Citation Impact
Citing Papers
TRP channel activation by reversible covalent modification
2006 StandoutNobel
A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein
2007 StandoutNobel
Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels
2010 StandoutScienceNobel
A Modular PIP 2 Binding Site as a Determinant of Capsaicin Receptor Sensitivity
2003 StandoutScienceNobel
Structure of the human TRPM4 ion channel in a lipid nanodisc
2017 StandoutScienceNobel
4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1
2007 StandoutNobel
Gain-of-function Na v 1.8 mutations in painful neuropathy
2012
The trp ion channel family
2001
ANKTM1, a TRP-like Channel Expressed in Nociceptive Neurons, Is Activated by Cold Temperatures
2003 StandoutNobel
Formation of Novel TRPC Channels by Complex Subunit Interactions in Embryonic Brain
2003
Endogenously Expressed Trp1 Is Involved in Store-mediated Ca2+ Entry by Conformational Coupling in Human Platelets
2002
Activation of Store-Operated Ca2+ Current in Xenopus Oocytes Requires SNAP-25 but Not a Diffusible Messenger
1999 StandoutNobel
Structure of the TRPA1 ion channel suggests regulatory mechanisms
2015 StandoutNatureNobel
International Union of Pharmacology. XLIX. Nomenclature and Structure-Function Relationships of Transient Receptor Potential Channels
2005 StandoutNobel
A Diacylglycerol-Gated Cation Channel in Vomeronasal Neuron Dendrites Is Impaired in TRPC2 Mutant Mice
2003
Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines
2007 StandoutNatureNobel
Regulation of TRP Ion Channels by Phosphatidylinositol-4,5-Bisphosphate
2007
Multiple regulation by calcium of murine homologues of transient receptor potential proteins TRPC6 and TRPC7 expressed in HEK293 cells
2004
Molecular mechanisms of nociception
2001 StandoutNatureNobel
Coassembly of Trp1 and Trp3 Proteins Generates Diacylglycerol- and Ca2+-sensitive Cation Channels
2000
Sensitization of TRPA1 by PAR2 contributes to the sensation of inflammatory pain
2007
Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain
2016 StandoutNatureNobel
TRP channels and lipids: from Drosophila to mammalian physiology
2006
Cryopyrin activates the inflammasome in response to toxins and ATP
2006 StandoutNature
Increased inwardly rectifying potassium currents in HEK-293 cells expressing murine transient receptor potential 4
2001
Calcium Absorption Across Epithelia
2004
Irritant-evoked activation and calcium modulation of the TRPA1 receptor
2020 StandoutNatureNobel
In Vivo Light-induced and Basal Phospholipase C Activity in Drosophila Photoreceptors Measured with Genetically Targeted Phosphatidylinositol 4,5-Bisphosphate-sensitive Ion Channels (Kir2.1)
2004
A Neanderthal Sodium Channel Increases Pain Sensitivity in Present-Day Humans
2020 StandoutNobel
Characteristics of P2X7 receptors from human B lymphocytes expressed in Xenopus oocytes
2000
Signal-dependent Hydrolysis of Phosphatidylinositol 4,5-Bisphosphate without Activation of Phospholipase C
2011
The NaV1.7 sodium channel: from molecule to man
2012
Integration of Phosphoinositide- and Calmodulin-Mediated Regulation of TRPC6
2007
A Bivalent Tarantula Toxin Activates the Capsaicin Receptor, TRPV1, by Targeting the Outer Pore Domain
2010 StandoutNobel
The Role of Endogenous Human Trp4 in Regulating Carbachol-induced Calcium Oscillations in HEK-293 Cells
2002
Phosphoinositide Sensitivity of Ion Channels, a Functional Perspective
2012
Phosphoinositide Regulation of TRP Channels
2014
A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain
2011 StandoutNatureNobel
Store-Operated Calcium Channels
2005 Standout
Ganglion-specific splicing of TRPV1 underlies infrared sensation in vampire bats
2011 StandoutNatureNobel
The Transmembrane Segment S6 Determines Cation versus Anion Selectivity of TRPM2 and TRPM8
2007
Drosophila visual transduction
2012
A Cell-Penetrating Scorpion Toxin Enables Mode-Specific Modulation of TRPA1 and Pain
2019 StandoutNobel
TRPV1 structures in distinct conformations reveal activation mechanisms
2013 StandoutNatureNobel
Molecular basis of infrared detection by snakes
2010 StandoutNatureNobel
Exocytotic Insertion of TRPC6 Channel into the Plasma Membrane upon Gq Protein-coupled Receptor Activation
2004
PI(4,5)P2 regulates the activation and desensitization of TRPM8 channels through the TRP domain
2005
Inhibition of native TRPC6 channel activity by phosphatidylinositol 4,5‐bisphosphate in mesenteric artery myocytes
2008
Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition
2001 StandoutNatureNobel
Painful peripheral neuropathy and sodium channel mutations
2014
Structure of the TRPV1 ion channel determined by electron cryo-microscopy
2013 StandoutNatureNobel
Identification of a cold receptor reveals a general role for TRP channels in thermosensation
2002 StandoutNatureNobel
Regulation of transient receptor potential (TRP) channels by phosphoinositides
2007
Chapter 4 Genetics and Molecular Pathophysiology of Nav1.7‐Related Pain Syndromes
2008
Phosphoinositide regulation of TRPV1 revisited
2015
SCN9A Variants May be Implicated in Neuropathic Pain Associated With Diabetic Peripheral Neuropathy and Pain Severity
2015
TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action
2016 StandoutNatureNobel
A TRP Channel that Senses Cold Stimuli and Menthol
2002 StandoutNobel
The major genetic risk factor for severe COVID-19 is inherited from Neanderthals
2020 StandoutNatureNobel
Structural snapshots of TRPV1 reveal mechanism of polymodal functionality
2021 StandoutNobel
A-740003 [N-(1-{[(Cyanoimino)(5-quinolinylamino) methyl]amino}-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide], a Novel and Selective P2X7 Receptor Antagonist, Dose-Dependently Reduces Neuropathic Pain in the Rat
2006
Cellular and Molecular Mechanisms of Pain
2009 StandoutNobel
Capacitative calcium entry channels
1999
SWELL1, a Plasma Membrane Protein, Is an Essential Component of Volume-Regulated Anion Channel
2014 StandoutNobel
Noxious Cold Ion Channel TRPA1 Is Activated by Pungent Compounds and Bradykinin
2004 StandoutNobel
Molecular Basis for Species-Specific Sensitivity to “Hot” Chili Peppers
2002 StandoutNobel
The menthol receptor TRPM8 is the principal detector of environmental cold
2007 StandoutNatureNobel
Regulation of Drosophila TRPC channels by lipid messengers
2009
Visual transduction in Drosophila
2001 Nature
TRP channels in Drosophila photoreceptors: the lipid connection
2003
Spider toxins activate the capsaicin receptor to produce inflammatory pain
2006 StandoutNatureNobel
TRPA1 Mediates the Inflammatory Actions of Environmental Irritants and Proalgesic Agents
2006 StandoutNobel
Patterns of activity-dependent conduction velocity changes differentiate classes of unmyelinated mechano-insensitive afferents including cold nociceptors, in pig and in human
2009
Transfection of rat or mouse neurons by biolistics or electroporation
2009
Transient receptor potential channels as molecular substrates of receptor-mediated cation entry
1999
Activation of TRP Channels by Protons and Phosphoinositide Depletion in Drosophila Photoreceptors
2010
Trp1, a Candidate Protein for the Store-operated Ca2+Influx Mechanism in Salivary Gland Cells
2000
LRRC8 Proteins Form Volume-Regulated Anion Channels that Sense Ionic Strength
2016 StandoutNobel
Nociceptors: the sensors of the pain pathway
2010 StandoutNobel
TRP channels in Drosophila photoreceptor cells
2005
Volume expansion-sensing outward-rectifier Cl- channel: fresh start to the molecular identity and volume sensor
1997
TRP Channel Proteins and Signal Transduction
2002
Molecular Physiology of P2X Receptors
2002 Standout
TRPC5 as a candidate for the nonselective cation channel activated by muscarinic stimulation in murine stomach
2003
The Complex and Intriguing Lives of PIP2 with Ion Channels and Transporters
2001
Maitotoxin and P2Z/P2X7purinergic receptor stimulation activate a common cytolytic pore
1999
Activation of Trp3 by inositol 1,4,5-trisphosphate receptors through displacement of inhibitory calmodulin from a common binding domain
2001
Regulation of TRP Channels via Lipid Second Messengers
2003
The TRP Superfamily of Cation Channels
2005
Sodium Channels in Normal and Pathological Pain
2010
Receptor-activated Ca2+ inflow in animal cells: a variety of pathways tailored to meet different intracellular Ca2+ signalling requirements
1999
Regulation of P2X7 nucleotide receptor function in human monocytes by extracellular ions and receptor density
2001
Pungent products from garlic activate the sensory ion channel TRPA1
2005 StandoutNobel
TRPV1 Channels Are Intrinsically Heat Sensitive and Negatively Regulated by Phosphoinositide Lipids
2013 StandoutNobel
TRP Channels and Pain
2013 StandoutNobel
The Complex and Intriguing Lives of PIP 2 with Ion Channels and Transporters
2001
Physiology, Phylogeny, and Functions of the TRP Superfamily of Cation Channels
2001
