Citation Impact
Citing Papers
Integrative genomic and functional analyses reveal neuronal subtype differentiation bias in human embryonic stem cell lines
2007 StandoutNobel
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
2005 Standout
Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival
2005
Keeping G Proteins at Bay: A Complex Between G Protein-Coupled Receptor Kinase 2 and Gßγ
2003 StandoutScienceNobel
Autoregulation of E-cadherin expression by cadherin–cadherin interactions
2003
Functional Cross-talk between β-Catenin and NFκB Signaling Pathways in Colonic Crypts of Mice in Response to Progastrin
2009
Comprehensive genomic characterization of head and neck squamous cell carcinomas
2015 StandoutNature
Molecular mechanisms underlying ErbB2/HER2 action in breast cancer
2000
Geldanamycin abrogates ErbB2 association with proteasome-resistant beta-catenin in melanoma cells, increases beta-catenin-E-cadherin association, and decreases beta-catenin-sensitive transcription.
2001
Herceptin: mechanisms of action and resistance
2005
Hallmarks of Cancer: The Next Generation
2011 Standout
Stem cells: the intestinal stem cell as a paradigm
2000
Small-molecule antagonists of the oncogenic Tcf/β-catenin protein complex
2004
Caught up in a Wnt storm: Wnt signaling in cancer
2003
Angiogenesis: A Team Effort Coordinated by Notch
2009
Structural basis of the Axin–adenomatous polyposis coli interaction
2000
A novel role of IKKα in the mediation of UVB-induced G0/G1 cell cycle arrest response by suppressing Cyclin D1 expression
2010
Secreted Frizzled-related Protein-1 Binds Directly to Wingless and Is a Biphasic Modulator of Wnt Signaling
2000
Stem cells, cancer, and cancer stem cells
2001 StandoutNature
GSK3 takes centre stage more than 20 years after its discovery
2001
Wnt Signaling Regulates B Lymphocyte Proliferation through a LEF-1 Dependent Mechanism
2000
The β-Catenin/TCF-4 Complex Imposes a Crypt Progenitor Phenotype on Colorectal Cancer Cells
2002 Standout
Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts
2010 StandoutNature
Oncogenic kinase signalling
2001 StandoutNature
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
The cancer glycocalyx mechanically primes integrin-mediated growth and survival
2014 StandoutNatureNobel
Downregulation of caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of β-catenin, and enhanced tumor cell invasion
2003
Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals
2009 StandoutNature
Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
2006 StandoutNobel
The Crystal Structure of the β-Catenin/ICAT Complex Reveals the Inhibitory Mechanism of ICAT
2002
Proliferation, cell cycle and apoptosis in cancer
2001 StandoutNature
The p300/CBP acetyltransferases function as transcriptional coactivators of beta-catenin in vertebrates
2000
The ground state of embryonic stem cell self-renewal
2008 StandoutNature
Wnt proteins are lipid-modified and can act as stem cell growth factors
2003 StandoutNature
The NF-κB-independent functions of IKK subunits in immunity and cancer
2009
Synergistic Activation of the Wnt Signaling Pathway by Dvl and Casein Kinase Iε
2001
The Hallmarks of Cancer
2000 Standout
Oncogenic pathway signatures in human cancers as a guide to targeted therapies
2005 StandoutNature
IKKα stabilizes cytosolic β-catenin by inhibiting both canonical and non-canonical degradation pathways
2006
Wnt signaling in the intestinal epithelium: from endoderm to cancer
2005
NF-κB inhibition delays DNA damage–induced senescence and aging in mice
2012
Regulation of β-Catenin Function by the IκB Kinases
2001
Regulation of p53 tumour suppressor target gene expression by the p52 NF‐κB subunit
2006
The AKT/IκB kinase pathway promotes angiogenic/metastatic gene expression in colorectal cancer by activating nuclear factor-κB and β-catenin
2004
Nuclear factor-κB in cancer development and progression
2006 StandoutNature
