Citation Impact
Citing Papers
X-linked cholestasis in mouse due to mutations of the P4-ATPase ATP11C
2011 StandoutNobel
The Organization, Promoter Analysis, and Expression of the Human PPARγ Gene
1997 Standout
PPARalpha and PPARgamma activators direct a distinct tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene.
1996
A Novel Subtype of the Prostacyclin Receptor Expressed in the Central Nervous System
1996 StandoutNobel
Functional Antagonism between CCAAT/Enhancer Binding Protein-α and Peroxisome Proliferator-activated Receptor-γ on the Leptin Promoter
1997
PPARγ3 mRNA: a distinct PPARγ mRNA subtype transcribed from an independent promoter
1998
Activators of the nuclear receptor PPARγ enhance colon polyp formation
1998
Retinoic acid receptors: From molecular mechanisms to cancer therapy
2014
Inflammation and metabolic disorders
2006 StandoutNature
The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation
1998 StandoutNature
Insulin- and Mitogen-activated Protein Kinase-mediated Phosphorylation and Activation of Peroxisome Proliferator-activated Receptor γ
1996
Subcutaneous or visceral adipose tissue expression of the PPARγ gene is not altered in the fatty ( ) Zucker rat
1998
PPARγ: a Nuclear Regulator of Metabolism, Differentiation, and Cell Growth
2001
Homozygosity of the Pro12Ala variant of the peroxisome proliferation-activated receptor-γ2 (PPAR-γ2): divergent modulating effects on body mass index in obese and lean Caucasian men
1999
Modulation of ion-channel function by G-protein-coupled receptors
1994
Thiazolidinediones block tumor necrosis factor-alpha-induced inhibition of insulin signaling.
1997
Peroxisome proliferator-activated receptor gene expression in human tissues. Effects of obesity, weight loss, and regulation by insulin and glucocorticoids.
1997
Newly Synthesized Phosphatidylinositol Phosphates Are Required for Synaptic Norepinephrine but Not Glutamate or γ-Aminobutyric Acid (GABA) Release
1998 StandoutNobel
Peroxisome Proliferator-Activated Receptor Gamma Agonist Ligands Stimulate a Th2 Cytokine Response and Prevent Acute Colitis
2002
Rosiglitazone Monotherapy Is Effective in Patients with Type 2 Diabetes
2001
Peroxisome proliferator-activated receptor γ in diabetes and metabolism
2004
Control of Human Muscle-type Carnitine Palmitoyltransferase I Gene Transcription by Peroxisome Proliferator-activated Receptor
1998
Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas
2004 StandoutNobel
Mechanisms Controlling Mitochondrial Biogenesis and Respiration through the Thermogenic Coactivator PGC-1
1999 Standout
Adipocytes as regulators of energy balance and glucose homeostasis
2006 StandoutNature
Identification, Characterization, and Tissue Distribution of Human Peroxisome Proliferator-activated Receptor (PPAR) Isoforms PPARγ2 versus PPARγ1 and Activation with Retinoid X Receptor Agonists and Antagonists
1997
Minireview: Lipid Metabolism, Metabolic Diseases, and Peroxisome Proliferator-Activated Receptors
2003
Voltage-sensitive ion channels
1989
Pro12Ala Missense Mutation of the Peroxisome Proliferator Activated Receptor γ and Diabetes Mellitus
1999
Differential inhibition of macrophage foam-cell formation and atherosclerosis in mice by PPARα, β/δ, and γ
2004
A Bivalent Tarantula Toxin Activates the Capsaicin Receptor, TRPV1, by Targeting the Outer Pore Domain
2010 StandoutNobel
Regulation of skeletal muscle mass in mice by a new TGF-p superfamily member
1997 StandoutNature
Effect of Rosiglitazone on the Risk of Myocardial Infarction and Death from Cardiovascular Causes
2007 Standout
PPARgamma agonists in the treatment of type II diabetes: is increased fatness commensurate with long-term efficacy?
