Standout Papers
Citation Impact
Citing Papers
Olefin Cyclopropanation via Carbene Transfer Catalyzed by Engineered Cytochrome P450 Enzymes
2012 StandoutScienceNobel
Potassium t -Butoxide Alone Can Promote the Biaryl Coupling of Electron-Deficient Nitrogen Heterocycles and Haloarenes
2008
The Catalytic Cross-Coupling of Unactivated Arenes
2007 Science
Oxindole Synthesis by Direct Coupling of CH and CH Centers
2009
Synthetic Methods for the Generation and Preparative Application of Benzyne
2010
Iron-catalyzed aryl-aryl cross coupling route for the synthesis of 1-(2-amino)-phenyl)dibenzo[b,d]furan-2-ol derivatives and their biological evaluation
2013
Direct arylations of electron-deficient (hetero)arenes with aryl or alkenyl tosylates and mesylates
2010
Directed Amination of Non‐Acidic Arene CH Bonds by a Copper–Silver Catalytic System
2013
Postsynthetic Modification of Peptides: Chemoselective C‐Arylation of Tryptophan Residues
2009
Ruthenium(II)‐Catalyzed Oxidative CH Alkenylations of Sulfonic Acids, Sulfonyl Chlorides and Sulfonamides
2014
Decarboxylative alkenylation
2017 Nature
One‐Step Synthesis of the Benzocyclo[penta‐ to octa‐]isoindole Core
2009
Palladium‐Catalyzed Intramolecular C(sp3)H Functionalization: Catalyst Development and Synthetic Applications
2006
Total synthesis of bryostatin 16 using atom-economical and chemoselective approaches
2008 Nature
Friedel–Crafts Arylation for the Formation of CC Bonds: A Route to Unsymmetrical and Functionalized Polycyclic Aromatic Hydrocarbons from Aryl Triazenes
2012
The first iron-catalysed aluminium-variant Negishi coupling: critical effect of co-existing salts on the dynamic equilibrium of arylaluminium species and their reactivity
2010
Mechanisms of C–H bond activation: rich synergy between computation and experiment
2009
Allylic CH Alkylation of Unactivated α‐Olefins: Serial Ligand Catalysis Resumed
2011
Recyclable Catalysts for Palladium‐Catalyzed Aminations of Aryl Halides
2011
Catalytic Functionalization of C(sp2)H and C(sp3)H Bonds by Using Bidentate Directing Groups
2013 Standout
Copper‐Mediated Direct Cross‐Coupling of 1,3,4‐Oxadiazoles and Oxazoles with Terminal Alkynes
2010
Highly diastereoselective Csp3–Csp2 Negishi cross-coupling with 1,2-, 1,3- and 1,4-substituted cycloalkylzinc compounds
2010
Iron‐Catalyzed Carbonylation: Selective and Efficient Synthesis of Succinimides
2009
Cobalt‐Catalyzed CH Bond Functionalizations with Aryl and Alkyl Chlorides
2013
Rhodium-Catalyzed C–H Bond Arylation of Arenes
2009
Total Synthesis of Apicularen A through Transannular Pyran Formation
2004
Ruthenium‐Catalyzed Direct Arylations of N‐Aryl 1,2,3‐Triazoles with Aryl Chlorides as Electrophiles
2009
Diastereoselective Temporary Silicon‐Tethered Ring‐Closing‐Metathesis Reactions with Prochiral Alcohols: A New Approach to Long‐Range Asymmetric Induction
2003
The syntheses and catalytic applications of unsymmetrical ferrocene ligands
2004
Palladium‐Catalyzed Allylic Fluorination
2011
Intermolecular oxidative cross-coupling of arenes
2009
C–H nitrogenation and oxygenation by ruthenium catalysis
2013
Enantioselective Iridium‐Catalyzed Allylic Arylation
2008
Palladium‐Catalyzed Direct Arylations of Heteroarenes with Tosylates and Mesylates
2008
Cobalt‐Catalyzed CH Arylations with Weakly‐Coordinating Amides and Tetrazoles: Expedient Route to Angiotensin‐II‐Receptor Blockers
2015
RuCl3⋅x H2O‐Catalyzed Direct Arylation of Arenes with Aryl Chlorides in the Presence of Triphenylphosphine
2009
Nickel-catalyzed C–H direct amination of benzoxazoles with secondary amines
2012
Mild Copper‐Catalyzed Fluorination of Alkyl Triflates with Potassium Fluoride
2014
C–C, C–O and C–N bond formation via rhodium(iii)-catalyzed oxidative C–H activation
2012 Standout
Iridium(I)-catalyzed regio- and enantioselective allylic amidation
2007
A convenient synthesis of anthranilic acids by Pd-catalyzed direct intermolecular ortho-C–H amidation of benzoic acids
2012
Cross-Dehydrogenative Coupling Reactions of sp3-Hybridized C–H Bonds
2009
Rhodium‐Catalyzed Oxidative Coupling between Salicylaldehydes and Internal Alkynes with CH Bond Cleavage To Produce 2,3‐Disubstituted Chromones
2008
Catalytic Asymmetric Intramolecular Hydroarylations of ω‐Aryloxy‐ and Arylamino‐Tethered α,β‐Unsaturated Aldehydes
2009
Palladium(II)‐Catalyzed Oxidative CH/CH Cross‐Coupling between Two Structurally Similar Azoles
2012
Suzuki–Miyaura Coupling Reaction by PdII‐Catalyzed Aromatic CH Bond Activation Directed by an N‐Alkyl Acetamino Group
2007
Indoles from Simple Anilines and Alkynes: Palladium‐Catalyzed CH Activation Using Dioxygen as the Oxidant
2009
Copper-mediated oxidative direct C–C (hetero)aromatic cross-coupling
2012
Copper‐Catalyzed Direct C Arylation of Heterocycles with Aryl Bromides: Discovery of Fluorescent Core Frameworks
2009
Synthesis of π-extended porphyrins via intramolecular oxidative coupling
2012
Stereospecific Copper‐Catalyzed CH Allylation of Electron‐Deficient Arenes with Allyl Phosphates
2011
Combinatorial and computational challenges for biocatalyst design
2001 StandoutNatureNobel
Pd(ii)-catalyzed direct C5-arylation of azole-4-carboxylates through double C–H bond cleavage
2012
Gold‐Catalyzed [4C+3C] Intramolecular Cycloaddition of Allenedienes: Synthetic Potential and Mechanistic Implications
2009
Recent advances in homogeneous nickel catalysis
2014 StandoutNature
Nickel-catalyzed sp2 C–H bonds arylation of N-aromatic heterocycles with Grignard reagents at room temperature
2011
Cobalt‐Catalyzed Direct Arylation of Unactivated Arenes with Aryl Halides
2011
Copper‐Catalyzed Direct Carboxylation of CH Bonds with Carbon Dioxide
2010
CH Bond Functionalization: Emerging Synthetic Tools for Natural Products and Pharmaceuticals
2012 Standout
Palladium Complexes of N‐Heterocyclic Carbenes as Catalysts for Cross‐Coupling Reactions—A Synthetic Chemist's Perspective
2007 Standout
Metal-catalyzed direct alkylations of (hetero)arenes via C–H bond cleavages with unactivated alkyl halides
2010
Friedel–Crafts Reaction of Benzyl Fluorides: Selective Activation of CF Bonds as Enabled by Hydrogen Bonding
2014
Nickel‐Catalyzed CH Arylation of Azoles with Haloarenes: Scope, Mechanism, and Applications to the Synthesis of Bioactive Molecules
2011
Tandem CH Activation/Arylation Catalyzed by Low‐Valent Iron Complexes with Bisiminopyridine Ligands
2014
Palladium/Copper‐Catalyzed Oxidative CH Alkenylation/N‐Dealkylative Carbonylation of Tertiary Anilines
2013
Amide-directed arylation of sp3 C–H bonds using Pd(II) and Pd(0) catalysts
2010
A core-extended naphthalene diimide as a p-channel semiconductor
2011
Rhodium‐Catalyzed Asymmetric 1,6‐Addition of Aryl Zinc Reagents to Dienones
2005
Nickel‐ and Cobalt‐Catalyzed Direct Alkylation of Azoles with N‐Tosylhydrazones Bearing Unactivated Alkyl Groups
2011
Organotrifluoroborates and Monocoordinated Palladium Complexes as Catalysts—A Perfect Combination for Suzuki–Miyaura Coupling
2009
Palladium(0)‐Catalyzed Intermolecular Amination of Unactivated CH Bonds
2011
Pd II ‐Catalyzed Monoselective ortho Halogenation of CH Bonds Assisted by Counter Cations: A Complementary Method to Directed ortho Lithiation
2008
A facile route to isoflavone quinones via the direct cross-coupling of chromones and quinones
2012
α‐Sulfonyl Succinimides: Versatile Sulfinate Donors in Fe‐Catalyzed, Salt‐Free, Neutral Allylic Substitution
2011
The rational design of potential chemotherapeutic agents: Synthesis of bryostatin analogues
1999
An Efficient Palladium‐Catalyzed CH Alkoxylation of Unactivated Methylene and Methyl Groups with Cyclic Hypervalent Iodine (I3+) Oxidants
2013
Asymmetric Synthesis of Diarylmethyl Amines by Rhodium‐Catalyzed Asymmetric Addition of Aryl Titanium Reagents to Imines
2004
An efficient organocatalytic method for constructing biaryls through aromatic C–H activation
2010
Ruthenium‐Catalyzed Reactions—A Treasure Trove of Atom‐Economic Transformations
2005
Recent Applications of Chiral Ferrocene Ligands in Asymmetric Catalysis
2006
Catalytic C–H amination: recent progress and future directions
2009
Striking AcOH Acceleration in Direct Intramolecular Allylic Amination Reactions
2009
Direct Application of Phenolic Salts to Nickel‐Catalyzed Cross‐Coupling Reactions with Aryl Grignard Reagents
2010
Constructing Multiply Substituted Arenes Using Sequential Palladium(II)‐Catalyzed CH Olefination
2010
Palladium‐ and Nickel‐Catalyzed Direct Alkylation of Azoles with Unactivated Alkyl Bromides and Chlorides
2010
Recent developments and perspectives in palladium-catalyzed cyanation of aryl halides: synthesis of benzonitriles
2011
Alkyl–Alkyl Suzuki Cross‐Coupling of Unactivated Secondary Alkyl Chlorides
2010
Introduction of Fluorine and Fluorine‐Containing Functional Groups
2013 Standout
Direct Arylation of Thiazoles on Water
2007
Metal‐ and Reagent‐Free Highly Selective Anodic Cross‐Coupling Reaction of Phenols
2014
Ru-catalyzed aerobic oxidative coupling of arylboronic acids with arenes
2010
Direct Alkynylation of Indole and Pyrrole Heterocycles
2009
Mutual Activation: Suzuki–Miyaura Coupling through Direct Cleavage of the sp2 CO Bond of Naphtholate
2011
Tandem Catalytic C(sp3)H Amination/Sila‐Sonogashira–Hagihara Coupling Reactions with Iodine Reagents
2015
Tandem intramolecular benzyne–furan cycloadditions. Total synthesis of vineomycinone B2 methyl ester
2007
Diastereoselective Carbometalation of Oxa‐ and Azabicyclic Alkenes under Iron Catalysis
2010
Chiral Bidentate Bis(N‐Heterocyclic Carbene)‐Based Palladium Complexes Bearing Carboxylate Ligands: Highly Effective Catalysts for the Enantioselective Conjugate Addition of Arylboronic Acids to Cyclic Enones
2008
A Versatile Palladium/Triphosphane System for Direct Arylation of Heteroarenes with Chloroarenes at Low Catalyst Loading
2010
Nickel-catalyzed alkyne annulation by anilines: versatile indole synthesis by C–H/N–H functionalization
2013
Regioselective syntheses of fully-substituted 1,2,3-triazoles: the CuAAC/C–H bond functionalization nexus
2010
Isolation, Structure, and Reactivity of an Arylnickel(II) Pivalate Complex in Catalytic C–H/C–O Biaryl Coupling
2013
Copper‐Catalyzed One‐Pot Synthesis of Imidazo/Benzoimidazoquinazolinones by Sequential Ullmann‐Type Coupling and Intramolecular CH Amidation
2011
Cycloisomerization of 1,n‐Enynes: Challenging Metal‐Catalyzed Rearrangements and Mechanistic Insights
2008
Cobalt‐Catalyzed Direct Arylation and Benzylation by CH/CO Cleavage with Sulfamates, Carbamates, and Phosphates
2012
Palladium and Copper Catalysis in Regioselective, Intermolecular Coupling of C–H and C–Hal Bonds
2009
Direct arylations on water: synthesis of 2,5-disubstituted oxazoles balsoxin and texaline
2008
Iron‐Catalyzed Direct Arylation of Unactivated Arenes with Aryl Halides
2010
Palladium(II)‐Catalyzed CH Activation/CC Cross‐Coupling Reactions: Versatility and Practicality
2009 Standout
Iron-catalysed aziridination reactions promoted by an ionic liquid
2008
Palladium‐Catalyzed Carbonylation Reactions of Aryl Halides and Related Compounds
2009
Palladium‐Catalyzed Direct Arylation of Cyclic Enamides with Aryl Silanes by sp2 CH Activation
2009
A Highly Para‐Selective Copper(II)‐Catalyzed Direct Arylation of Aniline and Phenol Derivatives
2010
Tuning the Reactivity of Dirhodium(II) Complexes with Axial N‐Heterocyclic Carbene Ligands: The Arylation of Aldehydes
2007
Ortho-directed functionalization of arenes using magnesate bases
2010
Catalytic Asymmetric Tandem Transformations Triggered by Conjugate Additions
2005
Ruthenium‐Catalyzed Hydroarylation of Methylenecyclopropanes through CH Bond Cleavage: Scope and Mechanism
2012
Oxidative Coupling of Aromatic Substrates with Alkynes and Alkenes under Rhodium Catalysis
2010 Standout
Enantioselective rhodium-catalyzed addition of arylboronic acids to trifluoromethyl ketones
2006 StandoutNobel
Recent advances in the transition metal-catalyzed twofold oxidative C–H bond activation strategy for C–C and C–N bond formation
2011 Standout
Computational study of ethene hydroarylation at [Ir(κ2-OAc)(PMe3)Cp]+
2010
Highly Efficient and Regioselective Platinum(II)‐Catalyzed Tandem Synthesis of Multiply Substituted Indolines and Tetrahydroquinolines
2009
Chemistry and clinical biology of the bryostatins
2000
Microwave‐Assisted Palladium‐Catalyzed Direct Arylation of 1,4‐Disubstituted 1,2,3‐Triazoles with Aryl Chlorides
2007
Synthesis of Extended π‐Systems through C–H Activation
2014 Standout
Multiple CH Activations To Construct Biologically Active Molecules in a Process Completely Free of Organohalogen and Organometallic Components
2007
Fe-catalysed oxidative C–H functionalization/C–S bond formation
2011
Palladium‐Catalyzed Cross‐Coupling: A Historical Contextual Perspective to the 2010 Nobel Prize
2012 Standout
Formation of pentacyclic structures by a domino sequence on cyclic enamides
2009
A Versatile Iron‐Catalyzed Protocol for the One‐Pot Synthesis of Isoxazoles or Isoxazolines from the Same Propargylic Alcohols
2010
Synthesis of Phenanthridinones from N‐Methoxybenzamides and Aryltriethoxysilanes through RhIII‐Catalyzed CH and NH Bond Activation
2013
Transition-metal-catalyzed C–C bond formation through the fixation of carbon dioxide
2011
Combining Rhodium and Photoredox Catalysis for CH Functionalizations of Arenes: Oxidative Heck Reactions with Visible Light
2014
Rhodium‐Mediated Decarboxylative Conjugate Addition of Fluorinated Benzoic Acids: Stoichiometric and Catalytic Transformations
2009
Mechanism of electrophilic fluorination with Pd(iv ): fluoride capture and subsequent oxidative fluoride transfer
2013
Enzymatic assembly of carbon–carbon bonds via iron-catalysed sp3 C–H functionalization
2018 StandoutNatureNobel
Functionalization of Organic Molecules by Transition‐Metal‐Catalyzed C(sp3)H Activation
2010
Iron oxide mediated direct C–H arylation/alkylation at α-position of cyclic aliphatic ethers
2011
Direct Arylation of 6‐Phenylpurine and 6‐Arylpurine Nucleosides by Ruthenium‐Catalyzed CH Bond Activation
2011
Strategies in Organic Synthesis for Condensed Arenes, Coronene, and Graphene
2013
Transition metal-catalyzed N-arylations of amidines and guanidines
2012
Low‐Temperature Iron‐Catalyzed Depolymerization of Polyethers
2012
Synthesis of Indolines and Tetrahydroisoquinolines from Arylethylamines by PdII‐Catalyzed CH Activation Reactions
2008
Rhodium(III) and Hexabromobenzene—A Catalyst System for the Cross‐Dehydrogenative Coupling of Simple Arenes and Heterocycles with Arenes Bearing Directing Groups
2012
Gold(I )‐Catalyzed Cyclizations of 1,6‐Enynes: Alkoxycyclizations and exo/endo Skeletal Rearrangements
2005
Palladium‐Catalyzed Direct Functionalization of 2‐Aminobutanoic Acid Derivatives: Application of a Convenient and Versatile Auxiliary
2013
Copper‐Mediated ortho‐Nitration of (Hetero)Arenecarboxylates
2014
Regioselective palladium-catalyzed direct cross-coupling of coumarins with simple arenes
2012
Rhodium(III)‐Catalyzed CH Activation of Arenes Using a Versatile and Removable Triazene Directing Group
2012
Nickel/Bis(oxazoline)-Catalyzed Asymmetric Kumada Reactions of Alkyl Electrophiles: Cross-Couplings of Racemic α-Bromoketones
2010
Iron‐Catalyzed Chemoselective ortho Arylation of Aryl Imines by Directed CH Bond Activation
2009
Direct Cross‐Coupling of CH Bonds with Grignard Reagents through Cobalt Catalysis
2010
Recyclable Solid Ruthenium Catalysts for the Direct Arylation of Aromatic CH Bonds
2010
Ruthenium(II)‐Catalyzed CH Alkenylations of Phenols with Removable Directing Groups
2013
Recyclable copper catalyzed nitrogenation of biphenyl halides: a direct approach to carbazoles
2013
Transition‐Metal‐Catalyzed π‐Bond‐Assisted CH Bond Functionalization: An Emerging Trend in Organic Synthesis
2015
Domino NH/CH Bond Activation: Palladium‐Catalyzed Synthesis of Annulated Heterocycles Using Dichloro(hetero)arenes
2007
Mechanistic Understanding of the Unexpected Meta Selectivity in Copper-Catalyzed Anilide C–H Bond Arylation
2011
Iridium(III)‐Catalyzed CH Amidation of Arylphosphoryls Leading to a P‐Stereogenic Center
2014
Cobalt-catalyzed cross-coupling reactions
2008
Efficient cross-coupling of aryl Grignard reagents with alkyl halides by recyclable ionic iron(iii) complexes bearing a bis(phenol)-functionalized benzimidazolium cation
2013
Palladium‐Catalyzed Double CH Activation Directed by Sulfoxides in the Synthesis of Dibenzothiophenes
2011
Mechanistic Study of a Switch in the Regioselectivity of Hydroheteroarylation of Styrene Catalyzed by Bimetallic Ni–Al through CH Activation
2014
A Convenient Synthesis of N‐Aryl Benzamides by Rhodium‐Catalyzed ortho‐Amidation and Decarboxylation of Benzoic Acids
2014
Ruthenium‐Catalyzed Oxidative Annulation by Cleavage of CH/NH Bonds
2011
New method for C–H arylation/alkylation at α-position of cyclic aliphatic ethers by iron-oxide mediated reaction
2012
CH Activation: A Complementary Tool in the Total Synthesis of Complex Natural Products
2012
Copper‐Mediated C6‐Selective Dehydrogenative Heteroarylation of 2‐Pyridones with 1,3‐Azoles
2014
Nickel‐Catalyzed Reductive Cyclizations and Couplings
2004
Heterocycle Formation via Palladium-Catalyzed C-H Functionalization
2012
Ruthenium-catalyzed oxidative C–H alkenylation of aryl carbamates
2012
Regioselective Iron‐Catalyzed Allylic Amination
2006
Nickel‐Catalyzed Three‐Component Coupling between Aryl Aldehydes, Norbornenes, and Silanes Leading to Indanols through Aromatic CH Bond Activation of Aryl Aldehydes
2011
Click Chemistry: Diverse Chemical Function from a Few Good Reactions
2001 StandoutNobel
The Catalytic Ability of Various Transition Metals in the Direct Functionalization of Aromatic CH Bonds
2011
Asymmetric Hydrogenation of Quinolines and Isoquinolines Activated by Chloroformates
2006
Gold(I)‐Catalyzed Intermolecular Cyclopropanation of Enynes with Alkenes: Trapping of Two Different Gold Carbenes
2006
Iron‐Catalyzed Synthesis of 2‐Vinylquinolines via sp3 CH Functionalization and Subsequent CN Cleavage
2013
Fused Indolines by Palladium‐Catalyzed Asymmetric CC Coupling Involving an Unactivated Methylene Group
2011
Mild Copper‐Mediated Direct Oxidative Cross‐Coupling of 1,3,4‐Oxadiazoles with Polyfluoroarenes by Using Dioxygen as Oxidant
2013
