Citation Impact
Citing Papers
The 2.6 Angstrom Crystal Structure of a Human A 2A Adenosine Receptor Bound to an Antagonist
2008 StandoutScience
Cancer Exosomes Express CD39 and CD73, Which Suppress T Cells through Adenosine Production
2011
Mast Cells and Neutrophils Release IL-17 through Extracellular Trap Formation in Psoriasis
2011
RIPK3-Mediated Necroptosis Promotes Donor Kidney Inflammatory Injury and Reduces Allograft Survival
2013
A2A Adenosine Receptor May Allow Expansion of T Cells Lacking Effector Functions in Extracellular Adenosine-Rich Microenvironments
2009
FoxP3+ T regulatory cells in cancer: Prognostic biomarkers and therapeutic targets
2020
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
Re-establishing immunological self-tolerance in autoimmune disease
2012 StandoutNobel
A2B adenosine receptor dampens hypoxia-induced vascular leak
2007
Ischemia and reperfusion—from mechanism to translation
2011 Standout
Contribution of α2 receptor subtypes to nerve injury‐induced pain and its regulation by dexmedetomidine
2001
Innate IL-17-producing cells: the sentinels of the immune system
2010 Standout
Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance
2009 StandoutNature
Transcriptional control of adenosine signaling by hypoxia-inducible transcription factors during ischemic or inflammatory disease
2012
Acute Kidney Injury in Older Adults
2011
Cyclic AMP Represents a Crucial Component of Treg Cell-Mediated Immune Regulation
2016
Necroptosis and its role in inflammation
2015 StandoutNature
Adenosine Receptors in Health and Disease
2011
Alpha2A-adrenergic receptors are present in lower brainstem catecholaminergic and serotonergic neurons innervating spinal cord
1994
Oral Fingolimod or Intramuscular Interferon for Relapsing Multiple Sclerosis
2010 Standout
Pannexin 1 channels facilitate communication between T cells to restrict the severity of airway inflammation
2021
A Placebo-Controlled Trial of Oral Fingolimod in Relapsing Multiple Sclerosis
2010 Standout
Bidirectional modulation of nociception by GABA neurons in the dorsolateral pontine tegmentum that tonically inhibit spinally projecting noradrenergic A7 neurons
2000
Intestinal homeostasis and its breakdown in inflammatory bowel disease
2011 StandoutNature
The microbiota in adaptive immune homeostasis and disease
2016 StandoutNature
Cisplatin nephrotoxicity: Mechanisms and renoprotective strategies
2008 Standout
Update on Mechanisms of Ischemic Acute Kidney Injury
2006
Nucleotide signalling during inflammation
2014 StandoutNature
Finding a way out: lymphocyte egress from lymphoid organs
2007
Descending control of pain
2002 Standout
Acute Kidney Injury and Chronic Kidney Disease as Interconnected Syndromes
2014 Standout
Localization ofα2c-adrenergic receptor immunoreactivity in catecholaminergic neurons in the rat central nervous system
1998
Cell-type Specific Targeting of the α2c-Adrenoceptor
2000 StandoutNobel
Pro-resolving lipid mediators are leads for resolution physiology
2014 StandoutNature
Cholinergic agonists attenuate renal ischemia–reperfusion injury in rats
2008
The distribution and significance of CNS adrenoceptors examined with in situ hybridization
1996
Enhancement of tumor immunotherapy by deletion of the A2A adenosine receptor
2011
Long-term sequelae of acute kidney injury in the ICU
2012
Hallmarks of aging: An expanding universe
2023 Standout
Short and dysfunctional telomeres sensitize the kidneys to develop fibrosis
2021
Hypoxia and Inflammation
2011 Standout
Cellular pathophysiology of ischemic acute kidney injury
2011 Standout
Messengers without Borders
2013
Adenosine receptors as therapeutic targets
2006 Standout
Expression of α2‐adrenergic receptors in rat primary afferent neurones after peripheral nerve injury or inflammation
1999
Cisplatin-induced nephrotoxicity is mediated by tumor necrosis factor-α produced by renal parenchymal cells
2007
The interaction between ischemia–reperfusion and immune responses in the kidney
2009
Purinergic regulation of the immune system
2016
The role of Tregs and CD11c+ macrophages/dendritic cells in ischemic preconditioning of the kidney
2010
Foxp3+ regulatory T cells participate in repair of ischemic acute kidney injury
2009
α 2-Adrenergic receptor subtypes in rat dorsal root and superior cervical ganglion neurons
1997
Kidney ischemic preconditioning
2002
Macrophages contribute to the development of renal fibrosis following ischaemia/reperfusion-induced acute kidney injury
2007
Models of Lung Transplant Research: a consensus statement from the National Heart, Lung, and Blood Institute workshop
2017
Cisplatin-Induced Acute Renal Failure Is Associated with an Increase in the Cytokines Interleukin (IL)-1β, IL-18, IL-6, and Neutrophil Infiltration in the Kidney
2007
The inflammatory response to ischemic acute kidney injury: a result of the ‘right stuff’ in the ‘wrong place’?
