Standout Papers
Citation Impact
Citing Papers
Structures of the CXCR4 Chemokine GPCR with Small-Molecule and Cyclic Peptide Antagonists
2010 StandoutScience
Plasmacytoid dendritic cells initiate a complex chemokine and cytokine network and are a viable drug target in chronic HCV patients
2007 StandoutNobel
Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases
2007 Standout
Distinct fibroblast lineages determine dermal architecture in skin development and repair
2013 StandoutNature
Genome-wide features of neuroendocrine regulation in Drosophila by the basic helix-loop-helix transcription factor DIMMED
2015 StandoutNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
β-Arrestin-dependent Constitutive Internalization of the Human Chemokine Decoy Receptor D6
2004 StandoutNobel
Role for Hedgehog signaling in hepatic stellate cell activation and viability
2005
Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality
2009 StandoutNobel
Regulation of hepatic stellate cell proliferation and collagen synthesis by proteinase-activated receptors
2002
Cancer Invasion and the Microenvironment: Plasticity and Reciprocity
2011 Standout
X4 and R5 HIV-1 Have Distinct Post-entry Requirements for Uracil DNA Glycosylase during Infection of Primary Cells
2010 StandoutNobel
Contact Guidance Mediated Three-Dimensional Cell Migration is Regulated by Rho/ROCK-Dependent Matrix Reorganization
2008
Early Hepatic Stellate Cell Activation Predicts Severe Hepatitis C Recurrence after Liver Transplantation
2005
Association of differentially expressed genes with activation of mouse hepatic stellate cells by high-density cDNA mircoarray
2004
Matrix Metalloproteinase Processing of CXCL11/I-TAC Results in Loss of Chemoattractant Activity and Altered Glycosaminoglycan Binding
2008
Second-harmonic imaging microscopy for visualizing biomolecular arrays in cells, tissues and organisms
2003
Mechanisms of liver fibrosis
2005
Liver Gene Expression Signature of Mild Fibrosis in Patients With Chronic Hepatitis C
2005
Interferon type I gene expression in chronic hepatitis C
2004
Identification of endoribonuclease specific cleavage positions reveals novel targets of RNase III inStreptococcus pyogenes
2017 StandoutNobel
Sensing extracellular matrix: An update on discoidin domain receptor function
2006
The Pseudomonas aeruginosa Transcriptome in Planktonic Cultures and Static Biofilms Using RNA Sequencing
2012
Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome
2013 StandoutNature
Pro-resolving lipid mediators are leads for resolution physiology
2014 StandoutNature
Cancer Metastasis: Building a Framework
2006 Standout
Molecular viral oncology of hepatocellular carcinoma
2003
Lymphangiogenesis: Molecular Mechanisms and Future Promise
2010 Standout
The biology and function of fibroblasts in cancer
2016 Standout
Aberrant Wnt/β-Catenin Pathway Activation in Idiopathic Pulmonary Fibrosis
2003
Triazolopiperazine-amides as dipeptidyl peptidase IV inhibitors: Close analogs of JANUVIA™ (sitagliptin phosphate)
2007
Gene Expression Patterns That Correlate With Hepatitis C and Early Progression to Fibrosis in Liver Transplant Recipients
2006
Hepatocellular carcinoma
2021 Standout
Bat-to-human: spike features determining ‘host jump’ of coronaviruses SARS-CoV, MERS-CoV, and beyond
2015
Mutations in Distant Residues Moderately Increase the Enantioselectivity of Pseudomonas fluorescens Esterase towards Methyl 3Bromo‐2‐methylpropanoate and Ethyl 3Phenylbutyrate
2003
Cell-surface enzymes in control of leukocyte trafficking
2005
The bone marrow niche for haematopoietic stem cells
2014 StandoutNature
Cardiovascular effects of gliptins
2013
Role of the Microbiota in Immunity and Inflammation
2014 Standout
Bat Origins of MERS-CoV Supported by Bat Coronavirus HKU4 Usage of Human Receptor CD26
2014
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
Dimerization of chemokine receptors in living cells: key to receptor function and novel targets for therapy
2008
Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
2007 StandoutNature
Novel tetrahydropyran analogs as dipeptidyl peptidase IV inhibitors: Profile of clinical candidate (2R,3S,5R)-2-(2,5-difluorophenyl)-5-[2-(methylsulfonyl)-2,6-dihydropyrrolo[3,4-c]pyrazol-5(4H)-yl]tetrahydro-2H-pyran-3-amine (23)
2013
Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26
