Citation Impact
Citing Papers
High-throughput characterization of protein–protein interactions by reprogramming yeast mating
2017 StandoutNobel
The Rag GTPases Bind Raptor and Mediate Amino Acid Signaling to mTORC1
2008 StandoutScience
Tiagabine
1998
Structure and Function of Leukocyte Integrins
1990
Mechanism of activation of the TGF-β receptor
1994 StandoutNature
The Protein Kinase Family: Conserved Features and Deduced Phylogeny of the Catalytic Domains
1988 StandoutScience
S. cerevisiae α pheromone receptors activate a novel signal transduction pathway for mating partner discrimination
1991 StandoutNobel
Molecular cloning of the human α6 integrin subunit
1991
Developmentally regulated alternative splicing of Drosophila integrin PS2 α transcripts
1989
Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction
1995 StandoutNature
Crystal structure of the A domain from the a subunit of integrin CR3 (CD11 b/CD18)
1995
Myb DNA binding inhibited by phosphorylation at a site deleted during oncogenic activation
1990 StandoutNatureNobel
Courtship in S. cerevisiae: Both cell types choose mating partners by responding to the strongest pheromone signal
1990 StandoutNobel
Point mutations impairing cell surface expression of the common beta subunit (CD18) in a patient with leukocyte adhesion molecule (Leu-CAM) deficiency.
1990
Transfection of cells from patients with leukocyte adhesion deficiency with an integrin beta subunit (CD18) restores lymphocyte function-associated antigen-1 expression and function.
1990
Roles of the AMP‐activated and cyclic‐AMP‐dependent protein kinases in the adrenaline‐induced inactivation of acetyl‐CoA carboxylase in rat adipocytes
1990
Central nervous system control of food intake
2000 StandoutNature
The Leukocyte Integrins
1989
Mitosis-specific phosphorylation of p60c-src by p34cdc2-associated protein kinase
1989 StandoutNobel
Integrin cytoplasmic domains: mediators of cytoskeletal linkages and extra- and intracellular initiated transmembrane signaling
1993
Adhesion receptors of the immune system
1990 StandoutNature
Long-term potentiation in the hippocampus is blocked by tyrosine kinase inhibitors
1991 StandoutNatureNobel
FMRFamide reverses protein phosphorylation produced by 5-HT and cAMP in Aplysia sensory neurons
1989 StandoutNatureNobel
Membrane Proteins Involved in Phagocyte Adherence to Endothelium
1990
staufen, a gene required to localize maternal RNAs in the Drosophila egg
1991 StandoutNobel
Crystal structure of the tyrosine kinase domain of the human insulin receptor
1994 Nature
bottleneck acts as a regulator of the microfilament network governing cellularization of the Drosophila embryo
1993 StandoutNobel
Integrins
2002 Standout
The pathogenesis of atherosclerosis: a perspective for the 1990s
1993 StandoutNature
Insulin Action and the Insulin Signaling Network*
1995
An Isoleucine-based Allosteric Switch Controls Affinity and Shape Shifting in Integrin CD11b A-domain
2000
Organization of the gene for platelet glycoprotein IIb
1990
Identification of a murine Peyer's patch—specific lymphocyte homing receptor as an integrin molecule with an α chain homologous to human VLA-4α
1989
T Cell Activation Induces Rapid Tyrosine Phosphorylation of a Limited Number of Cellular Substrates
1989
Tyrosine-specific protein kinase activity is associated with the purified insulin receptor.
1983
Somatomedin-C stimulates the phosphorylation of the beta-subunit of its own receptor.
1983
CD45 regulates signal transduction and lymphocyte activation by specific association with receptor molecules on T or B cells.
1988 StandoutNobel
Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes
1985 StandoutNature
Phosphorylation of receptors for insulin and insulin-like growth factor I. Effects of hormones and phorbol esters.
1986
Regulation of Adhesion to ICAM-1 by the Cytoplasmic Domain of LFA-1 Integrin β Subunit
1991 Science
Distinct mutations in two patients with leukocyte adhesion deficiency and their functional correlates.
1990
ATP-stimulated interaction between epidermal growth factor receptor and supercoiled DNA
1984 StandoutNatureNobel
The biochemistry and physiology of the receptor-kinase for epidermal growth factor
1983
Mutation of the mouse klotho gene leads to a syndrome resembling ageing.
1997 Standout
Protein phosphotyrosine phosphatase purified from the particulate fraction of human placenta dephosphorylates insulin and growth-factor receptors
1988
Epithelial integrin alpha 6 beta 4: complete primary structure of alpha 6 and variant forms of beta 4.
1990
Leukocyte Adhesion Deficiency
1989
The primary structure of the alpha 4 subunit of VLA-4: homology to other integrins and a possible cell-cell adhesion function.
1989
Integrins: Versatility, modulation, and signaling in cell adhesion
1992 Standout
Calmodulin-stimulated phosphorylation of 17 beta-estradiol receptor on tyrosine.
