Citation Impact
Citing Papers
Mutant SOD1 in cell types other than motor neurons and oligodendrocytes accelerates onset of disease in ALS mice
2008
Non–cell autonomous toxicity in neurodegenerative disorders: ALS and beyond
2009
Several rAAV Vectors Efficiently Cross the Blood–brain Barrier and Transduce Neurons and Astrocytes in the Neonatal Mouse Central Nervous System
2011
Diverse Brain Myeloid Expression Profiles Reveal Distinct Microglial Activation States and Aspects of Alzheimer’s Disease Not Evident in Mouse Models
2018
Mutant Copper-Zinc Superoxide Dismutase (SOD1) Induces Protein Secretion Pathway Alterations and Exosome Release in Astrocytes
2013
Astrocytes: biology and pathology
2009 Standout
Blood–spinal cord barrier breakdown and pericyte reductions in amyotrophic lateral sclerosis
2012
Germline development from human pluripotent stem cells toward disease modeling of infertility
2012 StandoutNobel
Therapeutic AAV9-mediated Suppression of Mutant SOD1 Slows Disease Progression and Extends Survival in Models of Inherited ALS
2013
Converging Mechanisms in ALS and FTD: Disrupted RNA and Protein Homeostasis
2013
Transgenics, toxicity and therapeutics in rodent models of mutant SOD1-mediated familial ALS
2008
ALS: Focus on purinergic signalling
2011
Induced pluripotent stem cells — opportunities for disease modelling and drug discovery
2011
The changing scene of amyotrophic lateral sclerosis
2013
Mechanisms Underlying Inflammation in Neurodegeneration
2010 Standout
CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
2019 StandoutNatureNobel
Molecular mechanisms of epithelial–mesenchymal transition
2014 Standout
Smad transcription factors
2005 Standout
Genome-Wide Identification of Smad/Foxh1 Targets Reveals a Role for Foxh1 in Retinoic Acid Regulation and Forebrain Development
2008
Glial cells as intrinsic components of non-cell-autonomous neurodegenerative disease
2007
Transforming Growth Factor-β Signaling in Immunity and Cancer
2019 Standout
Bone morphogenetic protein receptors and signal transduction
2009 Standout
The Neurovascular Unit Coming of Age: A Journey through Neurovascular Coupling in Health and Disease
2017 Standout
Microglia Induce Motor Neuron Death via the Classical NF-κB Pathway in Amyotrophic Lateral Sclerosis
2014
Microglia and neuroprotection: From in vitro studies to therapeutic applications
2010
The Use of Induced Pluripotent Stem Cells in Drug Development
2011 StandoutNobel
PLGA-based nanoparticles: An overview of biomedical applications
2012 Standout
Microglial cell origin and phenotypes in health and disease
2011 Standout
Amyotrophic lateral sclerosis
2011 Standout
Technical Challenges in Using Human Induced Pluripotent Stem Cells to Model Disease
2009
Transforming Growth Factor-β Signaling during Epithelial-Mesenchymal Transformation: Implications for Embryogenesis and Tumor Metastasis
2005
An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex
2014 Standout
Mice exclusively expressing the short isoform of Smad2 develop normally and are viable and fertile
2005
Distribution of dipeptide repeat proteins in cellular models and C9orf72 mutation cases suggests link to transcriptional silencing
2015
Single-Molecule Dynamics of Enhanceosome Assembly in Embryonic Stem Cells
2014 StandoutNobel
Intravascular AAV9 preferentially targets neonatal neurons and adult astrocytes
2008
Dose-dependent Smad1, Smad5 and Smad8 signaling in the early mouse embryo
2006
Gene function in mouse embryogenesis: get set for gastrulation
2007
Decoding ALS: from genes to mechanism
2016 StandoutNature
The single-cell transcriptional landscape of mammalian organogenesis
2019 StandoutNature
Reactive oxygen species trigger motoneuron death in non-cell-autonomous models of ALS through activation of c-Abl signaling
2015
TGFβ and BMP signaling in cardiac cushion formation: Lessons from mice and chicken
2012
Systemic AAV9 gene transfer in adult GM1 gangliosidosis mice reduces lysosomal storage in CNS and extends lifespan
2015
Microfluidic organs-on-chips
2014 Standout
Antioxidant gene therapy against neuronal cell death
2013
Defective pulmonary vascular remodeling in Smad8 mutant mice
2009
Bio-printing of collagen and VEGF-releasing fibrin gel scaffolds for neural stem cell culture
2010
Hypoxia inducible factor-1-dependent up-regulation of BMP4 mediates hypoxia-induced increase of TRPC expression in PASMCs
2015 StandoutNobel
Immune-mediated Mechanisms in the Pathoprogression of Amyotrophic Lateral Sclerosis
2013
Direct reprogramming 101
2010
Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity
2012 Standout
Astrocytes conspire with neurons during progression of neurological disease
2012
Muscle Mitochondrial Uncoupling Dismantles Neuromuscular Junction and Triggers Distal Degeneration of Motor Neurons
2009
TGFβ in Cancer
2008 Standout
Oxidative Stress in Cancer
2020 Standout
Adeno-associated virus vector as a platform for gene therapy delivery
2019 Standout
Orderly hematopoietic development of induced pluripotent stem cells via Flk‐1+ hemoangiogenic progenitors
2009 StandoutNobel
The Seeds of Neurodegeneration: Prion-like Spreading in ALS
2011
MicroRNA-regulated, Systemically Delivered rAAV9: A Step Closer to CNS-restricted Transgene Expression
2010 Nobel
Elusive roles for reactive astrocytes in neurodegenerative diseases
2015
Blood-Brain Barrier Breakdown in the Aging Human Hippocampus
2015 Standout
A 3D bioprinting system to produce human-scale tissue constructs with structural integrity
2016 Standout
Reactive Astrocytes: Production, Function, and Therapeutic Potential
2017 Standout
The basics of epithelial-mesenchymal transition
2009 Standout
Directed Evolution of Adeno-associated Virus for Enhanced Gene Delivery and Gene Targeting in Human Pluripotent Stem Cells
2011
Vascular endothelial growth factor: a neurovascular target in neurological diseases
2016
TGF-β-induced epithelial to mesenchymal transition
2009 Standout
Necroptosis Drives Motor Neuron Death in Models of Both Sporadic and Familial ALS
2014
The amyloid state and its association with protein misfolding diseases
2014 Standout
Glia cells in amyotrophic lateral sclerosis: New clues to understanding an old disease?
