Citation Impact
Citing Papers
Confirmation of intersubunit connectivity and topology of designed protein complexes by native MS
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Global analysis of protein folding using massively parallel design, synthesis, and testing
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Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1
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The 2‐His‐1‐Carboxylate Facial Triad — An Emerging Structural Motif in Mononuclear Non‐Heme Iron(II) Enzymes
1997
Crystallographic determination of the active site iron and its ligands in soybean lipoxygenase L-1
1993
C. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl Hydroxylation
2001 StandoutNobel
Circular Dichroism and X-ray Spectroscopies of Azotobacter vinelandii Nitrogenase Iron Protein
1996
Conserved histidine residues in soybean lipoxygenase: functional consequences of their replacement
1992
Homocitrate is a component of the iron-molybdenum cofactor of nitrogenase
1989
Intelligent design: the de novo engineering of proteins with specified functions
2006
A synthetic oscillatory network of transcriptional regulators
2000 StandoutNature
X‐ray absorption spectroscopy of soybean lipoxygenase‐1
1992
Perspectives on Non-Heme Iron Protein Chemistry
1991
Protein- and Metal-dependent Interactions of a Prominent Protein in Mussel Adhesive Plaques
2010
X-ray absorption spectroscopic studies of the high-spin iron(II) active site of isopenicillin N synthase: evidence for iron-sulfur interaction in the enzyme-substrate complex
1992
Structural analysis of heme proteins: implications for design and prediction
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New insights into structure-function relationships in nitrogenase: a 1.6 Å resolution X-ray crystallographic study of Klebsiella pneumoniae MoFe-protein
1999
The road to fully programmable protein catalysis
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Artificial Diiron Enzymes with a De Novo Designed Four‐Helix Bundle Structure
2015
Design and synthesis of multi-haem proteins
1994 Nature
De novo design of luciferases using deep learning
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Complexation‐Induced Translational Isomerism: Shuttling through Stepwise Competitive Binding
2005
Principles for designing ideal protein structures
2012 StandoutNatureNobel
Spectroscopic and Kinetic Properties of Unphosphorylated Rat Hepatic Phenylalanine Hydroxylase Expressed in Escherichia coli
1995
A new method for extraction of iron-molybdenum cofactor (FeMoco) from nitrogenase adsorbed to DEAE-cellulose. 2. Solubilization of FeMoco in a wide range of organic solvents
1989
Purification, composition, charge, and molecular weight of the FeMo cofactor from azotobacter vinelandii nitrogenase
1993
The diversity of the lipoxygenase family
1999
Thiolate ligation of the active site iron(II) of isopenicillin N synthase derives from substrate rather than endogenous cysteine: spectroscopic studies of site-specific Cys .fwdarw. Ser mutated enzymes
1992
Mössbauer spectroscopy applied to the oxidized and semi-reduced states of the iron-molybdenum cofactor of nitrogenase
1989
Absorption spectroscopy and binding constants for first-row transition metal complexes of a DOPA-containing peptide
2005
Catalytic C–H functionalization by metal carbenoid and nitrenoid insertion
2008 StandoutNature
Computational de novo Design, and Characterization of an A2B2 Diiron Protein
2002
Computational Design of an Unnatural Amino Acid Dependent Metalloprotein with Atomic Level Accuracy
2013 StandoutNobel
Mössbauer study of the native, reduced and substrate‐reacted Desulfovibrio gigas aldehyde oxido‐reductase
1992
The construction of metal centers in proteins by rational design
1998
Oxygenative cleavage of catechols including protocatechuic acid with molecular oxygen in water catalysed by water-soluble non-heme iron(iii) complexes in relevance to catechol dioxygenases
2002
Protein Complexes Are under Evolutionary Selection to Assemble via Ordered Pathways
2013
Overproduction, purification, and characterization of chlorocatechol dioxygenase, a non-heme iron dioxygenase with broad substrate tolerance
