Citation Impact
Citing Papers
Assembly of a Functional HCV Glycoprotein Heterodimer
2007
Partitioning of Lipid-Modified Monomeric GFPs into Membrane Microdomains of Live Cells
2002 StandoutScienceNobel
Cell culture-grown hepatitis C virus is infectious in vivo and can be recultured in vitro
2006 StandoutNobel
Reduction of Hepatitis C Virus NS5A Hyperphosphorylation by Selective Inhibition of Cellular Kinases Activates Viral RNA Replication in Cell Culture
2004
Compensatory Mutations in E1, p7, NS2, and NS3 Enhance Yields of Cell Culture-Infectious Intergenotypic Chimeric Hepatitis C Virus
2006
Neutralizing antibody response during acute and chronic hepatitis C virus infection
2004 StandoutNobel
Complete Replication of Hepatitis C Virus in Cell Culture
2005 StandoutScienceNobel
Characterization of a canine homolog of hepatitis C virus
2011 StandoutNobel
Mouse models of acute and chronic hepacivirus infection
2017 StandoutScienceNobel
NS2 Protein of Hepatitis C Virus Interacts with Structural and Non-Structural Proteins towards Virus Assembly
2011
Identification and Targeting of an Interaction between a Tyrosine Motif within Hepatitis C Virus Core Protein and AP2M1 Essential for Viral Assembly
2012
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
Hepatitis C Virus Non-structural Protein 3 (HCV NS3): A Multifunctional Antiviral Target
2010
Hepatitis C Virus NS5A Is a Direct Substrate of Casein Kinase I-α, a Cellular Kinase Identified by Inhibitor Affinity Chromatography Using Specific NS5A Hyperphosphorylation Inhibitors
2006
Computational identification of hepatitis C virus associated microRNA-mRNA regulatory modules in human livers
2009
Identification of GBV-D, a Novel GB-like Flavivirus from Old World Frugivorous Bats (Pteropus giganteus) in Bangladesh
2010
Assembly of infectious hepatitis C virus particles
2010
Hepatitis C Virus p7 membrane protein quasispecies variability in chronically infected patients treated with interferon and ribavirin, with or without amantadine
2006
SEC14L2 enables pan-genotype HCV replication in cell culture
2015 StandoutNatureNobel
Hepatitis C Virus NS5A Protein Is a Substrate for the Peptidyl-prolyl cis/trans Isomerase Activity of Cyclophilins A and B
2009
Completion of the entire hepatitis C virus life cycle in genetically humanized mice
2013 StandoutNatureNobel
Animal Models for the Study of Hepatitis C Virus Infection and Related Liver Disease
2012
Hepatitis C Virus Non-structural Proteins in the Probable Membranous Compartment Function in Viral Genome Replication
2003
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
Hepatitis C virus—host interactions, replication, and viral assembly
2012
Molecular Determinants and Dynamics of Hepatitis C Virus Secretion
2012
Viral targets of acylguanidines
2012
Unravelling hepatitis C virus replication from genome to function
2005 StandoutNatureNobel
Hepatitis C Virus p7 is Critical for Capsid Assembly and Envelopment
2013
Architects of assembly: roles of Flaviviridae non-structural proteins in virion morphogenesis
2008 StandoutNobel
Surveying the global virome: Identification and characterization of HCV-related animal hepaciviruses
2014
Raf‐1 kinase associates with Hepatitis C virus NS5A and regulates viral replication
2005
Evasion of intracellular host defence by hepatitis C virus
2005 Nature
Fatty acylation of proteins: new insights into membrane targeting of myristoylated and palmitoylated proteins
1999
Essential Role of Cyclophilin A for Hepatitis C Virus Replication and Virus Production and Possible Link to Polyprotein Cleavage Kinetics
2009
Liver Injury and Disease Pathogenesis in Chronic Hepatitis C
2013
Hepatitis C viral protein translation: mechanisms and implications in developing antivirals
2011
The Nonstructural 5A Protein of Hepatitis C Virus Genotype 1b Does Not Contain an Interferon Sensitivity–Determining Region
2007
Hepatitis C Virus RNA Replication
