Citation Impact
Citing Papers
De novo protein synthesis is required for the activation-induced cytidine deaminase function in class-switch recombination
2003 StandoutNobel
Control of Regulatory T Cell Development by the Transcription Factor Foxp3
2003 StandoutScienceNobel
Effective expansion of alloantigen-specific Foxp3 + CD25 + CD4 + regulatory T cells by dendritic cells during the mixed leukocyte reaction
2006 StandoutNobel
A2A Adenosine Receptor May Allow Expansion of T Cells Lacking Effector Functions in Extracellular Adenosine-Rich Microenvironments
2009
IL-10: The Master Regulator of Immunity to Infection
2008 Standout
ERβ: Identification and characterization of a novel human estrogen receptor
1996 Standout
Structures of MLSBK Antibiotics Bound to Mutated Large Ribosomal Subunits Provide a Structural Explanation for Resistance
2005 StandoutNobel
Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration
1995 StandoutNobel
15-Deoxy-Δ12,14-Prostaglandin J2 is a ligand for the adipocyte determination factor PPARγ
1995 Standout
The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation
1998 StandoutNature
IL-10 Inhibits the Primary Allogeneic T Cell Response to Human Peripheral Blood Dendritic Cells
1995
Nonsteroidal progesterone receptor antagonists based on 6-thiophenehydroquinolines
2000
Crystal Structures of 8-Cl and 9-Cl TIBO Complexed with Wild-type HIV-1 RT and 8-Cl TIBO Complexed with the Tyr181Cys HIV-1 RT Drug-resistant Mutant
1996
Crystal Structure of a pol α Family Replication DNA Polymerase from Bacteriophage RB69
1997 StandoutNobel
Transcription Activation by the Human Estrogen Receptor Subtypeβ (ERβ) Studied with ERβ and ERα Receptor Chimeras1
1998
Treatment of Bone-Derived ROS 17/2.8 Cells with Dexamethasone and Pertussis Toxin Enables Detection of Partial Agonist Activity for Parathyroid Hormone Antagonists
1990
Structure of the Replicating Complex of a Pol α Family DNA Polymerase
2001 StandoutNobel
Inhibition of α-helix-mediated protein–protein interactions using designed molecules
2013
Functional Synergy between the Transcription Factor Sp1 and the Estrogen Receptor
1997
The IKK NF-κB system: a treasure trove for drug development
2004
Pregnancy Maintenance and Parturition: The Role of Prostaglandin in Manipulating the Immune and Inflammatory Response
1994
The Human Estrogen Receptor-α Is a Ubiquitinated Protein Whose Stability Is Affected Differentially by Agonists, Antagonists, and Selective Estrogen Receptor Modulators
2001
Asymmetric spiroacetalization catalysed by confined Brønsted acids
2012 StandoutNatureNobel
p300 and estrogen receptor cooperatively activate transcription via differential enhancement of initiation and reinitiation
1998
Tamoxifen resistant breast cancer: coregulators determine the direction of transcription by antagonist-occupied steroid receptors
1999
Enzymatic assembly of carbon–carbon bonds via iron-catalysed sp3 C–H functionalization
2018 StandoutNatureNobel
Regulating immunity to malaria
2005
Differential Response of Estrogen Receptor α and Estrogen Receptor β to Partial Estrogen Agonists/Antagonists
1998
Different Regions in Activation Function-1 of the Human Estrogen Receptor Required for Antiestrogen- and Estradiol-dependent Transcription Activation
1996
Analysis of pharmacologic inhibitors of Jun N-terminal kinases
2001
Nuclear factor-κB in cancer development and progression
2006 StandoutNature
A Computationally Designed Inhibitor of an Epstein-Barr Viral Bcl-2 Protein Induces Apoptosis in Infected Cells
2014 StandoutNobel
Constraining Cyclic Peptides To Mimic Protein Structure Motifs
2014
Interleukin‐10 prevents the generation of dendritic cells from human peripheral blood mononuclear cells cultured with interleukin‐4 and granulocyte/ macrophage‐colony‐stimulating factor
1997
Declining Morbidity and Mortality among Patients with Advanced Human Immunodeficiency Virus Infection
1998 Standout
IL-10 from CD4+CD25−Foxp3−CD127− Adaptive Regulatory T Cells Modulates Parasite Clearance and Pathology during Malaria Infection
2008
Click Chemistry: Diverse Chemical Function from a Few Good Reactions
2001 StandoutNobel
Structure of Taq polymerase with DNA at the polymerase active site
1996 StandoutNatureNobel
The novel estrogen receptor‐β subtype: potential role in the cell‐ and promoter‐specific actions of estrogens and anti‐estrogens
1997
Changes in Plasma HIV-1 RNA and CD4+ Lymphocyte Counts and the Risk of Progression to AIDS
1996
Growth factor activation of the estrogen receptor in vascular cells occurs via a mitogen-activated protein kinase-independent pathway.