Fibronectin, integrins, and growth control
2001
Functional roles of Akt signaling in mouse skin tumorigenesis
2002
E-cadherin, β-catenin, and ZEB1 in malignant progression of cancer
2009
Nrarp Coordinates Endothelial Notch and Wnt Signaling to Control Vessel Density in Angiogenesis
2009
Ajuba negatively regulates the Wnt signaling pathway by promoting GSK-3β-mediated phosphorylation of β-catenin
2007
Identification of a Wnt/Dvl/β-Catenin → Pitx2 Pathway Mediating Cell-Type-Specific Proliferation during Development
2002
The c-Myc target gene network
2006
The ABC of APC
2001
Genetic regulators of large-scale transcriptional signatures in cancer
2006
Differential interaction of plakoglobin and β-catenin with the ubiquitin-proteasome system
2000 StandoutNobel
A role for Wnt signalling in self-renewal of haematopoietic stem cells
2003 StandoutNature
Immunity, Inflammation, and Cancer
2010 Standout
NF-κB and IKK as therapeutic targets in cancer
2006 Standout
Migrating cancer stem cells — an integrated concept of malignant tumour progression
2005
An oncogenic KRAS2 expression signature identified by cross-species gene-expression analysis
2004
Cancer immunotherapy comes of age
2011 StandoutNature
Reactive oxygen species have a causal role in multiple forms of insulin resistance
2006 StandoutNature
Off the beaten pathway: the complex cross talk between Notch and NF-κB
2007
NF-κB and cell-cycle regulation: the cyclin connection
2001
IκB kinase complexes: gateways to NF-κB activation and transcription
2006
Crosstalk in NF-κB signaling pathways
2011 Standout
The Hallmarks of Aging
2013 Standout
Chibby, a nuclear β-catenin-associated antagonist of the Wnt/Wingless pathway
2003 Nature
Integration of Notch and Wnt signaling in hematopoietic stem cell maintenance
2005
Cyclin D1 Is Not an Immediate Target of β-Catenin following Apc Loss in the Intestine
2005
Ras, PI(3)K and mTOR signalling controls tumour cell growth
2006 StandoutNature
IKKα Regulates Estrogen-induced Cell Cycle Progression by Modulating E2F1 Expression
2006
Wnt signalling in stem cells and cancer
2005 StandoutNature
Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis
2010 StandoutNature
Integrins
2002 Standout
Regulation of growth factor signaling and cell cycle progression by cell adhesion and adhesion-dependent changes in cellular tension
2005
IκB Kinase α Regulates Subcellular Distribution and Turnover of Cyclin D1 by Phosphorylation
2005
Molecular mechanisms and clinical applications of angiogenesis
2011 StandoutNature
Glucocorticoids Inhibit the Transcriptional Activity of LEF/TCF in Differentiating Osteoblasts in a Glycogen Synthase Kinase-3β-dependent and -independent Manner
2004
Crypt stem cells as the cells-of-origin of intestinal cancer
2008 StandoutNature
Identification of stem cells in small intestine and colon by marker gene Lgr5
2007 StandoutNature
Role of YAP/TAZ in mechanotransduction
2011 StandoutNature
The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells
2008 Standout
Human ES cell-derived neural rosettes reveal a functionally distinct early neural stem cell stage
2008
Integrating cell-signalling pathways with NF-κB and IKK function
2006 Standout
Pathway-specific tumor suppression
2002
Convergence of Wnt, ß-Catenin, and Cadherin Pathways
2004 StandoutScience
Presenilin 1 Negatively Regulates β-Catenin/T Cell Factor/Lymphoid Enhancer Factor-1 Signaling Independently of β-Amyloid Precursor Protein and Notch Processing
2001
Mice with mutations of Dock7 have generalized hypopigmentation and white-spotting but show normal neurological function
2009 StandoutNobel
Differential regulation of midbrain dopaminergic neuron development by Wnt-1, Wnt-3a, and Wnt-5a
2003
Oncogenic Mutants of RON and MET Receptor Tyrosine Kinases Cause Activation of the β-Catenin Pathway
2001
Wnt signaling and cancer
2000 Standout
The beta-catenin binding domain of adenomatous polyposis coli is sufficient for tumor suppression.