2013
Viroporins
2003
A novel Hepatitis C virus p7 ion channel inhibitor, BIT225, inhibits bovine viral diarrhea virus in vitro and shows synergism with recombinant interferon-α-2b and nucleoside analogues
2010
Hepatitis C Virus Proteins: From Structure to Function
2013
Structural and Functional Characterization of Nonstructural Protein 2 for Its Role in Hepatitis C Virus Assembly
2008
Viral channel proteins in intracellular protein–protein communication: Vpu of HIV-1, E5 of HPV16 and p7 of HCV
2013
Differential effect of p7 inhibitors on hepatitis C virus cell-to-cell transmission
2013
Screening of the Pan-African Natural Product Library Identifies Ixoratannin A-2 and Boldine as Novel HIV-1 Inhibitors
2015 StandoutNobel
Hepatitis C Virus p7 Protein Is Crucial for Assembly and Release of Infectious Virions
2007
The ESCRT System Is Required for Hepatitis C Virus Production
2011
Prospects for a vaccine against the hepatitis C virus
2005 StandoutNatureNobel
Cation‐selective ion channels formed by p7 of hepatitis C virus are blocked by hexamethylene amiloride
2003
Chapter 2 Cutting the Gordian Knot-Development and Biological Relevance of Hepatitis C Virus Cell Culture Systems
2008
Hepatitis C virus ultrastructure and morphogenesis
2004
A Major Determinant of Cyclophilin Dependence and Cyclosporine Susceptibility of Hepatitis C Virus Identified by a Genetic Approach
2010
Biochemical and Morphological Properties of Hepatitis C Virus Particles and Determination of Their Lipidome
2010
The human T-cell leukemia virus type 1 p13II protein: effects on mitochondrial function and cell growth
2005
The ins and outs of hepatitis C virus entry and assembly
2013 StandoutNobel
A Membrane-proximal Basic Domain and Cysteine Cluster in the C-terminal Tail of CCR5 Constitute a Bipartite Motif Critical for Cell Surface Expression
2001 StandoutNobel
Regulation of Hepatitis C Virion Production via Phosphorylation of the NS5A Protein
2008
Regulation of Hepatitis C Virus Polyprotein Processing by Signal Peptidase Involves Structural Determinants at the p7 Sequence Junctions
2004
Function Follows Form: The Structure of the N-Terminal Domain of HCV NS5A *
2005
Modulation of HIV-1 replication by RNA interference
2002 Nature
The role of the CXC chemokines platelet factor-4 (CXCL4/PF-4) and its variant (CXCL4L1/PF-4var) in inflammation, angiogenesis and cancer
2010
Regulation of hepatitis C virus secretion by the Hrs-dependent exosomal pathway
2011
Mitochondrial Membrane Permeabilization in Cell Death
2007 Standout
Insights into RNA Biology from an Atlas of Mammalian mRNA-Binding Proteins
2012 Standout
NS5A inhibitors in the treatment of hepatitis C
2013
Claudin-1 is a hepatitis C virus co-receptor required for a late step in entry
2007 StandoutNatureNobel
A diverse range of gene products are effectors of the type I interferon antiviral response
2011 StandoutNatureNobel
Hepatitis C Virus-Specific Directly Acting Antiviral Drugs
2013
Hepatitis C virus RNA replication is regulated by FKBP8 and Hsp90
2006
Analysis of Functional Differences between Hepatitis C Virus NS5A of Genotypes 1–7 in Infectious Cell Culture Systems
2012
Development and characterization of hepatitis C virus genotype 1-7 cell culture systems: Role of CD81 and scavenger receptor class B type I and effect of antiviral drugs # †
2008
Phosphorylation of hepatitis C virus NS5A nonstructural protein: A new paradigm for phosphorylation-dependent viral RNA replication?
2007
Antiviral effects of amantadine and iminosugar derivatives against hepatitis C virus†
2007
Virion Assembly and Release
2013
Metabolism of Phosphatidylinositol 4-Kinase IIIα-Dependent PI4P Is Subverted by HCV and Is Targeted by a 4-Anilino Quinazoline with Antiviral Activity
2012
Structural biology of hepatitis C virus
2004
Preferential replication of HIV-1 in the CD45RO memory cell subset of primary CD4 lymphocytes in vitro.