Metal‐Catalyzed Enantioselective Allylation in Asymmetric Synthesis
2007 Standout
The Mechanisms of the Stille Reaction
2004
Recent advances in aryl–aryl bond formation by direct arylation
2009
Diastereoselective metal-catalyzed [4 + 2 + 2] carbocyclization reactions utilizing a rhodium N-heterocyclic carbene (NHC) complex: the first example of a rhodium NHC-catalyzed [m+n+o] carbocyclization
2004
Mechanistic Study on Ligand‐Controlled Cobalt‐Catalyzed Regioselectivity‐Switchable Hydroarylation of Styrenes
2013
CH Alkenylations with Alkenyl Acetates, Phosphates, Carbonates, and Carbamates by Cobalt Catalysis at 23 °C
2015
The Nickel/Copper‐Catalyzed Direct Alkylation of Heterocyclic CH Bonds
2010
Room‐Temperature Palladium‐Catalyzed CH Activation: ortho‐Carbonylation of Aniline Derivatives
2009
Copper-catalyzed direct thiolation of azoles with aliphatic thiols
2011
Advances in Functional‐Group‐Tolerant Metal‐Catalyzed Alkyl–Alkyl Cross‐Coupling Reactions
2003
Diastereocontrol in the Synthesis of Models of Rings C and D of Phorbol: Directing Effect of an Ether Substituent on Lithium Carbenoid Mediated Cyclopropanation
2001
First intramolecular enantioselective iridium-catalysed allylic aminations
2004
Palladium‐Catalyzed Amidation of Unactivated C(sp3)H Bonds: from Anilines to Indolines
2009
Applications of and alternatives to π-electron-deficient azine organometallics in metal catalyzed cross-coupling reactions
2007
An Efficient and General Method for the Synthesis of α,ω‐Difunctional Reduced Polypropionates by Zr‐Catalyzed Asymmetric Carboalumination: Synthesis of the Scyphostatin Side Chain
2004 StandoutNobel
Phosphine‐Free, Palladium‐Catalyzed Arylation of Heterocycles through CH Bond Activation with Pivalic Acid as a Cocatalyst
2008
Readily Removable Directing Group Assisted Chemo‐ and Regioselective C(sp 3 )H Activation by Palladium Catalysis
2015
Fe‐Catalyzed Multicomponent Reactions: The Regioselective Alkoxy Allylation of Activated Olefins and its Application in Sequential Fe Catalysis
2012
Iron-catalyzed oxidative coupling of arylboronic acids with benzene derivatives through homolytic aromatic substitution
2011
Pd-catalyzed oxidative coupling with organometallic reagents via C–H activation
2010
Rhodium(II)‐Catalyzed Nondirected Oxidative Alkenylation of Arenes: Arene Loading at One Equivalent
2014
Palladium‐Catalyzed Oxidative Cyclization of N‐Aryl Enamines: From Anilines to Indoles
2008
AuI‐Catalyzed Tandem [3,3] Rearrangement–Intramolecular Hydroarylation: Mild and Efficient Formation of Substituted Indenes
2006
DFT study of the mechanism of benzocyclobutene formation by palladium-catalysed C(sp3)–H activation: role of the nature of the base and the phosphine
2010
Total Synthesis and Structural Elucidation of (−)‐Delactonmycin
2003
Palladium‐Catalyzed Dehydrogenative Cross‐Couplings of Benzazoles with Azoles
2011
Copper-catalyzed aromatic C–H bond halogenation with lithium halides under aerobic conditions
2013
On the Importance of an Acid Additive in the Synthesis of Pyrido[1,2‐a]benzimidazoles by Direct Copper‐Catalyzed Amination
2011
Copper‐Mediated and Copper‐Catalyzed Cross‐Coupling of Indoles and 1,3‐Azoles: Double CH Activation
2012
Sp–sp3 C–C bond formation via Fe(OTf)3/TfOH cocatalyzed coupling reaction of terminal alkynes with benzylic alcohols
2009
Oxidative Cross‐Coupling of Arenes Induced by Single‐Electron Transfer Leading to Biaryls by Use of Organoiodine(III) Oxidants
2007
Fe-catalyzed highly selective ring expansion of alkynylcyclopropyl alkanols to cyclobutanols
2009
Stereoselective Total Synthesis of (−)‐Borrelidin
2004
Novel [3+2] Cycloaddition of Alkylidenecyclopropanes with Aldehydes Catalyzed by Palladium
2001
Phosphoramidites: Privileged Ligands in Asymmetric Catalysis
2010 StandoutNobel
Regioselective Functionalization of Core‐Persubstituted Perylene Diimides
2014
Mechanistic aspects of transition metal catalysed 1,6-diene and 1,6-enyne cycloisomerisation reactions
2002
Direct transition metal-catalyzed functionalization of heteroaromatic compounds
2007 Standout
A Ligand‐Library Approach to the Highly Efficient Rhodium/Phosphoramidite‐Catalyzed Asymmetric Arylation of N,N‐Dimethylsulfamoyl‐Protected Aldimines
2006 StandoutNobel
Rhodium-catalyzed oxidative coupling of aromatic imines with internal alkynes via regioselective C–H bond cleavage
2009
Use of a Readily Removable Auxiliary Group for the Synthesis of Pyrrolidones by the Palladium‐Catalyzed Intramolecular Amination of Unactivated γ C(sp3)H Bonds
2013
Zinc-mediated CH-activation of tetrahydrofuran under mild conditions for the regioselective addition to aryl-propiolates
2014
Palladium catalyzed arylation for the synthesis of polyarenes
2007
Ruthenium-Catalyzed Oxidative Heck Reactions
2002
Easily Accessible Auxiliary for Palladium‐Catalyzed Intramolecular Amination of C(sp2)H and C(sp3)H Bonds at δ‐ and ε‐Positions
2014
Regioselective synthesis of isocoumarins by ruthenium-catalyzed aerobic oxidative cyclization of aromatic acids with alkynes
2011
Iron‐Catalyzed C(sp3)C(sp3) Bond Formation through C(sp3)H Functionalization: A Cross‐Coupling Reaction of Alcohols with Alkenes
2009
Deprotonative Metalation of Substituted Benzenes and Heteroaromatics Using Amino/Alkyl Mixed Lithium–Zinc Combinations
2010
Direct dehydrative cross-coupling of tautomerizable heterocycles with alkynes via Pd/Cu-catalyzed phosphonium coupling
2010
The chemistry and biology of the bryostatin antitumour macrolides
2002
PdII‐Catalyzed Enantioselective Activation of C(sp2)H and C(sp3)H Bonds Using Monoprotected Amino Acids as Chiral Ligands
2008
Organopalladium(iv) chemistry
2009
Carbonates: Ecofriendly Solvents for Palladium‐Catalyzed Direct 2‐Arylation of Oxazole Derivatives
2009
Palladium(II)‐Catalyzed ortho Alkylation of Benzoic Acids with Alkyl Halides
2009
Addressing Challenges in Palladium‐Catalyzed Cross‐Coupling Reactions Through Ligand Design
2012
Copper‐Catalyzed CC Bond Formation through CH Functionalization: Synthesis of Multisubstituted Indoles from N‐Aryl Enaminones
2009
Amidines for Versatile Ruthenium(II)‐Catalyzed Oxidative CH Activations with Internal Alkynes and Acrylates
2014
Elements of Regiocontrol in the Direct Heteroarylation of Indoles/Pyrroles: Synthesis of Bi‐ and Fused Polycyclic Heteroarenes by Twofold or Tandem Fourfold CH Activation
2012
Nickel catalyzed alkylation of N-aromatic heterocycles with Grignard reagents through direct C–H bond functionalization
2012
Fluorous silica gel-supported perfluoro-tagged palladium nanoparticles: an efficient and reusable catalyst for direct C-2 arylation of indoles
2010
Ruthenium‐Catalyzed Oxidative Cross‐Coupling of Chelating Arenes and Cycloalkanes
2008
Palladium‐Catalyzed Annulation of Acyloximes with Arynes (or Alkynes): Synthesis of Phenanthridines and Isoquinolines
2008
Ruthenium‐Catalyzed Isoquinolone Synthesis through CH Activation Using an Oxidizing Directing Group
2011
Ni-Catalyzed C–C Couplings Using Alkyl Electrophiles
2016
Arylnaphthalene Lignans through Pd‐Catalyzed [2+2+2] Cocyclization of Arynes and Diynes: Total Synthesis of Taiwanins C and E
2004
Pd-Catalyzed C–H Bond Functionalization on the Indole and Pyrrole Nucleus
2009
Pd-catalysed regioselective C–H functionalisation of 2-pyrones
2010
Recent Progress in Coupling of Two Heteroarenes
2011
Copper(ii)-catalyzed ortho-functionalization of 2-arylpyridines with acyl chlorides
2011
Transition metal-catalyzed arylation of unactivated C(sp3)–H bonds
2011
Regio‐ and Chemoselective Metalation of Arenes and Heteroarenes Using Hindered Metal Amide Bases
2011
Palladium-catalyzed direct oxidative Heck–Cassar–Sonogashira type alkynylation of indoles with alkynes under oxygen
2010
Nonnatural Amino Acid Synthesis by Using Carbon–Hydrogen Bond Functionalization Methodology
2012
FeCl3-Mediated synthesis of polysubstituted tetrahydroquinolines via domino Mannich/Friedel–Crafts reactions of aldehydes and amines
2011
Biaryl Phosphane Ligands in Palladium‐Catalyzed Amination
2008 Standout
Cobalt‐Catalyzed Isomerization of 1‐Alkenes to (E)‐2‐Alkenes with Dimethylphenylsilylmethylmagnesium Chloride and Its Application to the Stereoselective Synthesis of (E)‐Alkenylsilanes
2009
Palladium-catalyzed direct arylation of simple arenes in synthesis of biaryl molecules
2006
Nickel‐Catalyzed Direct CH Arylation and Alkenylation of Heteroarenes with Organosilicon Reagents
2010
Ligand-free copper(i)-catalysed intramolecular direct C–H functionalization of azoles
2009
Regioselectivity and enantioselectivity in nickel-catalysed reductive coupling reactions of alkynes
2007
Rhodium(iii)-catalyzed allylic C–H bond amination. Synthesis of cyclic amines from ω-unsaturated N-sulfonylamines
2012
Iron‐Catalyzed CH Bond Activation for the ortho‐Arylation of Aryl Pyridines and Imines with Grignard Reagents
2011
Computed CH Acidity of Biaryl Compounds and Their Deprotonative Metalation by Using a Mixed Lithium/Zinc‐TMP Base
2013
Catalytic Asymmetric Total Synthesis of ent‐Hyperforin
2010
Transition‐Metal‐Catalyzed Direct Arylation of (Hetero)Arenes by CH Bond Cleavage
2009 Standout
Cross Dehydrogenative Arylation (CDA) of a Benzylic CH Bond with Arenes by Iron Catalysis
2009
Copper-catalyzed ortho-halogenation of protected anilines
2013
Palladium‐Catalyzed Direct Arylation of (Hetero)Arenes with Aryl Boronic Acids
2008
Ruthenium-Catalyzed Direct Arylations Through C–H Bond Cleavages
2009
Access to β‐Lactams by Enantioselective Palladium(0)‐Catalyzed C(sp3)H Alkylation
2014
Copper-catalyzed CuAAC/intramolecular C–H arylation sequence: Synthesis of annulated 1,2,3-triazoles
2012
DNA‐Based Catalytic Enantioselective Michael Reactions in Water
2007 StandoutNobel
Palladium‐Catalyzed C(sp3)H Activation: A Facile Method for the Synthesis of 3,4‐Dihydroquinolinone Derivatives
2014
CH Bond Functionalization in Water Catalyzed by Carboxylato Ruthenium(II) Systems
2010
A Direct CH/ArH Coupling Approach to Oxindoles, Thio‐oxindoles, 3,4‐Dihydro‐1 H‐quinolin‐2‐ones, and 1,2,3,4‐Tetrahydroquinolines
2014
Palladium‐Catalyzed Tandem Heck Reaction/CH Functionalization—Preparation of Spiro‐Indane‐Oxindoles
2008
FeCl3-catalyzed synthesis of functionally diverse dibenzo[b,f]oxepines and benzo[b]oxepines via alkyne–aldehyde metathesis
2013
Manganese‐Catalyzed Synthesis of cis‐β‐Amino Acid Esters through Organometallic CH Activation of Ketimines
2015
Ruthenium‐Catalyzed Regioselective Direct Alkylation of Arenes with Unactivated Alkyl Halides through CH Bond Cleavage
2009
A General and Selective Iron‐Catalyzed Aminocarbonylation of Alkynes: Synthesis of Acryl‐ and Cinnamides
2010
Ruthenium(IV) Alkylidenes as Precatalysts for Direct Arylations of Alkenes with Aryl Chlorides and an Application to Sequential Catalysis
2007
Synthesis and Determination of the Absolute Configuration of Cavicularin by a Symmetrization/Asymmetrization Approach
2013
CH Functionalization/CN Bond Formation: Copper‐Catalyzed Synthesis of Benzimidazoles from Amidines
2008
Aqueous Catalytic Pauson–Khand‐Type Reactions of Enynes with Formaldehyde: Transfer Carbonylation Involving an Aqueous Decarbonylation and a Micellar Carbonylation
2003
Efficient Synthesis of Biologically Interesting 3,4‐Diaryl‐Substituted Succinimides and Maleimides: Application of Iron‐Catalyzed Carbonylations
2010
A Theoretical Study on the Complete Catalytic Cycle of the Hetero‐Pauson–Khand‐Type [2+2+1] Cycloaddition Reaction of Ketimines, Carbon Monoxide and Ethylene Catalyzed by Iron Carbonyl Complexes
2003
Palladium‐Catalyzed Arylative Ring‐Opening Reactions of Norbornenols: Entry to Highly Substituted Cyclohexenes, Quinolines, and Tetrahydroquinolines
2010
Rh‐Catalyzed Enantioselective Conjugate Addition of Arylboronic Acids with a Dynamic Library of Chiral tropos Phosphorus Ligands
2006
Direct Azole Amination: CH Functionalization as a New Approach to Biologically Important Heterocycles
2010
Iron‐Mediated Direct Arylation of Unactivated Arenes
2008
Studies in catalytic C–H amination involving nitrene C–H insertion
2010
Tuning the Regioselectivity in the Palladium(II )‐Catalyzed Isomerization of Alkylidene Cyclopropyl Ketones: A Dramatic Salt Effect
2003
Palladium‐Catalyzed Ring‐Expansion Reaction of Indoles with Alkynes: From Indoles to Tetrahydroquinoline Derivatives Under Mild Reaction Conditions
2010
Copper‐Catalyzed Oxidative Arylation of Heteroarenes under Mild Conditions Using Dioxygen as the Sole Oxidant
2011
Rhenium‐Catalyzed Synthesis of 3‐Imino‐1‐isoindolinones by CH Bond Activation: Application to the Synthesis of Polyimide Derivatives
2013
Copper‐Catalyzed Direct Alkenylation ofN‐Iminopyridinium Ylides
2009
Beyond Directing Groups: Transition‐Metal‐Catalyzed CH Activation of Simple Arenes
2012 Standout
Sulfonamide‐Promoted Palladium(II)‐Catalyzed Alkylation of Unactivated Methylene C(sp3)H Bonds with Alkyl Iodides
2014
Copper(II)‐Catalyzed meta‐Selective Direct Arylation of α‐Aryl Carbonyl Compounds
2010
Palladium(II)‐Catalyzed Regioselective Direct C2 Alkenylation of Indoles and Pyrroles Assisted by the N‐(2‐Pyridyl)sulfonyl Protecting Group
2009
Tuning Redox Chemistry and Photophysics in Core‐Substituted Tetraazaperopyrenes (TAPPs)
2013
Cross‐Coupling Reactions through the Intramolecular Activation of Alkyl(triorgano)silanes
2010
Recent advances in transition metal-catalyzed sp3C–H amination adjacent to double bonds and carbonyl groups
2011
Highly Enantioselective Palladium-Catalyzed Ene-Type Cyclization of a 1,6-Enyne
2001
Hydrofluorination of Alkynes Catalysed by Gold Bifluorides
2014
Nickel‐Catalyzed CH Alkylations: Direct Secondary Alkylations and Trifluoroethylations of Arenes
2014
Facile construction of highly functionalized 2-pyrrolines via FeCl3-catalyzed reaction of aziridines with arylalkynes
2009
Preformed π‐Allyl Iron Complexes as Potent, Well‐Defined Catalysts for the Allylic Substitution
2009
Aerobic Alcohol Oxidation Coupled to Palladium‐Catalyzed Alkene Hydroarylation with Boronic Esters
2008
Carboxylate Ligand-Induced Intramolecular C−H Bond Activation of Iridium Complexes withN-Phenylperimidine-Based Carbene Ligands
2010
Ruthenium(II)-Catalyzed Alkenylation of Ferrocenyl Ketones via C–H Bond Activation
2012
Chelation-assisted carbonylation reactions catalyzed by Rh and Ru complexes
2010
Regioselective synthesis of 3,3-bis(indolyl)propanoic acid derivatives by iron(III)-catalyzed hydroarylation of propynoic acid derivatives with indoles
2011
Iron-Catalyzed Reactions in Organic Synthesis
2004 Standout
Organocatalyzed Asymmetric Oxidative Coupling of α-Csp3-H of Tertiary Amines to α,β-Unsaturated γ-Butyrolactam: Synthesis of MBH-Type Products
2014
Sonogashira Reactions with Propyne: Facile Synthesis of 4-Hydroxy-2-methylbenzofurans from Iodoresorcinols
2009
Copper-Mediated Intermolecular Direct Biaryl Coupling
2011
Auto‐Tandem Catalysis: Synthesis of Substituted 11H‐Indolo[3,2‐c]quinolines via Palladium‐Catalyzed Intermolecular CN and Intramolecular CC Bond Formation
2008
Establishment of Broadly Applicable Reaction Conditions for the Palladium-Catalyzed Direct Arylation of Heteroatom-Containing Aromatic Compounds
2009
Analysis of the Concerted Metalation-Deprotonation Mechanism in Palladium-Catalyzed Direct Arylation Across a Broad Range of Aromatic Substrates
2008 Standout
Palladium-catalyzed oxidative C–H bond coupling of indoles and benzaldehydes: a new approach to the synthesis of 3-benzoylindoles
2013
Recent developments in asymmetric cyclopropanation
2008
Room Temperature and Phosphine Free Palladium Catalyzed Direct C-2 Arylation of Indoles
2008
Monofluorination of Organic Compounds: 10 Years of Innovation
2015 Standout
Direct C–H bond arylations and alkenylations with phenol-derived fluorine-free electrophiles
2012
Cross-coupling of E,E-1,4-diiodobuta-1,3-diene with nucleophiles catalyzed by Pd or Ni complexes: a new route to functionalized dienes
2001
Recent advances in the iron-catalyzed cycloaddition reactions
2012
Stereoselective Direct Copper-Catalyzed Alkenylation of Oxazoles with Bromoalkenes
2008
tert-Butoxide-Mediated Arylation of Benzene with Aryl Halides in the Presence of a Catalytic 1,10-Phenanthroline Derivative
2010
Ruthenium-Catalyzed Direct C–H Bond Arylations of Heteroarenes
2011
Iron-Catalyzed Regioselective Direct Oxidative Aryl–Aryl Cross-Coupling
2011
Iron Catalysis in Organic Synthesis
2015 Standout
Pd(II)-Catalyzed Cross-Coupling of sp3 C−H Bonds with sp2 and sp3 Boronic Acids Using Air as the Oxidant
2008
Copper-Mediated Coupling Reactions and Their Applications in Natural Products and Designed Biomolecules Synthesis
2008 Standout
Cooperative Catalysis with Aldehydes and Copper: Development and Application in Aerobic Oxidative CH Amination at Room Temperature
2013
Selectivity in palladium catalysed allylic substitution
1992
Rh(I)-Catalyzed Direct Arylation of Azines
2010
Metallkatalysierte enantioselektive Allylierungen in der asymmetrischen Synthese
2007
Mechanistic Studies on the Rh(III)-Mediated Amido Transfer Process Leading to Robust C–H Amination with a New Type of Amidating Reagent
2015
Cross‐Coupling of Heteroarenes by CH Functionalization: Recent Progress towards Direct Arylation and Heteroarylation Reactions Involving Heteroarenes Containing One Heteroatom
2014
Ruthenium‐Catalyzed Oxidative Homo‐Coupling of 2‐Arylpyridines
2009
Copper-Mediated Direct Arylation of 1,3,4-Oxadiazoles and 1,2,4-Triazoles with Aryl Iodides
2009
Ruthenium-Catalyzed Carbonylative Cycloaddition of α-Keto Lactones with Alkenes or Alkynes: The Participation of an Ester-Carbonyl Group in Cycloaddition Reactions as the Two-Atom Assembling Unit
2003
3d Transition Metals for C–H Activation
2018 Standout
Rigid, Sterically Diverse N-Heterocyclic Carbene-Pyridine Chelates: Synthesis, Mild Palladation, and Palladium-Catalyzed Allylic Substitution
2009
Copper-Catalyzed Direct C–H Oxidative Trifluoromethylation of Heteroarenes
2011
Modulating Reactivity and Diverting Selectivity in Palladium-Catalyzed Heteroaromatic Direct Arylation Through the Use of a Chloride Activating/Blocking Group
2010
Copper-catalyzed direct C–H fluoroalkenylation of heteroarenes
2015
Direct synthesis of highly fused perimidines by copper(I)-catalyzed hydroamination of 2-ethynylbenzaldehydes
