Citation Impact
Citing Papers
Pathophysiology of Migraine: A Disorder of Sensory Processing
2017 Standout
Obesity and Metabolic Syndrome in Circadian Clock Mutant Mice
2005 StandoutScience
3,4-Methylenedioxymethamphetamine (MDMA) as a Unique Model of Serotonin Receptor Function and Serotonin-Dopamine Interactions
2001
Hox3 genes coordinate mechanisms of genetic suppression and activation in the generation of branchial and somatic motoneurons
2003 StandoutNobel
Multi-target strategies for the improved treatment of depressive states: Conceptual foundations and neuronal substrates, drug discovery and therapeutic application
2006
Antibodies to the GABAB receptor in limbic encephalitis with seizures: case series and characterisation of the antigen
2009 Standout
Functional Neuroimaging of Anxiety: A Meta-Analysis of Emotional Processing in PTSD, Social Anxiety Disorder, and Specific Phobia
2007 Standout
A Neurotrophic Model for Stress-Related Mood Disorders
2006 Standout
Serotonergic regulation of mRNA expression of Arc, an immediate early gene selectively localized at neuronal dendrites
2000
Genetic variation in cortico-amygdala serotonin function and risk for stress-related disease
2008
Merkel Cells Activate Sensory Neural Pathways through Adrenergic Synapses
2018 StandoutNobel
Contribution of 5-HT2Receptor Subtypes to Sleep–Wakefulness and Respiratory Control, and Functional Adaptations in Knock-Out Mice Lacking 5-HT2AReceptors
2005
Orexin A (hypocretin 1) injected into hypothalamic paraventricular nucleus and spontaneous physical activity in rats
2004
NeuPSIG guidelines on neuropathic pain assessment
2010 Standout
5-HT2A and 5-HT2C Receptors Exert Opposing Effects on Locomotor Activity in Mice
2009
Mechanisms and Functional Implications of Adult Neurogenesis
2008 Standout
Distribution of serotonin 5-HT2C receptors in the ventral tegmental area
2007
Effects of psilocybin on hippocampal neurogenesis and extinction of trace fear conditioning
2013
Neural mechanism underlying acupuncture analgesia
2008 Standout
Molecular, pharmacological and functional diversity of 5-HT receptors
2002 Standout
Serotonin-Induced Increases in Adult Cell Proliferation and Neurogenesis are Mediated Through Different and Common 5-HT Receptor Subtypes in the Dentate Gyrus and the Subventricular Zone
2003
Sex Differences in the Effects of Acute and Chronic Stress and Recovery after Long-Term Stress on Stress-Related Brain Regions of Rats
2008
Functional study of rat 5‐HT2A receptors using antisense oligonucleotides
2003
Descending control of pain
2002 Standout
Hypocretin/orexin and energy expenditure
2010
Promotion of sleep by targeting the orexin system in rats, dogs and humans
2007
Physiology and Neurobiology of Stress and Adaptation: Central Role of the Brain
2007 Standout
In Vivo Modulation of the Activity of Pyramidal Neurons in the Rat Medial Prefrontal Cortex by 5-HT2A Receptors: Relationship to Thalamocortical Afferents
2003
Effects of baseline anxiety on response to kindling of the right medial amygdala
2000
Mechanical, thermal and formalin-induced nociception is differentially altered in 5-HT1A−/−, 5-HT1B−/−, 5-HT2A−/−, 5-HT3A−/− and 5-HTT−/− knock-out male mice
2007 StandoutNobel
Network pharmacology: the next paradigm in drug discovery
2008 Standout
Impulsivity, Compulsivity, and Top-Down Cognitive Control
2011 Standout
The use of the elevated plus maze as an assay of anxiety-related behavior in rodents
2007 Standout
Locomotor networks are targets of modulation by sensory transient receptor potential vanilloid 1 and transient receptor potential melastatin 8 channels
2009 StandoutNobel
5-HT2A receptor or α1-adrenoceptor activation induces excitatory postsynaptic currents in layer V pyramidal cells of the medial prefrontal cortex
1999
Psychedelics
2016 Standout
Agonist-directed trafficking of signalling at serotonin 5-HT2A, 5-HT2B and 5-HT2C-VSV receptors mediated Gq/11 activation and calcium mobilisation in CHO cells
2008
Interaction of Serotonin 5-Hydroxytryptamine Type 2C Receptors with PDZ10 of the Multi-PDZ Domain Protein MUPP1
2001
The Pharmacology and Clinical Pharmacology of 3,4-Methylenedioxymethamphetamine (MDMA, “Ecstasy”)
2003 Standout
The Serotonin Signaling System: From Basic Understanding To Drug Development for Functional GI Disorders
2007 Standout