1997
Structure of the zinc-binding domain of an essential component of the hepatitis C virus replicase
2005 StandoutNatureNobel
Animal Models for Hepatitis C
2013
The HCV Life Cycle: In vitro Tissue Culture Systems and Therapeutic Targets
2014 Standout
Unusual architecture of the p7 channel from hepatitis C virus
2013 Nature
Understanding the hepatitis C virus life cycle paves the way for highly effective therapies
2013 StandoutNobel
Signal Peptide Peptidase-catalyzed Cleavage of Hepatitis C Virus Core Protein Is Dispensable for Virus Budding but Destabilizes the Viral Capsid
2006
The NS5A Protein of Hepatitis C Virus Is a Zinc Metalloprotein
2004 StandoutNobel
A genetically humanized mouse model for hepatitis C virus infection
2011 StandoutNatureNobel
A Concerted Action of Hepatitis C Virus P7 and Nonstructural Protein 2 Regulates Core Localization at the Endoplasmic Reticulum and Virus Assembly
2011
Recombinant HCV Variants With NS5A From Genotypes 1–7 Have Different Sensitivities to an NS5A Inhibitor but Not Interferon-α
2010
Novel Insights into Hepatitis C Virus Replication and Persistence
2004
The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
2015 StandoutNature
Innate Immune Responses to Hepatitis C Virus
2013 StandoutNobel
TMEM41B Is a Pan-flavivirus Host Factor
2020 StandoutNobel
Structural and Functional Studies of Nonstructural Protein 2 of the Hepatitis C Virus Reveal Its Key Role as Organizer of Virion Assembly
2010
Essential Role of Domain III of Nonstructural Protein 5A for Hepatitis C Virus Infectious Particle Assembly
2008
Small RNAs are modified with N-glycans and displayed on the surface of living cells
2021 StandoutNobel
Pathophysiology of hepatitis C virus infection and related liver disease
2004
Adenosine Monophosphate-Activated Protein Kinase: A Central Regulator of Metabolism with Roles in Diabetes, Cancer, and Viral Infection
2011
Replication of hepatitis C virus
2007 StandoutNobel
Hepatitis C Virus RNA Functionally Sequesters miR-122
2015 StandoutNobel
Quantitative Analysis of the Hepatitis C Virus Replication Complex
2005
Regulation of the Production of Infectious Genotype 1a Hepatitis C Virus by NS5A Domain III
2011
The 3-dimensional structure of a hepatitis C virus p7 ion channel by electron microscopy
2009
Phosphoinositides in the Hepatitis C Virus Life Cycle
2012
Hepatitis C virus glycoproteins mediate pH-dependent cell entry of pseudotyped retroviral particles
2003 StandoutNobel
A Novel Hepacivirus with an Unusually Long and Intrinsically Disordered NS5A Protein in a Wild Old World Primate
2013
Hepatitis C Virus Egress and Release Depend on Endosomal Trafficking of Core Protein
2010
Identification of a previously undescribed divergent virus from the Flaviviridae family in an outbreak of equine serum hepatitis
2013
Quantification of CD4, CCR5, and CXCR4 levels on lymphocyte subsets, dendritic cells, and differentially conditioned monocyte-derived macrophages
1999 StandoutNobel
Hallmarks of Hepatitis C Virus in Equine Hepacivirus
2014
NMR Structure and Molecular Dynamics of the In-Plane Membrane Anchor of Nonstructural Protein 5A from Bovine Viral Diarrhea Virus,
2006
Human VAP-B Is Involved in Hepatitis C Virus Replication through Interaction with NS5A and NS5B
2005
Analysis of the processing and transmembrane topology of the E2p7 protein of hepatitis C virus
2005
Inhibition of RIG-I-Dependent Signaling to the Interferon Pathway during Hepatitis C Virus Expression and Restoration of Signaling by IKKε
2005
Protein−Protein Interactions: Modeling the Hepatitis C Virus Ion Channel p7
2005
Resistance Analysis of the Hepatitis C Virus NS5A Inhibitor BMS-790052 in an In Vitro Replicon System
2010
Viral evasion and subversion of pattern-recognition receptor signalling
2008
Ultrastructural analysis of hepatitis C virus particles
2013 StandoutNobel
Characterization of nonprimate hepacivirus and construction of a functional molecular clone
2015 StandoutNobel
Human broadly neutralizing antibodies to the envelope glycoprotein complex of hepatitis C virus
2012 StandoutNobel
Cell Culture Adaptation of Hepatitis C Virus and In Vivo Viability of an Adapted Variant
2007
Protein Kinase A-Dependent Step(s) in Hepatitis C Virus Entry and Infectivity
2008