2011
Transition-metal-catalyzed direct arylations via C–H bond cleavages
2010
N-heterocyclic carbene–palladium catalysts for the bisdiene cyclization-trapping reaction with sulfonamides under thermal and microwave conditions
2005
Controlled carbometalation as a new tool for carbon-carbon bond formation and its application to cyclization
1987 StandoutNobel
Asymmetric allylic alkylation catalyzed by palladium-sparteine complexes
1991
Palladium(II)-Catalyzed Direct Intermolecular Alkenylation of Chromones
2011
Highly efficient synthesis of polysubstituted fluorene via iron-catalyzed intramolecular Friedel–Crafts alkylation of biaryl alcohols
2012
Synthesis of chiral α-hydroxy acids via palladium-catalyzed C(sp3)–H alkylation of lactic acid
2015
Iron‐Catalyzed ortho Monoarylation of Benzamide Derivatives
2012
Palladium-catalyzed unactivated β-methylene C(sp3)–H bond alkenylation of aliphatic amides and its application in a sequential C(sp3)–H/C(sp2)–H bond alkenylation
2014
Highly Selective C−H Functionalization/Halogenation of Acetanilide
2006
Mild and Efficient Nickel-Catalyzed Heck Reactions with Electron-Rich Olefins
2011
Highly Efficient Alkyne Hydroarylation with Chelating Dicarbene Palladium(II) and Platinum(II) Complexes
2007
Metal−Organic Cooperative Catalysis in C−H and C−C Bond Activation and Its Concurrent Recovery
2008
Carboxylate‐Directed CH Functionalization
2014
Divergent copper-mediated dimerization and hydroxylation of benzamides involving C–H bond functionalization
2016
Rhodium-catalyzed enantioselective 1,4-additions of arylboronic acids to substituted enones
2006
Tri-Substituted Triazole-Enabled C–H Activation of Benzyl and Aryl Amines by Iron Catalysis
2017
Review of recent advances in nucleophilic C–F bond-forming reactions at sp3 centers
2014
Bond Formations between Two Nucleophiles: Transition Metal Catalyzed Oxidative Cross-Coupling Reactions
2011 Standout
Hydrogen-Bond-Assisted Controlled C–H Functionalization via Adaptive Recognition of a Purine Directing Group
2013
Proton-Abstraction Mechanism in the Palladium-Catalyzed Intramolecular Arylation: Substituent Effects
2007
Rhodium-Catalyzed Regioselective C−H Functionalization via Decarbonylation of Acid Chlorides and C−H Bond Activation under Phosphine-Free Conditions
2008
Search and Discovery Strategies for Biotechnology: the Paradigm Shift
2000
A Simple and Direct Method for the Palladium‐Catalyzed Oxidative Coupling of Unactivated Allylarenes with Classic Arenes
2014
Rh(III)-Catalyzed Directed C−H Olefination Using an Oxidizing Directing Group: Mild, Efficient, and Versatile
2011
Room-Temperature Chromium(II)-Catalyzed Direct Arylation of Pyridines, Aryl Oxazolines, and Imines Using Arylmagnesium Reagents
2014
Synthesis of Dictyopterene A: Optically Active Tributylstannylcyclopropane as a Chiral Synthon
2000
A Palladium‐Catalyzed Oxidative Cycloaromatization of Biaryls with Alkynes Using Molecular Oxygen as the Oxidant
2009
Direct arylation of azine N-oxides with aryl triflates
2009
Transition Metal Catalyzed [2+2+2] Cycloaddition and Application in Organic Synthesis
2005
Silver-Mediated Oxidative C–H/C–H Functionalization: A Strategy To Construct Polysubstituted Furans
2012
Palladium-Catalyzed Perarylation of 3-Thiophene- and 3-Furancarboxylic Acids Accompanied by C−H Bond Cleavage and Decarboxylation
2008
Application of Daugulis Copper-Catalyzed Direct Arylation to the Synthesis of 5-Aryl Benzotriazepines
2009
Synthesis of (−)-Epi-Indolactam V by an Intramolecular Buchwald–Hartwig C–N Coupling Cyclization Reaction
2013
Exploring new reactive species for cyclopropanation
1998
Cu(II)-Mediated Methylthiolation of Aryl C−H Bonds with DMSO
2010
Copper Phosphoramidite Catalyzed Enantioselective Ring-Opening of Oxabicyclic Alkenes: Remarkable Reversal of Stereocontrol
2002 StandoutNobel
Intramolecular Direct C–H Bond Arylation from Aryl Chlorides: A Transition-Metal-Free Approach for Facile Access of Phenanthridines
2012
Iodocyclopropanes as versatile intermediates for the synthesis of substituted cyclopropanes
1998
A New Oxidative Addition of Ruthenium(0) into an Aryl Halide Bond and Subsequent Intermolecular C−H Insertion
2009
Sc(OTf)3-Catalyzed Direct Alkylation of Quinolines and Pyridines with Alkanes
2009
2-(Trifluoromethyl)indoles via Pd(0)-Catalyzed C(sp3)–H Functionalization of Trifluoroacetimidoyl Chlorides
2016
Palladium-Catalyzed Aerobic Oxidative Cross-Coupling Reactions of Terminal Alkynes with Alkylzinc Reagents
2010
Polycyclic π-Electron System with Boron at Its Center
2012
Rhodium-Catalyzed Asymmetric Conjugate Additions of Boronic Acids Using Monodentate Phosphoramidite Ligands
2003 StandoutNobel
Palladium-Catalyzed Direct Arylations, Alkenylations, and Benzylations through C−H Bond Cleavages with Sulfamates or Phosphates as Electrophiles
2010
Carboxylate-Assisted Ruthenium-Catalyzed Direct Alkylations of Ketimines
2011
One-pot synthesis of diaryl ketones from aldehydes via palladium-catalyzed reaction with aryl boronic acids
2007
Copper‐Catalyzed Cross‐Dehydrogenative Coupling of N‐Iminoquinolinium Ylides with Secondary Amines
2016
Assembly of Indoline-2-carboxylate-Embodied Dipeptides via Pd-Catalyzed C(sp2)–H Bond Direct Functionalization
2015
Cu-Catalyzed Oxidative C(sp2)–H Cycloetherification ofo-Arylphenols for the Preparation of Dibenzofurans
2012
Palladium(0)/Copper(I)-Cocatalyzed Cross-Coupling of the Zinc Reagent of Ethyl 3-Bromo-3,3-difluoropropionate with Aryl (Alkenyl) Halides: An Efficient Stereoselective Synthesis of β-Fluoro-α,β-unsaturated Esters
2000
Palladium(II)‐Catalyzed Direct ortho‐CH Acylation of Anilides by Oxidative Cross‐Coupling with Aldehydes using tert‐Butyl Hydroperoxide as Oxidant
2011
Direct arylation of imidazo[2,1‐b]thiazoles and thiazoles with aryl iodides via CuCl2/PPh3‐catalyzed C–H bond functionalization
2015
Total Synthesis of (−)-N-Methylwelwitindolinone C Isothiocyanate
2011
Design and Synthesis of 2‐Methyl‐7‐aminobenzoxazole as Auxiliary in the Palladium(II)‐Catalyzed Arylation of a beta‐Positioned C(sp3)H Bond
2016
Catalytic Direct Arylations in Polyethylene Glycol (PEG): Recyclable Palladium(0) Catalyst for C−H Bond Cleavages in the Presence of Air
2009
Sequential Allylic C–H Amination/Vinylic C–H Arylation: A Strategy for Unnatural Amino Acid Synthesis from α-Olefins
2012
Palladium‐Catalyzed CF Bond Formation via Directed CH Activation
2014
Palladium(0)-catalyzed cyclopropane C–H bond functionalization: synthesis of quinoline and tetrahydroquinoline derivatives
2011
Recent advances in the synthesis of (hetero)aryl-substituted heteroarenes via transition metal-catalysed direct (hetero)arylation of heteroarene C–H bonds with aryl halides or pseudohalides, diaryliodonium salts, and potassium aryltrifluoroborates
2009
Copper-Catalyzed Cyanation of Heterocycle Carbon−Hydrogen Bonds
2010
Palladium-Catalyzed Decarboxylative Arylation of C−H Bonds by Aryl Acylperoxides
2009
Versatile Synthesis of Isocoumarins and α-Pyrones by Ruthenium-Catalyzed Oxidative C–H/O–H Bond Cleavages
2012
Systematic Study of Halide‐Induced Ring Opening of 2‐Substituted Aziridinium Salts and Theoretical Rationalization of the Reaction Pathways
2010
Towards Sustainable C−H Functionalization Reactions: The Emerging Role of Bio‐Based Reaction Media
2018
Asymmetric Suzuki Cross-Couplings of Activated Secondary Alkyl Electrophiles: Arylations of Racemic α-Chloroamides
2010
A Concise Update on the Applications of Chiral Ferrocenyl Phosphines in Homogeneous Catalysis Leading to Organic Synthesis
2003
Copper‐Catalyzed Direct CH Arylation of Thieno[3,4‐c]pyrrole‐4,6‐dione (TPD): Toward Efficient and Low‐Cost Synthesis of π‐Functional Small Molecules
2014
Diastereoselectivity in cyclopropanation and epoxidation reactions of chiral (E)-crotylsilanes: Asymmetric synthesis of substituted tetrahydrofurans
1994
Elements of Regiocontrol in Palladium-Catalyzed Oxidative Arene Cross-Coupling
2007 Standout
Rh(I)-Catalyzed Direct Arylation of Pyridines and Quinolines
2008
Electrocatalytic C–H Activation
2018
Copper-Mediated Oxidative Coupling of Benzamides with Maleimides via Directed C–H Cleavage
2015
Palladium-Catalyzed Alkenylation of Quinoline-N-oxides via C−H Activation under External-Oxidant-Free Conditions
2009
Direct Arylation of Primary and Secondary sp3 C–H Bonds with Diarylhyperiodonium Salts via Pd Catalysis
2013
Tosylhydrazide‐Promoted Palladium‐Catalyzed Reaction of β‐Aminoketones with o‐Dihaloarenes: Combining Organocatalysis and Transition‐Metal Catalysis
2011
Dehydrogenative [4 + 2] Cycloaddition of Formamides with Alkynes through Double C−H Activation
2011
Asymmetric Alkyl−Alkyl Cross-Couplings of Unactivated Secondary Alkyl Electrophiles: Stereoconvergent Suzuki Reactions of Racemic Acylated Halohydrins
2010
Iron-catalysed alkene hydrogenation and reductive cross-coupling using a bench-stable iron(ii) pre-catalyst
2013
Nitrogen-directed ortho-arylation and -heteroarylation of aromatic rings catalyzed by ruthenium complexes
2008
Synthesis of Sulfoximine‐Derived P,N Ligands and their Applications in Asymmetric Quinoline Hydrogenations
2008
Air-Stable Pd(R-allyl)LCl (L= Q-Phos, P(t-Bu)3, etc.) Systems for C–C/N Couplings: Insight into the Structure–Activity Relationship and Catalyst Activation Pathway
2011
Palladium-Catalyzed Direct Functionalization of Imidazolinone: Synthesis of Dibromophakellstatin
2007
Recent Advances in Palladium‐Catalyzed Cross‐Coupling Reactions at ppm to ppb Molar Catalyst Loadings
2017
Methods Utilizing First-Row Transition Metals in Natural Product Total Synthesis
2017
Transition metal catalyzed cycloaddition reactions of chiral ketimines with alkenes and carbon monoxide: reaction conditions, substrate variations and stereoselectivity
2003
Heterocycles from methylenecyclopropanes
2015
An In Situ Directing Group Strategy for Chiral Anion Phase-Transfer Fluorination of Allylic Alcohols
2014
Novel Rhodium-Catalyzed Cycloisomerization of 1,6-Enynes with an Intramolecular Halogen Shift
2003
Catalytic iron-mediated ene carbocyclizations: formal [4+4]-ene reactions of triene esters
1990
Palladium-Catalyzed Aryl–Aryl Bond Formation Through Double C–H Activation
2009
C−H Bond Activation of Heteroarenes Mediated by a Half-Sandwich Iron Complex of N-Heterocyclic Carbene
2008
Copper-Catalyzed Direct Amidation of Heterocycles withN-Fluorobenzenesulfonimide
2014
Iridium-Catalyzed C–H Amination with Anilines at Room Temperature: Compatibility of Iridacycles with External Oxidants
2014
Copper-Catalyzed Asymmetric Ring Opening of Oxabicyclic Alkenes with Grignard Reagents
2005
Recent Developments in Ruthenium-Catalyzed C–H Arylation: Array of Mechanistic Manifolds
2017
The chemo- and enantioselective cyclopropanation of polyenes: chiral auxiliary vs chiral reagent-based approach
1996
Iron-Catalysed C-3 Functionalisation of Indolizines via C–H Bond Cleavage
2012
Rhodium‐Mediated Decarboxylative Conjugate Addition of Fluorinated Benzoic Acids: Stoichiometric and Catalytic Transformations
2009
Enantioselective 1,4-addition of arylboronic acids to α,β-unsaturated carbonyl compounds catalyzed by rhodium(I)-chiral phosphoramidite complexes
2006
Pd-Catalyzed Dehydrogenative Cross-Coupling of Polyfluoroarenes with Heteroatom-Substituted Enones
2012
Copper-Mediated Cascade C–H/N–H Annulation of Indolocarboxamides with Arynes: Construction of Tetracyclic Indoloquinoline Alkaloids
2017
Copper‐Catalyzed or ‐Mediated CH Bond Functionalizations Assisted by Bidentate Directing Groups
2016
Copper-Catalyzed Arylation of β-Amino Alcohols
2002
Synthesis of Structurally Diverse Polyfunctional Pyrrolo[1,2‐a]quinolines by Sequential Iron‐Catalyzed Three‐Component Coupling and Gold‐Catalyzed Hydroarylation Reactions
2013
Efficient and highly regioselective direct C-2 arylation of azoles, including free (NH)-imidazole, -benzimidazole and -indole, with aryl halides
2006
Efficient Palladium-Catalyzed C–H Fluorination of C(sp3)–H Bonds: Synthesis of β-Fluorinated Carboxylic Acids
2015
Heterocycles as Key Substrates in Multicomponent Reactions: The Fast Lane towards Molecular Complexity
2008
Oxidative Coupling between Two Hydrocarbons: An Update of Recent C–H Functionalizations
2015 Standout
Synthesis and biological evaluation of a new class of bryostatin analogues: the role of the C20 substituent in protein kinase C binding
2000
Rh-catalyzed π-facial selective intermolecular hydroacylation of norbornenes
2005
Ruthenium(II)-Catalyzed Regio- and Stereoselective Hydroarylation of Alkynes via Directed C–H Functionalization
2012
Pd(OAc)2-Catalyzed Regioselective Arylation of Indoles with Arylsiloxane in Acidic Medium
2010
Transient Directing Groups for Transformative C–H Activation by Synergistic Metal Catalysis
2017
Ruthenium(II)-Catalyzed [2 + 2 + 2] Cycloaddition of 1,6-Diynes with Tricarbonyl Compounds
2002
Ruthenium-catalyzed Oxidative Alkenylation of Arenes via Regioselective C–H Bond Cleavage Directed by a Nitrogen-containing Group
2011
Stereoselective RhI-Catalyzed Tandem Conjugate Addition of Boronic Acids−Michael Cyclization
2007
Copper-Catalyzed Oxidative sp3 C−H Bond Arylation with Aryl Boronic Acids
2008
Pivalophenone imine as a benzonitrile surrogate for directed C–H bond functionalization
2017
Palladium(II)-Catalyzed Asymmetric Cyclization of (Z)-4‘-Acetoxy-2‘-butenyl 2-Alkynoates. Role of Nitrogen-Containing Ligands in Palladium(II)-Mediated Reactions
2001
Rh[III]-Catalyzed Direct C–H Amination Using N-Chloroamines at Room Temperature
2011
Cobalt(ii )-catalyzed chelation-assisted C–H iodination of aromatic amides with I2
2018
Site-Selective Azaindole Arylation at the Azine and Azole Rings via N-Oxide Activation
2009
Iridium catalysts for the asymmetric hydrogenation of olefins with nontraditional functional substituents
2007
Iron-Catalyzed Cross-Coupling of Unactivated Secondary Alkyl Thio Ethers and Sulfones with Aryl Grignard Reagents
2013
Pd(0)‐Catalyzed Bismetallative Cyclization of Enynes in the Presence of Bu3SnSiMe3 Using N‐Heterocyclic Carbene as a Ligand
2003
Nickel-Catalyzed Stereoselective Alkenylation of C(sp3)–H Bonds with Terminal Alkynes
2017
Cobalt(II)-Catalyzed Oxidative C–H Arylation of Indoles and Boronic Acids
2017
Diethyl carbonate as a solvent for ruthenium catalysed C–H bond functionalisation
2009
Copper-Catalyzed Aerobic Oxidative Intramolecular C–H Amination Leading to Imidazobenzimidazole Derivatives
2011
Rare-Earth Metal Triflates in Organic Synthesis
2002
Cu(II)-Catalyzed Direct and Site-Selective Arylation of Indoles Under Mild Conditions
2008
Robust Ruthenium(II)-Catalyzed C–H Arylations: Carboxylate Assistance for the Efficient Synthesis of Angiotensin-II-Receptor Blockers
2014
Rhodium(III)-Catalyzed Intermolecular Direct Amination of Aromatic C–H Bonds with N-Chloroamines
2011
Copper-mediated intramolecular aza-Wacker-type cyclization of 2-alkenylanilines toward 3-aryl indoles
2016
Copper-Catalyzed Formal [4 + 1] Cycloaddition of Benzamides and Isonitriles via Directed C–H Cleavage
2015
Synthesis of Tricyclic Nitrogen Heterocycles by a Sequence of Palladium-Catalyzed N–H and C(sp3)–H Arylations
2011
Direct Synthesis of N-H Carbazoles via Iridium(III)-Catalyzed Intramolecular C–H Amination
2015
Nano‐Iron Oxide as a Recyclable Catalyst for Intramolecular CN Cross‐Coupling Reactions under Ligand‐Free Conditions: One‐Pot Synthesis of 1,4‐Dihydroquinoline Derivatives
2009
Iron-Catalyzed Heterocycle and Arene Deprotonative Alkylation
2010
Carbon−Carbon Coupling Reactions Catalyzed by Heterogeneous Palladium Catalysts
2006 Standout
Coupling of benzyl halides with aryl Grignard reagents catalyzed by iron(III) amine-bis(phenolate) complexes
2013
Decarbonylative C–H Coupling of Azoles and Aryl Esters: Unprecedented Nickel Catalysis and Application to the Synthesis of Muscoride A
2012
Nickel-Catalyzed Ortho-Arylation of Unactivated (Hetero)aryl C–H Bonds with Arylsilanes Using a Removable Auxiliary
2016
Synergic effect of copper-based metal–organic frameworks for highly efficient C–H activation of amidines
2017
Direct Synthesis of Pyrazolo[5,1‐a]isoindoles via Intramolecular Palladium‐Catalyzed CH Bond Activation
2010
Palladium-Catalyzed sp3 C—H Activation of Simple Alkyl Groups: Direct Preparation of Indoline Derivatives from N-Alkyl-2-bromoanilines
2008
Fine Feathers Make Fine Birds: The Heck Reaction in Modern Garb
1995
A Comprehensive History of Arynes in Natural Product Total Synthesis
2012 Standout
Palladium-Catalyzed C–H Homocoupling of Furans and Thiophenes Using Oxygen as the Oxidant
2014
Nickel-catalyzed cross coupling of non-activated alkyl halides: a mechanistic perspective
2011
Ru3(CO)12-Catalyzed Intermolecular Cyclocoupling of Ketones, Alkenes or Alkynes, and Carbon Monoxide. [2 + 2 + 1] Cycloaddition Strategy for the Synthesis of Functionalized γ-Butyrolactones
2000
Direct Arylation as a Synthetic Tool for the Synthesis of Thiophene-Based Organic Electronic Materials
2011
Palladium-Catalyzed Synthesis of 2-Substituted Benzothiazoles via a C−H Functionalization/Intramolecular C−S Bond Formation Process
2008
Nickel-Catalyzed Carbon–Carbon Bond-Forming Reactions of Unactivated Tertiary Alkyl Halides: Suzuki Arylations
2013
Controlled Regiodivergent C–H Bond Activation of Imidazo[1,5-a]pyridine via Synergistic Cooperation between Aluminum and Nickel
2014
Synthesis of Benzocyclobutenes by Palladium-Catalyzed C−H Activation of Methyl Groups: Method and Mechanistic Study
2008
Rhodium(III)-Catalyzed Regioselective C–H Alkenylation of Phenylphosphine Sulfides
2014
Cascade Palladium-Catalyzed Alkenyl Aminocarbonylation/ Intramolecular Aryl Amidation: An Annulative Synthesis of 2-Quinolones
2009
Catalytic Enantioselective Michael Reaction of 1,3‐Dicarbonyl Compounds via Formation of Chiral Palladium Enolate
2005
Rhodium-Catalyzed ortho-Benzoxylation of sp2 C−H Bond
2009
Hydroxyl-directed cyclopropanation of Z-allyl-silanes
1995
Chelation-assisted palladium-catalyzed acyloxylation of benzyl sp3 C–H bonds using PhI(OAc)2 as oxidant
2010
Development of Preformed Pd Catalysts for Cross-Coupling Reactions, Beyond the 2010 Nobel Prize
2012
Pd(OAc)2-Catalyzed Oxidative C−H/C−H Cross-Coupling of Electron-Deficient Polyfluoroarenes with Simple Arenes
2010
