Citation Impact
Citing Papers
Temporal calcium profiling of specific circadian neurons in freely moving flies
2017 StandoutNobel
Sec1p directly stimulates SNARE-mediated membrane fusion in vitro
2004
Ultrahigh-resolution imaging reveals formation of neuronal SNARE/Munc18 complexes in situ
2013 StandoutNobel
SNARE Proteins: One to Fuse and Three to Keep the Nascent Fusion Pore Open
2012 StandoutScienceNobel
SNARE Function Analyzed in Synaptobrevin/VAMP Knockout Mice
2001 StandoutScienceNobel
Conformational Switch of Syntaxin-1 Controls Synaptic Vesicle Fusion
2008 StandoutScienceNobel
Fusion of Cells by Flipped SNAREs
2003 StandoutScienceNobel
Syntaxin N-terminal peptide motif is an initiation factor for the assembly of the SNARE–Sec1/Munc18 membrane fusion complex
2010
Munc18-1 binds directly to the neuronal SNARE complex
2007 StandoutNobel
Convergence and divergence in the mechanism of SNARE binding by Sec1/Munc18-like proteins
2002 StandoutNobel
Plug-and-Play Genetic Access to Drosophila Cell Types using Exchangeable Exon Cassettes
2015
Notch Signaling Modulates Sleep Homeostasis and Learning after Sleep Deprivation in Drosophila
2011
Munc18-2, a Functional Partner of Syntaxin 3, Controls Apical Membrane Trafficking in Epithelial Cells
2000
Munc18-1 Tuning of Vesicle Merger and Fusion Pore Properties
2011 StandoutNobel
Sec1/Munc18 Proteins
2000
The riddle of the Sec1/Munc-18 proteins – new twists added to their interactions with SNAREs
2003
Sleep, aging, and lifespan in Drosophila
2010
The X-ray crystal structure of neuronal Sec1 from squid sheds new light on the role of this protein in exocytosis
2000
The molecular machinery of synaptic vesicle exocytosis
2003
Regulation of Circadian Behavioral Output via a MicroRNA-JAK/STAT Circuit
2012
SNAREs and SNARE regulators in membrane fusion and exocytosis
1999
Vesicle trafficking: pleasure and pain from SM genes
2003
The presynaptic cytomatrix of brain synapses
2001
Membrane Tethering and Fusion in the Secretory and Endocytic Pathways
2000
High-Resolution Positional Tracking for Long-Term Analysis of Drosophila Sleep and Locomotion Using the “Tracker” Program
2012
Functional and physical coupling of voltage‐sensitive calcium channels with exocytotic proteins: ramifications for the secretion mechanism
2001
Accessory factors in clathrin-dependent synaptic vesicle endocytosis
2000
Multiple Cargo Binding Sites on the COPII Subunit Sec24p Ensure Capture of Diverse Membrane Proteins into Transport Vesicles
2003 StandoutNobel
Drosophila CAPS Is an Essential Gene that Regulates Dense-Core Vesicle Release and Synaptic Vesicle Fusion
2001
Snares and munc18 in synaptic vesicle fusion
2002 StandoutNobel
Membrane Trafficking: Three Steps to Fusion
2007
Protein Repeats: Structures, Functions, and Evolution
2001
Modulation of the Frequency Response ofShakerPotassium Channels by the Quiver Peptide Suggesting a Novel Extracellular Interaction Mechanism
2010
Regulated portals of entry into the cell
2003 StandoutNature
C. elegans Notch Signaling Regulates Adult Chemosensory Response and Larval Molting Quiescence
2011
A transcriptional reporter of intracellular Ca2+ in Drosophila
2015
Dual PDF Signaling Pathways Reset Clocks Via TIMELESS and Acutely Excite Target Neurons to Control Circadian Behavior
2014
α-Neurexins are required for efficient transmitter release and synaptic homeostasis at the mouse neuromuscular junction
2006
Titration of Syntaxin1 in Mammalian Synapses Reveals Multiple Roles in Vesicle Docking, Priming, and Release Probability
2013 StandoutNobel
Rational design of α-helical tandem repeat proteins with closed architectures
2015 StandoutNatureNobel
Astrocyte-Derived Adenosine and A1Receptor Activity Contribute to Sleep Loss-Induced Deficits in Hippocampal Synaptic Plasticity and Memory in Mice
2011
Synthetic Par polarity induces cytoskeleton asymmetry in unpolarized mammalian cells