Antiviral Stilbene 1,2-Diamines Prevent Initiation of Hepatitis C Virus RNA Replication at the Outset of Infection
2011 StandoutNobel
Disrupting the association of hepatitis C virus core protein with lipid droplets correlates with a loss in production of infectious virus
2007
Transdominant Inhibition of Bovine Viral Diarrhea Virus Entry
2007 StandoutNobel
Hepatitis C Virus NS2 Protein Serves as a Scaffold for Virus Assembly by Interacting with both Structural and Nonstructural Proteins
2010
Seed Sequence-Matched Controls Reveal Limitations of Small Interfering RNA Knockdown in Functional and Structural Studies of Hepatitis C Virus NS5A-MOBKL1B Interaction
2014 StandoutNobel
Modeling shows that the NS5A inhibitor daclatasvir has two modes of action and yields a shorter estimate of the hepatitis C virus half-life
2013
Studying Hepatitis C Virus: Making the Best of a Bad Virus
2007 StandoutNobel
The hepatitis C virus p7 protein forms an ion channel that is inhibited by long-alkyl-chain iminosugar derivatives
2003
Characterization of Infectious Retroviral Pseudotype Particles Bearing Hepatitis C Virus Glycoproteins
2004 StandoutNobel
Genetic diversity and evolution of hepatitis C virus – 15 years on
2004
Hepatitis C Virus p7 and NS2 Proteins Are Essential for Production of Infectious Virus
2007 StandoutNobel
Identification of Residues Required for RNA Replication in Domains II and III of the Hepatitis C Virus NS5A Protein
2007 StandoutNobel
Ribavirin Resistance in Hepatitis C Virus Replicon-Containing Cell Lines Conferred by Changes in the Cell Line or Mutations in the Replicon RNA
2005
Fast Hepatitis C Virus RNA Elimination and NS5A Redistribution by NS5A Inhibitors Studied by a Multiplex Assay Approach
2015 StandoutNobel
The α Isoform of Protein Kinase CKI Is Responsible for Hepatitis C Virus NS5A Hyperphosphorylation
2006
Regulation of Hepatitis C Virus Replication by Nuclear Translocation of Nonstructural 5A Protein and Transcriptional Activation of Host Genes
2013
Amino Acid Variations in Hepatitis C Virus P7 and Sensitivity to Antiviral Combination Therapy with Amantadine in Chronic Hepatitis C
2006
Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus
2006 StandoutNobel
Cellular cofactors affecting hepatitis C virus infection and replication
2007 StandoutNobel
On the History of Hepatitis C Virus Cell Culture Systems
2013
Mitochondria as Functional Targets of Proteins Coded by Human Tumor Viruses
2005
Clearance of replicating hepatitis C virus replicon RNAs in cell culture by small interfering RNAs
2002 StandoutNobel
Characterization of the Early Steps of Hepatitis C Virus Infection by Using Luciferase Reporter Viruses
2006
Robust Production of Infectious Hepatitis C Virus (HCV) from Stably HCV cDNA-Transfected Human Hepatoma Cells
2005
Activation of naïve B lymphocytes via CD81, a pathogenetic mechanism for hepatitis C virus-associated B lymphocyte disorders
2005 StandoutNobel
The p7 polypeptide of hepatitis C virus is critical for infectivity and contains functionally important genotype-specific sequences
2003
Genetic and Functional Characterization of the N-Terminal Region of the Hepatitis C Virus NS2 Protein
2013 StandoutNobel
The Multifaceted Roles of Autophagy in Flavivirus-Host Interactions
2018
The Hepatitis C Virus NS4B Protein Can trans -Complement Viral RNA Replication and Modulates Production of Infectious Virus
2008
Alanine Scanning of the Hepatitis C Virus Core Protein Reveals Numerous Residues Essential for Production of Infectious Virus
2007 StandoutNobel
NS3 Helicase Domains Involved in Infectious Intracellular Hepatitis C Virus Particle Assembly
2008
Ultrastructural and Biophysical Characterization of Hepatitis C Virus Particles Produced in Cell Culture
2010
Domain 2 of Nonstructural Protein 5A (NS5A) of Hepatitis C Virus Is Natively Unfolded
2007
Differential Biophysical Properties of Infectious Intracellular and Secreted Hepatitis C Virus Particles
2006
Structure of the catalytic domain of the hepatitis C virus NS2-3 protease
2006 StandoutNatureNobel
Works of Mark Harris being referenced
Resistance mutations define specific antiviral effects for inhibitors of the hepatitis C virus p7 ion channel
2011
Evidence for the Formation of a Heptameric Ion Channel Complex by the Hepatitis C Virus P7 Protein in Vitro