Ortho-selective Arylation of Arylazoles with Aryl Bromides Catalyzed by Ruthenium Complexes
2008
Rhodium-Catalyzed 1,4-Addition of Arylboronic Acids to α,β-Unsaturated Carbonyl Compounds: Large Accelerating Effects of Bases and Ligands
2003
Mild and efficient palladium-catalyzed intramolecular direct arylation reactions
2008
Copper-Catalyzed Direct Oxidative C–H Amination of Benzoxazoles with Formamides or Secondary Amines under Mild Conditions
2011
Catalysis for the Valorization of Exhaust Carbon: from CO2to Chemicals, Materials, and Fuels. Technological Use of CO2
2013 Standout
Allene formation by gold catalyzed cross-coupling of masked carbenes and vinylidenes
2007
Control of Product Selectivity by a Styrene Additive in Ruthenium-Catalyzed C−H Arylation
2010
All-Catalytic, Efficient, and Asymmetric Synthesis of α,ω-Diheterofunctional Reduced Polypropionates via “One-Pot” Zr-Catalyzed Asymmetric Carboalumination−Pd-Catalyzed Cross-Coupling Tandem Process
2005 StandoutNobel
Cu-Catalyzed Direct C6-Arylation of Indoles
2016
Modular Approach to Tricyclic Heterocycles through Copper Catalysis and Functionalization by Palladium‐Catalyzed C–H Arylation
2017
Catalytic Enantioselective Intramolecular Redox Reactions: Ring-Fused Tetrahydroquinolines
2009
γ-Methylidene-δ-valerolactones as a Coupling Partner for Cycloaddition: Palladium-Catalyzed [4 + 3] Cycloaddition with Nitrones
2007
Nickel-Catalyzed Reductive Cross-Coupling of Aryl Halides with Alkyl Halides
2010
Intermolecular Transition Metal-Catalyzed [4 + 2 + 2] Cycloaddition Reactions: A New Approach to the Construction of Eight-Membered Rings
2002
Rhodium(III)-Catalyzed Intermolecular Hydroarylation of Alkynes
2010
Bimetallic Oxidative Addition Involving Radical Intermediates in Nickel-Catalyzed Alkyl–Alkyl Kumada Coupling Reactions
2013
Rh(III)-Catalyzed Amide-Directed Cross-Dehydrogenative Heteroarylation of Pyridines
2013
Palladium-Catalyzed C−H Bond Functionalization with Arylsulfonyl Chlorides
2009
Rhodium-Catalyzed Oxidative ortho-Acylation of Benzamides with Aldehydes: Direct Functionalization of the sp2 C–H Bond
2011
Recent applications of the Suzuki–Miyaura cross-coupling reaction in organic synthesis
2002 Standout
Transition-Metal-Free Coupling Reactions
2014
Copper-Catalyzed Oxidative Cross-Coupling ofN,N-Dimethylanilines with Heteroarenes under Molecular Oxygen
2011
Iron-catalyzed arylation of benzoazoles with aromatic aldehydes using oxygen as oxidant
2012
Asymmetric IrI‐Catalysed Allylic Alkylation Of Monosubstituted Allylic Acetates With Phosphorus Amidites As Ligands
2003
Cu-Catalyzed Double S-Alkenylation of Potassium Sulfide: A Highly Efficient Method for the Synthesis of Various Thiophenes
2010
Solvias Josiphos Ligands: From Discovery to Technical Applications
2002
Synthesis of 1,2-Dihydropyridines Catalyzed by Well-Defined Low-Valent Cobalt Complexes: C–H Activation Made Simple
2015
Advances in Transition Metal (Pd,Ni,Fe)-Catalyzed Cross-Coupling Reactions Using Alkyl-organometallics as Reaction Partners
2011 Standout
Revealing a Second Transmetalation Step in the Negishi Coupling and Its Competition with Reductive Elimination: Improvement in the Interpretation of the Mechanism of Biaryl Syntheses
2009
Synthesis of 1-Aminoisoquinolines via Rh(III)-Catalyzed Oxidative Coupling
2011
Pd-catalyzed ortho-arylation of phenylacetamides, benzamides, and anilides with simple arenes using sodium persulfate
2010
Synthesis of Phosphoramidates: A Facile Approach Based on the C–N Bond Formation via Ir-Catalyzed Direct C–H Amidation
2014
Direct Pd-Catalyzed Arylation of 1,2,3-Triazoles
2007
Iron‐Catalyzed Cross Dehydrogenative Coupling (CDC) of Indoles and Benzylic CH Bonds
2015
Direct C–H Arylation of Heteroarenes with Copper Impregnated on Magnetite as a Reusable Catalyst: Evidence for CuO Nanoparticle Catalysis in Solution
2016
Cp2Ni-KOt-Bu-BEt3 (or PPh3) Catalyst System for Direct C−H Arylation of Benzene, Naphthalene, and Pyridine
2009
Cu(acac)2 catalyzed oxidative C–H bond amination of azoles with amines under base-free conditions
2012
Transition Metal-Catalyzed Direct Arylation of Substrates with Activated sp3-Hybridized C−H Bonds and Some of Their Synthetic Equivalents with Aryl Halides and Pseudohalides
2009
Organocatalysis in Cross-Coupling: DMEDA-Catalyzed Direct C−H Arylation of Unactivated Benzene
2010
Cobalt‐Catalyzed Cyclization of N‐Methoxy Benzamides with Alkynes using an Internal Oxidant through C−H/N−O Bond Activation
2016
Cobalt-Catalyzed C–H Arylations, Benzylations, and Alkylations with Organic Electrophiles and Beyond
2014
Gold and Platinum Catalysis of Enyne Cycloisomerization
2006
Copper-Catalyzed Enantioselective Conjugate Addition of Grignard Reagents to Acyclic Enones
2004 StandoutNobel
Rhodium-Catalyzed Arylation Using Arylboron Compounds: Efficient Coupling with Aryl Halides and Unexpected Multiple Arylation of Benzonitrile
2005
Cationic Ruthenium(II) Catalysts for Oxidative C–H/N–H Bond Functionalizations of Anilines with Removable Directing Group: Synthesis of Indoles in Water
2012
Highly Regioselective C2-Alkenylation of Indoles Using the N-Benzoyl Directing Group: An Efficient Ru-Catalyzed Coupling Reaction
2013
Nitrogen-Directed Ortho-Selective Homocoupling of Aromatic Compounds Catalyzed by Ruthenium Complexes
2008
Synthesis and Functionalization of Indoles Through Palladium-catalyzed Reactions
2005 Standout
Cobalt‐Catalyzed ortho‐C−H Functionalization/Alkyne Annulation of Benzylamine Derivatives: Access to Dihydroisoquinolines
2017
Synthesis of α‐Carbolines Starting from 2,3‐Dichloropyridines and Substituted Anilines
2008
Rhodium-Catalyzed Dehydrogenative Coupling of Phenylheteroarenes with Alkynes or Alkenes
2015
Efficient Cross‐Coupling Reactions of Nitrogen Nucleophiles with Aryl Halides in Water
2009
Transition metals in organic synthesis: Highlights for the year 2005
2007
On the role of anionic ligands in the site-selectivity of oxidative C–H functionalization reactions of arenes
2013
Chiral Phosphanodihydrooxazoles in Asymmetric Catalysis: Tungsten‐Catalyzed Allylic Substitution
1995
Synthesis of enantiomerically pure tributylstannylcyclopropanes through lipase-catalyzed reaction
1998
One-Pot Synthesis of 2-Substituted Indoles from 2-Aminobenzyl Phosphonium Salts. A Formal Total Synthesis of Arcyriacyanin A
2008
The Synthesis of Enantiopure ω‐Methanoprolines and ω‐Methanopipecolic Acids by a Novel Cyclopropanation Reaction: The “Flattering” of Proline
1997
Iridium-Catalyzed Direct C–H Sulfamidation of Aryl Nitrones with Sulfonyl Azides at Room Temperature
2015
Copper-Catalyzed Aerobic C(sp2)–H Functionalization for C–N Bond Formation: Synthesis of Pyrazoles and Indazoles
2013
Synthesis of Indolines by Copper-Mediated Intramolecular Aromatic C–H Amination
2015
Well-Defined Ruthenium(II) Carboxylate as Catalyst for Direct C–H/C–O Bond Arylations with Phenols in Water
2012
Palladium‐Catalyzed Monoselective Halogenation of CH Bonds: Efficient Access to Halogenated Arylpyrimidines using Calcium Halides
2010
Regio‐ and Stereoselective Syntheses with Organocopper Reagents
1997
Iron(II)-Catalyzed Intramolecular Olefin Aminofluorination
2014
Pd-Catalyzed Oxidative CH/CH Direct Coupling of Heterocyclic N-Oxides
2013
Cyclopropanation and epoxidation of 1,2-distannylalkenes and 1-silyl-2-stannylalkenes
1995
Construction of Pyridine Rings by Metal-Mediated [2 + 2 + 2] Cycloaddition
2003
The Regioselective Switch for Amino-NHC Mediated C–H Activation of Benzimidazole via Ni–Al Synergistic Catalysis
2012
Easy Access to 1‐Amino and 1‐Carbon Substituted Isoquinolines via Cobalt‐Catalyzed CH/NO Bond Activation
2016
Cross-Coupling of Non-activated Chloroalkanes with Aryl Grignard Reagents in the Presence of Iron/N-Heterocyclic Carbene Catalysts
2012
Computational rationalization of the selective C–H and C–F activations of fluoroaromatic imines and ketones by cobalt complexes
2014
Palladium-Catalyzed C−H Functionalization of Pyridine N-Oxides: Highly Selective Alkenylation and Direct Arylation with Unactivated Arenes
2008
C–H arylation and alkenylation of imidazoles by nickel catalysis: solvent-accelerated imidazole C–H activation
2015
Nickel-catalyzed decarboxylative arylation of azoles with perfluoro- and nitrobenzoates
2015
Palladium-Catalyzed Selective β-Arylation of Aliphatic Amides Using a Removable N,O-Bidentate Auxiliary
2015
One-pot synthesis of isoxazoles from enaminones: an application of Fe(II) as the catalyst for ring expansion of 2H-azirine intermediates
2013
Regioselective and Enantiospecific Rhodium-Catalyzed Allylic Amination withN-(Arylsulfonyl)anilines
2001
Iron‐Catalysed Reduction of Olefins using a Borohydride Reagent
2013
Silver-Promoted, Palladium-Catalyzed Direct Arylation of Cyclopropanes: Facile Access to Spiro 3,3′-Cyclopropyl Oxindoles
2013
Oxidative dimerization of azoles via copper(II)/silver(I)-catalyzed CH homocoupling
2009
Ruthenium-Catalyzed Oxidative Synthesis of 2-Pyridones through C–H/N–H Bond Functionalizations
2011
Water accelerated reduction system: Pinacolic coupling of aromatic carbonyl compounds and reductive dimerization cyclization of 1,1-dicyanoalkenes
1998
Remote C–H bond functionalization reveals the distance-dependent isotope effect
2008
Copper-Mediated Formally Dehydrative Biaryl Coupling of Azine N-Oxides and Oxazoles
2015
First Cobalt(I)-Catalyzed [6 + 2] Cycloadditions of Cycloheptatriene with Alkynes
2005
The first metal-catalyzed intramolecular [5+2] cycloadditions of vinylcyclopropanes and alkenes: Scope, stereochemistry, and asymmetric catalysis
1998
Versatile reactivity of Pd-catalysts: mechanistic features of the mono-N-protected amino acid ligand and cesium-halide base in Pd-catalyzed C–H bond functionalization
2014
Iron‐Catalyzed Direct C–H Arylation of Heterocycles and Quinones with Arylboronic Acids
2013
Pd(II)-Catalyzed para-Selective C–H Arylation of Monosubstituted Arenes
2011
Substituted Benzocarbocycles by Palladium‐Catalyzed Cascade Reactions Featuring a C(sp3)H Activation Step
2007
Copper(II)-catalyzed direct thiolation of C–H bonds in aromatic amides with aryl and aliphatic thiols
2014
Carboxylate-Assisted Transition-Metal-Catalyzed C−H Bond Functionalizations: Mechanism and Scope
2011 Standout
A Direct Access to 7-Aminoindoles via Iridium-Catalyzed Mild C–H Amidation of N-Pivaloylindoles with Organic Azides
2016
Expedient cobalt(ii )-catalyzed site-selective C7-arylation of indolines with arylboronic acids
2018
A facile synthesis of indolo[3,2,1-jk]carbazoles via palladium-catalyzed intramolecular cyclization
2012
FeCl3-Catalyzed Stereoselective Construction of Spirooxindole Tetrahydroquinolines via Tandem 1,5-Hydride Transfer/Ring Closure
2012
Pd(OAc)2 catalyzed C–H activation of 1,3,4-oxadiazoles and their direct oxidative coupling with benzothiazoles and aryl boronic acids using Cu(OAc)2 as an oxidant
2013
Recent Advances in the Transition-Metal-Catalyzed Regioselective Approaches to Polysubstituted Benzene Derivatives
2000
Ruthenium-Catalyzed Cycloaddition of 1,6-Diynes with Isothiocyanates and Carbon Disulfide: First Transition-Metal Catalyzed [2 + 2 + 2] Cocyclotrimerization Involving CS Double Bond
2001
Synthesis of Olefin‐Oxazoline Ligands (OlefOx) by Rhodium(III)‐Catalyzed Oxidative Olefination
2012
Palladium-Catalyzed Asymmetric [3 + 2] Trimethylenemethane Cycloaddition Reactions
2006
Synthesis of Biaryls through Aromatic CH Bond Activation: A Review of Recent Developments
2014
Shuttles and Muscles: Linear Molecular Machines Based on Transition Metals
2001 StandoutNobel
Palladium-Catalyzed Direct Arylation of Nitro-Substituted Aromatics with Aryl Halides
2008
Density Functional Theory Study of the Mechanisms of Iron-Catalyzed Cross-Coupling Reactions of Alkyl Grignard Reagents
2013
Enantioselective Catalytic Aziridinations and Asymmetric Nitrene Insertions into CH Bonds
2003
An Aromatic Glaser−Hay Reaction
2009
A Carbene-Stabilized Gold(I) Fluoride: Synthesis and Theory
2005
Iron-Catalyzed Direct Arylation through an Aryl Radical Transfer Pathway
2010
Palladium-Catalyzed Transformations of Alkyl C–H Bonds
2016 Standout
Regioselective Palladium-Catalyzed Arylation of 4-Chloropyrazoles
2010
Recent advances in the ruthenium-catalyzed hydroarylation of alkynes with aromatics: synthesis of trisubstituted alkenes
2015
Theoretical Studies on Intramolecular C–H Amination of Biaryl Azides Catalyzed by Four Different Late Transition Metals
2013
Axial Coordination of NHC Ligands on Dirhodium(II) Complexes: Generation of a New Family of Catalysts
2008
Controlling Site Selectivity in Pd-Catalyzed Oxidative Cross-Coupling Reactions
2011
Aryl Transfer between Pd(II) Centers or Pd(IV) Intermediates in Pd-Catalyzed Domino Reactions
2006
Palladium-Catalyzed Tandem Fluorination and Cyclization of Enynes
2011
The Atom Economy—A Search for Synthetic Efficiency
1991 StandoutScience
Ruthenium-catalyzed direct oxidative alkenylation of arenes through twofold C–H bond functionalization
2012
Palladium-Catalyzed Direct Synthesis of Carbazoles via One-Pot N-Arylation and Oxidative Biaryl Coupling: Synthesis and Mechanistic Study
2009
Oxidative C–H/C–H Coupling Reactions between Two (Hetero)arenes
2017
Dimerization of Cyclopropyl Ketones and Crossed Reactions of Cyclopropyl Ketones with Enones as an Entry to Five-Membered Rings
2006
N-Heterocyclic Carbenes in Late Transition Metal Catalysis
2009 Standout
Facile construction of pyrrolophenanthridone skeleton via a one-pot intramolecular Heck reaction and oxidation
2013
Waste-Free Synthesis of Condensed Heterocyclic Compounds by Rhodium-Catalyzed Oxidative Coupling of Substituted Arene or Heteroarene Carboxylic Acids with Alkynes
2009
Synthesis and characterization of a cyclic vinylpalladium(ii) complex: vinylpalladium species as the possible intermediate in the catalytic direct olefination reaction of enamide
2011
2-Furyl Phosphines as Ligands for Transition-Metal-Mediated Organic Synthesis
2001
Using computational methods to explore improvements to Knölker's iron catalyst
2014
Transition Metal‐Mediated Direct CH Arylation of Heteroarenes Involving Aryl Radicals
2014
Synthesis of Azapolycyclic Systems via the Intramolecular [4 + 2] Cycloaddition Chemistry of 2-(Alkylthio)-5-amidofurans
2002
Carbonylative [5 + 1] Cycloaddition of Cyclopropyl Imines Catalyzed by Ruthenium Carbonyl Complex
2000
Metal-Catalyzed Reactions of Organoboronic Acids and Esters
2008
Ortho Alkylation of Aromatic Ketimine with Functionalized Alkene by Rh(I) Catalyst
2004
The Complementary Competitors: Palladium and Copper in C–N Cross-Coupling Reactions
2012
Chelation-Assisted Copper-Mediated Direct Acetylamination of 2-Arylpyridine C–H Bonds with Cyanate Salts
2016
Copper-catalyzed enantioselective conjugate addition of Grignard reagents to acyclic enones using monodentate phosphoramidite ligands
2008 StandoutNobel
Enantioselective Construction of Spirocyclic Oxindolic Cyclopentanes by Palladium-Catalyzed Trimethylenemethane-[3+2]-Cycloaddition
2007
Synthesis of 6-oxacyclopropa[a]indene derivatives starting from Baylis–Hillman adducts via Pd-mediated C(sp3)–H activation
2008
Copper-Mediated Dehydrogenative Biaryl Coupling of Naphthylamines and 1,3-Azoles
2013
Palladium-Catalyzed Reactions of Allenes
2000
Intramolecular Pd(II)-Catalyzed Oxidative Biaryl Synthesis Under Air: Reaction Development and Scope
2008
Synthesis of Quinoline-Based NNN-Pincer Nickel(II) Complexes: A Robust and Improved Catalyst System for C–H Bond Alkylation of Azoles with Alkyl Halides
2016
A Convergent Synthesis of Functionalized Alkenyl Halides through Cobalt(III)‐Catalyzed Three‐Component C−H Bond Addition
2017
Olefin Metathesis and Beyond
2000 Standout
Rhodium-Catalyzed Hydroarylation of Alkynes with Arylboronic Acids: 1,4-Shift of Rhodium from 2-Aryl-1-alkenylrhodium to 2-Alkenylarylrhodium Intermediate
2001
Element−Element Additions to Unsaturated Carbon−Carbon Bonds Catalyzed by Transition Metal Complexes
2006
Mechanistic Study of Chemoselectivity in Ni-Catalyzed Coupling Reactions between Azoles and Aryl Carboxylates
2014
Regio- and Enantioselective Intermolecular Hydroacylation: Substrate-Directed Addition of Salicylaldehydes to Homoallylic Sulfides
2010
Advances in the Chemistry of Tetrahydroquinolines
2011 Standout
Retention or Inversion in Stereospecific Nickel-Catalyzed Cross-Coupling of Benzylic Carbamates with Arylboronic Esters: Control of Absolute Stereochemistry with an Achiral Catalyst
2013
Iron-Catalyzed Arylation of Heterocycles via Directed C–H Bond Activation
2014
Titanocene(III)-Catalyzed Formation of Indolines and Azaindolines
2008
Palladium-catalyzed cascade cyclization-coupling reactions of 2-bromo-1,6-enynes with organoboronic acids
2003
Development of Halogenase Enzymes for Use in Synthesis
2017
Synthesis of axially chiral biaryl compounds by asymmetric catalytic reactions with transition metals
2015
Ligand and solvent-free iron catalyzed oxidative alkynylation of azoles with terminal alkynes
2011
Regioselective Introduction of Heteroatoms at the C-8 Position of Quinoline N-Oxides: Remote C–H Activation Using N-Oxide as a Stepping Stone
2014
Domino Palladium-Catalyzed Heck-Intermolecular Direct Arylation Reactions
2009
Cobalt-Catalyzed Addition of Arylzinc Reagents to Norbornene Derivatives through 1,4-Cobalt Migration
2014
Copper-Catalyzed Domino Annulation Approaches to the Synthesis of Benzoxazoles under Microwave-Accelerated and Conventional Thermal Conditions
2008
Rapid access to diverse α-carbolines through sequential transition metal catalyzed amination and direct C–H arylation
2014
Iron or boron-catalyzed C–H arylthiation of substituted phenols at room temperature
2014
Rhodium-catalyzed regioselective opening of vinyl epoxides with Et3N·3HF reagent – formation of allylic fluorohydrins
2013
“Formal” Ruthenium-Catalyzed [4+2+2] Cycloaddition of 1,6-Diynes to 1,3-Dienes: Formation of Cyclooctatrienes vs Vinylcyclohexadienes
2003
Mechanistic understanding of Rh-catalyzed N-sulfonylaldimine insertion into aryl C–H bonds
2012
Rhodium-Catalyzed Synthesis of Isoquinolines and Indenes from Benzylidenehydrazones and Internal Alkynes
2014