2013 Nature
Biased clustered substitutions in the human genome: The footprints of male-driven biased gene conversion
2007
Exploiting dendritic cells to improve vaccine efficacy
2002 StandoutNobel
Matrix Metalloproteinases: Regulators of the Tumor Microenvironment
2010 Standout
Human hepatic stellate cell lines, LX-1 and LX-2: new tools for analysis of hepatic fibrosis
2004
Differential expression genes analyzed by cDNA array in the regulation of rat hepatic fibrogenesis
2006
Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein
2020 Standout
Fusion of monocytes and macrophages with HIV-1 correlates with biochemical properties of CXCR4 and CCR5
1999
Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC
2013 StandoutNature
ESkine, a Novel β-Chemokine, Is Differentially Spliced to Produce Secretable and Nuclear Targeted Isoforms
1999
Fibroblast activation protein‐α, a stromal cell surface protease, shapes key features of cancer associated fibroblasts through proteome and degradome alterations
2015
GFAP promoter directs lacZ expression specifically in a rat hepatic stellate cell line
2006
Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection
1995 StandoutNature
Structural and Functional Basis of SARS-CoV-2 Entry by Using Human ACE2
2020 Standout
Collagen reorganization at the tumor-stromal interface facilitates local invasion
2006
Zonal hierarchy of differentiation markers and nestin expression during oval cell mediated rat liver regeneration
2006
TP53 and liver carcinogenesis
2003
Alcoholic Liver Disease: Pathogenesis and New Therapeutic Targets
2011 Standout
Does Mycobacterium avium subspecies paratuberculosis cause Crohn’s disease?: Table 1
2005
Selective Blockade of the Capsaicin Receptor TRPV1 Attenuates Bone Cancer Pain
2005 StandoutNobel
NF-κB functions as a tumour promoter in inflammation-associated cancer
2004 StandoutNature
Fibroblasts in cancer
2006 Standout
The multifunctional or moonlighting protein CD26/DPPIV
2003
Evolution and Functions of Long Noncoding RNAs
2009 Standout
Modulation of chemokine receptor activity through dimerization and crosstalk
2008
Saxagliptin and Cardiovascular Outcomes in Patients with Type 2 Diabetes Mellitus
2013 Standout
Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling
2009 Standout
Adenosine stimulation of the proliferation of colorectal carcinoma cell lines
2003
Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver
2008 Standout
LD78β, A Non-allelic Variant of Human MIP-1α (LD78α), Has Enhanced Receptor Interactions and Potent HIV Suppressive Activity
1999
Hepatic stellate cells and fibrosis progression in patients with nonalcoholic fatty liver disease
2005
Dipeptidyl-Peptidase IV from Bench to Bedside: An Update on Structural Properties, Functions, and Clinical Aspects of the Enzyme DPP IV
2003
Neuroregulation of the neuroendocrine compartment of the liver
2004
The Many Roles of Chemokines and Chemokine Receptors in Inflammation
2006 Standout
Engineering the third wave of biocatalysis
2012 StandoutNature
Mechanism-Based Profiling of Enzyme Families
2006
Fluorine in medicinal chemistry
2007 Standout
How Does HIV Cause AIDS?
1993 Science
Upconversion Nanoparticles: Design, Nanochemistry, and Applications in Theranostics
2014 Standout
The efficiency of acute infection of CD4+ T cells is markedly enhanced in the setting of antigen-specific immune activation.
1996 StandoutNobel
Quantification of CD4, CCR5, and CXCR4 levels on lymphocyte subsets, dendritic cells, and differentially conditioned monocyte-derived macrophages
1999 StandoutNobel
Efficient Differentiation of Functional Hepatocytes from Human Embryonic Stem Cells
2008
Immune activation and viral burden in acute disease induced by simian immunodeficiency virus SIVsmmPBj14: correlation between in vitro and in vivo events
1994
Linear mRNA Amplification from as Little as 5 ng Total RNA for Global gene Expression Analysis
2004
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
International Union of Pharmacology. XXII. Nomenclature for Chemokine Receptors
2000 Standout
dUTPase-minus caprine arthritis-encephalitis virus is attenuated for pathogenesis and accumulates G-to-A substitutions
1997
Dendritic cell dynamics in the liver and hepatic lymph
2000
Dipeptidyl Peptidase IV and Its Inhibitors: Therapeutics for Type 2 Diabetes and What Else?