1991
De novo design of a fluorescence-activating β-barrel
2018 StandoutNatureNobel
Action of Soybean Lipoxygenase 1 on 12-Iodo-cis-9-octadecenoic Acid and 12-Bromo-cis-9-octadecenoic Acid
1995
Comparison of redox and EPR properties of the molybdenum iron proteins of Clostridium pasteurianum and Azotobacter vinelandii nitrogenases
1988
Q-band ENDOR spectra of the Rieske protein from Rhodobacter capsulatus ubiquinol-cytochrome c oxidoreductase show two histidines coordinated to the iron-sulfur [2Fe-2S] cluster
1991
HIF-1 Regulates Cytochrome Oxidase Subunits to Optimize Efficiency of Respiration in Hypoxic Cells
2007 StandoutNobel
Design of functional metalloproteins
2009 Nature
The cooperative binding of phenylalanine to phenylalanine 4‐monooxygenase studied by 1H‐NMR paramagnetic relaxation
1993
New insights from spectroscopy into the structure/function relationships of lipoxygenases
1997
Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation
2011 StandoutNatureNobel
Rational design of photosynthetic reaction center protein maquettes
2022
De novo proteins from designed combinatorial libraries
2004
Electron-nuclear double resonance spectroscopy of nitrogen-15-enriched phthalate dioxygenase from Pseudomonas cepacia proves that two histidines are coordinated to the [2Fe-2S] Rieske-type clusters
1989
[18] Resonance Raman spectroscopy of metalloproteins
1995
Resonance Raman Studies of Catecholate and Phenolate Complexes of Recombinant Human Tyrosine Hydroxylase
1995
[23] Protein structure and mechanism studied by electron nuclear double resonance spectroscopy
1995
The crystal structure of the designed trimeric coiled coil coil‐VaLd: Implications for engineering crystals and supramolecular assemblies
1997
The Formation of Straight and Twisted Filaments from Short Tau Peptides
2004
De novo design of a hyperstable non-natural protein–ligand complex with sub-Å accuracy
2017
Structural Effects of Crosslinking a Biopolymer Hydrogel Derived from Marine Mussel Adhesive Protein
2006
Why R-Homocitrate Is Essential to the Reactivity of FeMo-Cofactor of Nitrogenase: Studies on NifV--Extracted FeMo-Cofactor
1998 StandoutNobel
Experimental Evidence for Extensive Tunneling of Hydrogen in the Lipoxygenase Reaction: Implications for Enzyme Catalysis
1996
Electronic Structure and Reactivity of High-Spin Iron−Alkyl- and −Pterinperoxo Complexes
2002
Plausible structure of the iron-molybdenum cofactor of nitrogenase.
1992
A segment of cold shock protein directs the folding of a combinatorial protein
2005 StandoutNobel
De Novo Design and Structural Characterization of Proteins and Metalloproteins
1999
Reduction of Ferric Iron Could Drive Hydrogen Tunneling in Lipoxygenase Catalysis: Implications for Enzymatic and Chemical Mechanisms
1997
De NovoDesign of Helical Bundles as Models for Understanding Protein Folding and Function
2000
Geometric and Electronic Structure/Function Correlations in Non-Heme Iron Enzymes
1999 Standout
Dynamical Contributions to Enzyme Catalysis: Critical Tests of A Popular Hypothesis
2006 StandoutNobel
Random-coil behavior and the dimensions of chemically unfolded proteins
2004
Iron-Clad Fibers: A Metal-Based Biological Strategy for Hard Flexible Coatings
2010 Science
Structural, Spectroscopic, and Redox Consequences of a Central Ligand in the FeMoco of Nitrogenase: A Density Functional Theoretical Study
2003
Synthesis and Characterization of Novel Alkylperoxo Mononuclear Iron(III) Complexes with a Tripodal Pyridylamine Ligand: A Model for Peroxo Intermediates in Reactions Catalyzed by Non-Heme Iron Enzymes
1999
Cyanide and Methylisocyanide Binding to the Isolated Iron-Molybdenum Cofactor of Nitrogenase
1989
Nitrogenase from nifV mutants of Klebsiella pneumoniae contains an altered form of the iron-molybdenum cofactor
1984
Structure of soybean lipoxygenase L3 and a comparison with its L1 isoenzyme
1997
Three-Dimensional Structure of a Purple Lipoxygenase
2001
Oxygen Activation by Mononuclear Non‐Heme Iron Proteins
1996
pH-induced metal-ligand cross-links inspired by mussel yield self-healing polymer networks with near-covalent elastic moduli
2011 Standout
Dioxygen is the source of the mu-oxo bridge in iron ribonucleotide reductase.
