Citation Impact
Citing Papers
Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels
2010 StandoutScienceNobel
Direct conversion of fibroblasts to functional neurons by defined factors
2010 StandoutNatureNobel
Stimulation of p21ras upon T-cell activation
1990 Nature
Molecular investigations on the high-affinity nerve growth factor receptor
1991
Role of ERas in promoting tumour-like properties in mouse embryonic stem cells
2003 StandoutNatureNobel
Model for signal sequence recognition from amino-acid sequence of 54K subunit of signal recognition particle
1989 StandoutNatureNobel
The neurotrophic factors brain-derived neurotrophic factor and neurotrophin-3 are ligands for the trkB tyrosine kinase receptor
1991
The cytoplasmic protein GAP is implicated as the target for regulation by the ras gene product
1988 Nature
ERKs: A family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF
1991 Standout
Instability and decay of the primary structure of DNA
1993 StandoutNatureNobel
Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
2006 StandoutNobel
A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans
1996 StandoutNatureNobel
Isolation of Angiopoietin-1, a Ligand for the TIE2 Receptor, by Secretion-Trap Expression Cloning
1996 Standout
Structure of the recA protein–ADP complex
1992 StandoutNatureNobel
Structure of the guanine-nucleotide-binding domain of the Ha-ras oncogene product p21 in the triphosphate conformation
1989 Nature
The origin of pattern and polarity in the Drosophila embryo
1992 StandoutNobel
Spontaneous deamination of cytosine and 5-methylcytosine residues in DNA and replacement of 5-methylcytosine residues with cytosine residues
1990
Linkage of a prion protein missense variant to Gerstmann–Sträussler syndrome
1989 StandoutNatureNobel
Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis
1994 StandoutScienceNobel
Phosphatidylinositol-3-OH kinase direct target of Ras
1994 StandoutNature
All ras proteins are polyisoprenylated but only some are palmitoylated
1989 Standout
Stem Cells, the Molecular Circuitry of Pluripotency and Nuclear Reprogramming
2008
The immune response of Drosophila
2003 StandoutNatureNobel
Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition
2001 StandoutNatureNobel
The small GTP-binding protein rac regulates growth factor-induced membrane ruffling
1992 Standout
NF‐L and peripherin immunoreactivities define distinct classes of rat sensory ganglion cells
1991
The ras gene family and human carcinogenesis
1988
Trkl3 mediates BDNF/NT-3-dependent survival and proliferation in fibroblasts lacking the low affinity NGF receptor
1991
Programmed population control by cell–cell communication and regulated killing
2004 StandoutNatureNobel
Alternative forms of rat TrkC with different functional capabilities
1993
The changing sensitivity in the life of the nociceptor
1999
Cellular ras activity and phospholipid metabolism
1988
Mechanisms of intracellular protein transport
1994 StandoutNatureNobel
Universal control mechanism regulating onset of M-phase
1990 StandoutNatureNobel
Activation of Ki-ras2 gene in human colon and lung carcinomas by two different point mutations
1983 Nature
Behavior of myc and ras Oncogenes in Transformation of Rat Embryo Fibroblasts
1986
Three-Dimensional Structure of an Oncogene Protein: Catalytic Domain of Human c-H- ras P21
1988 Science
Activating mutations of the c-Ha-ras protooncogene in chemically induced hepatomas of the male B6C3 F1 mouse.
1986
The long and the short of long–term memory—a molecular framework
1986 StandoutNatureNobel
Cellular Oncogenes and Multistep Carcinogenesis
1983 Science
Refined crystal structure of the triphosphate conformation of H-ras p21 at 1.35 A resolution: implications for the mechanism of GTP hydrolysis.
1990
Malignant transformation of early passage rodent cells by a single mutated human oncogene
1984 Nature
Small GTP-Binding Proteins
2001 Standout
Predicted nucleotide-binding properties of p21 protein and its cancer-associated variant
1983 Nature
Checkpoints: Controls That Ensure the Order of Cell Cycle Events
1989 StandoutScienceNobel
Genes in S. cerevisiae encoding proteins with domains homologous to the mammalian ras proteins
1984
Nucleotide sequences of the separate origins of synthesis of bacteriophage G4 viral and complementary DNA strands.
1978
The p21 ras C-terminus is required for transformation and membrane association
1984 Nature
Rous sarcoma virus variants that carry the cellular src gene instead of the viral src gene cannot transform chicken embryo fibroblasts.
