Citation Impact
Citing Papers
Insulin Resistance and a Diabetes Mellitus-Like Syndrome in Mice Lacking the Protein Kinase Akt2 (PKBβ)
2001 StandoutScience
Molecular Dissection of Formation of Senescence-Associated Heterochromatin Foci
2007
Genome-Wide Mapping of in Vivo Protein-DNA Interactions
2007 StandoutScience
BRCT Repeats As Phosphopeptide-Binding Modules Involved in Protein Targeting
2003 Science
The homeobox gene Phox2b is essential for the development of autonomic neural crest derivatives
1999 StandoutNature
An integrated encyclopedia of DNA elements in the human genome
2012 StandoutNature
The DNA-damage response in human biology and disease
2009 StandoutNature
Sequence-specific DNA binding by p53: identification of target sites and lack of binding to p53 - MDM2 complexes.
1993
Human papillomavirus 16 E6 expression disrupts the p53-mediated cellular response to DNA damage.
1993
Mdm2 promotes the rapid degradation of p53
1997 StandoutNature
Inflammation and cancer
2002 StandoutNature
KRAB–Zinc Finger Proteins and KAP1 Can Mediate Long-Range Transcriptional Repression through Heterochromatin Spreading
2010
Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein
1999 StandoutNature
Regulation of p53 stability by Mdm2
1997 StandoutNature
Cellular responses of HPV-positive cancer cells to genotoxic anti-cancer agents: Repression ofE6/E7-oncogene expression and induction of apoptosis
1996
WAF1, a potential mediator of p53 tumor suppression
1993 Standout
GFRα1-Deficient Mice Have Deficits in the Enteric Nervous System and Kidneys
1998
p53 in growth control and neoplasia
1996
Human papillomavirus oncoproteins: pathways to transformation
2010 Standout
Chromatin Modifications and Their Function
2007 Standout
Oncogenic kinase signalling
2001 StandoutNature
Epigenetics in human disease and prospects for epigenetic therapy
2004 StandoutNature
Cell-cycle checkpoints and cancer
2004 StandoutNature
The Role of POU Domain Proteins in the Regulation of Mammalian Pituitary and Nervous System Development
1999
Specific repression of TATA-mediated but not initiator-mediated transcription by wild-type p53
1993 Nature
p53, the Cellular Gatekeeper for Growth and Division
1997 Standout
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins
2002
G9a-mediated irreversible epigenetic inactivation of Oct-3/4 during early embryogenesis
2006
Renal‐coloboma syndrome: a multi‐system developmental disorder caused by PAX2 mutations
1999
Chromatin relaxation in response to DNA double-strand breaks is modulated by a novel ATM- and KAP-1 dependent pathway
2006
A Maternal-Zygotic Effect Gene, Zfp57, Maintains Both Maternal and Paternal Imprints
2008
The role of the E6-p53 interaction in the molecular pathogenesis of HPV
1999
DNA methylation: roles in mammalian development
2013 Standout
SetDB1 contributes to repression of genes encoding developmental regulators and maintenance of ES cell state
2009
Human papillomavirus 16 E6 oncoprotein binds to interferon regulatory factor-3 and inhibits its transcriptional activity
1998
The Krüppel-associated Box Repressor Domain Can Trigger de Novo Promoter Methylation during Mouse Early Embryogenesis
2007
Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions
2008 StandoutNature
The complex language of chromatin regulation during transcription
2007 StandoutNature
Nuclear factor-κB in cancer development and progression
2006 StandoutNature
Papillomaviruses and cancer: from basic studies to clinical application
2002 StandoutNobel
Intrinsic Immunity Shapes Viral Resistance of Stem Cells
2017 StandoutNobel
The RET proto-oncogene in human cancers
2000
Molecular Pathogenesis of Cancer of the Cervix and Its Causation by Specific Human Papillomavirus Types
1994 StandoutNobel
