Citation Impact
Citing Papers
The PINK1/Parkin pathway regulates mitochondrial morphology
2008
The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila
2008
In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter
2010 StandoutNobel
Vitamin K 2 Is a Mitochondrial Electron Carrier That Rescues Pink1 Deficiency
2012 Science
Strategy for Dual-Analyte Luciferin Imaging: In Vivo Bioluminescence Detection of Hydrogen Peroxide and Caspase Activity in a Murine Model of Acute Inflammation
2013 StandoutNobel
The ubiquitin E3 ligase parkin regulates the proapoptotic function of Bax
2012
PINK1-dependent recruitment of Parkin to mitochondria in mitophagy
2009 Standout
Suppression of Reactive Oxygen Species and Neurodegeneration by the PGC-1 Transcriptional Coactivators
2006 Standout
Parkinson's disease mutations in PINK1 result in decreased Complex I activity and deficient synaptic function
2009
Genetic analysis of mitochondrial protein misfolding in Drosophila melanogaster
2012
Robust Target Gene Discovery through Transcriptome Perturbations and Genome-Wide Enhancer Predictions in Drosophila Uncovers a Regulatory Basis for Sensory Specification
2010
Oxidative modifications, mitochondrial dysfunction, and impaired protein degradation in Parkinson's disease: how neurons are lost in the Bermuda triangle
2009
Down-Regulation of Na+/K+ATPase Activity by Human Parvovirus B19 Capsid Protein VP1
2013 Standout
Genetic clues to the pathogenesis of Parkinson's disease
2004
Mitochondria take center stage in aging and neurodegeneration
2005
Parkinson disease
2017 Standout
PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
2010 Standout
Mechanism and medical implications of mammalian autophagy
2018 Standout
Parkin mitochondrial translocation is achieved through a novel catalytic activity coupled mechanism
2013
Oxidative Stress Hypothesis in Alzheimer's Disease
1997 Standout
Descending control of pain
2002 Standout
Parkin is a lipid-responsive regulator of fat uptake in mice and mutant human cells
2011
The role of autophagy in neurodegenerative disease
2013 Standout
RBR Ubiquitin Ligases: Diversification and Streamlining in Animal Lineages
2009
PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin
2010 Standout
The Roles of PINK1, Parkin, and Mitochondrial Fidelity in Parkinson’s Disease
2015 Standout
Drosophila HtrA2 is dispensable for apoptosis but acts downstream of PINK1 independently from Parkin
2009
Phosphorylation of parkin by Parkinson disease-linked kinase PINK1 activates parkin E3 ligase function and NF- B signaling
2009
SCENIC: single-cell regulatory network inference and clustering
2017 Standout
Deciphering the role of heterozygous mutations in genes associated with parkinsonism
2007
Mitochondrial fusion and fission in cell life and death
2010 Standout
Mono- and double-mutant mouse models of Parkinson's disease display severe mitochondrial damage
2007
Parkinson's disease
2009 Standout
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Mitochondria: In Sickness and in Health
2012 Standout
Dissecting muscle and neuronal disorders in a Drosophila model of muscular dystrophy
2007 StandoutNobel
Modulation of opioid antinociception by CCK at the supraspinal level: evidence of regulatory mechanisms between CCK and enkephalin systems in the control of pain
1993
Phosphorylation of Mitochondrial Polyubiquitin by PINK1 Promotes Parkin Mitochondrial Tethering
2014
Genetic and genomic studies of Drosophila parkin mutants implicate oxidative stress and innate immune responses in pathogenesis
2005
Regulation of cancer cell metabolism
2011 Standout
Parkinson's disease
2015 Standout
Ubiquitin–proteasome system and Parkinson's disease
2006
The Yeast Complex I Equivalent NADH Dehydrogenase Rescues pink1 Mutants
2012
Autophagy inhibition in cancer therapy: metabolic considerations for antitumor immunity
2012
Autophagy in Human Health and Disease
2013 Standout
MicroRNA Expression and Regulation in Human, Chimpanzee, and Macaque Brains
2011 StandoutNobel
Loss-of-Function Analysis Suggests ThatOmi/HtrA2Is Not an Essential Component of thepink1/parkinPathwayIn Vivo
2008
Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling
2012 Standout
Mechanisms of mitophagy
2010 Standout
Drosophila, the golden bug, emerges as a tool for human genetics
2005
Mutations in PINK1 and Parkin Impair Ubiquitination of Mitofusins in Human Fibroblasts
2011
100 years of Drosophila research and its impact on vertebrate neuroscience: a history lesson for the future
2010
Molecular, cellular and clinical aspects of Parvovirus B19 infection
1994
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
2006 StandoutNature
Small molecule drug screening in Drosophila identifies the 5HT2A receptor as a feeding modulation target
2013 Standout
Molecular mechanisms of necroptosis: an ordered cellular explosion
2010 Standout
Targeting autophagy in cancer
2017 Standout
An emerging role of PARK2 in cancer
2013
Mitochondrial translocation of α-synuclein is promoted by intracellular acidification
2008
The Mitochondrial Fusion-Promoting Factor Mitofusin Is a Substrate of the PINK1/Parkin Pathway
2010
Oxidative stress and neurodegeneration: where are we now?