2006
Intracellular Proton Conductance of the Hepatitis C Virus p7 Protein and Its Contribution to Infectious Virus Production
2010
Physical and Functional Interaction of Nef with Lck
1996
Vps4 and the ESCRT-III complex are required for the release of infectious hepatitis C virus particles
2009
The p7 protein of hepatitis C virus forms an ion channel that is blocked by the antiviral drug, Amantadine
2002
The Hepatitis C Virus Non-structural NS5A Protein Inhibits Activating Protein–1 Function by Perturbing Ras-ERK Pathway Signaling
2003
Genotype-dependent sensitivity of hepatitis C virus to inhibitors of the p7 ion channel
2008
Inhibition of hepatitis C virus p7 membrane channels in a liposome-based assay system
2007
Optineurin Negatively Regulates the Induction of IFNβ in Response to RNA Virus Infection
2010
Chimeric GB virus B genomes containing hepatitis C virus p7 are infectious in vivo
2008
Hepatitis C virus NS5A protein interacts with -catenin and stimulates its transcriptional activity in a phosphoinositide-3 kinase-dependent fashion
2009
The subcellular localization of the hepatitis C virus non-structural protein NS2 is regulated by an ion channel-independent function of the p7 protein
2010
The Hepatitis C Virus NS5A Protein Activates a Phosphoinositide 3-Kinase-dependent Survival Signaling Cascade
2004
Hepatitis C Virus-Induced Autophagy Is Independent of the Unfolded Protein Response
2012
Effect of heparin on the in vivo release and clearance of human platelet factor 4
1983
Tagging of NS5A expressed from a functional hepatitis C virus replicon
2006
Perturbation of epidermal growth factor receptor complex formation and Ras signalling in cells harbouring the hepatitis C virus subgenomic replicon
2005
Enhanced hepatitis C virus genome replication and lipid accumulation mediated by inhibition of AMP-activated protein kinase
2010
The inhibition of cAMP-dependent protein kinase by full-length hepatitis C virus NS3/4A complex is due to ATP hydrolysis
2001
Signal Peptide Cleavage and Internal Targeting Signals Direct the Hepatitis C Virus p7 Protein to Distinct Intracellular Membranes
2005
The hepatitis C virus NS5A protein binds to members of the Src family of tyrosine kinases and regulates kinase activity
2004
The non-primate hepacivirus 5′ untranslated region possesses internal ribosomal entry site activity
2013
A conserved basic loop in hepatitis C virus p7 protein is required for amantadine-sensitive ion channel activity in mammalian cells but is dispensable for localization to mitochondria
2004
Introduction of replication-competent hepatitis C virus transcripts using a tetracycline-regulable baculovirus delivery system
2004
Characterisation of the Role of Zinc in the Hepatitis C Virus NS2/3 Auto-cleavage and NS3 Protease Activities
2006
Virion Incorporation of Human Immunodeficiency Virus Type 1 Nef Is Mediated by a Bipartite Membrane-Targeting Signal: Analysis of Its Role in Enhancement of Viral Infectivity
1998
A link between translation of the hepatitis C virus polyprotein and polymerase function; possible consequences for hyperphosphorylation of NS5A
2005
Hepatitis C Virus NS5A-Mediated Activation of Phosphoinositide 3-Kinase Results in Stabilization of Cellular β-Catenin and Stimulation of β-Catenin-Responsive Transcription
2005
Domain III of NS5A contributes to both RNA replication and assembly of hepatitis C virus particles
2009
High-Risk Human Papillomavirus E5 Oncoprotein Displays Channel-Forming Activity Sensitive to Small-Molecule Inhibitors
2012
Hepatitis C virus NS5A: tales of a promiscuous protein
2004
Determinants of Hepatitis C Virus p7 Ion Channel Function and Drug Sensitivity Identified In Vitro
2009
All Three Domains of the Hepatitis C Virus Nonstructural NS5A Protein Contribute to RNA Binding
2010
Cyclophilin A Interacts with Domain II of Hepatitis C Virus NS5A and Stimulates RNA Binding in an Isomerase-Dependent Manner
2011
Further studies on hepatitis C virus NS5A–SH3 domain interactions: identification of residues critical for binding and implications for viral RNA replication and modulation of cell signalling
2005
A Conserved Proline between Domains II and III of Hepatitis C Virus NS5A Influences both RNA Replication and Virus Assembly
2009