Papillomavirus E6 proteins
2008
A comprehensive catalog of human KRAB-associated zinc finger genes: Insights into the evolutionary history of a large family of transcriptional repressors
2006
Limb and kidney defects in Lmx1b mutant mice suggest an involvement of LMX1B in human nail patella syndrome
1998
Polycomb complexes repress developmental regulators in murine embryonic stem cells
2006 StandoutNature
Genome-Wide Analysis of KAP1 Binding Suggests Autoregulation of KRAB-ZNFs
2007
Disrupted dichotomous intracellular control of human papillomavirus infection in cancer of the cervix
1994 StandoutNobel
The DNA damage response: putting checkpoints in perspective
2000 StandoutNature
p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development
1999 StandoutNature
Active recruitment of DNA methyltransferases regulates interleukin 4 in thymocytes and T cells
2003
The role of senescent cells in ageing
2014 StandoutNature
Histone H3 Lysine 9 Methylation and HP1γ Are Associated with Transcription Elongation through Mammalian Chromatin
2005
TRIM28 Mediates Primer Binding Site-Targeted Silencing of Murine Leukemia Virus in Embryonic Cells
2007
Infections as a major preventable cause of human cancer
2000
CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes
2013 StandoutNobel
From Silencing to Gene Expression
2004
Embryonic stem cells use ZFP809 to silence retroviral DNAs
2009 Nature
Topological domains in mammalian genomes identified by analysis of chromatin interactions
2012 StandoutNature
Binary switches and modification cassettes in histone biology and beyond
2003 Nature
lincRNAs act in the circuitry controlling pluripotency and differentiation
2011 StandoutNature
Linking the epigenetic ‘language’ of covalent histone modifications to cancer
2004
Quantitative analysis of the activation mechanism of the multicomponent growth-factor receptor Ret
2006
The cancer genome
2009 StandoutNature
Eset partners with Oct4 to restrict extraembryonic trophoblast lineage potential in embryonic stem cells
2009
CHD7 cooperates with PBAF to control multipotent neural crest formation
2010 StandoutNature
The Role of E6AP in the Regulation of p53 Protein Levels in Human Papillomavirus (HPV)-positive and HPV-negative Cells
1998
Specific loss of apoptotic but not cell-cycle arrest function in a human tumor derived p53 mutant.
1996
Activity of the Caenorhabditis elegans UNC-86 POU transcription factor modulates olfactory sensitivity
2003 StandoutNobel
Regulation of Neurotrophin-3 Expression by Epithelial-Mesenchymal Interactions: The Role of Wnt Factors
1999 StandoutScienceNobel
Complete switch from Mdm2 to human papillomavirus E6-mediated degradation of p53 in cervical cancer cells
2001 StandoutNobel
Wnt-4 is a mesenchymal signal for epithelial transformation of metanephric mesenchyme in the developing kidney
1998
Retroviral Insertion Mutagenesis in Mice as a Comparative Oncogenomics Tool to Identify Disease Genes in Human Leukemia
2006
High-risk human papillomavirus E6 protein has two distinct binding sites within p53, of which only one determines degradation
1996
Growth arrest by induction of p53 in DNA damaged keratinocytes is bypassed by human papillomavirus 16 E7.
1994
Cancer Cell Cycles
1996 StandoutScience
Targeted Mutagenesis of the POU-Domain GeneBrn4/Pou3f4Causes Developmental Defects in the Inner Ear
1999
Reconstructing the DNA Methylation Maps of the Neandertal and the Denisovan
2014 StandoutScienceNobel
Cell Cycle Control and Cancer
1994 StandoutScienceNobel
Molecular mechanisms of E2F-dependent activation and pRB-mediated repression
2004
Differentiation-dependent up-regulation of the human papillomavirus E7 gene reactivates cellular DNA replication in suprabasal differentiated keratinocytes.