1998
Osteoclast differentiation and activation
2003 StandoutNature
Sensitization of diabetic and obese mice to insulin by retinoid X receptor agonists
1997 Nature
HIV as the cause of AIDS
1996 StandoutNobel
The hormone resistin links obesity to diabetes
2001 StandoutNature
Structure of HIV-1 RT/TIBO R 86183 complex reveals similarity in the binding of diverse nonnucleoside inhibitors
1995
The Estrogen Receptor β Subtype: A Novel Mediator of Estrogen Action in Neuroendocrine Systems
1998
Ligand-independent activation of steroid hormone receptors
1998
Role of interleukin 10 in specific immunotherapy.
1998 Standout
Switching androgen receptor antagonists to agonists by modifying C-ring substituents on piperidino[3,2-g]quinolinone
1999
Discovery of nonsteroidal glucocorticoid receptor ligands based on 6-indole-1,2,3,4-tetrahydroquinolines
2008
HIV Drug Resistance
1992
Protozoan encounters with Toll-like receptor signalling pathways: implications for host parasitism
2006
Determinants for the repression of estrogen receptor transcriptional activity by ligand-occupied progestin receptors
1997
Different positioning of the ligand-binding domain helix 12and the F domain of the estrogen receptor accounts for functional differences between agonists and antagonists
1998
Inhibition of HIV-1 integration protein by aurintricarboxylic acid monomers, monomer analogs, and polymer fractions
1992
High resolution structures of HIV-1 RT from four RT–inhibitor complexes
1995
Structure of HIV-1 reverse transcriptase in a complex with the non-nucleoside inhibitor α-APA R 95845 at 2.8 å resolution
1995
Unique response pathways are established by allosteric interactions among nuclear hormone receptors
1995
Single-cell analysis of cyclic AMP response to parathyroid hormone in osteoblastic cells
1994 StandoutNobel
RTP4 inhibits IFN-I response and enhances experimental cerebral malaria and neuropathology
2020 StandoutNobel
2',5'-Bis-O-(tert-butyldimethylsilyl)-3'-spiro-5''-(4''-amino-1'',2''- oxathiole-2'',2'-dioxide)pyrimidine (TSAO) nucleoside analogues: highlyselective inhibitors of human immunodeficiency virus type 1 that are targeted at the viral reverse transcriptase.
1992
Retinoid-dependent pathways suppress myocardial cell hypertrophy.
1995
Methodologies for Generating Solution-Phase Combinatorial Libraries
2000
Tissue Distribution and Quantitative Analysis of Estrogen Receptor-α (ERα) and Estrogen Receptor-β (ERβ) Messenger Ribonucleic Acid in the Wild-Type and ERα-Knockout Mouse
1997
Ligand-dependent interactions of coactivators steroid receptor coactivator-1 and peroxisome proliferator-activated receptor binding protein with nuclear hormone receptors can be imaged in live cells and are required for transcription
2000 StandoutNobel
Chimeric human immunodeficiency virus type 1/type 2 reverse transcriptases display reversed sensitivity to nonnucleoside analog inhibitors.
1991
Coactivator and Corepressor Regulation of the Agonist/Antagonist Activity of the Mixed Antiestrogen, 4-Hydroxytamoxifen
1997
Orphan Nuclear Receptors: From Gene to Function*
1999
SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase
2001 Standout
Structure of the binding site for nonnucleoside inhibitors of the reverse transcriptase of human immunodeficiency virus type 1.