1994
Dioxygen uptake and transfer by Co(III), Rh(III) and Ir(III) catecholate complexes
1992
Experimental Verification of a New Mechanism for Dissociative Chemisorption: Atom Abstraction
1995
Possible binding modes for dinitrogen activation by the FeMo-cofactor in nitrogenase
1997
Aminopyridine Iron Catecholate Complexes as Models for Intradiol Catechol Dioxygenases. Synthesis, Structure, Reactivity, and Spectroscopic Studies
2000
Structural Models for the Metal Centers in the Nitrogenase Molybdenum-Iron Protein
1992 Science
Photoswitchable Intramolecular H-Stacking of Perylenebisimide
2010 StandoutNobel
De Novo Design of Four-Helix Bundle Metalloproteins: One Scaffold, Diverse Reactivities
2019
Tetrahydropterin-Dependent Amino Acid Hydroxylases
1999
Temperature-Dependent Isotope Effects in Soybean Lipoxygenase-1: Correlating Hydrogen Tunneling with Protein Dynamics
2002
Isolation by crystallization of translational isomers of a bistable donor-acceptor [2]catenane
2010 StandoutNobel
Density Functional Theory Calculations and Exploration of a Possible Mechanism of N2 Reduction by Nitrogenase
2004
Structural and Functional Aspects of Metal Sites in Biology
1996 Standout
Functionally Rigid Bistable [2]Rotaxanes
2007 StandoutNobel
Stiff Coatings on Compliant Biofibers: The Cuticle of Mytilus californianus Byssal Threads,
2009
Synthesis, Structural Characterization, and Extradiol Oxygenation of Iron−Catecholato Complexes with Hydrotris(pyrazolyl)borate Ligands,
1998
Strong Radical Character of the Catecholate Ligand of Catecholato(pyridine)iron Complexes Involved in the Catecholdioxygenase-model Reaction
1991
Effects of oxidation state, solvent acidity and thiophenol on the electrochemical properties of iron-molybdenum cofactor from nitrogenase
1990
Regulation of rat liver phenylalanine hydroxylase. I. Kinetic properties of the enzyme's iron and enzyme reduction site.
1994
Oxygen Sensing and the Transcriptional Regulation of Oxygen-Responsive Genes in Yeast
1998
Activation of chelated catecholatoiron species for catalytic oxygenation of catechols by catecholdioxygenase-model iron complexes
1994
Synthetic Models for the Cysteinate-Ligated Non-Heme Iron Enzyme Superoxide Reductase: Observation and Structural Characterization by XAS of an FeIII−OOH Intermediate
2002
Detailed Spectroscopic and Theoretical Studies on [Fe(EDTA)(O2)]3-: Electronic Structure of the Side-on Ferric−Peroxide Bond and Its Relevance to Reactivity
1998
Resonance Raman studies on the blue-green-colored bovine adrenal tyrosine 3-monooxygenase (tyrosine hydroxylase). Evidence that the feedback inhibitors adrenaline and noradrenaline are coordinated to iron.
1988
Mössbauer, EPR, and magnetization studies of the Azotobacter vinelandii Fe protein. Evidence for a [4Fe-4S]1+ cluster with spin S = 3/2.