2007
Gene targeting — homing in on α2-adrenoceptor-subtype function
1997 StandoutNobel
Immunocytochemical localization of an imidazoline receptor protein in the central nervous system
1998
Lymphocytes and ischemia-reperfusion injury
2008
Targeting the hypoxia-adenosinergic signaling pathway to improve the adoptive immunotherapy of cancer
2013
Distribution of ?2C-adrenergic receptor-like immunoreactivity in the rat central nervous system
1996
Two functionally distinct α2-adrenergic receptors regulate sympathetic neurotransmission
1999 StandoutNatureNobel
Chemical modulators of sphingosine-1-phosphate receptors as barrier-oriented therapeutic molecules
2009
Subcellular localization of α‐2A‐adrenergic receptors in the rat medial nucleus tractus solitarius: Regional targeting and relationship with catecholamine neurons
2001
Fractalkine receptor (CX3CR1) inhibition is protective against ischemic acute renal failure in mice
2007
Inflammatory cytokines in acute renal failure
2004
Management of Chronic Kidney Disease Patients in the Intensive Care Unit: Mixing Acute and Chronic Illness
2017 Standout
Recent Advances in the Pathophysiology of Ischemic Acute Renal Failure
2003
Distribution and regulation of α 2-adrenoceptors in rat dorsal root ganglia
2000
The blockade of immune checkpoints in cancer immunotherapy
2012 Standout
Major Depressive Disorder
2008 Standout
Adenosine receptors: therapeutic aspects for inflammatory and immune diseases
2008 Standout
Resolvins E1 and D1 inhibit interstitial fibrosis in the obstructed kidney via inhibition of local fibroblast proliferation
2012
Enabling Innovative Translational Research in Acute Kidney Injury
2011
Sphingosine 1-phosphate receptors in health and disease: Mechanistic insights from gene deletion studies and reverse pharmacology
2007
What We Talk About When We Talk About Fat
2014 Standout
Artificial Intelligence in Cardiology
2018 Standout
Progress and challenges in translating the biology of atherosclerosis
2011 StandoutNature
The innate immune response in ischemic acute kidney injury
2008
Expression of α2 adrenoceptors during rat brain development—I. α2A messenger RNA expression
1996
Dendritic cell metabolism
2014
EXPRESSION OF α 2 -ADRENERGIC RECEPTOR SUBTYPES IN THE MOUSE BRAIN: EVALUATION OF SPATIAL AND TEMPORAL INFORMATION IMPARTED BY 3 kb OF 5′ REGULATORY SEQUENCE FOR THE α 2A AR-RECEPTOR GENE IN TRANSGENIC ANIMALS
1996
The Reno-Vascular A2B Adenosine Receptor Protects the Kidney from Ischemia
2008
Receptor localization in the mammalian dorsal horn and primary afferent neurons
1997
Distinct Macrophage Phenotypes Contribute to Kidney Injury and Repair
2011
Synergistic interactions between two α 2-adrenoceptor agonists, dexmedetomidine and ST-91, in two substrains of Sprague–Dawley rats
2000
Identification of the CD4+ T cell as a major pathogenic factor in ischemic acute renal failure
2001
CD39/ENTPD1 Expression by CD4+Foxp3+ Regulatory T Cells Promotes Hepatic Metastatic Tumor Growth in Mice
2010
Interleukin-10 inhibits ischemic and cisplatin-induced acute renal injury
2001
Attenuating myocardial ischemia by targeting A2B adenosine receptors
2013
Alpha2A-adrenergic receptors are primarily presynaptic heteroreceptors in the C1 area of the rat rostral ventrolateral medulla
1999
Secukinumab in Plaque Psoriasis — Results of Two Phase 3 Trials
2014 Standout
Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages
2016 Standout
Adenosine as a Multi-Signalling Guardian Angel in Human Diseases: When, Where and How Does it Exert its Protective Effects?