1994 StandoutNobel
A General Method for Constraining Short Peptides to an α-Helical Conformation
1997
Abnormal Vascular Function and Hypertension in Mice Deficient in Estrogen Receptor β
2002 StandoutScienceNobel
ExBox: A Polycyclic Aromatic Hydrocarbon Scavenger
2012 StandoutNobel
Estrogen receptor (ER) modulators each induce distinct conformational changes in ER α and ER β
1999
Structure of HIV-1 reverse transcriptase/DNA complex at 7 Å resolution showing active site locations
1992 Nature
The Pathogenesis of Schistosomiasis Is Controlled by Cooperating IL-10-Producing Innate Effector and Regulatory T Cells
2004
Generation and reproductive phenotypes of mice lacking estrogen receptor β
1998 StandoutNobel
Bacterial Biofilms: A Common Cause of Persistent Infections
1999 StandoutScience
Analysis of nonnucleoside drug-resistant variants of human immunodeficiency virus type 1 reverse transcriptase
1993
The Estrogen Receptor Enhances AP-1 Activity by Two Distinct Mechanisms with Different Requirements for Receptor Transactivation Functions
1999
Direct Visualization of the Human Estrogen Receptor α Reveals a Role for Ligand in the Nuclear Distribution of the Receptor
1999
Selection of an RNA molecule that mimics a major autoantigenic epitope of human insulin receptor.
1995 StandoutNobel
An efficient synthetic route to chiral 4-alkyl-1,2,3,4-tetrahydroquinolines: enantioselective synthesis of (R)-4-ethyl-1,2,3,4-tetrahydroquinoline
2000
Advances in the Chemistry of Tetrahydroquinolines
2011 Standout
Mechanisms of Estrogen Action
2001 Standout
Essential role of β-adrenergic receptor kinase 1 in cardiac development and function
1996 StandoutNobel
Mechanism of Inhibition of HIV-1 Reverse Transcriptase by Nonnucleoside Inhibitors
1995 Science
Synthesis and Biological Activity of a Novel Series of Nonsteroidal, Peripherally Selective Androgen Receptor Antagonists Derived from 1,2-Dihydropyridono[5,6-g]quinolines
1998
Analysis of estrogen receptor transcriptional enhancement by a nuclear hormone receptor coactivator.
1996
The Molecular Pharmacology of SERMs
1999
Chemotherapy induces enrichment of CD47 + /CD73 + /PDL1 + immune evasive triple-negative breast cancer cells
2018 StandoutNobel
De novo design of covalently constrained mesosize protein scaffolds with unique tertiary structures
2017 StandoutNobel
Estrogen Receptor-β mRNA Expression in Rat Ovary: Down-Regulation by Gonadotropins
1997
Crystallization of ribozymes and small RNA motifs by a sparse matrix approach.
1993 StandoutNobel
Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
2002 StandoutNobel
A Chimeric Form of Osteoprotegerin Inhibits Hypercalcemia and Bone Resorption Induced by IL-1β, TNF-α, PTH, PTHrP, and 1,25(OH)2D3
1999
Interleukin-10 and the Interleukin-10 Receptor
2001 Standout
Sensitivity of wild-type human immunodeficiency virus type 1 reverse transcriptase to dideoxynucleotides depends on template length; the sensitivity of drug-resistant mutants does not.
1994
Click Chemistry: Diverse Chemical Function from a Few Good Reactions
2001 StandoutNobel
Human immunodeficiency virus type 1 mutants resistant to nonnucleoside inhibitors of reverse transcriptase arise in tissue culture.
1991
β-Defensins: Linking Innate and Adaptive Immunity Through Dendritic and T Cell CCR6
1999 StandoutScience
A mutation in reverse transcriptase of bis(heteroaryl)piperazine-resistant human immunodeficiency virus type 1 that confers increased sensitivity to other nonnucleoside inhibitors.
1993
Estrogen Receptor β Activates the Human Retinoic Acid Receptorα -1 Promoter in Response to Tamoxifen and Other Estrogen Receptor Antagonists, but Not in Response to Estrogen
1999
Rubromycins: Structurally Intriguing, Biologically Valuable, Synthetically Challenging Antitumour Antibiotics
2007
Structure of DNA Polymerase I Klenow Fragment Bound to Duplex DNA
1993 StandoutScienceNobel
A Defect in Interleukin-10 Leads to Enhanced Malarial Disease inPlasmodium chabaudi chabaudiInfection in Mice
1999
Functional analysis of HIV-1 reverse transcriptase amino acids involved in resistance to multiple nonnucleoside inhibitors.