1984
Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture
1983 Nature
Direct identification of palmitic acid as the lipid attached to p21ras.
1986
Ligands for EPH-Related Receptor Tyrosine Kinases that Require Membrane Attachment or Clustering for Activity
1994 Science
Structure and organization of the human Ki-ras proto-oncogene and a related processed pseudogene
1983 Nature
Requirement for ras proto-oncogene function during serum-stimulated growth of NIH 3T3 cells
1985 Nature
The Action of Oncogenes in the Cytoplasm and Nucleus
1985 Science
Receptor-tyrosine-kinase- and Gβγ-mediated MAP kinase activation by a common signalling pathway
1995 StandoutNatureNobel
Angiopoietin-2, a Natural Antagonist for Tie2 That Disrupts in vivo Angiogenesis
1997 StandoutScience
RAM, a gene of yeast required for a functional modification of RAS proteins and for production of mating pheromone a-factor
1986
THE MOLECULAR GENETICS OF CELLULAR ONCOGENES
1984
Activation of the transforming potential of p60c-src by a single amino acid change.
1986
Amplification of N- myc in Untreated Human Neuroblastomas Correlates with Advanced Disease Stage
1984 StandoutScienceNobel
Charon Phages: Safer Derivatives of Bacteriophage Lambda for DNA Cloning
1977 StandoutScienceNobel
Biological properties of human c-Ha-ras1 genes mutated at codon 12
1984 Nature
v-ras genes from harvey and BALB murine sarcoma viruses can act as initiators of two-stage mouse skin carcinogenesis
1986
Biochemical characterization of polypeptides encoded by mutated human Ha-ras1 genes.
1986
A new cell division operon inEscherichia coli
1986
Dynamic fatty acylation of p21N-ras.
1987
Experimental metastasis in nude mice of NIH 3T3 cells containing various ras genes.
1986
Inhibition of NIH 3T3 Cell Proliferation by a Mutant ras Protein with Preferential Affinity for GDP
1988
Myristoylated alpha subunits of guanine nucleotide-binding regulatory proteins.
1987 StandoutNobel
Infection of immune mast cells by Harvey sarcoma virus: immortalization without loss of requirement for interleukin-3.
1985
DNA sequencing with chain-terminating inhibitors
1977 StandoutNobel
Inhibition by brefeldin A of a Golgi membrane enzyme that catalyses exchange of guanine nucleotide bound to ARF
1992 StandoutNatureNobel
A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder carcinoma oncogene
1982 Nature
A human gastric carcinoma contains a single mutated and an amplified normal allele of the Ki-rasoncogene
1986
Ha-ras proteins exhibit GTPase activity: point mutations that activate Ha-ras gene products result in decreased GTPase activity.
1985
The N-rasoncogene assigned to the short arm of human chromosome 1
1983
Effect of a dominant inhibitory Ha-ras mutation on mitogenic signal transduction in NIH 3T3 cells.
1990
Structural Determinants of Ion Flow Through Recombinant Glutamate Receptor Channels
1991 StandoutScienceNobel
A cellular oncogene (c-Ki-ras) is amplified, overexpressed, and located within karyotypic abnormalities in mouse adrenocortical tumour cells
1983 StandoutNatureNobel
Amino-acid substitutions at codon 13 of the N-ras oncogene in human acute myeloid leukaemia
1985 Nature
Induction of Membrane Ruffling and Fluid-Phase Pinocytosis in Quiescent Fibroblasts by ras Proteins
1986 Science
A novel ras-related gene family
1985 StandoutNobel
The Genome of Simian Virus 40
1978 Science
Oncogene amplification during tumorigenesis of established rat fibroblasts reversibly transformed by activated human ras oncogenes.
1986
Down-modulation of an oncogene protein product and reversion of the transformed phenotype by monoclonal antibodies
1985
Expression of v-src and chicken c-src in rat cells demonstrates qualitative differences between pp60v-src and pp60c-src
1984 StandoutNobel
A product of yeast RAS2 gene is a guanine nucleotide binding protein.
1984
Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour
1983 StandoutNatureNobel
A molecular approach to leukemogenesis: mouse lymphomas contain an activated c-ras oncogene.
1984
Mutagenesis of the Ha-ras oncogene in mouse skin tumors induced by polycyclic aromatic hydrocarbons.