2007
Oxidative Stress: Harms and Benefits for Human Health
2017 Standout
Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders
2011 Standout
Activin receptor‐like kinase5 inhibition suppresses mouse melanoma by ubiquitin degradation of Smad4, thereby derepressing eomesodermin in cytotoxic T lymphocytes
2014
Activin receptor‐like kinase5 inhibition suppresses mouse melanoma by ubiquitin degradation of Smad4, thereby derepressing eomesodermin in cytotoxic T lymphocytes
2013
Recombinant Adeno-Associated Virus-Mediated Global Anterograde Delivery of Glial Cell Line-Derived Neurotrophic Factor to the Spinal Cord: Comparison of Rubrospinal and Corticospinal Tracts in the Rat
2007
Adeno-Associated Virus-Based Gene Therapy for CNS Diseases
2016
Astrocyte–neuron co-culture on microchips based on the model of SOD mutation to mimic ALS
2013
Superoxide Dismutases and Superoxide Reductases
2014
Adeno‐associated virus–delivered artificial microRNA extends survival and delays paralysis in an amyotrophic lateral sclerosis mouse model
2016
Copper Active Sites in Biology
2014 Standout
Directed induction of anterior and posterior primitive streak by Wnt from embryonic stem cells cultured in a chemically defined serum‐free medium
2008
Rapid and Deep Profiling of Human Induced Pluripotent Stem Cell Proteome by One-shot NanoLC–MS/MS Analysis with Meter-scale Monolithic Silica Columns
2012 StandoutNobel
Modeling hepatitis C virus infection using human induced pluripotent stem cells
2012 StandoutNobel
Evaluation of Readministration of a Recombinant Adeno-Associated Virus Vector Expressing Acid Alpha-Glucosidase in Pompe Disease: Preclinical to Clinical Planning
2015
Microglia Function in the Central Nervous System During Health and Neurodegeneration
2017 Standout
SOD1 Function and Its Implications for Amyotrophic Lateral Sclerosis Pathology
2014
In vivo genome editing improves motor function and extends survival in a mouse model of ALS
2017
Myocardin Enhances Smad3-Mediated Transforming Growth Factor-β 1 Signaling in a CArG Box-Independent Manner
2005
Spermidine in health and disease
2018 StandoutScience
How neuroinflammation contributes to neurodegeneration
2016 StandoutScience
Inositol Polyphosphate Multikinase Inhibits Angiogenesis via Inositol Pentakisphosphate-Induced HIF-1α Degradation
2017 StandoutNobel
Deletion of Smad2 in Mouse Liver Reveals Novel Functions in Hepatocyte Growth and Differentiation
2005
Liquid-Liquid Phase Separation in Biology
2014 Standout
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Superoxide Ion: Generation and Chemical Implications
2016 Standout
Microglial M1/M2 polarization and metabolic states
2015 Standout
Blood–spinal cord barrier disruption contributes to early motor-neuron degeneration in ALS-model mice
2014
Neurons generated by direct conversion of fibroblasts reproduce synaptic phenotype caused by autism-associated neuroligin-3 mutation
2013 StandoutNobel
Targeted gene knock-in by homology-directed genome editing using Cas9 ribonucleoprotein and AAV donor delivery
2017 StandoutNobel
Generation of GFAP::GFP astrocyte reporter lines from human adult fibroblast‐derived iPS cells using zinc‐finger nuclease technology
2015
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
Additive manufacturing (3D printing): A review of materials, methods, applications and challenges
2018 Standout
Oxidative Stress: A Key Modulator in Neurodegenerative Diseases
2019 Standout
The epithelial–mesenchymal transition: new insights in signaling, development, and disease
2006 Standout
Works of Mark E. Hester being referenced
AAV4-mediated Expression of IGF-1 and VEGF Within Cellular Components of the Ventricular System Improves Survival Outcome in Familial ALS Mice
2010
Rapid and Efficient Generation of Functional Motor Neurons From Human Pluripotent Stem Cells Using Gene Delivered Transcription Factor Codes
2011
Generation of novel conditional and hypomorphic alleles of the Smad2 gene
2004
Smad2 and Smad3 coordinately regulate craniofacial and endodermal development
2004
AAV as a Gene Transfer Vector for the Treatment of Neurological Disorders: Novel Treatment Thoughts for ALS
2009
Two Factor Reprogramming of Human Neural Stem Cells into Pluripotency
2009
Astrocytes from familial and sporadic ALS patients are toxic to motor neurons
2011
Aging brain microenvironment decreases hippocampal neurogenesis through Wnt‐mediated survivin signaling
2012
Delivery of AAV-IGF-1 to the CNS Extends Survival in ALS Mice Through Modification of Aberrant Glial Cell Activity
2008
Gene transfer demonstrates that muscle is not a primary target for non-cell-autonomous toxicity in familial amyotrophic lateral sclerosis
2006
Smad1 and Smad8 Function Similarly in Mammalian Central Nervous System Development
2005