2003
Osf2/Cbfa1: A Transcriptional Activator of Osteoblast Differentiation
1997 Standout
Human nutrition, the gut microbiome and the immune system
2011 StandoutNature
Peroxisome proliferator‐activated receptor‐γ agonists prevent experimental autoimmune encephalomyelitis
2002
Macrophage-specific PPARγ controls alternative activation and improves insulin resistance
2007 StandoutNature
Intestinal‐specific PPARγ deficiency enhances tumorigenesis in ApcMin/+ mice
2006
Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-γ
1998 StandoutNature
Pioglitazone time-dependently reduces tumour necrosis factor-α level in muscle and improves metabolic abnormalities in Wistar fatty rats
1998
Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist
2012 StandoutNatureNobel
Differential Response of Estrogen Receptor α and Estrogen Receptor β to Partial Estrogen Agonists/Antagonists
1998
Troglitazone increases the number of small adipocytes without the change of white adipose tissue mass in obese Zucker rats.
1998
Muscarinic Receptor Subtypes
1990
Diet–microbiota interactions as moderators of human metabolism
2016 StandoutNature
Relationships of PPARγ and PPARγ2 mRNA levels to obesity, diabetes and hyperinsulinaemia in rhesus monkeys
1998
Differential Expression of Peroxisome Proliferator-Activated Receptor Subtypes During the Differentiation of Human Keratinocytes
1998
Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes
2005 StandoutNature
Chromosomal Localization and Partial Genomic Structure of the Human Peroxisome Proliferator Activated Receptor-Gamma (hPPARγ) Gene
1997
A Unique PPARγ Ligand with Potent Insulin-Sensitizing yet Weak Adipogenic Activity
2001
The Nuclear Receptors Peroxisome Proliferator-activated Receptor α and Rev-erbα Mediate the Species-specific Regulation of Apolipoprotein A-I Expression by Fibrates
1998
Fatty Acids, Eicosanoids, and Hypolipidemic Agents Identified as Ligands of Peroxisome Proliferator-Activated Receptors by Coactivator-Dependent Receptor Ligand Assay
1997
Adiponectin: a relevant player in PPARγ-agonist-mediated improvements in hepatic insulin sensitivity?
2005
Mechanisms linking obesity to insulin resistance and type 2 diabetes
2006 StandoutNature
Regulation of ATP-binding Cassette Sterol Transporters ABCG5 and ABCG8 by the Liver X Receptors α and β
2002
In VivoEffects of Pioglitazone on Uncoupling Protein-2 and -3 mRNA Levels in Skeletal Muscle of Hyperglycemic KK Mice
1998
Adipogenesis and Obesity: Rounding Out the Big Picture
1996
Mice Lacking Adiponectin Show Decreased Hepatic Insulin Sensitivity and Reduced Responsiveness to Peroxisome Proliferator-activated Receptor γ Agonists
2005
Combinatorial roles of nuclear receptors in inflammation and immunity
2005
Peroxisome Proliferator-activated Receptor-γ Ligands Inhibit Adipocyte 11β-Hydroxysteroid Dehydrogenase Type 1 Expression and Activity
2001
Peroxisome proliferator-activated receptor agonists
1997
Inositol trisphosphate and calcium signalling
1993 StandoutNature
Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-γ
2004 StandoutNature
The hormone resistin links obesity to diabetes
2001 StandoutNature
The biology of leptin: a review.
1998
Improved insulin-sensitivity in mice heterozygous for PPAR-γ deficiency
2000
Phase-dependent contributions from Ca2+ entry and Ca2+ release to caffeine-induced [Ca2+]i oscillations in bullfrog sympathetic neurons
1992
Interdomain communication regulating ligand binding by PPAR-γ
1998 Nature
Structure and dynamics of the M3 muscarinic acetylcholine receptor
2012 StandoutNatureNobel
Leptin and the regulation of body weight in mammals
1998 StandoutNature
Voltage-gated sodium channels as primary targets of diverse lipid-soluble neurotoxins
2002
Liver Peroxisome Proliferator-activated Receptor γ Contributes to Hepatic Steatosis, Triglyceride Clearance, and Regulation of Body Fat Mass
2003
Effect of the Pro12Ala Variant of the Human Peroxisome Proliferator-Activated Receptor γ2 Gene on Adiposity, Fat Distribution, and Insulin Sensitivity in Japanese Men
1998
A new class of synthetic retinoid antibiotics effective against bacterial persisters
2018 Nature
Estrogen-induced Production of a Peroxisome Proliferator-activated Receptor (PPAR) Ligand in a PPARγ-expressing Tissue