1985
Structural and Spectroscopic Features of a cis (Hydroxo)-FeIII-(Carboxylato) Configuration as an Active Site Model for Lipoxygenases
2002
De novo design of protein homo-oligomers with modular hydrogen-bond network–mediated specificity
2016 StandoutScienceNobel
Mechanism of Molybdenum Nitrogenase
1996 Standout
Nitrogen Binding to the FeMo-Cofactor of Nitrogenase
2003
Pterin-Dependent Amino Acid Hydroxylases
1996
Solubilization of the iron molybdenum cofactor of Azotobacter vinelandii nitrogenase in dimethylformamide and acetonitrile
1986
Quantum Chemical Approach to the Assignment of Iron−Catecholate Vibrations and Isotopic Substitution Shifts
1996
High thermodynamic stability of parametrically designed helical bundles
2014 StandoutScienceNobel
The Clusters of Nitrogenase: Synthetic Methodology in the Construction of Weak-Field Clusters
2003
Mössbauer studies of solid thionin-oxidized MoFe protein of nitrogenase.
1988
Identification by ENDOR of Trp 191 as the Free-Radical Site in Cytochrome c Peroxidase Compound ES
1989 Science
Catalytic Reaction Mechanism of Lipoxygenase. A Density Functional Theory Study
2003
Protein Design: A Hierarchic Approach
1995 Science
Simulations of the Large Kinetic Isotope Effect and the Temperature Dependence of the Hydrogen Atom Transfer in Lipoxygenase
2004 StandoutNobel
Long-range order in the src SH3 folding transition state
2000 StandoutNobel
Dioxygen Activation at Mononuclear Nonheme Iron Active Sites: Enzymes, Models, and Intermediates
2004 Standout
Synthesis and Gelation of DOPA-Modified Poly(ethylene glycol) Hydrogels
2002
Engineering of the iron site in ribonucleotide reductase to a self-hydroxylating monooxygenase.
1992
De novo design of covalently constrained mesosize protein scaffolds with unique tertiary structures
2017 StandoutNobel
Complexation‐Induced Translational Isomerism: Shuttling through Stepwise Competitive Binding
2005
Crystallographic Structure of the Nitrogenase Iron Protein from Azotobacter vinelandii
1992 Science
Hydrogen-Bonding Cavities about Metal Ions: Synthesis, Structure, and Physical Properties for a Series of Monomeric M−OH Complexes Derived from Water
2001
Extradiol oxygenation of 3,5-di-tert-butylcatechol with O2by iron chlorides in tetrahydrofuran–water as a model reaction for catechol-2,3-dioxygenases
1994
Coordinatively Unsaturated Metal Centers in the Extended Porous Framework of Zn3(BDC)3·6CH3OH (BDC = 1,4-Benzenedicarboxylate)
1998 StandoutNobel
Spectroscopic and Functional Characterization of a Ligand Coordination Mutant of Soybean Lipoxygenase-1: First Coordination Sphere Analogue of Human 15-Lipoxygenase
1998
A polyoxoanion-based iron(II) catechol extradiol dioxygenase: oxygenation of 3,5-di-tert-butylcatechol by the polyoxoanion-supported iron(II) complex (n-Bu4N)7[(CH3CN) FeII·P2W15Nb3O62]
1999
Existence of a “Hot” Atom Mechanism for the Dissociation ofO 2
1996 StandoutNobel
C−H Bond Activation by a Ferric Methoxide Complex: A Model for the Rate-Determining Step in the Mechanism of Lipoxygenase
1997
Interconversion of two oxidized forms of taurine/α-ketoglutarate dioxygenase, a non-heme iron hydroxylase: Evidence for bicarbonate binding
2003
De Novo Design of Native Proteins: Characterization of Proteins Intended To Fold into Antiparallel, Rop-like, Four-Helix Bundles
1997
Elicitation of thiomolybdates from the iron‐molybdenum cofactor of nitrogenase
1986
Cluster analysis and display of genome-wide expression patterns
1998 Standout
Isolated iron-molybdenum cofactor of nitrogenase exists in multiple forms in its oxidized and semi-reduced states
1989
Molybdenum Triamidoamine Complexes that Contain Hexa-tert-butylterphenyl, Hexamethylterphenyl, or p-Bromohexaisopropylterphenyl Substituents. An Examination of Some Catalyst Variations for the Catalytic Reduction of Dinitrogen