1984
Protein kinases 1988: a current perspective
1988
Regulation of transmembrane signaling by receptor phosphorylation
1987 StandoutNobel
Role of glycosylation in the processing of newly translated insulin proreceptor in 3T3-L1 adipocytes.
1984
An endogenous substrate for the insulin receptor-associated tyrosine kinase.
1985
Phosphorylation/dephosphorylation of the beta-adrenergic receptor regulates its functional coupling to adenylate cyclase and subcellular distribution.
1986 StandoutNobel
Constitutive and stimulus-induced phosphorylation of CD11/CD18 leukocyte adhesion molecules.
1989
The Protein Phosphatases Involved in Cellular Regulation. 6. Measurement of Type-1 and Type-2 Protein Phosphatases in Extracts of Mammalian Tissues; an Assessment of Their Physiological Roles
1983
Impaired Long-Term Potentiation, Spatial Learning, and Hippocampal Development in fyn Mutant Mice
1992 StandoutScienceNobel
Use of an anti-insulin receptor antibody to discriminate between metabolic and mitogenic effects of insulin: correlation with receptor autophosphorylation.
1988
Identification of residues in the nucleotide binding site of the epidermal growth factor receptor/kinase.
1985 StandoutNobel
Phosphorylation activates the insulin receptor tyrosine protein kinase.
1983
Insulin: in search of a mechanism
1983
Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A
1986 StandoutNature
Selection of an RNA molecule that mimics a major autoantigenic epitope of human insulin receptor.
1995 StandoutNobel
Association of the VLA a Subunit with a Novel Protein
1989
Internalization-defective LDL receptors produced by genes with nonsense and frameshift mutations that truncate the cytoplasmic domain
1985 StandoutNobel
Isolation of a calcium-dependent 35-kilodalton substrate for the epidermal growth factor receptor/kinase from A-431 cells.
1984 StandoutNobel
After Insulin Binds
1987 Science
Characterization of insulin-like growth factor I-stimulated tyrosine kinase activity associated with the beta-subunit of type I insulin-like growth factor receptors of rat liver cells.
1985
Purification and characterization of the inducible a agglutinin of Saccharomyces cerevisiae.
1988
Phosphorylation of ribosomal protein S6 and a peptide analogue of S6 by a protease‐activated kinase isolated from rat liver
1984
Purification of the major protein-tyrosine-phosphatases of human placenta.
1988 StandoutNobel
Monoclonal Antibodies Mimic Insulin Activation of Ribosomal Protein S6 Kinase without Activation of Insulin Receptor Tyrosine Kinase
1989
Integrins and Signal Transduction Pathways: the Road Taken
1995 StandoutScience
AGα1 Is the Structural Gene for the Saccharomyces cerevisiae α-Agglutinin, a Cell Surface Glycoprotein Involved in Cell-Cell Interactions during Mating
1989
Identification of a cellular 110 000-Da protein substrate for the insulin-receptor kinase
1985
A comparison of the insulin- and epidermal growth factor-stimulated protein kinases from human placenta.
1984
Skeletal myoblasts utilize a novel beta 1-series integrin and not alpha 6 beta 1 for binding to the E8 and T8 fragments of laminin.
1991
Functionally homologous cell cycle control genes in budding and fission yeast
1982 StandoutNatureNobel
The AGA1 product is involved in cell surface attachment of the Saccharomyces cerevisiae cell adhesion glycoprotein a-agglutinin.
1991
The primary structure of the VLA-2/collagen receptor alpha 2 subunit (platelet GPIa): homology to other integrins and the presence of a possible collagen-binding domain.
1989
The insulin receptor and tyrosine protein kinase activity
1984
A novel integrin beta subunit is associated with the vitronectin receptor alpha subunit (alpha v) in a human osteosarcoma cell line and is a substrate for protein kinase C.
1989
Identification of the Hepatocyte Growth Factor Receptor As the c- met Proto-Oncogene Product
1991 StandoutScience
Reevaluation of the evidence that an antibody to the insulin receptor is insulinmimetic without activating the protein tyrosine kinase activity of the receptor.
1987
Characterization of the insulin receptor kinase purified from human placental membranes.
1983
Catalytic Asymmetric Synthesis of Unprotected β2-Amino Acids
2021 StandoutNobel
Protein Phosphatases: Properties and Role in Cellular Regulation
1983 Science
Identification of the Cystic Fibrosis Gene: Cloning and Characterization of Complementary DNA
1989 StandoutScience
A cascade of tyrosine autophosphorylation in the beta-subunit activates the phosphotransferase of the insulin receptor.
1988
cDNA for the human beta 2-adrenergic receptor: a protein with multiple membrane-spanning domains and encoded by a gene whose chromosomal location is shared with that of the receptor for platelet-derived growth factor.
1987 StandoutNobel
Microinjection of a protein-tyrosine-phosphatase inhibits insulin action in Xenopus oocytes.