1986
Intrinsic GTPase activity distinguishes normal and oncogenic ras p21 molecules.
1984
A novel transforming gene in a human malignant melanoma cell line
1984 Nature
Gene Amplification of c- myc and N- myc in Small Cell Carcinoma of the Lung
1986 Science
c-Ha-ras-1 proto-oncogene amplification and overexpression during the limited replicative life span of normal human fibroblasts.
1985
Analysis of viral and somatic activations of the cHa-ras gene
1985
Biological and biochemical properties of human rasH genes mutated at codon 61
1986
Normal and activated ras oncogenes and their encoded products
1986
Expression of a Bacterial Gene in Mammalian Cells
1980 StandoutScienceNobel
Human Growth Hormone and Extracellular Domain of Its Receptor: Crystal Structure of the Complex
1992 StandoutScience
Harvey ras genes transform without mutant codons, apparently activated by truncation of a 5' exon (exon -1).
1986
Three human transforming genes are related to the viral ras oncogenes.
1983
The ras oncogene product p21 is not a regulatory component of adenylate cyclase
1985 Nature
Functional homology of mammalian and yeast RAS genes
1985
c-fos protein can induce cellular transformation: A novel mechanism of activation of a cellular oncogene
1984
Cloning of the gene and cDNA for mammalian β-adrenergic receptor and homology with rhodopsin
1986 StandoutNatureNobel
Transformation of NIH 3T3 cells by microinjection of Ha-ras p21 protein
1984 Nature
Neurexophilins Form a Conserved Family of Neuropeptide-Like Glycoproteins
1998 StandoutNobel
A Cytoplasmic Protein Stimulates Normal N- ras p21 GTPase, But Does Not Affect Oncogenic Mutants
1987 Science
Cellular transforming genes and oncogenesis
1984
Neurite outgrowth of PC12 cells is suppressed by wortmannin, a specific inhibitor of phosphatidylinositol 3-kinase.
1994
Post-translational processing of p21ras is two-step and involves carboxyl-methylation and carboxy-terminal proteolysis.
1989
Mechanism of activation of a human oncogene
1982 Nature
Acquisition of transforming properties by alternative point mutations within c-bas/has human proto-oncogene
1983 Nature
Photoaffinity labeling with GTP of viral p21 ras protein expressed in Escherichia coli
1984
Suppression of tumorigenicity in hybrids of normal and oncogene-transformed CHEF cells.
1985
Yeast and mammalian ras proteins have conserved biochemical properties
1985 Nature
Genetic analysis of yeast RAS1 and RAS2 genes
1984
Addiction Modules and Programmed Cell Death and Antideath in Bacterial Cultures
1999
Identification of multiple extracellular signal-regulated kinases (ERKs) with antipeptide antibodies.
1991
Comparative biochemical properties of normal and activated human ras p21 protein
1984 Nature
The Molecular Genetics of Cancer
1987 StandoutScienceNobel
Netrin-G1: a Novel Glycosyl Phosphatidylinositol-Linked Mammalian Netrin That Is Functionally Divergent from Classical Netrins
2000 StandoutNobel
Establishment of two rabbit mammary epithelial cell lines with distinct oncogenic potential and differentiated phenotype after microinjection of transforming genes.
1986
Human EJ bladder carcinoma oncogene is homologue of Harvey sarcoma virus ras gene
1982 Nature
Dominant inhibitory Ras mutants selectively inhibit the activity of either cellular or oncogenic Ras.
1991
The product of ras is a GTPase and the T24 oncogenic mutant is deficient in this activity
1984 Nature
Carcinogen-specific mutation and amplification of Ha-ras during mouse skin carcinogenesis
1986 Nature
Tyrosine Kinase Receptor with Extensive Homology to EGF Receptor Shares Chromosomal Location with neu Oncogene
1985 StandoutScience
Suppression of tumorigenicity with continued expression of the c-Ha-ras oncogene in EJ bladder carcinoma-human fibroblast hybrid cells.