1992
Synthesis, Structure−Activity Relationships, and RARγ−Ligand Interactions of Nitrogen Heteroarotinoids
1999
Pathology ofPlasmodium chabaudi chabaudiInfection and Mortality in Interleukin-10-Deficient Mice Are Ameliorated by Anti-Tumor Necrosis Factor Alpha and Exacerbated by Anti-Transforming Growth Factor β Antibodies
2003
Subunit specificity of mutations that confer resistance to nonnucleoside inhibitors in human immunodeficiency virus type 1 reverse transcriptase
1994
Cancer risk assessment, indicators, and guidelines for polycyclic aromatic hydrocarbons in the ambient air.
2002
Structure of HIV-1 reverse transcriptase bound to an inhibitor active against mutant reverse transcriptases resistant to other nonnucleoside inhibitors
2004 StandoutNobel
Activation of naïve B lymphocytes via CD81, a pathogenetic mechanism for hepatitis C virus-associated B lymphocyte disorders
2005 StandoutNobel
3'-Azido-3'-deoxythymidine resistance suppressed by a mutation conferring human immunodeficiency virus type 1 resistance to nonnucleoside reverse transcriptase inhibitors
1992
Identification of Estrogen Receptor β2, A Functional Variant of Estrogen Receptor β Expressed in Normal Rat Tissues
1998
Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 A resolution shows bent DNA.
1993
Multiple Signal Input and Output Domains of the 160-Kilodalton Nuclear Receptor Coactivator Proteins
1999
Complexes of HIV-1 Reverse Transcriptase with Inhibitors of the HEPT Series Reveal Conformational Changes Relevant to the Design of Potent Non-Nucleoside Inhibitors
1996
Inhibitors of human immunodeficiency virus integrase.
1993 StandoutNobel
RNA pseudoknots that inhibit human immunodeficiency virus type 1 reverse transcriptase.
1992
Discovery of a Potent, Orally Active, Nonsteroidal Androgen Receptor Agonist: 4-Ethyl-1,2,3,4-tetrahydro-6- (trifluoromethyl)-8-pyridono[5,6-g]- quinoline (LG121071)
1999
L-743, 726 (DMP-266): a novel, highly potent nonnucleoside inhibitor of the human immunodeficiency virus type 1 reverse transcriptase
1995
The telomerase RNA pseudoknot is critical for the stable assembly of a catalytically active ribonucleoprotein
1999 StandoutNobel
Phosphorylation of Human Estrogen Receptor α by Protein Kinase A Regulates Dimerization
1999
HIV-1-infected monocyte-derived dendritic cells do not undergo maturation but can elicit IL-10 production and T cell regulation
2004 StandoutNobel
Human CD4+CD25+ Regulatory, Contact-dependent T Cells Induce Interleukin 10–producing, Contact-independent Type 1-like Regulatory T Cells
2002
Comprehensive mutant enzyme and viral variant assessment of human immunodeficiency virus type 1 reverse transcriptase resistance to nonnucleoside inhibitors
1993
Nuclear Receptors Have Distinct Affinities for Coactivators: Characterization by Fluorescence Resonance Energy Transfer
1998
Therapeutic Approaches to Bone Diseases
2000 Science
The Connectivity Map: Using Gene-Expression Signatures to Connect Small Molecules, Genes, and Disease
2006 StandoutScience
Steroid hormone receptors and their regulation by phosphorylation
1996
Hyper Immunoglobulin E Response in Mice with Monoclonal Populations of B and T Lymphocytes✪
2001
Estrogen inhibits the vascular injury response in estrogen receptor β-deficient female mice
1999 StandoutNobel
Unique features in the structure of the complex between HIV-1 reverse transcriptase and the bis(heteroaryl)piperazine (BHAP) U-90152 explain resistance mutations for this nonnucleoside inhibitor
1997
Works of Mark E. Goldman being referenced
Inhibition of human immunodeficiency virus-1 reverse transcriptase activity by rubromycins: competitive interaction at the template.primer site.