CRE/CREB-Driven Up-Regulation of Gene Expression by Chronic Social Stress in CRE-Luciferase Transgenic Mice: Reversal by Antidepressant Treatment
2007
Serotonergic innervation of the amygdala: targets, receptors, and implications for stress and anxiety
2013
Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies
2013 Standout
Therapeutic potential of β-arrestin- and G protein-biased agonists
2010 StandoutNobel
Effects of activation and blockade of 5-HT2A/2C receptors in the dorsal raphe nucleus on sleep and waking in the rat
2006
Novelty and Anxiolytic Drugs Dissociate Two Components of Hippocampal Theta in Behaving Rats
2013 StandoutNobel
Interaction between the Corticotropin-Releasing Factor System and Hypocretins (Orexins): A Novel Circuit Mediating Stress Response
2004
Antinociceptive effect of peripheral serotonin 5-HT2B receptor activation on neuropathic pain
2012
Stimulation of 5‐hydroxytryptamine (5‐HT2C) receptors in the ventrotegmental area inhibits stress‐induced but not basal dopamine release in the rat prefrontal cortex
2002
Effects of the serotonin 5-HT2A/2C receptor agonist DOI and of the selective 5-HT2A or 5-HT2C receptor antagonists EMD 281014 and SB-243213, respectively, on sleep and waking in the rat
2006
Stress signalling pathways that impair prefrontal cortex structure and function
2009 Standout
The Serotonin Syndrome
2005 Standout
The selective serotonin (5-HT)1A receptor ligand, S15535, displays anxiolytic-like effects in the social interaction and Vogel models and suppresses dialysate levels of 5-HT in the dorsal hippocampus of freely-moving rats
2000
Multiplicity of mechanisms of serotonin receptor signal transduction
2001
Correlation between the fighting rates of REM sleep-deprived rats and susceptibility to the ‘wild running’ of audiogenic seizures
2002
Stress, Depression, and Neuroplasticity: A Convergence of Mechanisms
2007
Pharmacological Studies of the Acute Effects of (+)-3,4-Methylenedioxymethamphetamine on Locomotor Activity, Role of 5-HT1B/1D and 5-HT2 Receptors
2002
G Protein-coupled Receptor Kinase 5 Regulates β1-Adrenergic Receptor Association with PSD-95
2002 StandoutNobel
Genetic and Pharmacological Evidence of a Role for GABAB Receptors in the Modulation of Anxiety- and Antidepressant-Like Behavior
2004
A review of central 5-HT receptors and their function
1999 Standout
Major Depressive Disorder
2008 Standout
Role of Striatal Serotonin2A and Serotonin2C Receptor Subtypes in the Control of In Vivo Dopamine Outflow in the Rat Striatum
2000
The neural basis of psychedelic action
2022 Standout
Dissociable Effects of Selective 5-HT2A and 5-HT2C Receptor Antagonists on Serial Spatial Reversal Learning in Rats
2007
Social deprivation stress is a triggering factor for the emergence of anxiety- and depression-like behaviours and leads to reduced brain BDNF levels in C57BL/6J mice
2011
Small molecule drug screening in Drosophila identifies the 5HT2A receptor as a feeding modulation target
2013 Standout
Serotonin controlling feeding and satiety
2014
Implication of 5-HT2A subtype receptors in DOI activity in the four-plates test–retest paradigm in mice
2005
Enantioselective synthesis of almorexant via iridium-catalysed intramolecular allylic amidation
2013 StandoutNobel
Serotonin, tryptophan metabolism and the brain-gut-microbiome axis
2014 Standout
Orexin Receptor Antagonists: A New Concept In CNS Disorders?
2010
Ethological and temporal analyses of anxiety-like behavior: The elevated plus-maze model 20 years on
2005
Serotonin and decision making processes
2011
Indoleamine and the phenethylamine hallucinogens: mechanisms of psychotomimetic action
1998
Neuronal localization of the 5-HT2 receptor family in the amygdaloid complex
2014
Orexins and appetite regulation
2002
Gut Microbiota Regulation of Tryptophan Metabolism in Health and Disease
2018 Standout
The Novel Melatonin Agonist Agomelatine (S20098) Is an Antagonist at 5-Hydroxytryptamine2C Receptors, Blockade of Which Enhances the Activity of Frontocortical Dopaminergic and Adrenergic Pathways
2003
Endocannabinoid-Mediated Control of Synaptic Transmission
2009
Increased cortical expression of the orexin-1 receptor following permanent middle cerebral artery occlusion in the rat
2002
Behavioural and hypothalamic molecular effects of the anti-cancer agent cisplatin in the rat: A model of chemotherapy-related malaise?