Halohydroxylation of alkylidenecyclopropanes using N-halosuccinimide (NXS) as the halogen source: an efficient synthesis of halocyclopropylmethanol and 3-halobut-3-en-1-ol derivatives
2009
Synthesis of 2,6-dimethyl-9-aryl-9-phosphabicyclo[3.3.1]nonanes: their application to asymmetric synthesis of chiral tetrahydroquinolines and relatives
2007
Copper-mediated C–H(sp2)/C–H(sp3) coupling of benzoic acid derivatives with ethyl cyanoacetate: an expedient route to an isoquinolinone scaffold
2014
Catalytic Dehydrogenative Cross-Coupling: Forming Carbon−Carbon Bonds by Oxidizing Two Carbon−Hydrogen Bonds
2011 Standout
Use of π-allylpalladium as a nucleophile via an alkyl-allyl exchange reaction with alkylzinc
1993
Cu-Catalyzed Carbon-Heteroatom Coupling Reactions under Mild Conditions Promoted by Resin-Bound Organic Ionic Bases
2010
Modified palladium-catalyzed regioselective ortho-arylation of sp2 C–H bond substrates with a low catalyst loading
2008
Palladium catalyzed tandem alkenyl- and aryl-C–N bond formation: a cascade N-annulation route to 4-, 5-, 6- and 7-chloroindoles
2010
C–H Bond Arylations and Benzylations on Oxazol(in)es with a Palladium Catalyst of a Secondary Phosphine Oxide
2011
Organocuprate Conjugate Addition: The Square-Planar “CuIII” Intermediate
2007
Mechanism and Selectivity in Nickel-Catalyzed Cross-Electrophile Coupling of Aryl Halides with Alkyl Halides
2013
C−H Bonds as Ubiquitous Functionality: A General Approach to Complex Arylated Pyrazoles via Sequential Regioselective C-Arylation and N-Alkylation Enabled by SEM-Group Transposition
2009
Regio- and Enantioselective Allylic Alkylation of an Unsymmetrical Substrate: A Working Model
1999
Copper-Catalyzed Synthesis of Purine-Fused Polycyclics
2012
Mechanistic insight into Cu/Ag-cocatalyzed C–H activation of arenes with oxygen as the terminal oxidant
2016
Ruthenium-Catalyzed Meta Sulfonation of 2-Phenylpyridines
2011
Rhodium- and iridium-catalyzed oxidative coupling of benzoic acids with alkynes and alkenes
2008
Biomass-derived solvents as effective media for cross-coupling reactions and C–H functionalization processes
2017
Mechanistic Investigations of Palladium-Catalyzed Allylic Fluorination
2014
Stereoselective Cyclopropanation Reactions
2003 Standout
Phosphonium Coupling in the Direct Bond Formations of Tautomerizable Heterocycles via C–OH Bond Activation
2008
Iron-catalyzed Cross-Coupling of Electron-Deficient Heterocycles and Quinone with Organoboron Species via Innate C–H Functionalization: Application in Total Synthesis of Pyrazine Alkaloid Botryllazine A
2013
The stereoselective cyclopropanation of chiral allylic alcohols using a chiral dioxaborolane ligand: A new route to anti-cyclopropylmethanol derivatives
1999
Allylic geminal diacetates. Unusual carbonyl substitutes via metal catalyzed reactions
1985
Copper‐catalyzed/mediated aromatic CH bond functionalization
2010
High‐Valent‐Cobalt‐Catalyzed C−H Functionalization Based on Concerted Metalation–Deprotonation and Single‐Electron‐Transfer Mechanisms
2016
Palladium(II)-Catalyzed Direct Alkenylation and Arylation of Arenes: Removable 2-Pyridylsulfinyl Group Assisted C–H Bond Activation
2011
Substituent-Directed Regioselective Azidation: Copper-Catalyzed C–H Azidation and Iodine-Catalyzed Dearomatizative Azidation of Indole
2017
Palladium-Catalyzed Benzylation of Heterocyclic Aromatic Compounds
2009
RuCl3-Catalyzed Alkenylation of Aromatic C−H Bonds with Terminal Alkynes
2008
Ruthenium(II) Acetate Catalyst for Direct Functionalisation of sp2‐CH Bonds with Aryl Chlorides and Access to Tris‐ Heterocyclic Molecules
2009
Ni-Catalyzed Sonogashira Coupling of Nonactivated Alkyl Halides: Orthogonal Functionalization of Alkyl Iodides, Bromides, and Chlorides
2009
Cu(II) Catalyzed Imine C–H Functionalization Leading to Synthesis of 2,5-Substituted 1,3,4-Oxadiazoles
2011
Catalytic Methods for Aromatic C–H Amination: An Ideal Strategy for Nitrogen-Based Functional Molecules
2015
Investigation of the Mechanism of C(sp3)−H Bond Cleavage in Pd(0)-Catalyzed Intramolecular Alkane Arylation Adjacent to Amides and Sulfonamides
2010
Asymmetric Synthesis of Diarylmethyl Amines by Rhodium‐Catalyzed Asymmetric Addition of Aryl Titanium Reagents to Imines
2004
Iron‐Catalyzed Intramolecular C(sp2)−H Amination
2015
Synthesis of Silicon Substituted Cyclopropylmethyl Alcohols in Optically Active Form via Asymmetric Simmons-Smith Reaction of γ-Silicon Substituted Allylic Alcohols
1993
Palladium-Catalyzed [4 + 3] Intramolecular Cycloaddition of Alkylidenecyclopropanes and Dienes
2007
Catalytic Cycle of Rhodium-Catalyzed Asymmetric 1,4-Addition of Organoboronic Acids. Arylrhodium, Oxa-π-allylrhodium, and Hydroxorhodium Intermediates
2002
Direct coupling of arenes and iodoarenes catalyzed by a rhodium complex with a strongly π-accepting phosphite ligand
2008 Nobel
Tandem Isomerization and C–H Activation: Regioselective Hydroheteroarylation of Allylarenes
2013
Copper-catalyzed direct C–H arylation of pyridine N-oxides with arylboronic esters: one-pot synthesis of 2-arylpyridines
2014
Non-conventional methodologies for transition-metal catalysed carbon–carbon coupling: a critical overview. Part 2: The Suzuki reaction
2007
Optimisation of Permanganate Oxidation and Suzuki−Miyaura Coupling Steps in the Synthesis of a Nav1.8 Sodium Channel Modulator
2009
Isothiocyanate-Directed Ortho-Selective Halogenation of Arenes via C–H Functionalization
2017
Catalytic Sequential Reactions Involving Palladacycle-Directed Aryl Coupling Steps
2008
Carbon−Hydrogen Bond Functionalization Approach for the Synthesis of Fluorenones and ortho-Arylated Benzonitriles
2008
Evaluation of Electron‐Deficient Phosphine Ligands for Direct Arylation of Heterocycles
2010
Improved Protocol for Indoline Synthesis via Palladium-Catalyzed Intramolecular C(sp2)–H Amination
2012
A General Rhodium‐Catalyzed Cyanation of Aryl and Alkenyl Boronic Acids
2010
Metal-Assisted Cycloaddition Reactions in Organotransition Metal Chemistry
1997
Cobalt-Catalyzed Addition of Azoles to Alkynes
2010
Copper-Catalyzed Synthesis of Phenanthridine Derivatives under an Oxygen Atmosphere Starting from Biaryl-2-carbonitriles and Grignard Reagents
2010
Ester‐Directed Selective Olefination of Acrylates by Rhodium Catalysis
2014
Oxidative Coupling of Arylboronic Acids with Arenes via Rh-Catalyzed Direct C−H Arylation
2007
Manganese-Catalyzed C–H Activation
2016
Palladium(II)‐katalysierte C‐H‐Aktivierung/C‐C‐Kreuzkupplung: Vielseitigkeit und Anwendbarkeit
2009
Copper-Catalyzed Amidation of 2-Phenylpyridine with Oxygen as the Terminal Oxidant
2011
Integrated Cross-Coupling Strategy for an α-Carboline-Based Aurora B Kinase Inhibitor
2015
Highly Regioselective Palladium-Catalyzed Direct Arylation of Oxazole at C-2 or C-5 with Aryl Bromides, Chlorides, and Triflates
2010
Iron-Catalyzed Cross-Coupling Reactions between Arylzinc Reagents and Alkyl Halides Bearing β-Fluorines
2011
Copper-catalyzed direct thiolation of benzoxazole with diaryl disulfides and aryl thiols
2009
Regioselective Cross‐Dehydrogenative Coupling of Chromones and Non‐Activated Arenes
2012
The mechanism of nucleophilic addition to η3-allylpalladium complexes: the influence of ligands on rates and regiochemistry
1987
Ruthenium(II)-Catalyzed C–H Arylation of Azoarenes by Carboxylate Assistance
2015
Synthesis of 2,5-diaryloxazoles through van Leusen reaction and copper-mediated direct arylation
2009
A simple, base-free preparation of S-aryl thioacetates as surrogates for aryl thiols
2010
Anti-Markovnikov hydroarylation of styrenes catalyzed by an in situ generated ruthenium complex
2008
Transition-Metal-Catalyzed C−S, C−Se, and C−Te Bond Formation via Cross-Coupling and Atom-Economic Addition Reactions
2011 Standout
Copper-Catalyzed Oxidative Amination of Benzoxazoles via C−H and C−N Bond Activation: A New Strategy for Using Tertiary Amines as Nitrogen Group Sources
2010
Palladium-Catalyzed Addition of Alcohol Pronucleophiles to Alkylidenecyclopropanes
2000
Carbon−Carbon Bond Formation Involving Reactions of Alkynes with Group 9 Metals (Ir, Rh, Co): Preparation of Conjugated Olefins
2002
Advances in Catalytic Enantioselective Fluorination, Mono-, Di-, and Trifluoromethylation, and Trifluoromethylthiolation Reactions
2014
Palladium catalyzed asymmetric allylic alkylation using chelating N-heterocyclic carbene–amino ligands
2007
Katalytische asymmetrische Tandemumwandlungen mit einer konjugierten Addition als einleitendem Schritt
2005
Palladium‐Catalyzed C3 or C4 Direct Arylation of Heteroaromatic Compounds with Aryl Halides by CH Bond Activation
2009
Nickel N-Heterocyclic Carbene Catalyst for Cross-Coupling of Neopentyl Arenesulfonates with Methyl and Primary Alkyl Grignard Reagents
2009
Metal-Mediated Synthesis of Medium-Sized Rings
2000
Efficient synthesis of 3-substituted 2,3-dihydroquinolin-4-ones using a one-pot sequential multi-catalytic process: Pd-catalyzed allylic amination–thiazolium salt-catalyzed Stetter reaction cascade
2006
Synthesis of biaryls using aryne intermediates
2016
Transition metal-catalyzed C–H bond functionalizations by the use of diverse directing groups
2015
Recent advances in positional-selective alkenylations: removable guidance for twofold C–H activation
2017
Highly Enantioselective Iridium-Catalyzed Hydrogenation of 2-Benzylquinolines and 2-Functionalized and 2,3-Disubstituted Quinolines
2009
Transition-Metal-Catalyzed C–H Alkylation Using Alkenes
2017
Heterocycle Formation via Palladium-Catalyzed Intramolecular Oxidative C−H Bond Functionalization: An Efficient Strategy for the Synthesis of 2-Aminobenzothiazoles
2009
Carboxylate-Assisted Ruthenium-Catalyzed Alkyne Annulations by C–H/Het–H Bond Functionalizations
2013 Standout
N‐Heterocyclic Carbene Ligands and Iron: An Effective Association for Catalysis
2013
A Straightforward Procedure for the [2+2+2] Cycloaddition of Enediynes
2008
Iron(II)‐Catalyzed Direct Cyanation of Arenes with Aryl(cyano)iodonium Triflates
2014
Benzofuran synthesis via copper-mediated oxidative annulation of phenols and unactivated internal alkynes
2013
Cu(II)-mediated oxidative dimerization of 2-phenylpyridine derivatives
2008
Synthesis and Structural Characterization of Nickel(II) Complexes Supported by Pyridine-Functionalized N-Heterocyclic Carbene Ligands and Their Catalytic Acitivities for Suzuki Coupling
2007
Pd(ii )-Catalyzed arylation of unactivated methylene C(sp3)–H bonds with aryl halides using a removable auxiliary
2014
Functionalized Phenanthridine and Dibenzopyranone Derivatives through Benzyne Cyclization – Application to the Total Syntheses of Trisphaeridine and N‐Methylcrinasiadine
2006
Palladium-Catalyzed Oxidative Ethoxycarbonylation of Aromatic C−H Bond with Diethyl Azodicarboxylate
2008
Copper-Catalyzed Etherification of Arene C–H Bonds
2013
Nickel‐Catalyzed C−H Heteroarylation of Chiral Oxazolines
2017
Selectivity in Nickel-Catalyzed Rearrangements of Cyclopropylen-ynes
2005
Transition Metal‐Catalysed, Direct and Site‐Selective N1‐, C2‐ or C3‐Arylation of the Indole Nucleus: 20 Years of Improvements
2009
Mechanistic Study of Acetate-Assisted C−H Activation of 2-Substituted Pyridines with [MCl2Cp*]2(M = Rh, Ir) and [RuCl2(p-cymene)]2
2008
[RuCl3(H2O)n]-catalyzed direct arylations
2008
Iron-Catalyzed Cross-Coupling of Alkyl Sulfonates with Arylzinc Reagents
2009
Recent Developments in C–H Activation for Materials Science in the Center for Selective C–H Activation
2018
Palladium-catalyzed hydroselenation of allenes with benzeneselenol
1998
Nickel-Catalyzed Biaryl Coupling of Heteroarenes and Aryl Halides/Triflates
2009
Palladium‐Catalyzed Highly Regioselective Arylation of Allylamines with Thiophenes and Furans
2012
1,1-Dibromo-1-alkenes as Valuable Partners in the Copper-Catalyzed Direct Alkynylation of Azoles
2010
C–H Bond Functionalization of Arylpyrimidines Catalyzed by an in situ Generated Ruthenium(II) Carboxylate System and the Construction of Tris(heteroaryl)‐Substituted Benzenes
2011
N-Acyloxyphthalimides as Nitrogen Radical Precursors in the Visible Light Photocatalyzed Room Temperature C–H Amination of Arenes and Heteroarenes
2014
Asymmetric Palladium-Catalyzed Directed Intermolecular Fluoroarylation of Styrenes
2014
Natural Product Synthesis by C−H Activation
2018
Synthesis of Fused 1-Aminoindole Polycycles by a Sequence of Palladium-Catalyzed N–H and C(sp2)–H Arylations
2014
Directed C–H Alkenylation of Aryl Imines with Alkenyl Phosphates Promoted by a Cobalt–N‐Heterocyclic Carbene Catalyst
2017
Rhodium-Catalyzed C3-Selective Alkenylation of Substituted Thiophene-2-carboxylic Acids and Related Compounds
2013
Ruthenium-Catalyzed Reactions for Organic Synthesis
1998
RECENT APPLICATIONS OF ARYNE CHEMISTRY TO ORGANIC SYNTHESIS. A REVIEW
2008
Palladium-Catalyzed Direct Alkynylation of C−H Bonds in Benzenes
2009
An efficient catalytic system for the hydrogenation of quinolines
2007
Cobalt-Catalyzed, Room-Temperature Addition of Aromatic Imines to Alkynes via Directed C–H Bond Activation
2011
Palladium-catalyzed cycloisomerizations of enynes and related reactions
1990
Aqueous Catalytic Polymerization of Olefins
2002
Density functional computations of the cyclopropanation of ethene catalyzed by iron (II) carbene complexes Cp(CO)(L)FeCHR, L = CO, PMe3, R = Me, OMe, ph, CO2Me
2007
Highly Regio- and Stereoselective Ruthenium(II)-Catalyzed Direct ortho-Alkenylation of Aromatic and Heteroaromatic Aldehydes with Activated Alkenes under Open Atmosphere
2012
Nickel-Catalyzed Direct Alkynylation of Azoles with Alkynyl Bromides
2009
Transition-Metal-Catalyzed Cycloisomerizations of α,ω-Dienes
2012
Regioselective Ruthenium-Catalyzed Direct Benzylations of Arenes through C−H Bond Cleavages
2009
User‐Friendly [(Diglyme)NiBr2]‐Catalyzed Direct Alkylations of Heteroarenes with Unactivated Alkyl Halides through CH Bond Cleavages
2011
Ruthenium-Catalyzed Heck-Type Olefination and Suzuki Coupling Reactions: Studies on the Nature of Catalytic Species
2003
Total Synthesis of Formamicin
2004
Palladium-Catalyzed Cyclization Reactions of 2-Vinylthiiranes with Heterocumulenes. Regioselective and Enantioselective Formation of Thiazolidine, Oxathiolane, and Dithiolane Derivatives
2001
Cobalt‐Catalyzed Oxidative Annulation of Nitrogen‐Containing Arenes with Alkynes: An Atom‐Economical Route to Heterocyclic Quaternary Ammonium Salts
2016
Experimental and Theoretical Studies on Rhodium-Catalyzed Coupling of Benzamides with 2,2-Difluorovinyl Tosylate: Diverse Synthesis of Fluorinated Heterocycles
2017
gem-Disubstituent Effect: Theoretical Basis and Synthetic Applications
2005
Copper-Catalyzed Direct Amination of Electron-Deficient Arenes with Hydroxylamines
2011
Improved Turnover Numbers in Palladium‐Catalyzed Bisdiene Cyclization‐Trapping using N‐Heterocyclic Carbene Ligands
2005
Iron-catalyzed allylic alkylation
1985
ortho‐Olefination of Arylaldehyde O‐Methyloximes through Palladium‐Catalyzed C–H Activation
2012
Palladium-Catalyzed Aerobic Dehydrogenative Cross-Coupling of Polyfluoroarenes with Thiophenes: Facile Access to Polyfluoroarene–Thiophene Structure
2011
Synthesis, Characterization and Catalytic Activity of New N‐Heterocyclic Bis(carbene)ruthenium Complexes
2009
Copper(II)-Catalyzed Dehydrogenative Cross-Coupling between Two Azoles
2012
Mechanisms and Origins of Switchable Chemoselectivity of Ni-Catalyzed C(aryl)–O and C(acyl)–O Activation of Aryl Esters with Phosphine Ligands
2014
Iron-catalyzed oxidative homo-coupling of indoles via C–H cleavage
2010
Molecular Engineering of Mechanochromic Materials by Programmed C–H Arylation: Making a Counterpoint in the Chromism Trend
2016
Auto‐Tandem Catalysis: Synthesis of Acridines by Pd‐Catalyzed C=C Bond Formation and C(sp2)–N Cross‐Coupling
2012
Rhodium N-Heterocyclic Carbene-Catalyzed [4 + 2] and [5 + 2] Cycloaddition Reactions
2005
Ruthenium(II)-Catalyzed C–H Bond Activation and Functionalization
2012 Standout
Nickel‐Catalyzed Decarboxylative Arylation of Heteroarenes through sp2 C–H Functionalization
2014
Pd-Catalyzed Intermolecular ortho-C−H Amidation of Anilides by N-Nosyloxycarbamate
2010
Palladium(ii)-catalyzed cross-coupling of simple alkenes with acrylates: a direct approach to 1,3-dienes through C–H activation
2013
A General Method for Copper-Catalyzed Arene Cross-Dimerization
2011
Asymmetric Transformations under Iridium/Chiral Diene Catalysis
2016
Copper-Catalyzed Cross-Dehydrogenative C–N Bond Formation of Azines with Azoles: Overcoming the Limitation of Oxidizing N–O Activation Strategy
2015
Insights into Directing Group Ability in Palladium-Catalyzed C−H Bond Functionalization
2008
Rhodium-Catalyzed Asymmetric 1,4-Addition and Its Related Asymmetric Reactions
2003
Catalytic Intermolecular Allylic C—H Alkylation
2008
Ruthenium-Catalyzed C–H/N–O Bond Functionalization: Green Isoquinolone Syntheses in Water
2011
Domino N−H/C−H Bond Activation: Copper-Catalyzed Synthesis of Nitrogen-Bridgehead Heterocycles Using Azoles and 1,4-Dihalo-1,3-dienes
2010
Cross Dehydrogenative Coupling (CDC) Reactions of N,N‐Disubstituted Formamides, Benzaldehydes and Cycloalkanes
2016
Recyclable Copper Catalyst for meta‐Selective CH Bond Arylation
2011
Direct Alkynylation of 3H-Imidazo[4,5-b]pyridines Using gem-Dibromoalkenes as Alkynes Source
2016
Copper mediated decarboxylative direct C–H arylation of heteroarenes with benzoic acids
2015
Catalytic Asymmetric Conjugate Addition and Allylic Alkylation with Grignard Reagents
2008 StandoutNobel
Triple Ring Closing Metathesis Reaction: Synthesis of Adjacent Cyclic Ethers
2001
Rhodium(III)-Catalyzed Oxidative Alkenylation of 1,3-Dithiane-Protected Arenecarbaldehydes via Regioselective C–H Bond Cleavage
2015
Ruthenium Complex‐Catalysed Heck Reactions of Areneboronic Acids; Mechanism, Synthesis and Halide Tolerance
2005
Palladium-catalysed regioselective aroylation and acetoxylation of 3,5-diarylisoxazole via ortho C–H functionalisations
2013
Ru(II)-Catalyzed Amidation of 2-Arylpyridines with Isocyanates via C–H Activation
2012
Copper(II) Acetate/Oxygen‐Mediated Nucleophilic Addition and Intramolecular CH Activation/CN or CC Bond Formation: One‐Pot Synthesis of Benzimidazoles or Quinazolines
2010
Rhodium-Catalyzed Direct Oxidative Carbonylation of Aromatic C−H Bond with CO and Alcohols
2008