2016
Genetic Alteration of α2C-Adrenoceptor Expression in Mice: Influence on Locomotor, Hypothermic, and Neurochemical Effects of Dexmedetomidine, a Subtype-Nonselective α2-Adrenoceptor Agonist
1997 StandoutNobel
In Vivo Gene Modification Elucidates Subtype-Specific Functions of α2-Adrenergic Receptors
2000
Tumor-infiltrating regulatory T cells as targets of cancer immunotherapy
2023 StandoutNobel
Differential Distribution of α2Aand α2CAdrenergic Receptor Immunoreactivity in the Rat Spinal Cord
1998
The Th17 Pathway and Inflammatory Diseases of the Intestines, Lungs, and Skin
2011
Adenosine: An Old Drug Newly Discovered
2009
The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)
2016 Standout
Immune cell regulation by autocrine purinergic signalling
2011
Immunometabolism governs dendritic cell and macrophage function
2015 Standout
ACTIONS OF ADENOSINE AT ITS RECEPTORS IN THE CNS: Insights from Knockouts and Drugs
2004
Clinical Implications of Extracellular HMGA1 in Breast Cancer
2019
Ultrastructural evidence for prominent postsynaptic localization of ?2C-adrenergic receptors in catecholaminergic dendrites in the rat nucleus locus coeruleus
1998
A2A receptor signaling promotes peripheral tolerance by inducing T-cell anergy and the generation of adaptive regulatory T cells
2007
Acetylcholine-Synthesizing T Cells Relay Neural Signals in a Vagus Nerve Circuit
2011 StandoutScience
Heterozygous α 2A -adrenergic receptor mice unveil unique therapeutic benefits of partial agonists
2002 StandoutNobel
Reduced expression of Na-K-2Cl cotransporter in medullary TAL in vitamin D-induced hypercalcemia in rats
2002
Decreased Capacity of Immune Cells to Cause Tissue Injury Mediates Kidney Ischemic Preconditioning
2006
Acute kidney injury: a springboard for progression in chronic kidney disease
2010
Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment
2018 StandoutNobel
A2B Adenosine Receptor Blockade Enhances Macrophage-Mediated Bacterial Phagocytosis and Improves Polymicrobial Sepsis Survival in Mice
2011
Identification of the CD4+ T cell as a major pathogenic factor in ischemic acute renal failure
2001
Chemotherapy induces enrichment of CD47 + /CD73 + /PDL1 + immune evasive triple-negative breast cancer cells
2018 StandoutNobel
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Development and Validation of an Acute Kidney Injury Risk Index for Patients Undergoing General Surgery
2009
Role of Interleukin 17 in Inflammation, Atherosclerosis, and Vascular Function in Apolipoprotein E–Deficient Mice
2011
The ectonucleotidases CD 39 and CD 73: Novel checkpoint inhibitor targets
2017
Distribution of ?2A-adrenergic receptor-like immunoreactivity in the rat central nervous system
1996
Cell death induced by acute renal injury: a perspective on the contributions of apoptosis and necrosis
2003
Endothelial Hypoxia-Inducible Factor-2α Is Required for the Maintenance of Airway Microvasculature
2019 StandoutNobel
In vivo gene modification elucidates subtype-specific functions of alpha(2)-adrenergic receptors.