1995
Human Papillomavirus Type 16 E7 Maintains Elevated Levels of the cdc25A Tyrosine Phosphatase during Deregulation of Cell Cycle Arrest
2002
Regulation of p53 Function and Stability by Phosphorylation
1999
Uses for JNK: the Many and Varied Substrates of the c-Jun N-Terminal Kinases
2006
The mdm-2 oncogene can overcome wild-type p53 suppression of transformed cell growth.
1993
mdm2 expression is induced by wild type p53 activity.
1993
A comparison of the biological activities of wild‐type and mutant p53
1993
Antioxidant-induced changes of the AP-1 transcription complex are paralleled by a selective suppression of human papillomavirus transcription
1997 StandoutNobel
Unique potential of 4-1BB agonist antibody to promote durable regression of HPV + tumors when combined with an E6/E7 peptide vaccine
2015 StandoutNobel
Glial cell line-derived neurotrophic factor-dependent RET activation can be mediated by two different cell-surface accessory proteins
1997
ATM and ATR Substrate Analysis Reveals Extensive Protein Networks Responsive to DNA Damage
2007 StandoutScience
Multiple Functions of Human Papillomavirus Type 16 E6 Contribute to the Immortalization of Mammary Epithelial Cells
1999
Characterization of somatic cell nuclear reprogramming by oocytes in which a linker histone is required for pluripotency gene reactivation
2010 StandoutNobel
Papillomavirus E6 and E7 proteins and their cellular targets
2007
Interaction of Papillomavirus E6 Oncoproteins with a Putative Calcium-Binding Protein
1995 Science
Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis.
1994 StandoutNobel
Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B.
1993
Human Papillomavirus Oncoproteins E6 and E7 Independently Abrogate the Mitotic Spindle Checkpoint
1998
c-Abl Regulates p53 Levels under Normal and Stress Conditions by Preventing Its Nuclear Export and Ubiquitination
2001 StandoutNobel
Coordinated repression of cell cycle genes by KDM5A and E2F4 during differentiation
2012 StandoutNobel
Control of Angiogenesis in Fibroblasts by p53 Regulation of Thrombospondin-1
1994 StandoutScience
The Human Papillomavirus Type 16 E6 Oncoprotein Can Down-Regulate p53 Activity by Targeting the Transcriptional Coactivator CBP/p300
1999
Swift Is a Novel BRCT Domain Coactivator of Smad2 in Transforming Growth Factor β Signaling
2001 StandoutNobel
The WT1 gene product stabilizes p53 and inhibits p53-mediated apoptosis.
1995
Mechanisms and Genes of Cellular Suicide
1995 StandoutScience
JNK1 controls mast cell degranulation and IL-1β production in inflammatory arthritis
2010 StandoutNobel
Works of Mark S. Lechner being referenced
Mapping of Pax-2 Transcription Activation Domains
1996
Changes in the subcellular localization of the Brn4 gene product precede mesenchymal remodeling of the otic capsule
1998
The molecular basis of embryonic kidney development
1997
PTIP, a novel BRCT domain-containing protein interacts with Pax2 and is associated with active chromatin
2000
Phosphorylation of Pax2 by the c-Jun N-terminal Kinase and Enhanced Pax2-dependent Transcription Activation
2002
Human papillomavirus E6 proteins bind p53 in vivo and abrogate p53-mediated repression of transcription.
1992
Molecular Determinants for Targeting Heterochromatin Protein 1-Mediated Gene Silencing: Direct Chromoshadow Domain–KAP-1 Corepressor Interaction Is Essential
2000
Inhibition of p53 DNA binding by human papillomavirus E6 proteins
1994
Glial cell line-derived neurotrophic factor activates the receptor tyrosine kinase RET and promotes kidney morphogenesis.
1996
Regulated recruitment of HP1 to a euchromatic gene induces mitotically heritable, epigenetic gene silencing: a mammalian cell culture model of gene variegation
2003