Citation Impact
Citing Papers
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
2019 StandoutScienceNobel
Farm dust and endotoxin protect against allergy through A20 induction in lung epithelial cells
2015 Science
Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein
1992 StandoutNatureNobel
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
Long-Term Engraftment and Fetal Globin Induction upon BCL11A Gene Editing in Bone-Marrow-Derived CD34 + Hematopoietic Stem and Progenitor Cells
2017
Chromosome 5 allele loss at the glucocorticoid receptor locus in human colorectal carcinomas
1988
Complex gene conversion events in germline mutation at human minisatellites
1994
The Nonobese Diabetic Mouse as a Model of Autoimmune Diabetes: Immune Dysregulation Gets the NOD
1997
Are different events involved in the development of sporadic versus hereditary tumours? The possible importance of the microenvironment in hereditary cancer
1990
A genetic map of the mouse with 4,006 simple sequence length polymorphisms
1994
A family of candidate taste receptors in human and mouse
2000 StandoutNatureNobel
Diagnosis, management, and prognosis of preschool wheeze
2014
Mammalian phosphoinositide kinases and phosphatases
2009 StandoutNobel
Asthma genetics and personalised medicine
2014
Tackling a weighty problem
1992
Adult-onset asthma: is it really different?
2013
Genetic mapping of a gene causing hypertension in the stroke-prone spontaneously hypertensive rat
1991
The secretory phospholipase A2 gene is a candidate for the Mom1 locus, a major modifier of ApcMin-induced intestinal neoplasia
1995
Molecular basis of human hypertension: Role of angiotensinogen
1992 Standout
A genetic model for colorectal tumorigenesis
1990 Standout
A comprehensive genetic map of the human genome based on 5,264 microsatellites
1996 StandoutNature
Regulatory T Cells and Immune Tolerance
2008 StandoutNobel
Identification of Cd36 (Fat) as an insulin-resistance gene causing defective fatty acid and glucose metabolism in hypertensive rats
1999
Eating disorder and epilepsy in mice lacking 5-HT2C serotonin receptors
1995 StandoutNatureNobel
Minisatellite mutation rate variation associated with a flanking DNA sequence polymorphism
1994
A Physical Map of Human Chromosome 7: An Integrated YAC Contig Map with Average STS Spacing of 79 kb
1997
Colon cancer genetics
1992
Alleles of the APC gene: An attenuated form of familial polyposis
1993
The 1993–94 Généthon human genetic linkage map
1994 Standout
The Hallmarks of Cancer
2000 Standout
Lessons from Hereditary Colorectal Cancer
1996 Standout
Distribution of tandem repeat polymorphism within minisatellite MS621 (D5S110)
1996
Molecular Diagnosis of Familial Adenomatous Polyposis
1993
Tumor suppressor genes
1991 Standout
Biology and applications of human minisatellite loci
1992
Genetic modifiers of sickle cell disease
2012
Automated construction of genetic linkage maps using an expert system (MultiMap): a human genome linkage map
1994
Allelic Loss of Chromosome 18q and Prognosis in Colorectal Cancer
1994
Asthma
2017 Standout
Innate Immunity and Asthma Risk in Amish and Hutterite Farm Children
2016 Standout
Exposure to Environmental Microorganisms and Childhood Asthma
2011 Standout
The genetics of tasting in mice VII. Glycine revisited, and the chromosomal location ofSacandSoa
1995
Chromosomal mapping of two genetic loci associated with blood-pressure regulation in hereditary hypertensive rats
1991 Nature
Close linkage of a highly polymorphic marker (D5S37) to familial adenomatous polyposis (FAP) and confirmation of FAP localization on chromosome 5q21-q22
1988
Colorectal carcinomas in mice lacking the catalytic subunit of PI(3)Kγ
2000 StandoutNatureNobel
The KRN mouse model of inflammatory arthritis
2003
DFNA5, a Gene Involved in Hearing Loss and Cancer: A Review
2012
CD36 is a sensor of diacylglycerides
2005 StandoutNatureNobel
Allele frequencies at microsatellite loci: the stepwise mutation model revisited.
1993
Arthritis Critically Dependent on Innate Immune System Players
2002
Hypoxia-Mediated Increases in l -2-hydroxyglutarate Coordinate the Metabolic Response to Reductive Stress
2015
An evaluation of genetic distances for use with microsatellite loci.
1995
High resolution of human evolutionary trees with polymorphic microsatellites
1994 StandoutNature
Phenotypic variation in colorectal adenoma/cancer expression in two families. Hereditary flat adenoma syndrome
1990
A genetic map of the mouse suitable for typing intraspecific crosses.