1998
Roles of PPARs in health and disease
2000 StandoutNature
War and peace at mucosal surfaces
2004
Differential inhibition of macrophage foam-cell formation and atherosclerosis in mice by PPARα, β/δ, and γ
2004
Identification of macrophage liver X receptors as inhibitors of atherosclerosis
2002
The Peroxisome Proliferator-Activated Receptor N-Terminal Domain Controls Isotype-Selective Gene Expression and Adipogenesis
2006
The Bile Acid Receptor FXR Is a Modulator of Intestinal Innate Immunity
2009
Intestinal antiinflammatory effect of 5-aminosalicylic acid is dependent on peroxisome proliferator–activated receptor-γ
2005
Expression and Function of PPARγ in Rat and Human Vascular Smooth Muscle Cells
2000
Structure of the STRA6 receptor for retinol uptake
2016 StandoutScienceNobel
Orphan Nuclear Receptors: From Gene to Function*
1999
Nuclear Receptors and Lipid Physiology: Opening the X-Files
2001 StandoutScience
The Enzymes, Regulation, and Genetics of Bile Acid Synthesis
2003 Standout
Primary Structure And Functional Expression of the 5HT 3 Receptor, A Serotonin-gated Ion Channel
1991 StandoutScienceNobel
Peroxisome Proliferator-Activated Receptor-γ-Deficient Heterozygous Mice Develop an Exacerbated Neural Antigen-Induced Th1 Response and Experimental Allergic Encephalomyelitis
2003
Insulin acutely regulates the expression of the peroxisome proliferator-activated receptor-gamma in human adipocytes.
1999
Fat and Beyond: The Diverse Biology of PPARγ
2008 Standout
Conditional Disruption of the Peroxisome Proliferator-Activated Receptor γ Gene in Mice Results in Lowered Expression of ABCA1, ABCG1, and apoE in Macrophages and Reduced Cholesterol Efflux
2002
Isolation of the cDNA for erythrocyte integral membrane protein of 28 kilodaltons: member of an ancient channel family.
1991 StandoutNobel
Heterozygous α 2A -adrenergic receptor mice unveil unique therapeutic benefits of partial agonists
2002 StandoutNobel
A Transgenic Model of Visceral Obesity and the Metabolic Syndrome
2001 StandoutScience
The mercury-sensitive residue at cysteine 189 in the CHIP28 water channel.
1993 StandoutNobel
ADIPOCYTE DIFFERENTIATION AND LEPTIN EXPRESSION
1997
Understanding Adipocyte Differentiation
1998 Standout
A caffeine‐ and ryanodine‐sensitive Ca2+ store in bullfrog sympathetic neurones modulates effects of Ca2+ entry on [Ca2+]i.
1992
Fluorine in Pharmaceuticals: Looking Beyond Intuition
2007 StandoutScience
Alternative splicing generates functionally distinct N-methyl-D-aspartate receptors.
1992 StandoutNobel
Pro12Ala substitution in the peroxisome proliferator-activated receptor-gamma2 is not associated with type 2 diabetes.
1999
Multiple Ca2+ channel types coexist to regulate synaptosomal neurotransmitter release.
1993
Single Subunits of the GABA A Receptor Form Ion Channels with Properties of the Native Receptor
1988 Science
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
Fluorine in medicinal chemistry: Recent therapeutic applications of fluorinated small molecules
2006 Standout
Association of the Pro12Ala variant in the peroxisome proliferator-activated receptor-gamma2 gene with obesity in two Caucasian populations.
1998
The PPARs: From Orphan Receptors to Drug Discovery
2000 Standout
Ionic permeation and blockade in Ca2+-activated K+ channels of bovine chromaffin cells.
1984
Bile Acids: Natural Ligands for an Orphan Nuclear Receptor
1999 StandoutScience
Nitrolinoleic acid: An endogenous peroxisome proliferator-activated receptor γ ligand
2005
Charybdotoxin, a protein inhibitor of single Ca2+-activated K+ channels from mammalian skeletal muscle
1985 StandoutNature
Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors α and δ
1997 Standout
Identification of simple arylfluorosulfates as potent agents against resistant bacteria
2021 StandoutNobel
PPARγ and PPARδ negatively regulate specific subsets of lipopolysaccharide and IFN-γ target genes in macrophages
2003
Regulation of Peroxisome Proliferator-Activated Receptor γ Expression by Adipocyte Differentiation and Determination Factor 1/Sterol Regulatory Element Binding Protein 1: Implications for Adipocyte Differentiation and Metabolism
1999
Activation of acetylcholine receptor channels by covalently bound agonists in cultured rat myoballs.
