Citation Impact
Citing Papers
TRP channel activation by reversible covalent modification
2006 StandoutNobel
2010 ACCF/AHA/AATS/ACR/ASA/SCA/SCAI/SIR/STS/SVM Guidelines for the Diagnosis and Management of Patients With Thoracic Aortic Disease
2010 Standout
Activating Mutations of NOTCH1 in Human T Cell Acute Lymphoblastic Leukemia
2004 StandoutScience
Ent3p and Ent5p Exhibit Cargo-specific Functions in Trafficking Proteins between the Trans -Golgi Network and the Endosomes in Yeast
2007 StandoutNobel
Cooperative assembly of higher-order Notch complexes functions as a switch to induce transcription
2007
Topological control of cytokine receptor signaling induces differential effects in hematopoiesis
2019 StandoutScienceNobel
Identification and proteomic profiling of exosomes in human urine
2004 Standout
An experimentally determined protein folding energy landscape
2004
Role of the Endocytic Machinery in the Sorting of Lysosome-associated Membrane Proteins
2005
The EGLN-HIF O 2 -Sensing System: Multiple Inputs and Feedbacks
2017 StandoutNobel
Engineered receptors for soluble cellular communication and disease sensing
2024 StandoutNatureNobel
Synergistic enhancement of cellulase pairs linked by consensus ankyrin repeats: Determination of the roles of spacing, orientation, and enzyme identity
2016
Calorimetric study of a series of designed repeat proteins: Modular structure and modular folding
2010
Potent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine Brain
2015 StandoutNobel
Folding and Unfolding Mechanism of Highly Stable Full-Consensus Ankyrin Repeat Proteins
2007
Sorting in the endosomal system in yeast and animal cells
2000
Target Selectivity of Vertebrate Notch Proteins
2005
The ankyrin repeat as molecular architecture for protein recognition
2004
Consensus Protein Design without Phylogenetic Bias
2010 StandoutNobel
Lysosomes: fusion and function
2007 Standout
A De Novo Protein Binding Pair By Computational Design and Directed Evolution
2011 StandoutNobel
Complete loss of ischaemic preconditioning-induced cardioprotection in mice with partial deficiency of HIF-1
2007 StandoutNobel
Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function
2009 Standout
The Yeast Clathrin Adaptor Protein Complex 1 Is Required for the Efficient Retention of a Subset of Late Golgi Membrane Proteins
2002 StandoutNobel
Designing Repeat Proteins: Well-expressed, Soluble and Stable Proteins from Combinatorial Libraries of Consensus Ankyrin Repeat Proteins
2003
Sorting Signals That Mediate Traffic of Chitin Synthase III between the TGN/Endosomes and to the Plasma Membrane in Yeast
2012 StandoutNobel
Effect of Multiple Prolyl Isomerization Reactions on the Stability and Folding Kinetics of the Notch Ankyrin Domain: Experiment and Theory
2005
PHF8, a gene associated with cleft lip/palate and mental retardation, encodes for an Nε-dimethyl lysine demethylase
2009 StandoutNobel
Notch signaling in the developing cardiovascular system
2007
Structures of CSL, Notch and Mastermind proteins: piecing together an active transcription complex
2006
Anchoring Notch Genetics and Biochemistry
2004
N-Glycosylation Is Essential for Vesicular Targeting of Synaptotagmin 1
2004 StandoutNobel
Structural Basis for Cooperativity in Recruitment of MAML Coactivators to Notch Transcription Complexes
2006
Repeat-protein folding: New insights into origins of cooperativity, stability, and topology
2007
Pre-folding IκBα Alters Control of NF-κB Signaling
2008
Differential Sensitivity of Hypoxia Inducible Factor Hydroxylation Sites to Hypoxia and Hydroxylase Inhibitors
2011 StandoutNobel
Oxygen sensing and hypoxia signalling pathways in animals: the implications of physiology for cancer
2013 StandoutNobel
Notch signalling: a simple pathway becomes complex
2006 Standout
Molecular chaperones in protein folding and proteostasis
2011 StandoutNature
Differential Use of Two AP‐3‐mediated Pathways by Lysosomal Membrane Proteins
2004
Quantitative Mass Spectrometry Reveals Dynamics of Factor-inhibiting Hypoxia-inducible Factor-catalyzed Hydroxylation
2011 StandoutNobel
Intrinsically disordered proteins in cellular signalling and regulation
2014 Standout
Independent Movement, Dimerization and Stability of Tandem Repeats of Chicken Brain α-Spectrin
2004
Hotspot-Centric De Novo Design of Protein Binders
2011 StandoutNobel
Asparaginyl Hydroxylation of the Notch Ankyrin Repeat Domain by Factor Inhibiting Hypoxia-inducible Factor
2007 StandoutNobel
The Energy Landscape of Modular Repeat Proteins: Topology Determines Folding Mechanism in the Ankyrin Family
2005
Beyond Consensus: Statistical Free Energies Reveal Hidden Interactions in the Design of a TPR Motif
2004
Competing sorting signals guide endolyn along a novel route to lysosomes in MDCK cells
2001
Crystal Structure of the CSL-Notch-Mastermind Ternary Complex Bound to DNA
2006
FIH‐Dependent Asparaginyl Hydroxylation of Ankyrin Repeat Domain‐Containing Proteins
2009 StandoutNobel