1992
Loss of the wild type MLH1 gene is a feature of hereditary nonpolyposis colorectal cancer
1994
Evolution of a HOXB6 intergenic region within the great apes and humans
1999
Sickle-cell disease
2010 Standout
Genomic instability occurs in colorectal carcinomas but not in adenomas
1993
Hereditary Colorectal Cancer
2003 Standout
Male–female differences in fertility and blood pressure in ACE-deficient mice
1995 StandoutNatureNobel
Asthma phenotypes: the evolution from clinical to molecular approaches
2012 Standout
Hereditary Gastrointestinal Polyposis and Nonpolyposis Syndromes
1994
The mosaic that is our genome
2003 StandoutNatureNobel
Restriction of ocular fundus lesions to a specific subgroup of APC mutations in adenomatous polyposis coli patients
1993
Genetic mapping of a second locus predisposing to hereditary non–polyposis colon cancer
1993
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
Interleukin-2 receptor γ chain mutation results in X-linked severe combined immunodeficiency in humans
1993
A method for constructing radiation hybrid maps of whole genomes
1994
Increased airway smooth muscle in preschool wheezers who have asthma at school age
2012
Rhinovirus Wheezing Illness and Genetic Risk of Childhood-Onset Asthma
2013
Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death
2016 Standout
Mismatch Repair Deficiency in Phenotypically Normal Human Cells
1995 StandoutScienceNobel
Genetic Alterations during Colorectal-Tumor Development
1988 Standout
A QTL influencing F cell production maps to a gene encoding a zinc-finger protein on chromosome 2p15
2007
Absence of linkage between the angiotensin converting enzyme locus and human essential hypertension
1992
Genetic Analysis of an Inherited Predisposition to Colon Cancer in a Family with a Variable Number of Adenomatous Polyps
1990
Genetic identification of Mom-1, a major modifier locus affecting Min-induced intestinal neoplasia in the mouse
1993
Minisatellite diversity supports a recent African origin for modern humans
1996 StandoutNobel
Cyclin A and the retinoblastoma gene product complex with a common transcription factor
1991 StandoutNatureNobel
A crucial role for macrophages in the pathology of K/B × N serum‐induced arthritis
2005
The genetics of asthma and allergic disease: a 21st century perspective
2011
European Gene Mapping Project(EUROGEM): Genetic Maps basedon the CEPH reference families
1994 Nobel
Hypermutability and mismatch repair deficiency in RER+ tumor cells
1993 StandoutNobel
Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin
2017 StandoutNature
The Early Development of Wheeze. Environmental Determinants and Genetic Susceptibility at 17q21
2015
Allelic Loss in Colorectal Carcinoma
1989
Establishment of NOD-Pdcd1-/-mice as an efficient animal model of type I diabetes
2005 StandoutNobel
Genomic structure of the human prion protein gene.
1991
Pathogenesis of asthma: implications for precision medicine
2017
Loss of constitutional heterozygosity in colorectal tumors from patients with familial polyposis coli and those with nonpolyposis colorectal carcinoma.
1989
Mutational processes of simple-sequence repeat loci in human populations.
1994
Genetic Models of Human Vascular Disease
1995 StandoutNobel
Variation of the CGG repeat at the fragile X site results in genetic instability: Resolution of the Sherman paradox
1991 Standout
Use of recombinant congenic and congenic strains of NOD mice to identify a new insulin-dependent diabetes resistance gene.
1994
Isolation of an hMSH2-p160 Heterodimer That Restores DNA Mismatch Repair to Tumor Cells
1995 StandoutScienceNobel
GENETICS OF NON-INSULIN-DEPENDENT (TYPE-II) DIABETES MELLITUS
1996
Pore-forming activity and structural autoinhibition of the gasdermin family
2016 StandoutNature
Cell Cycle Control and Cancer
1994 StandoutScienceNobel
Lung damage and airway remodelling in severe asthma
2011
Extensive Nuclear DNA Sequence Diversity Among Chimpanzees
1999 StandoutScienceNobel
Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease.
1993 Standout
Concerted Nonsyntenic Allelic Loss in Human Colorectal Carcinoma
1988 Science
Rolling replication of short DNA circles.
1995 StandoutNobel
DNA polymorphisms at the BCL11A , HBS1L-MYB , and β- globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease
2008
Mast cells contribute to initiation of autoantibody-mediated arthritis via IL-1
2007
HUMAN TUMOR SUPPRESSOR GENES
1990
New Genetic Loci That Control Susceptibility and Symptoms of Experimental Allergic Encephalomyelitis in Inbred Mice
1998
Genetic absolute dating based on microsatellites and the origin of modern humans.
1995
Genetic risk factors for the development of allergic disease identified by genome‐wide association
2014
Global Patterns of Linkage Disequilibrium at the CD4 Locus and Modern Human Origins
1996 StandoutScienceNobel
Transcriptional regulation of fetal to adult hemoglobin switching: new therapeutic opportunities
2011
Chromosome 18 allele loss at the D18S6 locus in human colorectal carcinomas
1988
Tumor Rejection After Direct Costimulation of CD8 + T Cells by B7-Transfected Melanoma Cells
1993 StandoutScienceNobel
Breakpoint analysis: precise localization of genetic markers by means of nonstatistical computation using relatively few genotypes.
1995
Extracolonic manifestations associated with familial adenomatous polyposis.