2004 StandoutNobel
Protein Control of Redox Potentials of Iron−Sulfur Proteins
1996 StandoutNobel
Crystal Structure of the Biphenyl-Cleaving Extradiol Dioxygenase from a PCB-Degrading Pseudomonad
1995 Science
Ferredoxin and ferredoxin–heme maquettes
1996
Protein Design: Toward Functional Metalloenzymes
2014
Activation of C−H Bonds by Metal Complexes
1997 Standout
Electrostatic Basis for Enzyme Catalysis
2006 StandoutNobel
Functional Models for Catechol 1,2-Dioxygenase. Synthesis, Structure, Spectra, and Catalytic Activity of Certain Tripodal Iron(III) Complexes
1998
Heme Protein Assemblies
2004
Chemomimetic Biocatalysis: Exploiting the Synthetic Potential of Cofactor-Dependent Enzymes To Create New Catalysts
2015 StandoutNobel
Model Studies of Catechol Dioxygenases. Important Role of Monodentate Catecholate-Iron(III) Intermediate
1993
Role of the nonheme Fe(II) center in the biosynthesis of the plant hormone ethylene
1999
Bioinspired Metal–Organic Framework Catalysts for Selective Methane Oxidation to Methanol
2018 StandoutNobel
Catalytic Reduction of Dinitrogen to Ammonia at a Single Molybdenum Center
2003 StandoutScienceNobel
Improving the Catalytic Performance of an Artificial Metalloenzyme by Computational Design
2015 StandoutNobel
Synthesis, X-ray Structural Determination, and Magnetic Susceptibility, Mössbauer, and EPR Studies of (Ph4P)2[Fe2(Cat)4(H2O)2]·6H2O, a Catecholato-Bridged Dimer of Iron(III)
1996
C−H Bond Activation by a Ferric Methoxide Complex: Modeling the Rate-Determining Step in the Mechanism of Lipoxygenase
2001
Theoretical Studies of Biological Nitrogen Fixation. I. Density Functional Modeling of the Mo-Site of the FeMo-Cofactor
2001
Ring-opening dioxygenatton of 3,5-Di-t-butylcatechol by FeCl2/monodentate ligand/bidentate ligand systems
1990
A Theoretical Model for the Active Site of Nitrogenase
1996
Structure and electronic properties of (N,N′-bis(4-methyl-6-tert-butyl-2-methyl-phenolato)-N,N′-bismethyl-1,2-diaminoethaneFeIII (DBSQ). Spectroelectrochemical study of the red-ox properties. Relevance to intradiol catechol dioxygenases
1997
De novo design of protein homodimers containing tunable symmetric protein pockets
2022 StandoutNobel
Electron Paramagnetic Resonance Spectroscopy of the Iron−Molybdenum Cofactor of Clostridium pasteurianum Nitrogenase
1996
Raman Evidence for a Weakened O−O Bond in Mononuclear Low-Spin Iron(III)−Hydroperoxides
1998 StandoutNobel
Mechanistic Studies on Synthetic Fe−S-Based Clusters and Their Relevance to the Action of Nitrogenases
2005 StandoutNobel
Design of Novel Inorganic−Organic Hybrid Materials Based on Iron-Chloranilate Mononuclear Complexes: Characteristics of Hydrogen-Bond-Supported Layers toward the Intercalation of Guests
2002 StandoutNobel
Femtosecond X-Ray Fluorescence
2000 StandoutNobel
A Multiplet Analysis of Fe K-Edge 1s → 3d Pre-Edge Features of Iron Complexes
1997
The Three-Dimensional Structure of an Arachidonic Acid 15-Lipoxygenase
1993 Science
Design of Heme Enzymes with a Tunable Substrate Binding Pocket Adjacent to an Open Metal Coordination Site
2023 StandoutNobel
Strong reversible Fe 3+ -mediated bridging between dopa-containing protein films in water
2010
Transition state heterogeneity in GCN4 coiled coil folding studied by using multisite mutations and crosslinking
1999
Magnetic circular dichroism spectroscopy as a probe of the geometric and electronic structure of non-heme ferrous enzymes
1995
Prediction of Nucleating Sequences from Amyloidogenic Propensities of Tau-Related Peptides
2006
Simultaneous binding of nitric oxide and isotopically labeled substrates or inhibitors by reduced protocatechuate 3,4-dioxygenase.