1990 StandoutNobel
Cyclic AMP-dependent protein kinase closes the serotonin-sensitive K+channels of Aplysia sensory neurones in cell-free membrane patches
1985 StandoutNatureNobel
Purification of a Hepatic S6 Kinase from Cycloheximide-treated Rats
1989
Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells
1984 StandoutNature
Tyrosine phosphorylation of the insulin receptor beta subunit activates the receptor-associated tyrosine kinase activity.
1984
Okadaic acid mimics the action of insulin in stimulating protein kinase activity in isolated adipocytes. The role of protein phosphatase 2a in attenuation of the signal.
1990 StandoutNobel
daf-2 , an Insulin Receptor-Like Gene That Regulates Longevity and Diapause in Caenorhabditis elegans
1997 StandoutScienceNobel
The AGA1 Product Is Involved in Cell Surface Attachment of the Saccharomyces cerevisiae Cell Adhesion Glycoprotein a-Agglutinin
1991
Isolation and functional expression of a mammalian prohormone processing enzyme, murine prohormone convertase 1.
1991 StandoutNobel
p145, a Protein with Associated Tyrosine Kinase Activity in a Human Gastric Carcinoma Cell Line
1988
The role of antireceptor antibodies in stimulating phosphorylation of the insulin receptor.
1984
Human placenta protein-tyrosine-phosphatase: amino acid sequence and relationship to a family of receptor-like proteins.
1989 StandoutNobel
Insulin-Dependent Tyrosine Protein Kinase: Cellular Distribution and Copurification with the Insulin Receptor
1985
Increased phosphorylation of ribosomal protein S6 following microinjection of insulin receptor-kinase into Xenopus oocytes
1986 StandoutNatureNobel
Prohormone processing in Xenopus oocytes: characterization of cleavage signals and cleavage enzymes.
1991 StandoutNobel
Autophosphorylation of the PDGF receptor in the kinase insert region regulates interactions with cell proteins
1989
Structure and function of the leukocyte adhesion molecules CD11/CD18
1990
cDNA isolated from a human T-cell library encodes a member of the protein-tyrosine-phosphatase family.
1989 StandoutNobel
[11] Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates
1991
Insulin stimulated phosphorylation of its own receptor. Activation of a tyrosine-specific protein kinase that is tightly associated with the receptor.
1983
Insulin receptor is an insulin-dependent tyrosine protein kinase: copurification of insulin-binding activity and protein kinase activity to homogeneity from human placenta.
1984
Primary structure of the leukocyte function-associated molecule-1 alpha subunit: an integrin with an embedded domain defining a protein superfamily.
1989
Genomic structure of an integrin alpha subunit, the leukocyte p150,95 molecule.
1990
IRS-1-Mediated Inhibition of Insulin Receptor Tyrosine Kinase Activity in TNF-α- and Obesity-Induced Insulin Resistance
1996 StandoutScience
The role of protein phosphorylation in neural and hormonal control of cellular activity
1982 Nature
Kinetic properties of the insulin receptor tyrosine protein kinase: Activation through an insulin-stimulated tyrosine-specific, intramolecular autophosphorylation
1986
Potential positive and negative autoregulation of p60c-src by intermolecular autophosphorylation.
1988
Stimulation of protein phosphatase activity by insulin and growth factors in 3T3 cells.
1988 StandoutNobel
[62] 5′-p-fluorosulfonylbenzoyl adenosine as a probe of ATP-binding sites in hormone receptor-associated kinases
1985
Works of Mark Pierce being referenced
Adjunctive treatment of partial seizures with tiagabine: A placebo-controlled trial
1995
Cell-cell recognition in yeast. Characterization of the sexual agglutination factors from Saccharomyces kluyveri.
1983
Identification of insulin receptor tyrosine residues autophosphorylated in vitro.
1987
Identification of the insulin receptor tyrosine residues undergoing insulin-stimulated phosphorylation in intact rat hepatoma cells.
1988
Insulin-stimulated tyrosine phosphorylation of the insulin receptor in detergent extracts of human placental membranes. Comparison to epidermal growth factor-stimulated phosphorylation.
1982
ATP-citrate lyase. Structure of a tryptic peptide containing the phosphorylation site directed by glucagon and the cAMP-dependent protein kinase.
1981
Amino acid sequence of the alpha subunit of human leukocyte adhesion receptor Mo1 (complement receptor type 3).
1988
Leukocytes from four patients with complete or partial Leu-CAM deficiency contain the common beta-subunit precursor and beta-subunit messenger RNA.
1987
The insulin-directed phosphorylation site on ATP-citrate lyase is identical with the site phosphorylated by the cAMP-dependent protein kinase in vitro.
1982
Phosphorylation of human choriogonadotropin. Stoichiometry and sites of phosphate incorporation.
1983
Molecular cloning of the alpha subunit of human and guinea pig leukocyte adhesion glycoprotein Mo1: chromosomal localization and homology to the alpha subunits of integrins.
1988