Impaired Thermosensation in Mice Lacking TRPV3, a Heat and Camphor Sensor in the Skin
2005 StandoutScienceNobel
Physiology, Phylogeny, and Functions of the TRP Superfamily of Cation Channels
2001
TRPC6 is a candidate channel involved in receptor-stimulated cation currents in A7r5 smooth muscle cells
2002
Three Peptide Modulators of the Human Voltage-Gated Sodium Channel 1.7, an Important Analgesic Target, from the Venom of an Australian Tarantula
2015
AN INTRODUCTION TO TRP CHANNELS
2005 Standout
Nav1.1 Modulation by a Novel Triazole Compound Attenuates Epileptic Seizures in Rodents
2014
INSIGHTS ON TRP CHANNELS FROM IN VIVO STUDIES IN DROSOPHILA
2005
Coupling between inositol 1,4,5-trisphosphate receptors and human transient receptor potential channel 1 when intracellular Ca2+ stores are depleted
2000
Receptors for Purines and Pyrimidines
2012 Standout
Rufinamide Attenuates Mechanical Allodynia in a Model of Neuropathic Pain in the Mouse and Stabilizes Voltage-gated Sodium Channel Inactivated State
2012
A Heat-Sensitive TRP Channel Expressed in Keratinocytes
2002 StandoutScienceNobel
Unconventional Secretion, Unconventional Solutions
2013 StandoutScienceNobel
Inhibition of endogenous TRP1 decreases capacitative Ca2+entry and attenuates pulmonary artery smooth muscle cell proliferation
2002
TRP Channels
2007 Standout
Structural insights into TRPM8 inhibition and desensitization
2019 StandoutScienceNobel
Host nutritional selenium status as a driving force for influenza virus mutations
2001
Evidence that Ca2+-release-activated Ca2+ channels in rat hepatocytes are required for the maintenance of hormone-induced Ca2+ oscillations
2003
Expression and role of TRPC proteins in human platelets: evidence that TRPC6 forms the store-independent calcium entry channel
2002
Works of Mark Estación being referenced
Maitotoxin induces biphasic interleukin-1beta secretion and membrane blebbing in murine macrophages.
2004
Gain of function Na V 1.7 mutations in idiopathic small fiber neuropathy
2011
NaV1.7 Gain-of-function Mutations As A Continuum: A1632E Displays Physiological Changes Associated With Erythromelalgia And Paroxysmal Extreme Pain Disorder Mutations And Produces Symptoms Of Both Disorders
2009
Voltage-clamp and current-clamp recordings from mammalian DRG neurons
2009
Regulation of Drosophila TRPL Channels by Immunophilin FKBP59
2001
Association of Immunophilins with Mammalian TRPC Channels
2004
A novel Nav1.7 mutation producing carbamazepine‐responsive erythromelalgia
2009
Regulation of Drosophila transient receptor potential‐like (TrpL) channels by phospholipase C‐dependent mechanisms
2001
Structural modelling and mutant cycle analysis predict pharmacoresponsiveness of a Nav1.7 mutant channel
2012
Gain-of-function mutations in sodium channel NaV1.9 in painful neuropathy
2014
NaV1.7 Gain-of-Function Mutations as a Continuum: A1632E Displays Physiological Changes Associated with Erythromelalgia and Paroxysmal Extreme Pain Disorder Mutations and Produces Symptoms of Both Disorders
2008
A sodium channel gene SCN9A polymorphism that increases nociceptor excitability
2009
Human TRPC6 expressed in HEK 293 cells forms non‐selective cation channels with limited Ca2+ permeability
2006
Activation of Human TRPC6 Channels by Receptor Stimulation
2004
A sodium channel mutation linked to epilepsy increases ramp and persistent current of Nav1.3 and induces hyperexcitability in hippocampal neurons
2010
Differential effect of D623N variant and wild-type Nav1.7 sodium channels on resting potential and interspike membrane potential of dorsal root ganglion neurons
2013
Paroxysmal Extreme Pain Disorder M1627K Mutation in Human Nav1.7 Renders DRG Neurons Hyperexcitable
2008
Stimulation of Drosophila TrpL by capacitative Ca2+ entry
1999
Characterization of ion channels seen in subconfluent human dermal fibroblasts.
1991
P2X7 Receptor-Dependent Blebbing and the Activation of Rho-Effector Kinases, Caspases, and IL-1β Release
2003
Maitotoxin activates a nonselective cation channel and a P2Z/P2X7-like cytolytic pore in human skin fibroblasts
1999
Intra- and Interfamily Phenotypic Diversity in Pain Syndromes Associated with a Gain-of-Function Variant of NaV1.7
2011
Stimulation of Drosophila TrpL by capacitative Ca2+ entry
1999
Functional expression of TrpC1: a human homologue of the Drosophila Trp channel
1998
Maitotoxin Induces Biphasic Interleukin-1β Secretion and Membrane Blebbing in Murine Macrophages
2004