1993
Effect of Carboxamido N Coordination to Iron on the Redox Potential of Low-Spin Non-Heme Iron Centers with N,S Coordination: Relevance to the Iron Site of Nitrile Hydratase
1998
Proton-Coupled Electron Transfer in Soybean Lipoxygenase
2004
A highly reactive functional model for catechol 1,2-dioxygenase: reactivity studies of iron(iii) catecholate complexes of bis[(2-pyridyl)methyl][(1-methylimidazol-2-yl)methyl]amine
1997
Dioxygen Activation by Enzymes with Mononuclear Non-Heme Iron Active Sites
1996
Structural Adaptability Facilitates Histidine Heme Ligation in a Cytochrome P450
2015 StandoutNobel
Works of Mark Nelson being referenced
X-ray Spectroscopy of the Iron Site in Soybean Lipoxygenase-1: Changes in Coordination upon Oxidation or Addition of Methanol
1994
Enzyme-bound pentadienyl and peroxyl radicals in purple lipoxygenase
1990
Structural Characterization of Alkyl and Peroxyl Radicals in Solutions of Purple Lipoxygenase
1994
The structure and function of lipoxygenase
1994
Catecholate LMCT bands as probes for the active sites of nonheme iron oxygenases
1988
A Stereoselective Cobalt-Containing Nitrile Hydratase
1997
The nitric oxide complex of ferrous soybean lipoxygenase-1. Substrate, pH, and ethanol effects on the active-site iron.
1987
Metal and sulfur composition of iron-molybdenum cofactor of nitrogenase.
1983
Iron-57 hyperfine coupling tensors of the FeMo cluster in Azotobacter vinelandii MoFe protein: determination by polycrystalline ENDOR spectroscopy
1988
Coordination sphere of the ferric ion in nitrile hydratase
1993
ENDOR of the resting state of nitrogenase molybdenum-iron proteins from Azotobacter vinelandii, Klebsiella pneumoniae, and Clostridium pasteurianum. Proton, iron-57, molybdenum-95, and sulfur-33 studies
1986
X-ray Spectroscopy of Nitrile Hydratase at pH 7 and 9
1996
Nitrile Hydratase from Rhodococcus rhodochrous J1 Contains a Non-Corrin Cobalt Ion with Two Sulfur Ligands
1996
X-ray Spectroscopy of Nitric Oxide Binding to Iron in Inactive Nitrile Hydratase and a Synthetic Model Compound
1998
The adsorption and reaction of fluorine on the Si(100) surface
1989
Kinetics of the adsorption of O2 and of the desorption of SiO on Si(100): A molecular beam, XPS, and ISS study
1987
A novel iron-sulfur center in nitrile hydratase from Brevibacterium sp
1991
Iron EXAFS of the iron-molybdenum cofactor of nitrogenase
1982
Resonance Raman Spectroscopy of Nitrile Hydratase, a Novel Iron−Sulfur Enzyme
1996
Catecholate complexes of ferric soybean lipoxygenase 1
1988
Reduction of the active-site iron by potent inhibitors of lipoxygenases
1991
Ferric Ion Complexes of a DOPA-Containing Adhesive Protein from Mytilus edulis
1996
Design of a heme-binding four-helix bundle
1994