2023 StandoutNobel
Membrane Fusion
2003 StandoutNobel
α-Synuclein Cooperates with CSPα in Preventing Neurodegeneration
2005 StandoutNobel
Short Neuropeptide F Is a Sleep-Promoting Inhibitory Modulator
2013 StandoutNobel
Defects in synaptic vesicle docking in unc-18 mutants
2003
Drosophila CLOCK target gene characterization: implications for circadian tissue-specific gene expression
2011 StandoutNobel
Recognizing Phosphatidylinositol 3-Phosphate
2001
Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells
2000
Sar1p N-Terminal Helix Initiates Membrane Curvature and Completes the Fission of a COPII Vesicle
2005 StandoutNobel
Crystal structures of neuronal squid Sec1 implicate inter-domain hinge movement in the release of t-SNAREs11Edited by R. Huber
2001
Three-dimensional structure of the neuronal-Sec1–syntaxin 1a complex
2000 Nature
Crystal Structure of the Atypical Protein Kinase Domain of a TRP Channel with Phosphotransferase Activity
2001
The impact of sleep deprivation on neuronal and glial signaling pathways important for memory and synaptic plasticity
2012
A dual function for Munc‐18 in exocytosis of PC12 cells
2005
A dual-Ca2+-sensor model for neurotransmitter release in a central synapse
2007 StandoutNatureNobel
Adaptor-related proteins
2001
Genetics of Sleep and Sleep Disorders
2011
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
Directional Notch trafficking in Sara endosomes during asymmetric cell division in the spinal cord
2015
Sly1 Binds to Golgi and ER Syntaxins via a Conserved N-Terminal Peptide Motif
2002 StandoutNobel
Class C Vps Protein Complex Regulates Vacuolar SNARE Pairing and Is Required for Vesicle Docking/Fusion
2000
Systematic analysis of genes required for synapse structure and function
2005 StandoutNatureNobel
The See1p homologue Vps45p binds to the syntaxin Tlg2p
1998
The ESCRT Pathway
2011
Structural basis for recognition of acidic-cluster dileucine sequence by GGA1
2002 Nature
DrosophilaQVR/SSS Modulates the Activation and C-Type Inactivation Kinetics of Shaker K+Channels
2011
A Molecular Basis for Interactions Between Sleep and Memory
2011
Syntaxin 1A Interacts with Multiple Exocytic Proteins to Regulate Neurotransmitter Release In Vivo
1999
Cysteine‐String Protein
2000
Munc18-dependent regulation of synaptic vesicle exocytosis by syntaxin-1A in hippocampal neurons
2005
The genetic and molecular regulation of sleep: from fruit flies to humans
2009
Selective Activation of Cognate SNAREpins by Sec1/Munc18 Proteins
2007 StandoutNobel
Structural basis for acidic-cluster-dileucine sorting-signal recognition by VHS domains
2002 Nature
α-Neurexins couple Ca2+ channels to synaptic vesicle exocytosis
2003 StandoutNatureNobel
CLOCK deubiquitylation by USP8 inhibits CLK/CYC transcription in Drosophila
2012 StandoutNobel
Munc-18-1 Regulates the Initial Release Rate of Exocytosis
2007
Circadian Organization of Behavior and Physiology in Drosophila
2010
Munc18a Scaffolds SNARE Assembly to Promote Membrane Fusion
2008
Synthesis and Function of 3-Phosphorylated Inositol Lipids
2001 Standout
Role of Drosophila Rab5 during endosomal trafficking at the synapse and evoked neurotransmitter release
2003
The yeasts Rho1p and Pkc1p regulate the transport of chitin synthase III (Chs3p) from internal stores to the plasma membrane
2003 StandoutNobel
SNARE bundle and syntaxin N-peptide constitute a minimal complement for Munc18-1 activation of membrane fusion
2010 StandoutNobel
Binding of UNC-18 to the N-terminus of syntaxin is essential for neurotransmission in Caenorhabditis elegans
2008
Specific SNARE complex binding mode of the Sec1/Munc-18 protein, Sec1p
2006
Imaging single membrane fusion events mediated by SNARE proteins
2004 StandoutNobel
The Protein Kinase Complement of the Human Genome
2002 StandoutScience
Ordering the Final Events in Yeast Exocytosis
2000
