Standout Papers
Citation Impact
Citing Papers
Protein characterization of Saccharomyces cerevisiae RNA polymerase II after in vivo cross-linking
2007 StandoutNobel
Myd88-dependent positioning of Ptgs2-expressing stromal cells maintains colonic epithelial proliferation during injury
2007
Mitogenic Influence of Human R-Spondin1 on the Intestinal Epithelium
2005 Science
In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter
2010 StandoutNobel
Activated macrophages are an adaptive element of the colonic epithelial progenitor niche necessary for regenerative responses to injury
2004
Wnt/β-catenin signaling is required for CNS, but not non-CNS, angiogenesis
2009
Strategy for Dual-Analyte Luciferin Imaging: In Vivo Bioluminescence Detection of Hydrogen Peroxide and Caspase Activity in a Murine Model of Acute Inflammation
2013 StandoutNobel
Application of bio-orthogonal proteome labeling to cell transplantation and heterochronic parabiosis
2017
Rapid Loss of Intestinal Crypts upon Conditional Deletion of the Wnt/Tcf-4 Target Gene c-Myc
2006
Functional intestinal stem cells after Paneth cell ablation induced by the loss of transcription factor Math1 (Atoh1)
2012
Sustained in vitro intestinal epithelial culture within a Wnt-dependent stem cell niche
2009 Nobel
Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m 6 A-demethylation of NANOG mRNA
2016 StandoutNobel
Release of Ca2+ from a nonmitochondrial intracellular store in pancreatic acinar cells by inositol-1,4,5-trisphosphate
1983 StandoutNature
Progenitors of skeletal muscle satellite cells express the muscle determination gene, MyoD
2009
Aging, Rejuvenation, and Epigenetic Reprogramming: Resetting the Aging Clock
2012
Proteins regulating Ras and its relatives
1993 StandoutNature
RIM Proteins Tether Ca2+ Channels to Presynaptic Active Zones via a Direct PDZ-Domain Interaction
2011 StandoutNobel
Pericytes are required for blood–brain barrier integrity during embryogenesis
2010 StandoutNature
Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice
2014
Adult satellite cells and embryonic muscle progenitors have distinct genetic requirements
2009 Nature
Rejuvenation of Regeneration in the Aging Central Nervous System
2012
Epigenetic regulation of aging stem cells
2011
Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts
2010 StandoutNature
The genetics of ageing
2010 StandoutNature
Hsp90 as a capacitor for morphological evolution
1998 StandoutNature
HMGB1/RAGE regulates muscle satellite cell homeostasis via p38 MAPK/myogenin-dependent repression of Pax7 transcription
2012
WNT and β-catenin signalling: diseases and therapies
2004 Standout
Mammalian Ras interacts directly with the serine/threonine kinase raf
1993 Standout
Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium
2011 Standout
Intestinal lineage commitment of embryonic stem cells
2010
The aged niche disrupts muscle stem cell quiescence
2012 Nature
Genome-Wide Occupancy Profile of Mediator and the Srb8-11 Module Reveals Interactions with Coding Regions
2006
Poor Repair of Skeletal Muscle in Aging Mice Reflects a Defect in Local, Interleukin-33-Dependent Accumulation of Regulatory T Cells
2016
Reprogramming aging and progeria
2012
Wnt signaling in the intestinal epithelium: from endoderm to cancer
2005
NF-κB inhibition delays DNA damage–induced senescence and aging in mice
2012
The Intestinal Wnt/TCF Signature
2006
The bone marrow niche for haematopoietic stem cells
2014 StandoutNature
Phosphatidylinositol-3-OH kinase direct target of Ras
1994 StandoutNature
Recombinant adenovirus as a methodology for exploration of physiologic functions of growth factor pathways
2007
A Temporal Switch from Notch to Wnt Signaling in Muscle Stem Cells Is Necessary for Normal Adult Myogenesis
2008
Heterochronic parabiosis for the study of the effects of aging on stem cells and their niches
2012
Molecular chaperones in protein folding and proteostasis
2011 StandoutNature
Improved Cutaneous Healing in Diabetic Mice Exposed to Healthy Peripheral Circulation
2009
Transcription Factor Achaete Scute-Like 2 Controls Intestinal Stem Cell Fate
2009
Enterochromaffin Cells Are Gut Chemosensors that Couple to Sensory Neural Pathways
2017 StandoutNobel
Small molecule–mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer
2009
Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling
2011 Nature
Integrating Physiological Regulation with Stem Cell and Tissue Homeostasis
2011
Growth Differentiation Factor 11 Is a Circulating Factor that Reverses Age-Related Cardiac Hypertrophy
2013 Standout
Stems Cells and the Pathways to Aging and Cancer
2008
The intestinal stem cell
2008
Inducible cre-mediated control of gene expression in the murine gastrointestinal tract: effect of loss of β-catenin
2004
Paracrine and Autocrine Signals Induce and Maintain Mesenchymal and Stem Cell States in the Breast
2011
Emerging models and paradigms for stem cell ageing
2011
Age-associated inflammation inhibits epidermal stem cell function
2012
Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids
2018 StandoutNobel
Sprouty1 Regulates Reversible Quiescence of a Self-Renewing Adult Muscle Stem Cell Pool during Regeneration
2010
Expression Pattern of Wnt Signaling Components in the Adult Intestine
2005
Origin and physiological roles of inflammation