2006 StandoutNobel
Ghrelin: Structure and Function
2005 Standout
Novel 5-HT1A/1B/1D receptors antagonists with potent 5-HT reuptake inhibitory activity
2008
Endogenous serotonin and serotonin2Creceptors are involved in the ability of M100907 to suppress cortical glutamate release induced by NMDA receptor blockade
2008
The molecular neurobiology of depression
2008 StandoutNature
Effects of systemic and intra-nucleus accumbens 5-HT2C receptor compounds on ventral tegmental area self-stimulation thresholds in rats
2008
Anxiolytic properties of agomelatine, an antidepressant with melatoninergic and serotonergic properties: role of 5-HT2C receptor blockade
2004
Orexin activation counteracts decreases in nonexercise activity thermogenesis (NEAT) caused by high-fat diet
2017 Standout
Limitations in anti-obesity drug development: the critical role of hunger-promoting neurons
2012
Cross-talk between 5-Hydroxytryptamine Receptors in a Serotonergic Cell Line
1998
Pet-1 ETS Gene Plays a Critical Role in 5-HT Neuron Development and Is Required for Normal Anxiety-like and Aggressive Behavior
2003
Solid-Phase Intramolecular N-Acyliminium Pictet−Spengler Reactions as Crossroads to Scaffold Diversity
2004 StandoutNobel
ADULT NEUROGENESIS IN THE MAMMALIAN CENTRAL NERVOUS SYSTEM
2005 Standout
(±)-3,4-Methylenedioxymethamphetamine (MDMA, ‘Ecstasy’) increases social interaction in rats
2000
Marine Indole Alkaloids: Potential New Drug Leads for the Control of Depression and Anxiety
2010 Standout
The Medicinal Chemist’s Toolbox: An Analysis of Reactions Used in the Pursuit of Drug Candidates
2011 Standout
Effects of centrally administered anxiolytic compounds in animal models of anxiety
1999
Stressor Controllability, Anxiety, and Serotonin
1998
Translational Findings on Brain-Derived Neurotrophic Factor and Anxiety: Contributions from Basic Research to Clinical Practice
2013 Standout
Control of Serotonergic Function in Medial Prefrontal Cortex by Serotonin-2A Receptors through a Glutamate-Dependent Mechanism
2001
Regulation of G Protein–Coupled Receptor Signaling by Scaffold Proteins
2002 StandoutNobel
Combination therapy in combating cancer
2017 Standout
Biomedical Application of Orexin/Hypocretin Receptor Ligands in Neuroscience
2009
Head‐twitch response in rodents induced by the hallucinogen 2,5‐dimethoxy‐4‐iodoamphetamine: a comprehensive history, a re‐evaluation of mechanisms, and its utility as a model
2012
Serotonin Receptors
2008
Rab3B protein is required for long-term depression of hippocampal inhibitory synapses and for normal reversal learning
2011 StandoutNobel
Cellular and subcellular distribution of the serotonin 5-HT2A receptor in the central nervous system of adult rat
1999
Modulation of dopamine release by striatal 5‐HT2C receptors
2005
Medicinal Chemistry Driven Approaches Toward Novel and Selective Serotonin 5-HT6Receptor Ligands
2004
Sertoli-Sertoli and Sertoli-Germ Cell Interactions and Their Significance in Germ Cell Movement in the Seminiferous Epithelium during Spermatogenesis
2004 Standout
The Role of Hypocretins (Orexins) in Sleep Regulation and Narcolepsy
2002
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
Higher-End Serotonin Receptors: 5-HT5, 5-HT6, and 5-HT7
2003
Physiology of Microglia
2011 Standout
Hallucinogens
2004 Standout
Works of Mark Duxon being referenced
Social threat and novel cage stress-induced sustained extracellular-regulated kinase1/2 (ERK1/2) phosphorylation but differential modulation of brain-derived neurotrophic factor (BDNF) expression in the hippocampus of NMRI mice
2005
Repeated sensory contact with aggressive mice rapidly leads to an anticipatory increase in core body temperature and physical activity that precedes the onset of aversive responding
2004
Pharmacological profile of SB-357134: A potent, selective, brain penetrant, and orally active 5-HT6 receptor antagonist
2002
Activation of 5-HT 2B Receptors in the Medial Amygdala causes Anxiolysis in the Social Interaction Test in the Rat
1997
Evidence that orexin-A-evoked grooming in the rat is mediated by orexin-1 (OX 1 ) receptors, with downstream 5-HT 2C receptor involvement
2001
Further evidence for the predictive validity of the unstable elevated exposed plus-maze, a behavioural model of extreme anxiety in rats: Differential effects of fluoxetine and chlordiazepoxide
2002
SB-649915-B, a Novel 5-HT1A/B Autoreceptor Antagonist and Serotonin Reuptake Inhibitor, is Anxiolytic and Displays Fast Onset Activity in the Rat High Light Social Interaction Test
2007
5-HT 2C receptor mediation of unconditioned escape behaviour in the unstable elevated exposed plus maze
2002
Ethopharmacological analysis of the unstable elevated exposed plus maze, a novel model of extreme anxiety: predictive validity and sensitivity to anxiogenic agents
2002
Immunohistochemical localisation of the 5-HT2C receptor protein in the rat CNS
2000
Effect of SB-243213, a selective 5-HT2C receptor antagonist, on the rat sleep profile
2002
Central C-Fos Expression Following 20kHz/Ultrasound Induced Defence Behaviour in the Rat
1997
Evidence for accelerated desensitisation of 5-HT2C receptors following combined treatment with fluoxetine and the 5-HT1A receptor antagonist, WAY 100,635, in the rat
2000
Latency to paroxetine‐induced anxiolysis in the rat is reduced by co‐administration of the 5‐HT1A receptor antagonist WAY100635
2000
Evidence for expression of the 5-hydroxytryptamine-2B receptor protein in the rat central nervous system
1997
Evidence implicating a role for orexin-1 receptor modulation of paradoxical sleep in the rat
2003