1990
Cyclic parathyroid hormone-related protein antagonists: lysine 13 to aspartic acid 17 [i to (i + 4)] side chain to side chain lactamization
1991
Synthesis and Structure-Activity Relationships of Novel Retinoid X Receptor-Selective Retinoids
1994
Synthesis of a Series of 4-(Arylethynyl)-6-chloro-4-cyclopropyl-3,4-dihydroquinazolin-2(1H)-ones as Novel Non-nucleoside HIV-1 Reverse Transcriptase Inhibitors
1994
2-Pyridinone derivatives: a new class of nonnucleoside, HIV-1-specific reverse transcriptase inhibitors
1991
The human progesterone receptor A-form functions as a transcriptional modulator of mineralocorticoid receptor transcriptional acitivity
1994
THE 7–34-FRAGMENT OF HUMAN HYPERCALCEMIA FACTOR IS A PARTIAL AGONIST/ANTAGONIST FOR PARATHYROID HORMONESTIMULATED CAMP PRODUCTION
1988
Structure–Activity Relationship Studies of Ethyl 2-[(3-Methyl-2,5-dioxo(3-pyrrolinyl))amino]-4-(trifluoromethyl)pyrimidine-5-carboxylate: An Inhibitor of AP-1 and NF-κB Mediated Gene Expression
2002
Evaluation of Novel Parathyroid Hormone Analogs Using a Bovine Renal Membrane Receptor Binding Assay
1988
Modifications of position 12 in a parathyroid hormone and parathyroid hormone-related protein: toward the design of highly potent antagonists
1990
Nonsteroidal progesterone receptor antagonists based on a conformationally-restricted subseries of 6-aryl-1,2-dihydro-2,2,4-trimethylquinolines
1998
Synthesis of high specific activity tritium-labeled [3H]-9-cis-retinoic acid and its application for identifying retinoids with unusual binding properties
1994
Interleukin‐10 modulates susceptibility in experimental cerebral malaria
1997
Nonsteroidal androgen receptor agonists based on 4-(trifluoromethyl)-2H-pyrano[3,2-g]quinolin-2-one
1999
Synthesis and anti-HIV activities of low molecular weight aurintricarboxylic acid fragments and related compounds
1991
A Tumor‐Secreted Protein Associated with Human Hypercalcemia of Malignancy
1988
A NEW HIGHLY POTENT PARATHYROID HORMONE ANTAGONIST: [D-TRPl2,TYR34]bPTH-(7–34)NH2
1988
Discovery of novel intracellular receptor modulating drugs
1996
Preparation and anti-HIV activities of aurintricarboxylic acid fractions and analogs: direct correlation of antiviral potency with molecular weight
1991
Pyridinone derivatives: specific human immunodeficiency virus type 1 reverse transcriptase inhibitors with antiviral activity.
1991
L-696,229 specifically inhibits human immunodeficiency virus type 1 reverse transcriptase and possesses antiviral activity in vitro
1992
Synthesis and Biological Activity of Novel Nonsteroidal Progesterone Receptor Antagonists Based on Cyclocymopol Monomethyl Ether
1996
2-Chloro-4-(trifluoromethyl)pyrimidine-5-N-(3‘,5‘-bis(trifluoromethyl)phenyl)- carboxamide: A Potent Inhibitor of NF-κB- and AP-1-Mediated Gene Expression Identified Using Solution-Phase Combinatorial Chemistry
1998
RU486 exerts antiestrogenic activities through a novel progesterone receptor A form-mediated mechanism.
1994
Book Review
1997
Viral resistance to human immunodeficiency virus type 1-specific pyridinone reverse transcriptase inhibitors
1991
Human progesterone receptor A form is a cell- and promoter-specific repressor of human progesterone receptor B function.
1993
Analysis of estrogen receptor function in vitro reveals three distinct classes of antiestrogens.
1995
Development of a Nonradioactive, Time-Resolved Fluorescence Assay for the Measurement of Jun N-Terminal Kinase Activity
1997
A nonnucleoside reverse transcriptase inhibitor active on human immunodeficiency virus type 1 isolates resistant to related inhibitors
1993
Adenosine enhances IL-10 secretion by human monocytes.
1996
Tumorigenicity of fluoranthene in a newborn mouse lung adenoma bioassay
1984
The A and B isoforms of the human progesterone receptor operate through distinct signaling pathways within target cells.
1994
B7/CD28-dependent IL-5 production by human resting T cells is inhibited by IL-10.
1994
Discovery and Preliminary SAR Studies of a Novel, Nonsteroidal Progesterone Receptor Antagonist Pharmacophore
1998