2000
WISP-1 is a Wnt-1- and β-catenin-responsive oncogene
2000
Exploring and Engineering the Cell Surface Interface
2005 StandoutScience
Organogenesis in a dish: Modeling development and disease using organoid technologies
2014 StandoutScience
β-Arrestin1 modulates lymphoid enhancer factor transcriptional activity through interaction with phosphorylated dishevelled proteins
2001 StandoutNobel
Integrin Signaling
1999 StandoutScience
WISP-1 is a Wnt-1- and beta-catenin-responsive oncogene.
2000
Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells
2012 StandoutNobel
Down-regulation of beta-catenin TCF signaling is linked to colonic epithelial cell differentiation.
2001
Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation
1999 Standout
Impaired mammary gland and lymphoid development caused by inducible expression of Axin in transgenic mice
2001
p53 Represses Cyclin D1 Transcription through Down Regulation of Bcl-3 and Inducing Increased Association of the p52 NF-κB Subunit with Histone Deacetylase 1
2003
A mitogen gradient of dorsal midline Wnts organizes growth in the CNS
2002
Cancer Genome Landscapes
2013 StandoutScience
THE WNT SIGNALING PATHWAY IN DEVELOPMENT AND DISEASE
2004 Standout
Hippocampus development and generation of dentate gyrus granule cells is regulated by LEF1
2000
RHO GTPASES: Biochemistry and Biology
2005 Standout
Inhibition of the Wnt Signaling Pathway by Idax, a Novel Dvl-Binding Protein
2001
Wnt5aandWnt5bexhibit distinct activities in coordinating chondrocyte proliferation and differentiation
2003
Integrins and cell proliferation
2001
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
Regulation of S33/S37 phosphorylated β-catenin in normal and transformed cells
2002
Promotion of direct reprogramming by transformation-deficient Myc
2010 StandoutNobel
Up-regulation of the ectodermal-neural cortex 1 (ENC1) gene, a downstream target of the beta-catenin/T-cell factor complex, in colorectal carcinomas.
2001
Early onset of neoplasia in the prostate and skin of mice with tissue-specific deletion of Pten
2004 StandoutNobel
Expression of ΔNLef1 in mouse epidermis results in differentiation of hair follicles into squamous epidermal cysts and formation of skin tumours
2002
LEF-1 is crucial for neutrophil granulocytopoiesis and its expression is severely reduced in congenital neutropenia
2006 Standout
The Putative Oncoprotein Bcl-3 Induces Cyclin D1 To Stimulate G1 Transition
2001
Works of Mark D’Amico being referenced
Cyclin D1 Is Required for Transformation by Activated Neu and Is Induced through an E2F-Dependent Signaling Pathway
2000
Gene expression phenotypic models that predict the activity of oncogenic pathways
2003
DACH1 Inhibits Transforming Growth Factor-β Signaling through Binding Smad4
2003
Integration of Rac-dependent Regulation of Cyclin D1 Transcription through a Nuclear Factor-κB-dependent Pathway
1999
Activation of the cyclin D1 Gene by the E1A-associated Protein p300 through AP-1 Inhibits Cellular Apoptosis
1999
The cyclin D1 gene is a target of the β-catenin/LEF-1 pathway
1999 Standout
Flavopiridol and trastuzumab synergistically inhibit proliferation of breast cancer cells: association with selective cooperative inhibition of cyclin D1-dependent kinase and Akt signaling pathways.
2002
IKKα Regulates Mitogenic Signaling through Transcriptional Induction of Cyclin D1 via Tcf
2003