2013
Increased Wnt Signaling During Aging Alters Muscle Stem Cell Fate and Increases Fibrosis
2007 StandoutScience
Regulation of apoptosis by the circadian clock through NF-κB signaling
2011 StandoutNobel
Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells
2012 StandoutNobel
Cytokine Regulation of Human Immunodeficiency Virus Type 1 Entry and Replication in Human Monocytes/Macrophages through Modulation of CCR5 Expression
1998
Anti-HIV-1 and chemotactic activities of human stromal cell-derived factor 1α (SDF-1α) and SDF-1β are abolished by CD26/dipeptidyl peptidase IV-mediated cleavage
1998 StandoutNobel
Chemokine immunobiology in HIV-1 pathogenesis
1999
Depletion of stromal cells expressing fibroblast activation protein-α from skeletal muscle and bone marrow results in cachexia and anemia
2013
Fibroblast heterogeneity in the cancer wound
2014
T cell exclusion, immune privilege, and the tumor microenvironment
2015 StandoutScience
New Drugs for the Treatment of Diabetes
2008
Apoptotic neutrophils and T cells sequester chemokines during immune response resolution through modulation of CCR5 expression
2006
Arylfluorosulfates Inactivate Intracellular Lipid Binding Protein(s) through Chemoselective SuFEx Reaction with a Binding Site Tyr Residue
2016 StandoutNobel
Cu-Catalyzed Azide−Alkyne Cycloaddition
2008 StandoutNobel
Microbial Translocation Across the GI Tract
2012
Works of Mark D. Gorrell being referenced
Expression of the rat CD26 Antigen (dipeptidyl peptidase IV) on subpopulations of rat lymphocytes
1991
Tumour necrosis factor and interleukin 6 production during interaction between activated CD4+ lymphocytes and simian immunodeficiency virus-infected macrophages
1992
CD26: A Multifunctional Integral Membrane and Secreted Protein of Activated Lymphocytes
2001
Intrahepatic expression of the hepatic stellate cell marker fibroblast activation protein correlates with the degree of fibrosis in hepatitis C virus infection
2002
Inflammation and Repair in Viral Hepatitis C
2007
Relating Structure to Function in the Beta-Propeller Domain of Dipeptidyl Peptidase IV
2006
Gene expression characteristics of a cystic fibrosis epidemic strain ofPseudomonas aeruginosaduring biofilm and planktonic growth
2009
Insights into the Pathobiology of Hepatitis C Virus-Associated Cirrhosis
2002
Identification of the Bile Canalicular Cell Surface Molecule Gp110 As the Ectopeptidase Dipeptidyl Peptidase Iv: An Analysis by Tissue Distribution, Purification And N –Terminal Amino Acid Sequence
1990
Stromal cell‐derived factors 1α and 1β, inflammatory protein‐10 and interferon‐inducible T cell chemo‐attractant are novel substrates of dipeptidyl peptidase 8
2008
Hepatocellular carcinoma: Mouse models and the potential roles of proteases
2016
Post Proline Cleaving Peptidases Having DP IV Like Enzyme Activity
2006
SMART amplification maintains representation of relative gene expression: quantitative validation by real time PCR and application to studies of alcoholic liver disease in primates
2003
Cloning, expression and chromosomal localization of a novel human dipeptidyl peptidase (DPP) IV homolog, DPP8
2000
Neuropeptide Y, B‐type natriuretic peptide, substance P and peptide YY are novel substrates of fibroblast activation protein‐α
2011
Fibroblast Activation Protein: A Cell Surface Dipeptidyl Peptidase and Gelatinase Expressed by Stellate Cells At the Tissue Remodelling Interface in Human Cirrhosis
1999
Binding to human dipeptidyl peptidase IV by adenosine deaminase and antibodies that inhibit ligand binding involves overlapping, discontinuous sites on a predicted β propeller domain
1999
Fibroblast Activation Protein Increases Apoptosis, Cell Adhesion, and Migration by the LX-2 Human Stellate Cell Line *
2005
3-Dimensional imaging of collagen using second harmonic generation
2003
Intrahepatic gene expression in human alcoholic hepatitis
2006
Two highly conserved glutamic acid residues in the predicted β propeller domain of dipeptidyl peptidase IV are required for its enzyme activity
1999
Molecular pathogenesis of liver disease: an approach to hepatic inflammation, cirrhosis and liver transplant tolerance
2000
Cysticercosis: cellular immune responses during primary and secondary infection
1990
Novel Differential Gene Expression in Human Cirrhosis Detected by Suppression Subtractive Hybridization
2003
Dipeptidyl Peptidase IV Gene Family
2005
Ovine lentivirus is macrophagetropic and does not replicate productively in T lymphocytes
1992
Understanding fibroblast activation protein (FAP): Substrates, activities, expression and targeting for cancer therapy
2014
Gene array analysis and the liver
2002
Dipeptidyl peptidase IV and related enzymes in cell biology and liver disorders
2005
Inhibitor selectivity in the clinical application of dipeptidyl peptidase-4 inhibition
2009
Structural Requirements for Catalysis, Expression, and Dimerization in the CD26/DPIV Gene Family
2002
Regulation of the Receptor Specificity and Function of the Chemokine RANTES (Regulated on Activation, Normal T Cell Expressed and Secreted) by Dipeptidyl Peptidase IV (CD26)-mediated Cleavage
1997
Transcriptome analyses and biofilm-forming characteristics of a clonal Pseudomonas aeruginosa from the cystic fibrosis lung
2008