoles Through Palladium-catalyzed Reactions
2005 Standout
Homologation of the Fischer Indolization: A Quinoline Synthesis via Homo‐Diaza‐Cope Rearrangement
2020 StandoutNobel
Apparent NAC Effect in Chorismate Mutase Reflects Electrostatic Transition State Stabilization
2003 StandoutNobel
Recent developments in indole ring synthesis—methodology and applications
2000 Standout
The Sonogashira Reaction:  A Booming Methodology in Synthetic Organic Chemistry
2007 Standout
A Novel, Unusually Efficacious Duocarmycin Carbamate Prodrug That Releases No Residual Byproduct
2012
Dynamic Combinatorial Chemistry
2006 Standout
Folding of Oligoviologens Induced by Radical–Radical Interactions
2014 StandoutNobel
Immune Versus Natural Selection: Antibody Aldolases with Enzymic Rates But Broader Scope
1997 StandoutScienceNobel
Metallo‐Controlled Dynamic Molecular Tweezers: Design, Synthesis, and Self‐Assembly by Metal‐Ion Coordination
2010 Nobel
Catalytic Dehydrogenative Cross-Coupling: Forming Carbon−Carbon Bonds by Oxidizing Two Carbon−Hydrogen Bonds
2011 Standout
Stereoselective Cyclopropanation Reactions
2003 Standout
Luminescent Functional Metal–Organic Frameworks
2011 Standout
De novo design of covalently constrained mesosize protein scaffolds with unique tertiary structures
2017 StandoutNobel
Enzymatic Chemistry of Cyclopropane, Epoxide, and Aziridine Biosynthesis
2011
Enzymatic construction of highly strained carbocycles
2018 StandoutScienceNobel
A Field Guide to Foldamers
2001 Standout
Supramolecular Helical Systems: Helical Assemblies of Small Molecules, Foldamers, and Polymers with Chiral Amplification and Their Functions
2016 Standout
Aromatic Amide Foldamers: Structures, Properties, and Functions
2012
Artificial Molecular Machines
2015 Standout
Trapping a transition state in a computationally designed protein bottle
2015 StandoutScienceNobel
Native Chemical Ligation through in Situ O to S Acyl Shift
2004
Binding Energy and Catalysis:  The Implications for Transition-State Analogs and Catalytic Antibodies
1997
From Molecular Diversity to Catalysis: Lessons from the Immune System
1995 Science
Large-Scale Applications of Transition Metal-Catalyzed Couplings for the Synthesis of Pharmaceuticals
2011 Standout
Electrostatic Basis for Enzyme Catalysis
2006 StandoutNobel
Chemomimetic Biocatalysis: Exploiting the Synthetic Potential of Cofactor-Dependent Enzymes To Create New Catalysts
2015 StandoutNobel
Advances in Synthetic Applications of Hypervalent Iodine Compounds
2016 Standout
Diversity Oriented Clicking (DOC): Divergent Synthesis of SuFExable Pharmacophores from 2‐Substituted‐Alkynyl‐1‐Sulfonyl Fluoride (SASF) Hubs
2020 StandoutNobel
Fluorosulfuryl Isocyanate Enabled SuFEx Ligation of Alcohols and Amines
2021 StandoutNobel
Mechanical Bonds and Topological Effects in Radical Dimer Stabilization
2014 StandoutNobel
Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
2016 Standout
Copper-Catalyzed Enantioselective Synthesis of trans-1-Alkyl-2-substituted Cyclopropanes via Tandem Conjugate Addition−Intramolecular Enolate Trapping
2010 StandoutNobel
Constrained Peptides as Miniature Protein Structures
2012
Threading Polyintercalators with Extremely Slow Dissociation Rates and Extended DNA Binding Sites
2013
The Catalytic Asymmetric Fischer Indolization
2011 StandoutNobel
Multiple event activation of a generic prodrug trigger by antibody catalysis
1999 StandoutNobel
Shape-Dependent Catalysis:  Insights into the Source of Catalysis for the CC-1065 and Duocarmycin DNA Alkylation Reaction
1999
Catalytic Asymmetric Vinylogous Prins Cyclization: A Highly Diastereo- and Enantioselective Entry to Tetrahydrofurans
2016 StandoutNobel

Works of Mark Searcey being referenced

Synthesis and evaluation of 9-aminoacridines derived from benzyne click chemistry
2009
Duocarmycins - Natures Prodrugs?
2002
X-ray crystallographic study of DNA duplex cross-linking: simultaneous binding to two d(CGTACG)2 molecules by a bis(9-aminoacridine-4-carboxamide) derivative
2006
Synthesis of distamycin A polyamides targeting G-quadruplex DNA
2006
Ligand Bridging of the DNA Holliday Junction: Molecular Recognition of a Stacked‐X Four‐Way Junction by a Small Molecule
2007
Design and synthesis of threading intercalators to target DNA
2010
The isolation, total synthesis and structure elucidation of chlorofusin, a natural product inhibitor of the p53–MDM2 protein–protein interaction
2009
Bisintercalator natural products with potential therapeutic applications: isolation, structure determination, synthetic and biological studies
2006
Catalytic antibody activity elicited by active immunisation
1993
Critical Role of the Linking Amide in CC-1065 and the Duocarmycins:  Implications on the Source of DNA Alkylation Catalysis
1998
Design, Synthesis, and Evaluation of an α-Helix Mimetic Library Targeting Protein−Protein Interactions
2009
Synthesis of CC-1065 and duocarmycin analogs via intramolecular aryl radical cyclization of a tethered vinyl chloride
1998
Ligand Bridging of the DNA Holliday Junction: Molecular Recognition of a Stacked‐X Four‐Way Junction by a Small Molecule
2007
Synthesis and Evaluation of 1,2,8,8a-Tetrahydrocyclopropa[c]pyrrolo[3,2-e]indol-4(5H)-one, the Parent Alkylation Subunit of CC-1065 and the Duocarmycins:  Impact of the Alkylation Subunit Substituents and Its Implications for DNA Alkylation Catalysis
2000
Total Synthesis and Comparative Evaluation of Luzopeptin A−C and Quinoxapeptin A−C
1999
Polyclonal antibody-catalysed amide hydrolysis
1992
Synthesis and Evaluation of Duocarmycin and CC-1065 Analogues Containing Modifications in the Subunit Linking Amide
1999
Synthesis, DNA-cleaving properties and cytotoxicity of intercalating chelidamic acid derivatives.
1998
Solid-Phase Synthesis of the Cyclic Peptide Portion of Chlorofusin, an Inhibitor of p53-MDM2 Interactions
2003
Rankless by CCL
2026