1990
daf-2 , an Insulin Receptor-Like Gene That Regulates Longevity and Diapause in Caenorhabditis elegans
1997 StandoutScienceNobel
CpG island clones from a deletion encompassing the gene for adenomatous polyposis coli.
1989
Low incidence of loss of chromosome 10 in sporadic and hereditary human medullary thyroid carcinoma.
1989
p53 gene mutations occur in combination with 17p allelic deletions as late events in colorectal tumorigenesis.
1990
Phospholipase A2Enzymes: Physical Structure, Biological Function, Disease Implication, Chemical Inhibition, and Therapeutic Intervention
2011 Standout
The Role of FcγR Signaling in the K/B × N Serum Transfer Model of Arthritis
2002
Integrating Genetic Approaches into the Discovery of Anticancer Drugs
1997 StandoutScienceNobel
Familial adenomatous polyposis
1997
YACs to the rescue
1993 StandoutNatureNobel
Evidence that the T cell repertoire of normal rats contains cells with the potential to cause diabetes. Characterization of the CD4+ T cell subset that inhibits this autoimmune potential.
1993
Interleukin 1 Receptor Dependence of Serum Transferred Arthritis Can be Circumvented by Toll-like Receptor 4 Signaling
2003
Mismatch Repair, Genetic Stability, and Cancer
1994 StandoutScienceNobel
Chromosome 17 Deletions and p53 Gene Mutations in Colorectal Carcinomas
1989 StandoutScience
Allelotype of Colorectal Carcinomas
1989 Science
Multiple Intestinal Neoplasia Caused by a Mutation in the Murine Homolog of the APC Gene
1992 Science
Complex recombination events at the hypermutable minisatellite CEB1 (D2S90).
1994
Two statistical tests for meiotic breakpoint analysis.
1995
Dimer formation by an N-terminal coiled coil in the APC protein.
1993
The Human Genome Project: Reaching the Finish Line
1998 StandoutScienceNobel
JNK1 controls mast cell degranulation and IL-1β production in inflammatory arthritis
2010 StandoutNobel
Defective Lymphoid Development in Mice Lacking Jak3
1995 StandoutScienceNobel
Targeted Therapeutic Strategies for Fetal Hemoglobin Induction
2011
Genetic instability in pancreatic cancer and poorly differentiated type of gastric cancer.
1993
Works of Mark Lathrop being referenced
Genetic analysis of autoimmune type 1 diabetes mellitus in mice
1991 Nature
A second-generation linkage map of the human genome
1992 Nature
Mutations in the gene encoding pejvakin, a newly identified protein of the afferent auditory pathway, cause DFNB59 auditory neuropathy
2006
17q21 variants modify the association between early respiratory infections and asthma
2009
A missense mutation in the glucagon receptor gene is associated with non–insulin–dependent diabetes mellitus
1995
A primary genetic map of markers for human chromosome 10
1988
Control of fetal hemoglobin: new insights emerging from genomics and clinical implications
2009
Centre d'Etude du polymorphisme humain (CEPH): Collaborative genetic mapping of the human genome
1990 Nobel
A mapped set of genetic markers for human chromosome 9
1988
The gene encoding adipose triglyceride lipase (PNPLA2) is mutated in neutral lipid storage disease with myopathy
2006
The use of synthetic tandem repeats to isolate new VNTR loci: Cloning of a human hypermutable sequence
1991
Susceptibility to insulin dependent diabetes mellitus maps to a 4.1 kb segment of DNA spanning the insulin gene and associated VNTR
1993
A Large-Scale, Consortium-Based Genomewide Association Study of Asthma
2010
Effect of 17q21 Variants and Smoking Exposure in Early-Onset Asthma
2008
Gene-environment interaction for childhood asthma and exposure to farming in Central Europe
2011
l-2-Hydroxyglutaric aciduria: identification of a mutant gene C14orf160, localized on chromosome 14q22.1
2004
A gene differentially expressed in the kidney of the spontaneously hypertensive rat cosegregates with increased blood pressure.
1993
The HBS1L-MYB intergenic interval associated with elevated HbF levels shows characteristics of a distal regulatory region in erythroid cells
2009
Intergenic variants of HBS1L-MYB are responsible for a major quantitative trait locus on chromosome 6q23 influencing fetal hemoglobin levels in adults
2007
The Gene for Familial Polyposis Coli Maps to the Long Arm of Chromosome 5
1987 Science
Genetic Influences on the End-Stage Effector Phase of Arthritis
2001
Localization of the genetic defect in familial adenomatous polyposis within a small region of chromosome 5.
1988
Polymorphisms in Type II SH2 Domain–Containing Inositol 5-Phosphatase (INPPL1, SHIP2) Are Associated With Physiological Abnormalities of the Metabolic Syndrome
2004
The HBS1L-MYB intergenic region on chromosome 6q23.3 influences erythrocyte, platelet, and monocyte counts in humans
2007
Variation in IL-1β gene expression is a major determinant of genetic differences in arthritis aggressivity in mice
2005