Ectodomain Shedding and Intramembrane Cleavage of Mammalian Notch Proteins Are Not Regulated through Oligomerization
2004
Computationally Designed Armadillo Repeat Proteins for Modular Peptide Recognition
2016 StandoutNobel
De novo design of buttressed loops for sculpting protein functions
2024 StandoutNobel
Asparagine and Aspartate Hydroxylation of the Cytoskeletal Ankyrin Family Is Catalyzed by Factor-inhibiting Hypoxia-inducible Factor
2010 StandoutNobel
The Contribution of Entropy, Enthalpy, and Hydrophobic Desolvation to Cooperativity in Repeat-Protein Folding
2011
Directionality of Temperature Activation in Mouse TRPA1 Ion Channel Can Be Inverted by Single-Point Mutations in Ankyrin Repeat Six
2014 StandoutNobel
The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism
2009 Standout
Biophysical characterization of the free IκBα ankyrin repeat domain in solution
2004
Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway
2008 StandoutNobel
Exploring the repeat protein universe through computational protein design
2015 StandoutNatureNobel
Folding landscapes of ankyrin repeat proteins: experiments meet theory
2008
Enhancing the Stability and Folding Rate of a Repeat Protein through the Addition of Consensus Repeats
2006
Consensus Design of Repeat Proteins
2004
A General Computational Approach for Repeat Protein Design
2014 StandoutNobel
More complicated than it looks: assembly of Notch pathway transcription complexes
2008
Recognition of dileucine-based sorting signals from HIV-1 Nef and LIMP-II by the AP-1 γ–σ1 and AP-3 δ–σ3 hemicomplexes
2003
Structural Requirements for Assembly of the CSL·Intracellular Notch1·Mastermind-like 1 Transcriptional Activation Complex
2003
Identification and molecular-genetic characterization of a LAMP/CD68-like protein from Caenorhabditis elegans
2000 StandoutNobel
2010 ACCF/AHA/AATS/ACR/ASA/SCA/SCAI/SIR/STS/SVM Guidelines for the Diagnosis and Management of Patients With Thoracic Aortic Disease
2010 Standout
UNC93B1 mediates differential trafficking of endosomal TLRs
2013 StandoutNobel
Extreme stability in de novo-designed repeat arrays is determined by unusually stable short-range interactions
2018 StandoutNobel
Consensus-derived structural determinants of the ankyrin repeat motif
2002
High-resolution crystal structure of the human Notch 1 ankyrin domain
2005
Probing a moving target with a plastic unfolding intermediate of an ankyrin-repeat protein
2007
Posttranslational hydroxylation of ankyrin repeats in IκB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH)
2006 StandoutNobel
Signals for Sorting of Transmembrane Proteins to Endosomes and Lysosomes
2003 Standout
The molecular logic of Notch signaling – a structural and biochemical perspective
2008
MYPT1, the targeting subunit of smooth-muscle myosin phosphatase, is a substrate for the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH)
2009 StandoutNobel
Nuclear entry and export of FIH are mediated by HIF1α and exportin1, respectively
2018 StandoutNobel
The structure of the ankyrin-binding site of β-spectrin reveals how tandem spectrin-repeats generate unique ligand-binding properties
2009 StandoutNobel
Mammalian Late Vacuole Protein Sorting Orthologues Participate in Early Endosomal Fusion and Interact with the Cytoskeleton
2003
The Exomer Coat Complex Transports Fus1p to the Plasma Membrane via a Novel Plasma Membrane Sorting Signal in Yeast
2009 StandoutNobel
The effects of conformational heterogeneity on the binding of the Notch intracellular domain to effector proteins: a case of biologically tuned disorder
2008
Role of Adaptor Complex AP-3 in Targeting Wild-Type and Mutated CD63 to Lysosomes
2002
Phospholipase A2Enzymes: Physical Structure, Biological Function, Disease Implication, Chemical Inhibition, and Therapeutic Intervention
2011 Standout
Ankyrin Repeat: A Unique Motif Mediating Protein−Protein Interactions
2006
Transient Tertiary Structure Formation within the Ribosome Exit Port
2010
A subset of yeast vacuolar protein sorting mutants is blocked in one branch of the exocytic pathway
2002 StandoutNobel
A role for the lysosomal membrane protein LGP85 in the biogenesis and maintenance of endosomal and lysosomal morphology
2002
Works of Mark E. Zweifel being referenced
Relationships between the temperature dependence of solvent denaturation and the denaturant dependence of protein stability curves
2002
Structure and Notch Receptor Binding of the Tandem WWE Domain of Deltex
2005
Structure and stability of the ankyrin domain of the Drosophila Notch receptor
2003
Studies of the Ankyrin Repeats of the Drosophila melanogaster Notch Receptor. 2. Solution Stability and Cooperativity of Unfolding
2001
Utilization of the indirect lysosome targeting pathway by lysosome-associated membrane proteins (LAMPs) is influenced largely by the C-terminal residue of their GYXXФ targeting signals
1999
Studies of the Ankyrin Repeats of the Drosophila melanogaster Notch Receptor. 1. Solution Conformational and Hydrodynamic Properties
2001