Reinvestigation of the chemoselective cyclopropanation of allylic alcohols, allylic ethers and alkenes: a comparison between various reagents and protocols
2001
Ruthenium-Catalyzed Carbonylation at Ortho C−H Bonds in Aromatic Amides Leading to Phthalimides: C−H Bond Activation Utilizing a Bidentate System
2009
Cobalt-catalyzed redox-neutral synthesis of isoquinolines: C–H activation assisted by an oxidizing N–S bond
2016
Mechanistic Aspects of Pincer Nickel(II)-Catalyzed C–H Bond Alkylation of Azoles with Alkyl Halides
2018
A Highly Efficient Ruthenium(II) Catalyst with (1,2-Diarylvinyl)phosphine Ligands for Direct Ortho Arylation of 2-Arylpyridine with Aryl Chlorides
2010
Organic Reactions in Aqueous Media with a Focus on Carbon−Carbon Bond Formations: A Decade Update
2005 Standout
Recent developments in enantioselective scandium–catalyzed transformations
2016
Copper-Catalyzed Dehydrogenative Cross-Coupling of Benzothiazoles with Thiazoles and Polyfluoroarene
2012
Palladium-Catalyzed Arylation and Alkylation of 3,5-Diphenylisoxazole with Boronic Acids via C−H Activation
2008
Diastereotopic Differentiation on Phosphorus Templates via the Ring-Closing Metathesis Reaction
2000
Oxidative C–H/C–H Coupling of Azine and Indole/Pyrrole Nuclei: Palladium Catalysis and Synthesis of Eudistomin U
2011
Palladium- and Copper-Catalyzed Arylation of Carbon−Hydrogen Bonds
2009 Standout
N-Boc-l -Valine-Connected Amidomonophosphane Rhodium(I) Catalyst for Asymmetric Arylation of N-Tosylarylimines with Arylboroxines
2004
C−H Activation of Phenyl Imines and 2-Phenylpyridines with [Cp*MCl2]2 (M = Ir, Rh): Regioselectivity, Kinetics, and Mechanism
2009
Oxidative Nickel–Air Catalysis in CH Arylation: Direct Cross‐Coupling of Azoles with Arylboronic Acids using Air as Sole Oxidant
2010
Cyclopropanation of Protected Chiral, Acyclic Allylic Alcohols: Expedient Access to the anti-Cyclopropylcarbinol Derivatives
2002
A General Method for Copper-Catalyzed Arylation of Arene C−H Bonds
2008
“On Water” Direct and Site‐Selective Pd‐Catalysed CH Arylation of (NH)‐Indoles
2010
Novel catalytic reactions involving π-allylpalladium and -nickel as the key intermediates: umpolung and β-decarbopalladation of π-allylpalladium and nickel-catalyzed homoallylation of carbonyl compounds with 1,3-dienes
1999
High Efficiency and Enantioselectivity in the Rh-Catalyzed Conjugate Addition of Arylboronic Acids Using Monodentate Phosphoramidites
2003 StandoutNobel
Synthesis of Stilbene and Distyrylbenzene Derivatives through Rhodium-Catalyzed Ortho-Olefination and Decarboxylation of Benzoic Acids
2010
New studies of Rh-catalyzed addition of boronic acids under basic conditions in aqueous medium
2002
Palladium(II)-Catalyzed Oxidative C−H/C−H Cross-Coupling of Heteroarenes
2010
Selective Synthesis of 3-Aryl Quinolin-2(1H)-ones and 3-(1-Arylmethylene)oxindoles Involving a 2-Fold Arene C−H Activation Process
2009
A novel method for the synthesis of vicinal disulfonamides promoted by metallic samarium in aqueous media
2002
Rhodium-Catalyzed Silylcarbocyclization (SiCaC) and Carbonylative Silylcarbocyclization (CO−SiCaC) Reactions of Enynes
2002
Ortho Arylation of Acetanilides via Pd(II)-Catalyzed C−H Functionalization
2007
Copper-Catalyzed “Click” Reaction/Direct Arylation Sequence: Modular Syntheses of 1,2,3-Triazoles
2008
Synthesis of Triarylpyridines in Thiopeptide Antibiotics by Using a C−H Arylation/Ring‐Transformation Strategy
2016
Emergence of Palladium(IV) Chemistry in Synthesis and Catalysis
2010
Large-Scale Applications of Transition Metal-Catalyzed Couplings for the Synthesis of Pharmaceuticals
2011 Standout
Ruthenium-Catalyzed Hydroarylations of Methylenecyclopropanes: Mild C−H Bond Functionalizations with Conservation of Cyclopropane Rings
2008
Regioselective Functionalization of the Imidazole Ring via Transition Metal‐Catalyzed CN and CC Bond Forming Reactions
2010
Functionalization of the Benzylic C–H Bonds in Azaarenes by Cobalt‐Catalyzed 1,4‐Addition to Enones
2014
Carbofluorination via a palladium-catalyzed cascade reaction
2013
Key Mechanistic Features of Ni-Catalyzed C–H/C–O Biaryl Coupling of Azoles and Naphthalen-2-yl Pivalates
2014
An Enyne Cycloisomerization Approach to the Triple Reuptake Inhibitor GSK1360707F
2010
Gold-Catalyzed Tandem Reactions of Methylenecyclopropanes and Vinylidenecyclopropanes
2013
Ir and Rh complex-catalyzed intramolecular alkyne–alkyne couplings with carbon monoxide and isocyanides
2002
Copper‐Mediated C–H Activation of 1,3,4‐Oxadiazoles with 1,1‐Dibromo‐1‐alkenes Using PEG‐400 as a Solvent Medium: Distinct Approach for the Alkynylation of 1,3,4‐Oxadiazoles
2011
Rhodium-catalyzed and Coordination-assisted Regioselective Alkenylation of Aromatic C–H Bonds with Terminal Silylacetylenes
2008
A New Strategy for the Stereoselective Synthesis of 1,2,3-Trisubstituted Cyclopropanes
2000
Ni-Catalyzed Carboxylation of C(sp2)– and C(sp3)–O Bonds with CO2
2013
Iron-catalysed reduction of carbonyls and olefins
2011
Copper‐Catalysed, Enantioselective Desymmetrisation of meso Cyclic Allylic Bis(diethyl phosphates) with Organozinc Reagents
2005
Intermolecular Dehydrogenative Heck Reactions
2011
Pd(ii )-catalyzed β-C–H arylation of O-methyl ketoximes with iodoarenes
2016
Copper-Mediated C−H Bond Arylation of Arenes with Arylboronic Acids
2008
Iridium(I)-Catalyzed Regio- and Enantioselective Decarboxylative Allylic Amidation of Substituted Allyl Benzyl Imidodicarbonates
2007
Ruthenium-Catalyzed Ortho-Alkenylation of Aromatic Ketones with Alkenes by C–H Bond Activation
2011
Direct Palladium-Catalyzed C-3 Arylation of Free (NH)-Indoles with Aryl Bromides under Ligandless Conditions
2008
Epoxidation and cyclopropanation of 2-silyl-3-alkenols. A study of 1,2-asymmetric induction
1996
A new palladium catalyst for intramolecular carbametalations of enynes
1989
Copper‐Catalyzed Aerobic Oxidative Synthesis of 5‐Substituted Imidazo/Benzimidazoquinazolinones through Intramolecular CH Amination
2012
The Fe(PDP)-catalyzed aliphatic C–H oxidation: a slow addition protocol
2008
Synthesis of Biaryls via Palladium‐Catalyzed [2+2+2] Cocyclization of Arynes and Diynes: Application to the Synthesis of Arylnaphthalene Lignans
2007
Mechanistic Insight into Direct Arylations with Ruthenium(II) Carboxylate Catalysts
2010
Unsymmetrical Diaryl Sulfones and Aryl Vinyl Sulfones through Palladium-Catalyzed Coupling of Aryl and Vinyl Halides or Triflates with Sulfinic Acid Salts
2004
Iron-catalysed, hydride-mediated reductive cross-coupling of vinyl halides and Grignard reagents
2011
Rh(I)-catalyzed intramolecular hetero-[4+2] cycloaddition of ω-alkynyl-vinyl oximes
2007
Air‐Stable Bifunctional HASPO Preligands for Metal‐Catalyzed Cross‐Couplings and Direct C–H Bond Arylations
2010
Phenanthrene Synthesis via Chromium-Catalyzed Annulation of 2-Biaryl Grignard Reagents and Alkynes
2017
Ruthenium-catalyzed direct arylations with aryl chlorides
2016
Impact of Natural Products on Developing New Anti-Cancer Agents
2009 Standout
Cobalt‐Catalyzed Twofold Direct C(sp2)−C(sp3) Bond Coupling: Regioselective C‐3 Alkylation of Coumarins with (Cyclo)alkyl Ethers
2016
Bidentate phosphines as ligands in the palladium-catalyzed intramolecular arylation: the intermolecular base-assisted proton abstraction mechanism
2008
Further studies on palladium-catalyzed bismetallative cyclization of enynes in the presence of Bu3SnSiMe3
2003
Synthetic and Mechanistic Studies of Pd-Catalyzed C−H Arylation with Diaryliodonium Salts: Evidence for a Bimetallic High Oxidation State Pd Intermediate
2009
Pd-Catalyzed π-Chelation Assisted ortho-C–H Activation and Annulation of Allylarenes with Internal Alkynes
2013
Ruthenium-Catalyzed Oxidative C–H Bond Olefination of N-Methoxybenzamides Using an Oxidizing Directing Group
2012
Direct Amination of Azoles via Catalytic C−H, N−H Coupling
2009
Palladium/Copper‐Catalyzed Oxidative CH Alkenylation/N‐Dealkylative Carbonylation of Tertiary Anilines
2013
Heterocycle Synthesis via Direct C–H/N–H Coupling
2011
Iron-catalyzed synthesis of heterocycles
2014
Recent developments in palladium-catalysed non-directed coupling of (hetero)arene C–H bonds with C–Z (Z = B, Si, Sn, S, N, C, H) bonds in bi(hetero)aryl synthesis
2017
Copper-mediated direct arylation of benzoazoles with aryl iodides
2008
Catalytic Regiodivergent Kinetic Resolution of Allylic Epoxides: A New Entry to Allylic and Homoallylic Alcohols with High Optical Purity
2004
Iodoarene-catalyzed fluorination and aminofluorination by an Ar-I/HF·pyridine/mCPBA system
2014
Weak O‐Assistance Outcompeting Strong N,N‐Bidentate Directing Groups in Copper‐Catalyzed C−H Chalcogenation
2016
Palladium-Catalyzed 1,2-Addition of Potassium Aryl- and Alkenyltrifluoroborates to Aldehydes using Thioether−Imidazolinium Carbene Ligands
2008
Rhodium-Catalyzed [2 + 2 + 2] Cyclotrimerization in an Aqueous−Organic Biphasic System
2003
Ni-Catalyzed Direct Carboxylation of Benzyl Halides with CO2
2013
Transition Metal-Catalyzed Carbocyclizations in Organic Synthesis
1996
Highly efficient synthesis of functionalized dihydronaphthalenes, tetrahydronaphthalenes, and tetrahydroisoquinolines by iron-catalyzed intramolecular Friedel–Crafts reaction of aryl-containing propargylic alcohols
2009
Functional Group Tolerant Kumada−Corriu−Tamao Coupling of Nonactivated Alkyl Halides with Aryl and Heteroaryl Nucleophiles: Catalysis by a Nickel Pincer Complex Permits the Coupling of Functionalized Grignard Reagents
2009
Ruthenium-Catalyzed C–H Alkynylation of Aromatic Amides with Hypervalent Iodine–Alkyne Reagents
2016
Secondary Phosphine Oxide Preligands for Palladium‐Catalyzed C–H (Hetero)Arylations: Efficient Access to Pybox Ligands
2017
Transition metal-catalyzed intramolecular [4 + 2] cycloadditions: Mechanistic and synthetic investigations
1998
Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
2016 Standout
Direct Cross-Coupling Reaction of Simple Alkenes with Acrylates Catalyzed by Palladium Catalyst
2009
Recent advances in enantioselective copper-catalyzed 1,4-addition
2009 StandoutNobel
Ruthenium-Catalyzed Oxidative Vinylation of Heteroarene Carboxylic Acids with Alkenes via Regioselective C−H Bond Cleavage
2011
Distinct Reactivity of Pd(OTs)2: The Intermolecular Pd(II)-Catalyzed 1,2-Carboamination of Dienes
2008
Synthesis of Phenanthrone Derivatives from sec-Alkyl Aryl Ketones and Aryl Halides via a Palladium-Catalyzed Dual C−H Bond Activation and Enolate Cyclization
2010
Reactions of the 21st Century: Two Decades of Innovative Catalyst Design for Palladium-Catalyzed Cross-Couplings
2015
Enantioselective synthesis through enzymatic asymmetrization
1996
Exceptional Sensitivity of Metal−Aryl Bond Energies to ortho-Fluorine Substituents: Influence of the Metal, the Coordination Sphere, and the Spectator Ligands on M−C/H−C Bond Energy Correlations
2009
Palladium-Catalyzed Benzylic C−H Insertion of 2-Substituted N-Iminopyridinium Ylides
2008
Copper‐Catalyzed Cross‐Dehydrogenative Coupling (CDC) of Alkynes and Benzylic CH Bonds
2010
Copper-Catalyzed Arylation and Alkenylation of Polyfluoroarene C−H Bonds
2008
Ruthenium-Catalyzed Intramolecular [5 + 2] Cycloadditions
2000
Intramolecular Palladium-Catalyzed Alkane C−H Arylation from Aryl Chlorides
2010
Carboxylates as sources of carbon nucleophiles and electrophiles: comparison of decarboxylative and decarbonylative pathways
2012
Palladium-catalyzed cycloreductions of haloene-ynes in the presence of triethylsilane
2003
High-Yielding Palladium-Catalyzed Intramolecular Alkane Arylation: Reaction Development and Mechanistic Studies
2007
FeCl3-Catalyzed 1,2-Addition Reactions of Aryl Aldehydes with Arylboronic Acids
2008
Update 1 of: Synthesis and Functionalization of Indoles Through Palladium-Catalyzed Reactions
2011
Transition-Metal-Catalyzed Reactions in Heterocyclic Synthesis
2004 Standout
Construction of tetracyclic ring systems by Co2(CO)8-catalyzed tandem [2 + 2 + 1]/[2 + 2 + 2] cycloaddition reaction of diynes: a simple one-pot reaction†
1999
Ruthenium-Catalyzed Oxidative C–H Bond Alkenylations in Water: Expedient Synthesis of Annulated Lactones
2011
Selective C−S Bond Formation via Fe-Catalyzed Allylic Substitution
2009
Atom Economical Syntheses of Oxygen Heterocycles via Tandem Palladium-Catalyzed Reactions
2000
C–H arylations of 1,2,3-triazoles by reusable heterogeneous palladium catalysts in biomass-derived γ-valerolactone
2016
Palladium-Catalyzed Intramolecular Coupling of Arenes and Unactivated Alkanes in Air
2008
Non-conventional methodologies for transition-metal catalysed carbon–carbon coupling: a critical overview. Part 1: The Heck reaction
2005
Ruthenium‐Catalyzed Regioselective Cyclization of Aromatic Ketones with Alkynes: An Efficient Route to Indenols and Benzofulvenes
2011
Palladium‐Catalyzed Direct Arylations of 1,2,3‐Triazoles with Aryl Chlorides using Conventional Heating
2008
Iron-Catalyzed Regio- and Stereoselective Substitution of γ,δ-Epoxy-α,β-unsaturated Esters and Amides with Grignard Reagents
2010
Palladium-Catalyzed Alkylation of sp2 and sp3 C−H Bonds with Methylboroxine and Alkylboronic Acids: Two Distinct C−H Activation Pathways
2006
Double C−H Activation: The Palladium-Catalyzed Direct C-Arylation of Xanthines with Arenes
2011
Palladium-Catalyzed C–H Alkenylation of Arenes Using Thioethers as Directing Groups
2012
Low-valent cobalt-catalyzed C–H allylation
2016
Iron-Catalyzed Negishi Coupling Toward an Effective Olefin Synthesis
2009
Highly enantioselective rhodium-catalyzed conjugate addition of arylboronic acids to enones at room temperature
2005 StandoutNobel
Halogen Exchange (Halex) Reaction of 5‐Iodo‐1,2,3‐triazoles: Synthesis and Applications of 5‐Fluorotriazoles
2012
C–H Alkylations of (Hetero)Arenes by Maleimides and Maleate Esters through Cobalt(III) Catalysis
2017
Oxidative Addition of RCO2H and HX to Chiral Diphosphine Complexes of Iridium(I): Convenient Synthesis of Mononuclear Halo-Carboxylate Iridium(III) Complexes and Cationic Dinuclear Triply Halogen-Bridged Iridium(III) Complexes and Their Catalytic Performance in Asymmetric Hydrogenation of Cyclic Imines and 2-Phenylquinoline
2006
Ruthenium‐Catalyzed Oxidative Annulation by Cleavage of CH/NH Bonds
2011
Chiral Diphosphine and Monodentate Phosphorus Ligands on a Spiro Scaffold for Transition-Metal-Catalyzed Asymmetric Reactions
2008
Ruthenium‐Catalyzed Selective Aerobic Oxidative ortho‐Alkenylation of Substituted Phenols with Alkenes through C–H Bond Activation
2013
Cu(I)-catalyzed intramolecular cyclization of ene-carbamates: synthesis of indoles and pyrrolo[2,3-c]pyridines
2005
A simple diamine as ligand in iron-catalyzed regioselective allylic alkylation
2012
Synthesis and Electronic Structure of Bis(imino)pyridine Iron Metallacyclic Intermediates in Iron-Catalyzed Cyclization Reactions
2013
Palladium-Catalyzed Dehydrogenative Direct Arylations of 1,2,3-Triazoles
2010
Cobalt-catalyzed synthesis of quinolines from the redox-neutral annulation of anilides and alkynes
2016
Directed Nickel-Catalyzed Negishi Cross Coupling of Alkyl Aziridines
2013
Ru(II)-Catalyzed Cycloadditions of 1,6-Heptadiynes with Alkenes: New Synthetic Potential of Ruthenacyclopentatrienes as Biscarbenoids in Tandem Cyclopropanation of Bicycloalkenes and Heteroatom-Assisted Cyclocotrimerization of 1,6-Heptadiynes with Heterocyclic Alkenes
2000
Catalytic Regioselective Oxidative Coupling of Furan-2-Carbonyls with Simple Arenes
2012
Direct Functionalization of Nitrogen Heterocycles via Rh-Catalyzed C−H Bond Activation
2008
Recent Progress in Nickel‐Catalyzed Biaryl Coupling
2012
Nickel-catalyzed intramolecular C–H arylation using aryl pivalates as electrophiles
2013
Stereoselective Synthesis of β-Alkylated α-Amino Acids via Palladium-Catalyzed Alkylation of Unactivated Methylene C(sp3)–H Bonds with Primary Alkyl Halides
2013
Iron-Catalyzed Regio- and Stereoselective Ring Opening of [2.2.1]- and [3.2.1]Oxabicyclic Alkenes with a Grignard Reagent
2003
Copper-Catalyzed Arylation of Heterocycle C−H Bonds
2007
Iron‐Catalyzed Allylic C–H Amination of Substituted 1,3‐Dienes
2014
PIDA-Mediated Oxidative C−C Bond Formation: Novel Synthesis of Indoles fromN-Aryl Enamines
2009
Auxiliary-Assisted Palladium-Catalyzed Arylation and Alkylation of sp2 and sp3 Carbon−Hydrogen Bonds
2010
Ligandenbibliotheken für die hocheffiziente Rhodium‐Phosphoramidit‐katalysierte asymmetrische Arylierung von N,N‐Dimethylsulfamoyl‐geschützten Aldiminen
2006 StandoutNobel
Rhodium-Catalyzed Regioselective Olefination Directed by a Carboxylic Group
2011
Copper-Catalyzed Selective ortho-C–H/N–H Annulation of Benzamides with Arynes: Synthesis of Phenanthridinone Alkaloids
2017
Heterogeneous catalytic approaches in C–H activation reactions
2016
Unsaturated Nitriles: Conjugate Additions of Carbon Nucleophiles to a Recalcitrant Class of Acceptors
2003
Copper-Mediated Annulative Direct Coupling of o-Alkynylphenols with Oxadiazoles: A Dehydrogenative Cascade Construction of Biheteroaryls
2011
A Novel Approach to 3-Methylindoles by a Heck/Cyclization/Isomerization Process
2010
Mechanistic Comparison between Pd-Catalyzed Ligand-Directed C−H Chlorination and C−H Acetoxylation
2009
Pd/Norbornene: A Winning Combination for Selective Aromatic Functionalization via C–H Bond Activation
2016
A Concise Access to (Polyfluoroaryl)allenes by Cu-Catalyzed Direct Coupling with Propargyl Phosphates
2012
Palladium-Catalyzed Picolinamide-Directed Alkylation of Unactivated C(sp3)–H Bonds with Alkyl Iodides
2013
RuH2(CO)(PPh3)3-catalyzed arylation of aromatic esters using arylboronates via C–H bond cleavages
2010
A Practical Procedure for Iron‐Catalyzed Cross‐Coupling Reactions of Sterically Hindered Aryl‐Grignard Reagents with Primary Alkyl Halides
2014
Nickel-Catalyzed [4+2+2]-Type Annulation Reaction of Cyclobutanones with Diynes and Enynes
2008
Copper-Mediated Direct Alkoxylation of Arenes Using an N,O-Bidentate Directing System
2014
Cobalt mediated C–H bond functionalization: emerging tools for organic synthesis
2014
Ruthenium-catalyzed aerobic oxidative coupling of alkynes with 2-aryl-substituted pyrroles
2011
Overview of the Mechanistic Work on the Concerted Metallation–Deprotonation Pathway
2010 Standout
Visible‐Light Photocatalysis: Does It Make a Difference in Organic Synthesis?