Nsec1 Binds a Closed Conformation of Syntaxin1a
2000
Mechanisms of Synaptic Vesicle Exocytosis
2000
SNAREpin/Munc18 promotes adhesion and fusion of large vesicles to giant membranes
2008 StandoutNobel
Comparison of Cysteine String Protein (Csp) and Mutant α-SNAP Overexpression Reveals a Role for Csp in Late Steps of Membrane Fusion in Dense-Core Granule Exocytosis in Adrenal Chromaffin Cells
2000
Sec1p Binds to SNARE Complexes and Concentrates at Sites of Secretion
1999
Munc18-1 binding to the neuronal SNARE complex controls synaptic vesicle priming
2009 StandoutNobel
Control of Sleep and Wakefulness
2012
mir-276a strengthens Drosophila circadian rhythms by regulating timeless expression
2016 StandoutNobel
Phosphoinositides in membrane traffic at the synapse
2001
Overexpression of Cysteine-String Proteins inDrosophilaReveals Interactions with Syntaxin
1999
NSF Function in Neurotransmitter Release Involves Rearrangement of the SNARE Complex Downstream of Synaptic Vesicle Docking
1998
ADAPTORS FOR CLATHRIN COATS: Structure and Function
2004
The mammalian central nervous synaptic cleft contains a high density of periodically organized complexes
2005 StandoutNobel
Control of Fusion Pore Dynamics During Exocytosis by Munc18
2001 Science
About Sleep's Role in Memory
2013 Standout
Bruchpilot Promotes Active Zone Assembly, Ca 2+ Channel Clustering, and Vesicle Release
2006 StandoutScienceNobel
Endosomal sorting of readily releasable synaptic vesicles
2010 StandoutNobel
Proenkephalin+regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function
2020 StandoutNobel
Geranylgeranylated Snares Are Dominant Inhibitors of Membrane Fusion
2000 StandoutNobel
CSPα-deficiency causes massive and rapid photoreceptor degeneration
2006 StandoutNobel
Amyloid precursor protein (APP) traffics from the cell surface via endosomes for amyloid β (Aβ) production in the trans -Golgi network
2012 StandoutNobel
Membrane Fusion: Grappling with SNARE and SM Proteins
2009 StandoutScienceNobel
Nascent-Seq analysis of Drosophila cycling gene expression
2013 StandoutNobel
Decoding the Interactions of SM Proteins with SNAREs
2005
Secretory Granule Exocytosis
2003
The WD40 and FYVE domain containing protein 2 defines a class of early endosomes necessary for endocytosis
2006 StandoutNobel
UNC-18 Promotes Both the Anterograde Trafficking and Synaptic Function of Syntaxin
2008
Delayed Release of Neurotransmitter from Cerebellar Granule Cells
1998
Circadian neuron feedback controls the Drosophila sleep–activity profile
2016 StandoutNatureNobel
Mouse neurexin-1α deletion causes correlated electrophysiological and behavioral changes consistent with cognitive impairments
2009 StandoutNobel
Munc18-1 Regulates Early and Late Stages of Exocytosis via Syntaxin-independent Protein Interactions
2004
Works of Mark N. Wu being referenced
An Isoform-Specific Mutant Reveals a Role of PDP1ε in the Circadian Oscillator
2009
ROP, the Drosophila Sec1 homolog, interacts with syntaxin and regulates neurotransmitter release in a dosage-dependent manner
1998
A Genetic Screen for Sleep and Circadian Mutants Reveals Mechanisms Underlying Regulation of Sleep in Drosophila
2008
SLEEPLESS, a Ly-6/neurotoxin family member, regulates the levels, localization and activity of Shaker
2009
Improved and expanded Q-system reagents for genetic manipulations
2015
Two Dopaminergic Neurons Signal to the Dorsal Fan-Shaped Body to Promote Wakefulness in Drosophila
2012
Crystal Structure of the VHS and FYVE Tandem Domains of Hrs, a Protein Involved in Membrane Trafficking and Signal Transduction
2000
The Effects of Caffeine on Sleep inDrosophilaRequire PKA Activity, But Not the Adenosine Receptor
2009
Genetic dissection of synaptic transmission in Drosophila
1997
Genome-Wide Association Studies of Sleep Disorders
2011
Identification of SLEEPLESS, a Sleep-Promoting Factor
2008 Science