1986
Neuroscience: Breaking Down Scientific Barriers to the Study of Brain and Mind
2000 StandoutScienceNobel
Host-Gut Microbiota Metabolic Interactions
2012 StandoutScience
Troglitazone Effects on Gene Expression in Human Skeletal Muscle of Type II Diabetes Involve Up-Regulation of Peroxisome Proliferator-Activated Receptor-γ1
1998
Enhanced sensitivity to DSS colitis caused by a hypomorphic Mbtps1 mutation disrupting the ATF6-driven unfolded protein response
2009 StandoutNobel
Peroxisome Proliferator-Activated Receptors: Nuclear Control of Metabolism*
1999 Standout
NUCLEAR RECEPTORS IN MACROPHAGE BIOLOGY: At the Crossroads of Lipid Metabolism and Inflammation
2004
Activation of Peroxisome Proliferator-Activated Receptor γ Does Not Inhibit IL-6 or TNF-α Responses of Macrophages to Lipopolysaccharide In Vitro or In Vivo
2000
Role of Skeletal Muscle in Thiazolidinedione Insulin Sensitizer (PPARγ Agonist) Action
1998
Peroxisome Proliferator-Activated Receptors γ and α Mediate in Vivo Regulation of Uncoupling Protein (UCP-1, UCP-2, UCP-3) Gene Expression
1998
Metabolic Effects of Troglitazone Monotherapy in Type 2 Diabetes Mellitus
1998
RXR Agonists Activate PPARα-Inducible Genes, Lower Triglycerides, and Raise HDL Levels In Vivo
1998
Identification of a Nuclear Receptor for Bile Acids
1999 StandoutScience
Role of Peroxisome Proliferator-Activated Receptor-γ in Maintenance of the Characteristics of Mature 3T3-L1 Adipocytes
2002
Nuclear Receptors Have Distinct Affinities for Coactivators: Characterization by Fluorescence Resonance Energy Transfer
1998
The Connectivity Map: Using Gene-Expression Signatures to Connect Small Molecules, Genes, and Disease
2006 StandoutScience
Estrogen inhibits the vascular injury response in estrogen receptor β-deficient female mice
1999 StandoutNobel
Currents through single glutamate receptor channels in outside‐out patches from rat cerebellar granule cells.
1991
Works of Mark D. Leibowitz being referenced
High affinity block of myocardial L-type calcium channels by the spider toxin omega-Aga-toxin IIIA: advantages over 1,4-dihydropyridines.
1992
Agonists that suppress M-current elicit phosphoinositide turnover and Ca2+ transients, but these events do not explain M-current suppression
1988
RAR and RXR modulation in cancer and metabolic disease
2007
Thiazolidinediones produce a conformational change in peroxisomal proliferator-activated receptor-gamma: binding and activation correlate with antidiabetic actions in db/db mice.
1996
Down-regulation of the Expression of the Obese Gene by an Antidiabetic Thiazolidinedione in Zucker Diabetic Fatty Rats and db/db Mice
1996
A PPARγ mutant serves as a dominant negative inhibitor of PPAR signaling and is localized in the nucleus
2000
A high-conductance anion channel in adult amphibian skeletal muscle
1987
Effects of Rexinoids on Glucose Transport and Insulin-mediated Signaling in Skeletal Muscles of Diabetic (db/db) Mice
2004
Molecular Cloning, Expression and Characterization of Human Peroxisome Proliferator Activated Receptors γ1 and γ2
1996
Differential Effects of Rexinoids and Thiazolidinediones on Metabolic Gene Expression in Diabetic Rodents
2001
Design and synthesis of fluorinated RXR modulators
2003
Activation of PPARδ alters lipid metabolism in db/db mice
2000
Acetylcholine receptor kinetics. A description from single-channel currents at snake neuromuscular junctions
1982
Attenuation of Colon Inflammation through Activators of the Retinoid X Receptor (Rxr)/Peroxisome Proliferator–Activated Receptor γ (Pparγ) Heterodimer
2001
Single-channel acetylcholine receptor kinetics
1984
Reduction of atherosclerosis in apolipoprotein E knockout mice by activation of the retinoid X receptor
2001
Voltage-dependent gating of veratridine-modified Na channels.
1986