2018 Standout
Palladium-Catalyzed Direct Oxidative Alkenylation of Azoles
2010
Enantioselective Cobalt‐Catalyzed [6+2] Cycloadditions of Cycloheptatriene with Alkynes
2008
Sequential Transformations in Organic Chemistry: A Synthetic Strategy with a Future
1993
Cobalt‐Catalyzed Mild Ring‐Opening Addition of Arenes C−H Bond to 7‐Oxabicyclic Alkenes
2016
Isolated Organometallic Nickel(III) and Nickel(IV) Complexes Relevant to Carbon–Carbon Bond Formation Reactions
2016
Examination of the Mechanism of Rh2(II)-Catalyzed Carbazole Formation Using Intramolecular Competition Experiments
2009
An Intramolecular Titanium-Catalyzed Asymmetric Pauson−Khand Type Reaction1
1999
Copper-Catalyzed Direct Benzylation or Allylation of 1,3-Azoles with N-Tosylhydrazones
2011
Transition Metal-Catalyzed C–H Amination: Scope, Mechanism, and Applications
2017 Standout
Iridium complex-catalyzed [2+2+2] cycloaddition of α,ω-diynes with monoalkynes: a new and efficient catalyst for cyclotrimerization of alkynes
2001
Palladium-Catalyzed Oxidative C−H Bond and C═C Double Bond Cleavage: C-3 Acylation of Indolizines with α,β-Unsaturated Carboxylic Acids
2011
Direct α‐Arylation of Ethers through the Combination of Photoredox‐Mediated CH Functionalization and the Minisci Reaction
2014
Direct arylation of oxazole and benzoxazole with aryl or heteroaryl halides using a palladium–diphosphine catalyst
2007
Innovative Catalytic Protocols for the Ring‐Closing Friedel–Crafts‐Type Alkylation and Alkenylation of Arenes
2006
Rhodium-Catalyzed Tandem Conjugate Addition−Mannich Cyclization Reaction: Straightforward Access to Fully Substituted Tetrahydroquinolines
2008
Cationic Cobalt(III) Catalyzed Indole Synthesis: The Regioselective Intermolecular Cyclization of N‐Nitrosoanilines and Alkynes
2016
Mild and Phosphine-Free Iron-Catalyzed Cross-Coupling of Nonactivated Secondary Alkyl Halides with Alkynyl Grignard Reagents
2014
Palladium-Catalyzed Direct Arylation of Aryl(azaaryl)methanes with Aryl Halides Providing Triarylmethanes
2007
Toxicity of Metal Compounds: Knowledge and Myths
2017
Palladium-Catalyzed Synthesis of Benzimidazoles and Quinazolinones from Common Precursors
2012
Ligand-Accelerated C−H Activation Reactions: Evidence for a Switch of Mechanism
2010
Cu-catalyzed controllable C–H mono-/di-/triarylations of imidazolium salts for ionic functional materials
2017
Lewis Acid Promoted [2 + 1] Cycloaddition Reactions of 1-Seleno-2-silylethene with Tricarbonyl-Substituted Olefins
1997
Palladium-Catalyzed Direct C−H Arylation of N-Iminopyridinium Ylides: Application to the Synthesis of (±)-Anabasine
2007
A Molecular Elevator
2004 StandoutScienceNobel
Direct C−H Transformation via Iron Catalysis
2010 Standout
Asymmetric C–H functionalization of cyclopropanes using an isoleucine-NH2 bidentate directing group
2015
Room-Temperature Direct Arylation of Polyfluorinated Arenes under Biphasic Conditions
2010
A Meta-Selective Copper-Catalyzed C–H Bond Arylation
2009 Science
Ru/Ag-Catalyzed Oxidative Alkenylation of Benzamides and Phenylazoles through Regioselective C–H Bond Cleavage
2012
Ruthenium Chloride as an Efficient Catalytic Precursor for Hydroarylation Reactions via C−H bond Activation
2010
Synthesis of Indolines via Pd(II)-Catalyzed Amination of C–H Bonds Using PhI(OAc)2 as the Bystanding Oxidant
2013
Copper‐Catalyzed Highly Regioselective Oxidative CH Bond Amidation of 2‐Arylpyridine Derivatives and 1‐Methylindoles
2010
Copper-Catalyzed C–H Functionalization Reactions: Efficient Synthesis of Heterocycles
2014
Nickel-Catalyzed Oxidative Coupling of Unactivated C(sp3)–H Bonds in Aliphatic Amides with Terminal Alkynes
2016
Enantioselective Synthesis of Spiropentanes from Hydroxymethylallenes
2001
Acetylene Cyclotrimerization with an Iron(II) Bis(imino)pyridine Catalyst
2012
Assisted Ruthenium-Catalyzed C−H Bond Activation: Carboxylic Acids as Cocatalysts for Generally Applicable Direct Arylations in Apolar Solvents
2008
Catalyst and base controlled site-selective sp2 and sp3 direct arylation of azine N-oxides
2008
Synthesis of Substituted Indenes through Iron‐Catalyzed Annulation of Benzylic Alcohols with Alkynes
2011
Weakly Coordinating Directing Groups for Ruthenium(II)‐ Catalyzed CH Activation
2014
Heteromultimetallic catalysis for sustainable organic syntheses
2017
A Direct Intramolecular C−H Amination Reaction Cocatalyzed by Copper(II) and Iron(III) as Part of an Efficient Route for the Synthesis of Pyrido[1,2-a]benzimidazoles fromN-Aryl-2-aminopyridines
2010
Modular Synthesis of Benzimidazole-Fused Phenanthridines from 2-Arylbenzimidazoles and o-Dibromoarenes by a Palladium-Catalyzed Cascade Process
2014
Nickel-Catalyzed Aromatic C–H Alkylation with Secondary or Tertiary Alkyl–Bromine Bonds for the Construction of Indolones
2013
Cobalt‐Catalyzed Diastereoselective [4+2] Annulation of Phosphinamides with Heterobicyclic Alkenes at Room Temperature
2017
Direct Arylations of 2H-Indazoles On Water
2009
Pd-catalyzed oxidative cross-coupling between two electron rich heteroarenes
2013
Dicobalt Octacarbonyl-Catalyzed Tandem [2 + 2 + 1] and [2 + 2 + 2] Cycloaddition Reaction of Diynes with Two Phenylacetylenes under CO
2000
Regioselective Ortho Olefination of Aryl Sulfonamide via Rhodium-Catalyzed Direct C–H Bond Activation
2014
Pd(0) Mechanism of Palladium-Catalyzed Cyclopropanation of Alkenes by CH2N2: A DFT Study
2002
Rhodium-Catalyzed C−C Bond Formation via Heteroatom-Directed C−H Bond Activation
2009 Standout
Novel reductive coupling cyclization of 1,1-dicyanoalkenes promoted by metallic samarium in aqueous media
1998
Monodentate phosphoramidites; versatile ligands in catalytic asymmetric intramolecular Heck reactions
2003 StandoutNobel
Highly efficient aerobic ruthenium-catalyzed oxidative cross-dehydrogenative coupling for sp3–sp3 carbon–carbon bond formation
2009
Palladium-catalyzed selective oxidative olefination and arylation of 2-pyridones
2012
Silanol: A Traceless Directing Group for Pd-Catalyzed o-Alkenylation of Phenols
2011
Heterocyclic Nanographenes and Other Polycyclic Heteroaromatic Compounds: Synthetic Routes, Properties, and Applications
2016 Standout
Allylic Carbon–Carbon Double Bond Directed Pd-Catalyzed Oxidative ortho-Olefination of Arenes
2012
Chemoselective Activation of sp3 vs sp2 C–H Bonds with Pd(II)
2014
Transesterification catalyzed by iron(III) β-diketonate species
2011
Rhodium catalyzed intramolecular [4+2] cycloisomerization reactions
1998
Cobalt-Catalyzed Hydroarylation of Alkynes through Chelation-Assisted C−H Bond Activation
2010
Application of Rhodium Complexes of Chiral Diphenylphosphino‐Functionalized N‐Heterocyclic Carbenes as Catalysts in Enantioselective Conjugate Additions of Arylboronic Acids
2005
Low-Valent Cobalt Catalysis: New Opportunities for C–H Functionalization
2014
Lamellarins and Related Pyrrole-Derived Alkaloids from Marine Organisms
2007 Standout
FeCl3 Catalyzed Prins-Type Cyclization for the Synthesis of Highly Substituted Indenes: Application to the Total Synthesis of (±)-Jungianol and epi-Jungianol
2013
Palladium-catalyzed oxidative C–H/C–H cross-couplings of thiazolo[5,4-d]pyrimidine with aromatic (hetero)cycles
2014
Ruthenium-Catalyzed Highly Regioselective Cyclization of Ketoximes with Alkynes by C–H Bond Activation: A Practical Route to Synthesize Substituted Isoquinolines
2012
Highly Efficient and Versatile Synthesis of Polyarylfluorenes via Pd-Catalyzed C−H Bond Activation
2009
C−H Activation of Imines by Trimethylphosphine-Supported Iron Complexes and Their Reactivities
2009
One-pot synthesis of benzofused heteroaryl azoles via tandem C-heteroatom coupling/C–H activation of azoles
2011
The first catalytic asymmetric total synthesis of ent-hyperforin
2010
Highly regioselective cyclotrimerization of terminal alkynes catalyzed by Fe(II) complexes bearing 2-(benzimidazolyl)-6-(1-(arylimino)ethyl)pyridines
2010
Copper-catalyzed asymmetric allylic substitution reactions with organozinc and Grignard reagents
2008 StandoutNobel
New functionalized N‐heterocyclic carbene ligands for arylation of benzaldehydes
2009
One‐Pot Synthesis of Benzimidazo[1,2‐f]phenanthridines by Cascade Palladium‐Catalyzed N‐Arylation and Intramolecular C–H Coupling
2013
Versatile Pyrrole Synthesis through Ruthenium(II)-Catalyzed Alkene C–H Bond Functionalization on Enamines
2012
Palladium-Catalyzed Enantioselective Conjugate Addition of Arylboronic Acids
2005
Iron-Catalyzed, Microwave-Promoted, One-Pot Synthesis of 9-Substituted Xanthenes by a Cascade Benzylation−Cyclization Process
2009
Intramolecular benzylic C–H activation: palladium-catalyzed synthesis of hexahydromethanofluorenes
2000
Direct ortho‐Acyloxylation of Arenes and Alkenes by Cobalt Catalysis
2017
Autocatalysis for C–H Bond Activation by Ruthenium(II) Complexes in Catalytic Arylation of Functional Arenes
2011
Palladium-catalyzed N-(2-pyridyl)sulfonyl-directed C(sp3)–H γ-arylation of amino acid derivatives
2012
Cobalt-Catalyzed Cross-Coupling Reactions
2010
Catalytic C–C coupling through C–H arylation of arenes or heteroarenes
2009
Rhodium‐Catalyzed N‐tert‐Butoxycarbonyl (Boc) Amination by Directed CH Bond Activation
2016
Dehydrative Direct Arylations of Arenes with Phenols via Ruthenium-Catalyzed C−H and C−OH Bond Functionalizations
2008
Efficiency of a Ruthenium Catalyst in Metathesis Reactions of Sulfur-Containing Compounds
2002
Catalytic Asymmetric Reductive Acyl Cross-Coupling: Synthesis of Enantioenriched Acyclic α,α-Disubstituted Ketones
2013
Highly Enantio‐ and Diastereoselective One‐Pot Reactions in Aqueous Media: Combined Asymmetric Rh‐Catalyzed Conjugate Addition/Metal‐Mediated Allylation
2006 StandoutNobel
Palladium(II)-Catalyzed Dehydrogenative Alkenylation of Cyclic Enaminones via the Fujiwara–Moritani Reaction
2011
Direct Arylation of Arene C−H Bonds by Cooperative Action of NHCarbene−Ruthenium(II) Catalyst and Carbonate via Proton Abstraction Mechanism
2008
Palladium N‐heterocyclic‐carbene‐catalyzed ortho‐arylation of benzaldehyde derivatives
2008
TBDPS and Br-TBDPS Protecting Groups as Efficient Aryl Group Donors in Pd-Catalyzed Arylation of Phenols and Anilines
2009
Palladium-Catalyzed Ligand-Directed C−H Functionalization Reactions
2010 Standout
Iron‐Catalyzed Direct Synthesis of Densely Substituted Benzofurans and Naphthopyrans from Phenolic Compounds and Propargylic Alcohols
2013
Ligand-Promoted C-3 Selective C–H Olefination of Pyridines with Pd Catalysts
2011
Dual C–H activations of electron-deficient heteroarenes: palladium-catalyzed oxidative cross coupling of thiazoles with azine N-oxides
2012
A Catalytic, Brønsted Base Strategy for Intermolecular Allylic C−H Amination
2009
Palladium-Catalyzed Hydroalkylation of Styrenes with Organozinc Reagents To Form Carbon−Carbon sp3−sp3Bonds under Oxidative Conditions
2009
Room-Temperature Regioselective C−H/Olefin Coupling of Aromatic Ketones Using an Activated Ruthenium Catalyst with a Carbonyl Ligand and Structural Elucidation of Key Intermediates
2010
Highly Selective Biaryl Cross-Coupling Reactions between Aryl Halides and Aryl Grignard Reagents: A New Catalyst Combination ofN-Heterocyclic Carbenes and Iron, Cobalt, and Nickel Fluorides
2009
Pd-Catalyzed sequential β-C(sp3)–H arylation and intramolecular amination of δ-C(sp2)–H bonds for synthesis of quinolinones via an N,O-bidentate directing group
2016
Transition‐Metal‐Catalyzed Direct C–H Alkenylation, Alkynylation, Benzylation, and Alkylation of (Hetero)arenes
2010
Asymmetric Transition Metal-Catalyzed Allylic Alkylations
1996 Standout
Cyclic Carbopalladation. A Versatile Synthetic Methodology for the Construction of Cyclic Organic Compounds
1996 StandoutNobel
Iron-catalyzed arylation of α-aryl-α-diazoesters
2016
Ruthenium-Catalyzed Oxidative C–H Alkenylations of Anilides and Benzamides in Water
2012
Methylenecyclopropane Annulation by Manganese(I)‐Catalyzed Stereoselective C−H/C−C Activation
2017
Rhodium(II)‐Catalyzed Nondirected Oxidative Alkenylation of Arenes: Arene Loading at One Equivalent
2014
Palladium‐Catalyzed/Lewis Acid‐Promoted Alkene Dimerization and Cross‐Coupling with Alcohols via CH Bond Activation
2008
Stereoselective Synthesis of Chiral α‐Amino‐β‐Lactams through Palladium(II)‐Catalyzed Sequential Monoarylation/Amidation of C(sp3)H Bonds
2013
Palladium-Catalyzed Method for the Synthesis of Carbazoles via Tandem C−H Functionalization and C−N Bond Formation
2008
Twofold C−H Functionalization: Palladium-Catalyzed Ortho Arylation of Anilides
2008
Total Syntheses of Amphidinolide X and Y
2006
Direct ortho-arylation of 2-arylbenzoxazoles via C–H activation
2008
An Approach to Five‐Membered Lactams from Aliphatic Amides and Terminal Acetylenes by Nickel Catalysis
2016
Rhodium-Catalyzed Mono- and Divinylation of 1-Phenylpyrazoles and Related Compounds via Regioselective C−H Bond Cleavage
2009
Nickel-Catalyzed Direct Arylation of Azoles with Aryl Bromides
2009
IrCl3 or FeCl3-catalyzed convenient synthesis of 3-hydroxyphthalates
2011
Catalytic Asymmetric γ-Alkylation of Carbonyl Compounds via Stereoconvergent Suzuki Cross-Couplings
2011
Deproto-metallation using mixed lithium–zinc and lithium–copper bases and computed CH acidity of 2-substituted quinolines
2014
Regiocontrolled Direct C−H Arylation of Indoles at the C4 and C5 Positions
2017
Further Studies on Nickel-Promoted or -Catalyzed Cyclization of 1,3-Diene and a Tethered Carbonyl Group
2000
Copper-Catalyzed Oxidative Coupling of Benzylic C−H Bonds with 1,3-Dicarbonyl Compounds
2008
Efficient synthesis of trisubstituted alkenes in an aqueous–organic system using a versatile and recyclable Rh/ m -TPPTC catalyst
2004
Nickel-Catalyzed Coupling Reactions of Alkyl Electrophiles, Including Unactivated Tertiary Halides, to Generate CarbonâBoron Bonds
2012
Synthesis and biological evaluation of bryostatin analogues: the role of the A-ring
2000
Pd(ii )-catalyzed C(sp3)–H arylation of amino acid derivatives with click-triazoles as removable directing groups
2015
Palladium-Catalyzed Regioselective Oxidative Coupling of Indoles and One-Pot Synthesis of Acetoxylated Biindolyls
2009
Bis(diisopropylphosphinomethyl)amine Nickel(II) and Nickel(0) Complexes: Coordination Chemistry, Reactivity, and Catalytic Decarbonylative C–H Arylation of Benzoxazole
2013
Regioselective Oxidative Arylation of Indoles Bearing N-Alkyl Protecting Groups: Dual C−H Functionalization via a Concerted Metalation−Deprotonation Mechanism
2010
Iron-Catalyzed Direct Arylation through Directed C−H Bond Activation
2008
Ruthenium-Catalyzed C–H Bond Arylations of Arenes Bearing Removable Directing Groups via Six-Membered Ruthenacycles
2012
Transition metal-free direct amination of benzoxazoles using formamides as nitrogen sources
2014
A Palladium-Catalyzed Regio- and Stereoselective Four-Component Coupling Reaction
2005
Selective C−H Functionalizations by Electrochemical Reactions with Palladium Catalysts
2017
Cu(ii )-catalyzed C6-selective C–H thiolation of 2-pyridones using air as the oxidant
2016
Synthesis of Pyrroles, Indoles, and Carbazoles through Transition‐Metal‐Catalyzed CH Functionalization
2013
A Practical Synthesis of (+)-Biotin through Palladium Hydroxide on Charcoal-catalyzed Fukuyama Coupling Reaction
2002
Silver-Catalyzed Csp−H and Csp−Si Bond Transformations and Related Processes
2008
Palladium(II)-Catalyzed Oxidative C–H/C–H Coupling and Eliminative SNH Reactions in Direct Functionalization of Imidazole Oxides with Indoles
2012
Formal Total Synthesis of (±)-γ-Lycorane and (±)-1-Deoxylycorine Using the [4+2]-Cycloaddition/Rearrangement Cascade of Furanyl Carbamates
2001
Pd-catalyzed dehydrogenative cross-coupling of pyridine-N-oxides with uracils
2014
Amine directed Pd(ii )-catalyzed C–H bond functionalization under ambient conditions
2010
Palladium-catalyzed [3+2] cycloaddition of alkylidenecyclopropanes with imines
2001
Cobalt(II)-Catalyzed Oxidative C–H Alkenylations: Regio- and Site-Selective Access to Isoindolin-1-one
2015
Direct (Hetero)Arylation: A New Tool for Polymer Chemists
2013
Palladium-Catalyzed Bismetallative Cyclization of Enynes
2001
Cobalt-Catalyzed Decarboxylative C–H (Hetero)Arylation for the Synthesis of Arylheteroarenes and Unsymmetrical Biheteroaryls
2017
Copper-Catalyzed Direct Sulfoximination of Azoles and Polyfluoroarenes under Ambient Conditions
2010
Mechanistic Analysis of Azine N-Oxide Direct Arylation: Evidence for a Critical Role of Acetate in the Pd(OAc)2 Precatalyst
2010
Synthesis of Functionalized Spiroindolines via Palladium-Catalyzed Methine C–H Arylation
2013
Challenge and progress: palladium-catalyzed sp3 C–H activation
2011
Recent advances in syntheses of carbocycles and heterocycles via homogeneous gold catalysis. Part 2: Cyclizations and cycloadditions
2008
Asymmetric Synthesis of Highly Functionalized 8-Oxabicyclo[3.2.1]octene Derivatives
1996
Ir-catalyzed highly selective addition of pyridyl C–H bonds to aldehydes promoted by triethylsilane
2010
Nickel, Manganese, Cobalt, and Iron-Catalyzed Deprotonative Arene Dimerization
2010
Rhodium-Catalyzed One-Pot Synthesis of Substituted Pyridine Derivatives from α,β-Unsaturated Ketoximes and Alkynes
2007
Iron‐Catalyzed Nitrogen‐Directed Coupling of Arene and Aryl Bromides Mediated by Metallic Magnesium
2012
Iron-Catalyzed Intermolecular [2π + 2π] Cycloaddition
2011
Reactions of allylic carbonates catalyzed by palladium, rhodium, ruthenium, molybdenum, and nickel complexes; allylation of carbonucleophiles and decarboxylation- dehydrogenation
1985
Direct (Hetero)arylation Polymerization: Simplicity for Conjugated Polymer Synthesis
2016
An organic cation as a silver(i ) analogue for the arylation of sp2 and sp3 C–H bonds with iodoarenes
2014
[3+2] Cycloaddition Reactions of Cyclopropyl Imines with Enones
2007
Ruthenium-Catalyzed Cyclization of Aromatic Nitriles with Alkenes: Stereoselective Synthesis of (Z)-3-Methyleneisoindolin-1-ones
2014
Enantioselective Cobalt-Catalyzed Transformations
2014
Switching the Regioselectivity of Direct C–H Arylation of 1,3‐Dimethyluracil
2009
Iron-Catalyzed [2π + 2π] Cycloaddition of α,ω-Dienes: The Importance of Redox-Active Supporting Ligands
2006
Preparation of indoles via iron catalyzed direct oxidative coupling
2010
Fe(III)-Catalyzed Radical Cyclization of Cyclopropanone Thioacetal
2000
Nickel-Catalyzed C–H/C–O Coupling of Azoles with Phenol Derivatives
2011
First Demonstration of Helical Chirality in 1,4-Disubstituted (Z,Z)-1,3-Dienes: R3Si−SnR‘3-Mediated Cyclization of 1,6-Diynes
2000
Synthesis of Alkenyl Sulfides Through the Iron-Catalyzed Cross-Coupling Reaction of Vinyl Halides with Thiols
2012
(Pentamethylcyclopentadienyl)cobalt(III)‐Catalyzed Oxidative [4+2] Annulation of NH Imines with Alkynes: Straightforward Synthesis of Multisubstituted Isoquinolines
2016
Efficient Iron/Copper Cocatalyzed Alkynylation of Aryl Iodides with Terminal Alkynes
2008
Sequentielle Transformationen in der Organischen Chemie eine Synthesestrategie mit Zukunft
1993
Works of Mark Lautens being referenced
Enantioselective Total Synthesis of (+)‐Homochelidonine by a PdII‐Catalyzed Asymmetric Ring‐Opening Reaction of a meso‐Azabicyclic Alkene with an Aryl Boronic Acid
2006
Domino Rhodium‐Catalyzed Alkyne Arylation/Palladium‐Catalyzed N Arylation: A Mechanistic Investigation
2011
Sequential Rhodium/Palladium Catalysis: Enantioselective Formation of Dihydroquinolinones in the Presence of Achiral and Chiral Ligands
2014
Synthesis of 1,2,3-triazole-fused heterocycles viaPd-catalyzed cyclization of 5-iodotriazoles
2011
Synthesis in the Key of Catellani: Norbornene-Mediated ortho C–H Functionalization
2009
Asymmetric Synthesis of Bryostatin 2
1998
Rhodium‐Catalyzed Enantioselective Nucleophilic Fluorination: Ring Opening of Oxabicyclic Alkenes
2012
Chemodivergence in Enantioselective Desymmetrization of Diazabicycles: Ring‐Opening versus Reductive Arylation
2008
Efficient Synthesis of Benzothiophenes by an Unusual Palladium‐Catalyzed Vinylic CS Coupling
2009
Halide Effects in Transition Metal Catalysis
2002
A Conjunctive Carboiodination: Indenes by a Double Carbopalladation–Reductive Elimination Domino Process
2012
Expeditious Synthesis of Tetrasubstituted Helical Alkenes by a Cascade of Palladium‐Catalyzed CH Activations
2012
Exploiting the Divergent Reactivity of Aryl–Palladium Intermediates for the Rapid Assembly of Fluorene and Phenanthrene Derivatives
2009
Construction of Nitrogen‐Containing Heterocycles by CH Bond Functionalization
2009
Palladium‐Catalyzed Domino Direct Arylation/N‐Arylation: Convenient Synthesis of Phenanthridines
2009
Synthesis of 2-Vinylic Indoles and Derivatives via a Pd-Catalyzed Tandem Coupling Reaction
2006
Synergistic Steric Effects in the Development of a Palladium‐Catalyzed Alkyne Carbohalogenation: Stereodivergent Synthesis of Vinyl Halides
2014
Stereochemical and Mechanistic Investigations of a Palladium‐Catalyzed Annulation of Secondary Alkyl Iodides
2007
Mechanistic Studies of Pd‐Catalyzed Regioselective Aryl CH Bond Functionalization with Strained Alkenes: Origin of Regioselectivity
2011
Palladium-catalysed norbornene-mediated C–H functionalization of arenes
2015
Total Synthesis of (+)‐Linoxepin by Utilizing the Catellani Reaction
2013
Rh/Pd Catalysis with Chiral and Achiral Ligands: Domino Synthesis of Aza‐Dihydrodibenzoxepines
2013
Diastereoselective Benzylic Arylation of Tetralins
2009
The Norbornene Shuttle: Multicomponent Domino Synthesis of Tetrasubstituted Helical Alkenes through Multiple CH Functionalization
2009
Secondary Alkyl Halides in Transition‐Metal‐Catalyzed Cross‐Coupling Reactions
2009
The Use of Silyl Ketene Acetals and Enol Ethers in the Catalytic Enantioselective Alkylative Ring Opening of Oxa/Aza Bicyclic Alkenes
2014
Intramolecular cross-coupling of gem-dibromoolefins: a mild approach to 2-bromo benzofused heterocycles
2009
Studies in the Directed Cyclopropanation of .alpha.-Allenic Alcohols
1994
The Role of Reversible Oxidative Addition in Selective Palladium(0)-Catalyzed Intramolecular Cross-Couplings of Polyhalogenated Substrates: Synthesis of Brominated Indoles
2010
Theoretical study of Pd(0)-catalyzed carbohalogenation of alkenes: mechanism and origins of reactivities and selectivities in alkyl halide reductive elimination from Pd(ii) species
2012
Palladium-Catalyzed Sequential Alkylation−Alkenylation Reactions. Application to the Synthesis of 2-Substituted-4-Benzoxepines and 2,5-Disubstituted-4-Benzoxepines
2002
Computational and 13C Investigations of the Diazadienes and Oxazadienes Formed via the Rearrangement of Methylenecyclopropyl Hydrazones and Oximes
2014
Rhodium-catalyzed asymmetric ring opening reactions of oxabicyclic alkenes: Catalyst and substrate studies leading to a mechanistic working model
2004
Reagent-Controlled Regiodivergent Resolution of Unsymmetrical Oxabicyclic Alkenes Using a Cationic Rhodium Catalyst
2008
CuI-Catalyzed Tandem Intramolecular Amidation Using gem-Dibromovinyl Systems
2006
Exploiting Distal Reactivity of Coumarins: A Rhodium‐Catalyzed Vinylogous Asymmetric Ring‐Opening Reaction
2016
A Highly Selective Tandem Cross-Coupling ofgem-Dihaloolefins for a Modular, Efficient Synthesis of Highly Functionalized Indoles
2007
Modular Synthesis of Naphthothiophenes by Pd-Catalyzed Tandem Direct Arylation/Suzuki Coupling
2011
Transition Metal Catalyzed Stereospecific Intramolecular [3 + 2] Cycloadditions of Methylenecyclopropanes with Alkynes
1996
Stereochemical Control in Metal-Catalyzed [3 + 2] Cycloadditions of Methylenecyclopropanes
1994
Stereochemical and Mechanistic Investigations of a Palladium‐Catalyzed Annulation of Secondary Alkyl Iodides
2007
Regioselective Palladium‐Catalyzed Hydrostannylation of Unsymmetrical Oxabicyclic Alkenes
1996
Rhodium-Catalyzed Asymmetric Allylic Substitution with Boronic Acid Nucleophiles
2006
Tandem alkylation-cycloadditions. Control by transition-metal templates
1984
Regioselective cyclopropanation of .alpha.-allenic alcohols. An efficient route to alkylidenecyclopropanes
1993
Palladium-Catalyzed Annulation of Haloanilines and Halobenzamides Using Norbornadiene as an Acetylene Synthon: A Route to Functionalized Indolines, Isoquinolinones, and Indoles
2009
A New Route to Fused Aromatic Compounds by Using a Palladium-Catalyzed Alkylation - Alkenylation Sequence
2000
Ring Opening in the Hydrostannation of Methylenecyclopropanes: Effect of the Catalyst and Substrate
1996
Cobalt-Catalyzed [2.pi. + 2.pi. + 2.pi.] (Homo-Diels-Alder) and [2.pi. + 2.pi. + 4.pi.] Cycloadditions of Bicyclo[2.2.1]hepta-2,5-dienes
1995
Rhodium-catalysed asymmetric ring opening of oxabicyclic alkenes with heteroatom nucleophiles
2001
Formation of Homoallyl Stannanes via Palladium-Catalyzed Stannylative Cyclization of Enynes
2000
Rhodium‐Catalyzed Enantioselective Nucleophilic Fluorination: Ring Opening of Oxabicyclic Alkenes
2012
Chemodivergence in Enantioselective Desymmetrization of Diazabicycles: Ring‐Opening versus Reductive Arylation
2008
Allylic Substitution Reactions
2005
Selectively Substituted Thiophenes and Indoles by a Tandem Palladium-Catalyzed Multicomponent Reaction
2006
Opening of oxabicyclo[3.2.1]octenes with organolithium reagents. A route to cyclic and acyclic compounds with high stereocontrol
1990
Diastereoselectivity in the Cyclopropanation of 3,3-Bimetallic Allylic Alcohols. Preparation of Diastereomeric Cyclopropyl Carbinols via a Simple Oxidation-Reduction Sequence
1995
ChemInform Abstract: Rhodium‐Catalyzed Asymmetric Alcoholysis and Aminolysis of Oxabenzonorbornadiene: A New Enantioselective Carbon—Heteroatom Bond Forming Process.