2006 Standout
Pink1, Parkin, DJ-1 and mitochondrial dysfunction in Parkinson's disease
2007
A common LRRK2 mutation in idiopathic Parkinson's disease
2005 Standout
The PI3K Pathway in Human Disease
2017 Standout
Human Disease Models in Drosophila melanogaster and the Role of the Fly in Therapeutic Drug Discovery
2011
PINK1-Mediated Phosphorylation of Parkin Boosts Parkin Activity in Drosophila
2014
A Putative Src Homology 3 Domain Binding Motif but Not the C-terminal Dystrophin WW Domain Binding Motif Is Required for Dystroglycan Function in Cellular Polarity in Drosophila
2007 StandoutNobel
The role of parkin in familial and sporadic Parkinson's disease
2010
Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation
2009
The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
2015 StandoutNature
The amyloid state and its association with protein misfolding diseases
2014 Standout
Genetics of Parkinson's disease and parkinsonism
2006
Absence of nigral degeneration in aged parkin/DJ‐1/PINK1 triple knockout mice
2009
PARK2/Parkin-mediated mitochondrial clearance contributes to proteasome activation during slow-twitch muscle atrophy via NFE2L1 nuclear translocation
2014
Ubiquitin–proteasome system dysfunction in Parkinson’s disease: current evidence and controversies
2007
How does parkin ligate ubiquitin to Parkinson's disease?
2004
Mitochondrial Dysfunction in Genetic Animal Models of Parkinson's Disease
2011
Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling
2011 Standout
Recent Advances in the Genetics of Parkinson's Disease
2011
Native α-synuclein induces clustering of synaptic-vesicle mimics via binding to phospholipids and synaptobrevin-2/VAMP2
2013 StandoutNobel
What Genetics Tells us About the Causes and Mechanisms of Parkinson's Disease
2011
Parkin negatively regulates JNK pathway in the dopaminergic neurons ofDrosophila
2005
MicroRNA profiling of Parkinson's disease brains identifies early downregulation of miR-34b/c which modulate mitochondrial function
2011
Mitochondrial Fission, Fusion, and Stress
2012 StandoutScience
Signal transduction by reactive oxygen species
2011 Standout
Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling
2005
Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin
2006
Spermidine in health and disease
2018 StandoutScience
RING Domain E3 Ubiquitin Ligases
2009 Standout
Proteasome Inhibition Alleviates SNARE-Dependent Neurodegeneration
2012 StandoutNobel
Drosophila as a Model for Human Neurodegenerative Disease
2005
Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery
2008
Increased glutathione S -transferase activity rescues dopaminergic neuron loss in a Drosophila model of Parkinson's disease
2005
MOLECULAR PATHOPHYSIOLOGY OF PARKINSON'S DISEASE
2005
PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
2010 Standout
Nonreciprocal homeostatic compensation in Drosophila potassium channel mutants
2017 StandoutNobel
Oxidative Stress in Neurodegeneration
2011
Age-Related Reduction of Recovery Sleep and Arousal Threshold inDrosophila
2016 StandoutNobel
The Role of Atg Proteins in Autophagosome Formation
2011 StandoutNobel
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
2008 Standout
Works of Mark J. Harding being referenced
Porcine parvovirus: replication in and inhibition of selected cellular functions of swine alveolar macrophages and peripheral blood lymphocytes
1988
Differential Regulation of Simultaneous Antitumor and Alloreactive CD8+ T-Cell Responses in the Same Host by Rapamycin
2011
The effect of CCKB/gastrin antagonists on stimulated gastric acid secretion in the anaesthetized rat
1991
Two-step selection of a single R8 photoreceptor: a bistable loop betweensenselessandroughlocks in R8 fate
2008
Drosophila parkinmutants have decreased mass and cell size and increased sensitivity to oxygen radical stress
2004