2000
Both MC5r and A2Ar Are Required for Protective Regulatory Immunity in the Spleen of Post–Experimental Autoimmune Uveitis in Mice
2013
Molecular Approach to Adenosine Receptors: Receptor-Mediated Mechanisms of Tissue Protection
2001
Bradykinin B1 and B2 receptors both have protective roles in renal ischemia/reperfusion injury
2007 StandoutNobel
International Union of Pharmacology. XXV. Nomenclature and Classification of Adenosine Receptors
2001 Standout
A Metabolic Immune Checkpoint: Adenosine in Tumor Microenvironment
2016
Inflammation and metabolism in tissue repair and regeneration
2017 StandoutScience
Hypoxia-inducible factor 1 is required for remote ischemic preconditioning of the heart
2013 StandoutNobel
Aquaporins in the Kidney: From Molecules to Medicine
2002 StandoutNobel
Sepsis: Multiple Abnormalities, Heterogeneous Responses, and Evolving Understanding
2013
Adenosine and inflammation: CD39 and CD73 are critical mediators in LPS‐induced PMN trafficking into the lungs
2008
Potential Role of Regulatory T Cells in Reversing Obesity-Linked Insulin Resistance and Diabetic Nephropathy
2011
Gene targeting — homing in on α2-adrenoceptor-subtype function
1997 StandoutNobel
Atezolizumab and Nab-Paclitaxel in Advanced Triple-Negative Breast Cancer
2018 Standout
CD73 + regulatory T cells contribute to adenosine‐mediated resolution of acute lung injury
2013
Hypoxia-inducible factor 1 transcriptional activity in endothelial cells is required for acute phase cardioprotection induced by ischemic preconditioning
2012 StandoutNobel
Works of Mark D. Okusa being referenced
NKT Cell Activation Mediates Neutrophil IFN-γ Production and Renal Ischemia-Reperfusion Injury
2007
Blocking the immune response in ischemic acute kidney injury: the role of adenosine 2A agonists
2006
The Immunosuppressive Role of Adenosine A2A Receptors in Ischemia Reperfusion Injury and Islet Transplantation
2012
The chemokine receptors CCR2 and CX3CR1 mediate monocyte/macrophage trafficking in kidney ischemia–reperfusion injury
2008
Synthesis and biological evaluation of γ-aminophosphonates as potent, subtype-selective sphingosine 1-phosphate receptor agonists and antagonists
2006
Sphingosine-1-phosphate receptors: Biology and therapeutic potential in kidney disease
2008
Renal protection from ischemia mediated by A2A adenosine receptors on bone marrow–derived cells
2003
Regulatory T cells contribute to the protective effect of ischemic preconditioning in the kidney
2010
Dangers Within
2011
Acute Kidney Injury Associated with Cardiac Surgery
2005
Compartmentalization of neutrophils in the kidney and lung following acute ischemic kidney injury
2009
Regulatory T Cells Suppress Innate Immunity in Kidney Ischemia-Reperfusion Injury
2009
Bridging Translation by Improving Preclinical Study Design in AKI
2015
Immunohistochemical localization ofα2a-adrenergic receptors in catecholaminergic and other brainstem neurons in the rat
1993
Selective sphingosine 1-phosphate 1 receptor activation reduces ischemia-reperfusion injury in mouse kidney
2006
Natural Killer T Cell–derived IL-17 Mediates Lung Ischemia–Reperfusion Injury
2011
Pharmacologic Treatment of Acute Kidney Injury
2007
Selective blockade of lysophosphatidic acid LPA3receptors reduces murine renal ischemia-reperfusion injury
2003
Adenosine A2Areceptor activation attenuates inflammation and injury in diabetic nephropathy
2005
Anti-inflammatory effect of fibrate protects from cisplatin-induced ARF
2005
Dendritic cells tolerized with adenosine A2AR agonist attenuate acute kidney injury
2012
Autocrine Adenosine Signaling Promotes Regulatory T Cell–Mediated Renal Protection
2012
The Inflammatory Cascade in Acute Ischemic Renal Failure
2002
Protection from ischemic liver injury by activation of A2Aadenosine receptors during reperfusion: inhibition of chemokine induction
2004
Inflammation in Acute Kidney Injury
2008
IL-17 produced by neutrophils regulates IFN-γ–mediated neutrophil migration in mouse kidney ischemia-reperfusion injury
2009
Renal ischemia-reperfusion injury and adenosine 2A receptor-mediated tissue protection: role of macrophages
2004
Selective A2Aadenosine receptor activation reduces ischemia-reperfusion injury in rat kidney
1999
Luminal calcium regulates potassium transport by the renal distal tubule
1990
AKI
2013
A2A Adenosine Receptors on Bone Marrow-Derived Cells Protect Liver from Ischemia-Reperfusion Injury
2005
A2Aadenosine receptor-mediated inhibition of renal injury and neutrophil adhesion
2000
Effect of Na-channel blockers and lumen Ca on K secretion by rat renal distal tubule
1991
Renal Ischemia-Reperfusion Injury and Adenosine 2A Receptor-Mediated Tissue Protection: The Role of CD4+ T Cells and IFN-γ
2006
Activation of Adenosine 2A Receptors Attenuates Allograft Rejection and Alloantigen Recognition
2007
A2Aadenosine receptor: a novel therapeutic target in renal disease
2002
Epithelial and Endothelial Pannexin1 Channels Mediate AKI
2018
Sphingosine Kinase 2 Deficiency Attenuates Kidney Fibrosis via IFN-γ
2016