2000
Mechanistic Studies of the Palladium-Catalyzed Ring Opening of Oxabicyclic Alkenes with Dialkylzinc
2001
Multicomponent-Multicatalyst Reactions (MC)2R: Efficient Dibenzazepine Synthesis
2013
Pd-Catalyzed Tandem C−N/C−C Coupling of gem-Dihalovinyl Systems: A Modular Synthesis of 2-Substituted Indoles
2005
Oxabicyclo[3.2.1]oct-6-enes as Templates for the Stereoselective Synthesis of Polypropionates: Total Synthesis of Callystatin A and C19-epi-Callystatin A
2002
Transition Metal-Catalyzed Enantioselective Ring-Opening Reactions of Oxabicyclic Alkenes
2002
Heterogenkatalysierte, regioselektive Hydrostannylierung von Alkenen
1996
Synthesis of Tricyclic Heterocycles via a Tandem Aryl Alkylation/Heck Coupling Sequence
2006
Synthesis of Substituted Benzoxacycles via a Domino Ortho-Alkylation/Heck Coupling Sequence
2006
Regiochemical diversity in allylic alkylations via molybdenum catalysts
1987
Cyclization via isomerization: a palladium(2+)-catalyzed carbocyclization of 1,6-enynes to 1,3- and 1,4-dienes
1985
C−H Bond Functionalization in the Synthesis of Fused 1,2,3-Triazoles
2010
Domino rhodium(I)-catalysed reactions for the efficient synthesis of substituted benzofurans and indoles
2010
Application of the Palladium‐Catalysed Norbornene‐Assisted Catellani Reaction Towards the Total Synthesis of (+)‐Linoxepin and Isolinoxepin
2014
Rhodium-Catalyzed Asymmetric Ring Opening of Oxabicyclic Alkenes with Sulfur Nucleophiles
2004
Use of γ-Carboxy-α,β-unsaturated Aldehydes as Synthetic Equivalents of β,γ-Unsaturated Aldehydes in a Novel Stereoselective Approach to Diketides
1999
The Utility of the Homo Diels-Alder Reaction in the Synthesis of Natural Product Skeletons: A Cycloaddition-Fragmentation-Cyclization Sequence to Diquinanes and Triquinanes
1998
Asymmetric synthesis of the lactone moiety of mevinic acid
1995
Rhodium-Catalyzed Tandem Cyclization: Formation of 1H-Indenes and 1-Alkylideneindans from Arylboronate Esters in Aqueous Media
2004
Palladium-Catalyzed Enantioselective Alkylative Ring Opening
2000
Diastereoselective Ring Closing Metathesis Reactions: Synthesis of Bicyclic Diallylic Alcohols and Ethers
1999
Palladium-Catalyzed Domino C−C/C−N Coupling Using a Norbornene Template: Synthesis of Substituted Benzomorpholines, Phenoxazines, and Dihydrodibenzoxazepines
2010
Total Synthesis of Bryostatin 2
1999
Regioselektive Palladium‐katalysierte Hydrostannylierung von unsymmetrischen Oxabicycloalkenen
1996
Palladium-Catalyzed Sequential Alkylation−Alkenylation Reactions and Their Application to the Synthesis of Fused Aromatic Rings
2001
Expedient Synthesis of Chiral Oxazolidinone Scaffolds via Rhodium-Catalyzed Asymmetric Ring-Opening with Sodium Cyanate
2013
Practical synthesis of acetophenones from phenoltriflates
2001
Metal-Catalyzed Hydrostannations
2000
Synthesis of Highly Functionalized Pyrrolidines via a Selective Iodide-Mediated Ring Expansion of Methylenecyclopropyl Amides
2008
The effect of remote oxygens on the ring-opening reactions of oxabicyclic compounds with organolithium reagents. Synthesis of the C21–C27 segment of rifamycin S
1992
Annulation via alkylation-Alder ene cyclizations. Palladium-catalyzed cycloisomerization of 1,6-enynes
1991
Silver-Promoted Domino Pd-Catalyzed Amination/Direct Arylation: Access to Polycyclic Heteroaromatics
2008
Nickel-Catalyzed Hydroalumination of Oxabicyclic Alkenes. Ligand Effects on the Regio- and Enantioselectivity
1995
Palladium-Catalyzed Intramolecular [3 + 2] Cycloadditions of Methylenecyclopropanes With Alkenes: Diastereomeric Methylenecyclopropanes Exhibit Complementary Facial Selectivity
1996
Studies in the Transmetalation of Cyclopropyl, Vinyl, and Epoxy Stannanes
1995
Palladium-Catalyzed Intramolecular Coupling between Aryl Iodides and Allyl Moieties via Thermal and Microwave-Assisted Conditions
2004
Rh(I)-Catalyzed Ring-Opening of Hetaryne−Furan Diels−Alder Adducts: Rapid Access to Stereochemically Defined Heterocyclic Scaffolds
2011
Synthesis of Benzannulated N-Heterocycles by a Palladium-Catalyzed C−C/C−N Coupling of Bromoalkylamines
2007
Regioselective Rhodium(I)-Catalyzed Hydroarylation of Protected Allylic Amines with Arylboronic Acids
2010
Palladium-catalyzed ring-forming reactions: Methods and applications
2006
Regioselective nucleophilic ring opening of oxabicyclic compounds
1993
Application of Secondary Alkyl Halides to a Domino Aryl Alkylation Reaction for the Synthesis of Aromatic Heterocycles
2008
The Hydroxyl‐Directed Hydrogenation of Vinylstannanes and Silanes: A Highly Diastereoselective Route to β‐Stannyl and β‐Silyl Alcohols
1992
Transition Metal-Mediated Cycloaddition Reactions
1996 Standout
Synthesis of Polycyclic Heterocycles via a One-Pot Ortho Alkylation/Direct Heteroarylation Sequence
2006
A Palladium-Catalyzed Alkylation/Direct Arylation Synthesis of Nitrogen-Containing Heterocycles
2008
Pd-Catalyzed Cycloisomerization to 1,2- Dialkylidenecycloalkanes. 1
1994
Silylstannation-Cyclization of 1,6-Enynes using Palladium(0) and Palladium(II) Catalysis
2002
Aryl−Aryl Bond Formation by Transition-Metal-Catalyzed Direct Arylation
2007 Standout
Rhodium-Catalyzed Asymmetric Ring Opening of Oxabicyclic Alkenes with Phenols
2000
Regioselective Hydrostannation of Allenes Catalyzed by Pd(OH)2/C
1997
Stereoselectivity in the homo-Diels–Alder reaction: effect of a remote 7-substituent on nickel-catalysed cycloadditions
1994
Diastereoselektive Ringschlußmetathese: Synthese bicyclischer Diallylalkohole und -ether
1999
Preparation of Annulated Nitrogen-Containing Heterocycles via a One-Pot Palladium-Catalyzed Alkylation/Direct Arylation Sequence
2006
Rhodium-Catalyzed Ring-Opening Reactions of N-Boc-Azabenzonorbornadienes with Amine Nucleophiles
2006
Aromatic ortho-Benzylation Reveals an Unexpected Reductant
2008
Metal catalyzed hydrometalations and their applications in synthesis
1998
Enantioselective Ring Opening of Aza and Oxabicyclic Alkenes with Dimethylzinc
2000
Enantioselective cobalt-catalyzed [4.pi.+2.pi.+2.pi.] cycloadditions
1993
A Highly Diastereoselective MgI2-Mediated Ring Expansion of Methylenecyclopropanes
2004
Synthesis of β,γ-Unsaturated Lactams via a Magnesium Iodide Promoted Ring Expansion of Secondary Methylenecyclopropyl Amides
2006
Diastereoselective Intramolecular Friedel–Crafts Alkylation of Tetralins
2011
Der Einfluss von Halogenidionen in der Übergangsmetallkatalyse
2002
A New Strategy to Bicyclo[5.3.0]decenes via Anionic Intramolecular Ring Opening of Oxabicyclo[3.2.1] Compounds
1995
Palladium-Catalyzed Annulation of Aryl Heterocycles with Strained Alkenes
2007
The versatile role of norbornene in C–H functionalization processes: concise synthesis of tetracyclic fused pyrroles via a threefold domino reaction
2008
General Strategy toward the Tetrahydronaphthalene Skeleton. An Expedient Total Synthesis of Sertraline
1997
Rhodium-Catalyzed Asymmetric Ring Opening Reactions of Oxabicyclic Alkenes: Application of Halide Effects in the Development of a General Process
2003
A Convergent Synthesis of Polysubstituted Aromatic Nitriles via Palladium-Catalyzed C−H Functionalization
2007
Effect of the substituents on the diastereoselectivity in the reduction of cyclopropyl ketones
1994
A General Modular Method of Azaindole and Thienopyrrole Synthesis via Pd-Catalyzed Tandem Couplings of gem-Dichloroolefins
2007
Chemoselectivity and stereocontrol in molybdenum-catalyzed allylic alkylations
1987
Enantioselective Catalytic Ring Expansion of Methylenecyclopropane Carboxamides Promoted by a Chiral Magnesium Lewis Acid
2007
Chlorotrimethylsilane as an Activating Reagent in the Samarium-Promoted Cyclopropanation of Allylic and α-Allenic Alcohols
1996
A New Route to Fused Aromatic Compounds by Using a Palladium-Catalyzed Alkylation – Alkenylation Sequence
2000
Synthesis of Novel Tetracycles via an Intramolecular Heck Reaction with anti-Hydride Elimination
2003
Ligand Control in Enantioselective Desymmetrization of Bicyclic Hydrazines: Rhodium(I)‐Catalyzed Ring‐Opening versus Hydroarylation
2008
Addition of Bifunctional Organoboron Reagents to Strained Alkenes. Carbon−Carbon Bond Formation with Rh(I) Catalysis in Aqueous Media
2004
A Regioselective Palladium‐Catalyzed Reduction of 3,3‐Heterobimetalated Allylic Acetates— Synthesis and Reactivity of Allylic Bimetallic Compounds
1995
Heterogeneous Palladium‐Catalyzed Regioselective Hydrostannation of Alkenes
1996
Reductive and base-induced cleavage reactions of oxabicyclic compounds
1996
Functionalized Chromans and Isochromans via a Diastereoselective Pd(0)-Catalyzed Carboiodination
2012
Palladium-Catalyzed Hydrostannation−Cyclization of 1,6-Diynes. Generation of 1,2-Dialkylidenecyclopentanes with a Tributylstannane Moiety
1997
Diastereoselectivity in the hydroxyl-directed cyclopropanation of vinylorganometallic compounds
1992
Rhodium-Catalyzed Asymmetric Ring Opening of Oxabicyclic Alkenes with Organoboronic Acids
2002
Metal–Ligand Binding Interactions in Rhodium/Palladium-Catalyzed Synthesis of Dihydroquinolines
2014
Diastereoselective Formation of Indanes from Arylboronate Esters Catalyzed by Rhodium(I) in Aqueous Media
2002
A Tandem Catalytic Approach to Methyleneindenes: Mechanistic Insights intogem-Dibromoolefin Reactivity
2010
Synthesis of Cyclohexenols and Cycloheptenols via the Regioselective Reductive Ring Opening of Oxabicyclic Compounds
1997
Scope of Palladium-Catalyzed Alkylative Ring Opening
2004
Nickel-Catalyzed Addition of Grignard Reagents to Oxabicyclic Compounds. Ring-Opening Reactions with Previously Unreactive Substrates and Nucleophiles
1996
Synthesis of 1,2-Dihydropyridines Using Vinyloxiranes as Masked Dienolates in Imino-Aldol Reactions
2006
Palladium‐Catalyzed Domino Direct Arylation/N‐Arylation: Convenient Synthesis of Phenanthridines
2009
A Route to Annulated Indoles via a Palladium-Catalyzed Tandem Alkylation/Direct Arylation Reaction
2005
An unusual dichotomy in the regioselectivity of a metal catalyzed versus thermal ene reaction
1985
Synthetic Studies of the Formation of Oxazoles and Isoxazoles from N-Acetoacetyl Derivatives: Scope and Limitations
2000
Ring Opening Reactions of Oxabicyclic Compounds as a Route to Cyclic and Acyclic Compounds with Multiple Stereocenters
1993
Rhodium-Catalyzed Asymmetric Alcoholysis and Aminolysis of Oxabenzonorbornadiene: A New Enantioselective Carbon−Heteroatom Bond Forming Process
2000
Combining Ru-Catalyzed C–H Functionalization with Pd-Catalyzed Asymmetric Allylic Alkylation: Synthesis of 3-Allyl-3-aryl Oxindole Derivatives from Aryl α-Diazoamides
2016
Modular and Stereoselective Synthesis of Tetrasubstituted Helical Alkenes via a Palladium-Catalyzed Domino Reaction
2012
Total Synthesis of Ionomycin Using Ring-Opening Strategies
2002
Tris(trimethylsilyl)aluminum and transition-metal catalysts. Silylation of allyl acetates
1983
Synthesis of Dihydronaphthalenes via Aryne Diels—Alder Reactions: Scope and Diastereoselectivity.
2006
Mild Procedure for the Catalytic Bis(stannylation) of Alkynes with Hexaalkylditins
2003
Ring opening reactions of deltacyclene epoxides
1989
Amphoteric Character of 2-Vinyloxiranes: Synthetic Equivalents ofβ,γ-Unsaturated Aldehydes and a Vinylogous Enolate
2000
Regiochemical control in the molybdenum-catalyzed reactions of trimethylsilyl- and ester-substituted allylic acetates
1983
Molybdenum catalysts for allylic alkylation
1982
Efficient Synthesis of Benzothiophenes by an Unusual Palladium‐Catalyzed Vinylic CS Coupling
2009
Regioselective Rhodium-Catalyzed Addition of Arylboronic Acids to Alkynes with a Pyridine-Substituted Water-Soluble Ligand
2001
Rhodium-Catalyzed Addition of Arylboronic Acids to Alkynyl Aza-Heteroaromatic Compounds in Water
2003
A New Route to the Enantioselective Synthesis of Cycloheptenols. Temperature Effects in the Asymmetric Reductive Ring Opening of [3.2.1] Oxabicycloalkenes
1997
Palladium-Catalyzed Carboiodination of Alkenes: Carbon−Carbon Bond Formation with Retention of Reactive Functionality
2011
A General and Practical Method of Alkynyl Indole and Benzofuran Synthesis via Tandem Cu- and Pd-Catalyzed Cross-Couplings
2007
Catalytic asymmetric induction in the homo Diels-Alder reaction
1990
Synthesis of Annulated 2H-Indazoles and 1,2,3- and 1,2,4-Triazoles via a One-Pot Palladium-Catalyzed Alkylation/Direct Arylation Reaction
2008
Rhodium(I)-Catalyzed Cyclization Reaction of o-Alkynyl Phenols and Anilines. Domino Approach to 2,3-Disubstituted Benzofurans and Indoles
2009
Preparation of cyclohexenyl derivatives by the ring-opening reactions of oxabicyclo[2.2.1] compounds with cuprates
1990
Synthesis of Dihydronaphthalenes via Aryne Diels−Alder Reactions: Scope and Diastereoselectivity
2005
Formal Synthesis of Nitidine and NK109 via Palladium-Catalyzed Domino Direct Arylation/N-Arylation of Aryl Triflates
2011
Use of a sterically demanding Lewis acid to direct ring expansion of monoactivated methylenecyclopropanes
2007
Exploiting the Divergent Reactivity of Aryl–Palladium Intermediates for the Rapid Assembly of Fluorene and Phenanthrene Derivatives
2009
Rhodium-Catalyzed Tandem Vinylcyclopropanation of Strained Alkenes
2006
A Rhodium IBiox[(−)-menthyl] Complex as a Highly Selective Catalyst for the Asymmetric Hydroarylation of Azabicyles: An Alternative Route to Epibatidine
2010
Rhodium-Catalyzed Heck-Type Coupling of Boronic Acids with Activated Alkenes in an Aqueous Emulsion
2004
Direct, One-Step Synthesis of Condensed Heterocycles: A Palladium-Catalyzed Coupling Approach
2006
A Highly Efficient and Selective Route to Isomeric Cyclic Diazadienes
2007
Efficient Syntheses of KDR Kinase Inhibitors Using a Pd-Catalyzed Tandem C−N/Suzuki Coupling as the Key Step
2007
A Palladium-Catalyzed Approach to Polycyclic Sulfur Heterocycles
2008
Total Synthesis of (+)‐Linoxepin by Utilizing the Catellani Reaction
2013
Tandem Pd-Catalyzed Double C−C Bond Formation: Effect of Water
2009
Molybdenum catalyzed eliminations of allylic acetates. new diene synthesis
1983
Ring-opening metathesis polymerization of deltacyclene via a ruthenium catalyst
1989
Asymmetric Synthesis of Bryostatin 2
1998
Ring-opening reactions of an oxabicyclic compound with cuprates
1989
Rhodium-Catalyzed Carbon−Carbon Bond Forming Reactions of Organometallic Compounds
2002
Palladium-catalyzed sequential alkylation–alkenylation reactions: application towards the synthesis of polyfunctionalized fused aromatic rings
2005
On the stereo- and regioselectivity of molybdenum-catalyzed allylic alkylations. Stereocontrolled approach to quaternary carbons and tandem alkylation-cycloaddition
1983
Total Synthesis of (−)-(α)-Kainic Acid via a Diastereoselective Methylenecyclopropane Ring Expansion
2005
Secondary Alkyl Groups in Palladium-Catalyzed Cross-Coupling Reactions
2016
Scope of the cobalt-catalyzed [2 + 2 + 2] homo-Diels-Alder reaction
1989
The Norbornene Shuttle: Multicomponent Domino Synthesis of Tetrasubstituted Helical Alkenes through Multiple CH Functionalization
2009
MgI2-Mediated Ring Expansions of Secondary Methylenecyclopropyl Amides
2003
Synthesis of Polycyclic Benzonitriles via a One-Pot Aryl Alkylation/Cyanation Reaction
2006
Palladium-Catalyzed Alkylation−Hydride Reduction Sequence: Synthesis of Meta-Substituted Arenes
2005
Modern Transition-Metal-Catalyzed Carbon–Halogen Bond Formation
2016
Palladium(II) Catalyst Systems for the Addition of Boronic Acids to Bicyclic Alkenes: New Scope and Reactivity
2003
Multicomponent Multicatalyst Reactions (MC)2R: One-Pot Synthesis of 3,4-Dihydroquinolinones
2013
Palladium-Catalyzed Sequential Alkylation−Alkenylation Reactions: New Three-Component Coupling Leading to Oxacycles
2003
Intermolecular Heck-Type Coupling of Aryl Iodides and Allylic Acetates
2005
Silacupration of oxabicyclic compounds. An interrupted ring opening reaction
1992
Sekundäre Alkylhalogenide in übergangsmetallkatalysierten Kreuzkupplungen
2009
Sequential Rhodium/Palladium Catalysis: Enantioselective Formation of Dihydroquinolinones in the Presence of Achiral and Chiral Ligands
2014
Palladium-Catalyzed Carbohalogenation: Bromide to Iodide Exchange and Domino Processes
2011
Rhodium-Catalyzed Coupling Reactions of Arylboronic Acids to Olefins in Aqueous Media
2001
Domino C–H functionalization reactions of gem-dibromoolefins: synthesis of N-fused benzo[c]carbazoles
2013
Rhodium-Catalyzed Ring Opening of Vinyl Epoxides with Alcohols and Aromatic Amines
2000