2008 StandoutNature
The Human Microbiome Project
2007 StandoutNature
Muscle-derived stem/progenitor cell dysfunction limits healthspan and lifespan in a murine progeria model
2012
Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling
2017 StandoutNatureNobel
Apc Tumor Suppressor Gene Is the “Zonation-Keeper” of Mouse Liver
2006
Mutations Modulating Raf Signaling in Drosophila Eye Development
1996
The role of senescent cells in ageing
2014 StandoutNature
Muscle injury activates resident fibro/adipogenic progenitors that facilitate myogenesis
2010
Syndecan-4-Expressing Muscle Progenitor Cells in the SP Engraft as Satellite Cells during Muscle Regeneration
2009
Gastrointestinal Stem Cells. II. Intestinal stem cells
2005
The depletion of skeletal muscle satellite cells with age is concomitant with reduced capacity of single progenitors to produce reserve progeny
2010
An FGF receptor signaling pathway is required for the normal cell migrations of the sex myoblasts in C. elegans hermaphrodites
1995 StandoutNobel
Cerebral organoids model human brain development and microcephaly
2013 StandoutNature
The Hallmarks of Aging
2013 Standout
The deubiquitination enzyme Fat facets negatively regulates RTK/Ras/MAPK signalling during Drosophila eye development
1997
Macrophage biology in development, homeostasis and disease
2013 StandoutNature
Delayed and Accelerated Aging Share Common Longevity Assurance Mechanisms
2008
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
2016 StandoutNature
Pericytes regulate the blood–brain barrier
2010 StandoutNature
Wnt signalling in stem cells and cancer
2005 StandoutNature
Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
2009 StandoutNature
Crypt stem cells as the cells-of-origin of intestinal cancer
2008 StandoutNature
An elt-3/elt-5/elt-6 GATA Transcription Circuit Guides Aging in C. elegans
2008
Identification of stem cells in small intestine and colon by marker gene Lgr5
2007 StandoutNature
Receptor subtype discrimination using extensive shape complementary designed interfaces
2019 StandoutNobel
Synergistic effect of A23187 and a phorbol ester on amylase secretion from rabbit pancreatic acini
1984
Discrete changes of cell membrane capacitance observed under conditions of enhanced secretion in bovine adrenal chromaffin cells.
1982 StandoutNobel
β-Arrestin2 mediates the initiation and progression of myeloid leukemia
2012 StandoutNobel
Tissue Tregs
2016
Stroma provides an intestinal stem cell niche in the absence of epithelial Wnts
2014
Aging, Cellular Senescence, and Cancer
2012 Standout
Activation of Wnt signalling in acute myeloid leukemia by induction of Frizzled-4
1992
Calcium uptake into acini from rat pancreas: Evidence for intracellular ATP-dependent calcium sequestration
1982
Skeletal Muscle Satellite Cells Are Committed to Myogenesis and Do Not Spontaneously Adopt Nonmyogenic Fates
2011
Interactions Between the Microbiota and the Immune System
2012 StandoutScience
Sox9 regulates cell proliferation and is required for Paneth cell differentiation in the intestinal epithelium
2007
Organogenesis in a dish: Modeling development and disease using organoid technologies
2014 StandoutScience
Control of cell fate determination by p21ras/Ras1, an essential component of torso signaling in Drosophila.
1993
R-Spondin1 regulates Wnt signaling by inhibiting internalization of LRP6
2007
Binding of Neuroligins to PSD-95
1997 StandoutScienceNobel
Elucidation of the role of breathless, a Drosophila FGF receptor homolog, in tracheal cell migration.
1994
Studies and Perspectives of Protein Kinase C
1986 StandoutScience
SYNTHESIS, INTRACELLULAR TRANSPORT AND DISCHARGE OF EXPORTABLE PROTEINS IN THE PANCREATIC ACINAR CELL AND OTHER CELLS
1978
THE WNT SIGNALING PATHWAY IN DEVELOPMENT AND DISEASE
2004 Standout
Proenkephalin+regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function
2020 StandoutNobel
Augmented Wnt Signaling in a Mammalian Model of Accelerated Aging
2007 Science
Canonical Wnt signalling induces satellite-cell proliferation during adult skeletal muscle regeneration
2008
A Localized Wnt Signal Orients Asymmetric Stem Cell Division in Vitro
2013 StandoutScienceNobel
Satellite Cells and the Muscle Stem Cell Niche
2013 Standout
MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands
2010 StandoutNobel
Regulation of Myosin Phosphatase by Rho and Rho-Associated Kinase (Rho-Kinase)
1996 StandoutScience
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
Multiple Click-Selective tRNA Synthetases Expand Mammalian Cell-Specific Proteomics
2018 StandoutNobel
Works of Mark Lee being referenced
Genetic Analysis of the Role of Pol II Holoenzyme Components in Repression by the Cyc8-Tup1 Corepressor in Yeast
2000
Pancreatic acinar cells: Use of a Ca++ ionophore to separate enzyme release from the earlier steps in stimulus-secretion coupling
1974
Increased Wnt Signaling During Aging Alters Muscle Stem Cell Fate and Increases Fibrosis
2007 StandoutScience
Wnts as Essential Growth Factors for the Adult Small Intestine and Colon
2004
Developmental and molecular characterization of mutations in the Drosophila-raf serine/threonine protein kinase
1993
Essential requirement for Wnt signaling in proliferation of adult small intestine and colon revealed by adenoviral expression of Dickkopf-1
2003