1986
Activation of the T24 bladder carcinoma transforming gene is linked to a single amino acid change
1982 Nature
Protection from Oxidative Stress–Induced Apoptosis in Cortical Neuronal Cultures by Iron Chelators Is Associated with Enhanced DNA Binding of Hypoxia-Inducible Factor-1 and ATF-1/CREB and Increased Expression of Glycolytic Enzymes, p21waf1/cip1, and Erythropoietin
1999 StandoutNobel
An Insulin-Stimulated Protein Kinase Similar to Yeast Kinases Involved in Cell Cycle Control
1990 Science
Mutagens, oncogenes and cancer
1986
Identification of transforming gene in two human sarcoma cell lines as a new member of the ras gene family located on chromosome 1
1983 Nature
Oncogene v-src transforms and establishes embryonic rodent fibroblasts but not diploid human fibroblasts.
1988 StandoutNobel
Activation of c-Ha-ras-1 proto-oncogene by in vitro modification with a chemical carcinogen, benzo(a)pyrene diol-epoxide
1984 Nature
The protein cofactor necessary for ADP-ribosylation of Gs by cholera toxin is itself a GTP binding protein.
1986 StandoutNobel
Transient reversion of ras oncogene-induced cell transformation by antibodies specific for amino acid 12 of ras protein
1985 Nature
Characterization of two members of the rho gene family from the yeast Saccharomyces cerevisiae.
1987 StandoutNobel
Harvey murine sarcoma virus p21 ras protein: biological and biochemical significance of the cysteine nearest the carboxy terminus.
1984
The HL-60 transforming sequence: A ras oncogene coexisting with altered myc genes in hematopoietic tumors
1983
Structure and sequence of the cellular gene homologous to the RSV src gene and the mechanism for generating the transforming virus
1983
Phylogenetic Perspectives in Innate Immunity
1999 StandoutScienceNobel
Developmental regulation of a dictyostelium gene encoding a protein homologous to mammalian ras protein
1984
RAS proteins can induce meiosis in xenopus oocytes
1985
Nucleotide sequence of bacteriophage G4 DNA
1978 StandoutNature
Microinjection of the oncogene form of the human H-ras (t-24) protein results in rapid proliferation of quiescent cells
1984
Identification of a provirally activated c-Ha-ras oncogene in an avian nephroblastoma via a novel procedure: cDNA cloning of a chimaeric viral-host transcript.
1986
Behavior of myc and ras oncogenes in transformation of rat embryo fibroblasts.
1986
Resistance of human cells to tumorigenesis induced by cloned transforming genes.
1983
LPS-binding proteins and receptors
1998
Molecular cloning and sequence analysis of a ras gene from Schizosaccharomyces pombe.
1985
The human c-Ha-ras2 is a processed pseudogene inactivated by numerous base substitutions
1984
A cellular oncogene is translocated to the Philadelphia chromosome in chronic myelocytic leukaemia
1982 Nature
A method to detect and characterize point mutations in transcribed genes: amplification and overexpression of the mutant c-Ki-ras allele in human tumor cells.
1985
Works of Mark E. Furth being referenced
Lambda DNA Replication
1983
Activated N-ras controls the transformed phenotype of HT1080 human fibrosarcoma cells
1987
trkB encodes a functional receptor for brain-derived neurotrophic factor and neurotrophin-3 but not nerve growth factor
1991
NT-3, BDNF, and NGF in the developing rat nervous system: Parallel as well as reciprocal patterns of expression
1990
Isolation of amniotic stem cell lines with potential for therapy
2007
Monoclonal antibodies to the transformation-specific glycoprotein encoded by the feline retroviral oncogene v-fms
1982
Expression of ras proto-oncogene proteins in normal human tissues.
1987
Physical Structure of the Replication Origin of Bacteriophage Lambda
1977 Science
Mouse cells contain two distinct ras gene mRNA species that can be translated into a p21 onc protein.
1982
Phorbol ester- and protein kinase C-mediated phosphorylation of the cellular Kirsten ras gene product.
1987
Transforming ras genes from human melanoma: a manifestation of tumour heterogeneity?
1984 Nature
Tumorigenic transformation of mammalian cells induced by a normal human gene homologous to the oncogene of Harvey murine sarcoma virus
1982 Nature
Neurotrophin-3: a Neurotrophic Factor Related to NGF and BDNF
1990 Science
The Receptor for Ciliary Neurotrophic Factor
1991 Science
Analysis of the transforming potential of the human H-ras gene by random mutagenesis.
1984
Monoclonal antibodies to the p21 products of the transforming gene of Harvey murine sarcoma virus and of the cellular ras gene family
1982