Citation Impact
Citing Papers
Alterations in 5-HT 1B Receptor Function by p11 in Depression-Like States
2006 Science
Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels
2010 StandoutScienceNobel
Evolution of new nonantibody proteins via iterative somatic hypermutation
2004 StandoutNobel
The Cell and Molecular Basis of Mechanical, Cold, and Inflammatory Pain
2008 Science
Development of a Functional Assay for Homologous Recombination Status in Primary Cultures of Epithelial Ovarian Tumor and Correlation with Sensitivity to Poly(ADP-Ribose) Polymerase Inhibitors
2010
Cytoplasmic ankyrin repeats of transient receptor potential A1 (TRPA1) dictate sensitivity to thermal and chemical stimuli
2011 StandoutNobel
PARP inhibitors: Synthetic lethality in the clinic
2017 StandoutScience
The UK Biobank resource with deep phenotyping and genomic data
2018 StandoutNature
A Gain-of-Function Mutation in TRPA1 Causes Familial Episodic Pain Syndrome
2010
Epidermal Merkel cells are mechanosensory cells that tune mammalian touch receptors
2014 StandoutNatureNobel
Pain Genes
2008
Structure of the TRPA1 ion channel suggests regulatory mechanisms
2015 StandoutNatureNobel
RIM Proteins Tether Ca2+ Channels to Presynaptic Active Zones via a Direct PDZ-Domain Interaction
2011 StandoutNobel
Discoveries in structure and physiology of mechanically activated ion channels
2020 StandoutNatureNobel
Introduction of a subtle mutation into the Hox-2.6 locus in embryonic stem cells
1991 Nature
Voltage-Gated Sodium Channels: Mutations, Channelopathies and Targets
2011
Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines
2007 StandoutNatureNobel
AID and mismatch repair in antibody diversification
2002
Molecular mechanisms of nociception
2001 StandoutNatureNobel
Isolation, characterization and total regioselective synthesis of the novel μO-conotoxin MfVIA from Conus magnificus that targets voltage-gated sodium channels
2012
Gain-of-Function Mutations in SCN11A Cause Familial Episodic Pain
2013
Genetic stability of gene targeted immunoglobulin loci. I. Heavy chain isotype exchange induced by a universal gene replacement vector
1996
Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain
2016 StandoutNatureNobel
Phenotyping sensory nerve endings in vitro in the mouse
2009
Differential Block of Sensory Neuronal Voltage-Gated Sodium Channels by Lacosamide [(2 R)-2-(Acetylamino)-N-benzyl-3-methoxypropanamide], Lidocaine, and Carbamazepine
2008
Calmodulin Regulates Current Density and Frequency-Dependent Inhibition of Sodium Channel Nav1.8 in DRG Neurons
2006
Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide
1999 StandoutNatureNobel
Piezo proteins are pore-forming subunits of mechanically activated channels
2012 StandoutNatureNobel
The NaV1.7 sodium channel: from molecule to man
2012
Mechanosensitive currents in the neurites of cultured mouse sensory neurones
2006
A Bivalent Tarantula Toxin Activates the Capsaicin Receptor, TRPV1, by Targeting the Outer Pore Domain
2010 StandoutNobel
Molecular basis of ancestral vertebrate electroreception
2017 StandoutNatureNobel
Nav1.7 Mutant A863P in Erythromelalgia: Effects of Altered Activation and Steady-State Inactivation on Excitability of Nociceptive Dorsal Root Ganglion Neurons
2006
An SCN9A channelopathy causes congenital inability to experience pain
2006 StandoutNature
A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain
2011 StandoutNatureNobel
Involvement of Na+ channels in pain pathways
2001
Protein folding in the cell
1992 StandoutNature
Piezo2 is the major transducer of mechanical forces for touch sensation in mice
2014 StandoutNatureNobel
Physiology and Pathophysiology of Sodium Channel Inactivation
2016
A Cell-Penetrating Scorpion Toxin Enables Mode-Specific Modulation of TRPA1 and Pain
2019 StandoutNobel
Sensory neuron sodium channel Nav1.8 is essential for pain at low temperatures
2007 Nature
TRPV1 structures in distinct conformations reveal activation mechanisms
2013 StandoutNatureNobel
Enterochromaffin Cells Are Gut Chemosensors that Couple to Sensory Neural Pathways
2017 StandoutNobel
Molecular basis of infrared detection by snakes
2010 StandoutNatureNobel
NaV1.7 Gain-of-Function Mutations as a Continuum: A1632E Displays Physiological Changes Associated with Erythromelalgia and Paroxysmal Extreme Pain Disorder Mutations and Produces Symptoms of Both Disorders
2008
Naturally occurring antibodies devoid of light chains
1993 StandoutNature
The TTX‐Resistant Sodium Channel Nav1.8 (SNS/PN3): Expression and Correlation with Membrane Properties in Rat Nociceptive Primary Afferent Neurons
2003
Painful peripheral neuropathy and sodium channel mutations
2014
Chapter 4 Genetics and Molecular Pathophysiology of Nav1.7‐Related Pain Syndromes
2008
TREK‐1, a K+ channel involved in polymodal pain perception
2006
A ‘toothache tree’ alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain
2013
DNA hypomethylation leads to elevated mutation rates
1998 Nature
Cellular and Molecular Mechanisms of Pain
2009 StandoutNobel
State- and Use-Dependent Block of Muscle Nav1.4 and Neuronal Nav1.7 Voltage-Gated Na+ Channel Isoforms by Ranolazine
2007
Evidence for the involvement of ASIC3 in sensory mechanotransduction in proprioceptors
2016
Multiple sodium channels and their roles in electrogenesis within dorsal root ganglion neurons
2006
Comparative study of the distribution of the α‐subunits of voltage‐gated sodium channels in normal and axotomized rat dorsal root ganglion neurons
2008
Intracellular Signaling in Primary Sensory Neurons and Persistent Pain
2008
Deconstructing voltage sensor function and pharmacology in sodium channels
2008 Nature
Molecular Basis for Species-Specific Sensitivity to “Hot” Chili Peppers
2002 StandoutNobel
De novo expression of Nav1.7 in injured putative proprioceptive afferents: Multiple tetrodotoxin-sensitive sodium channels are retained in the rat dorsal root after spinal nerve ligation
2014
Mechanisms of precise genome editing using oligonucleotide donors
2017
Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1
2004 StandoutNatureNobel
Sporadic onset of erythermalgia: A gain‐of‐function mutation in Nav1.7
2006
International Union of Pharmacology. XLVII. Nomenclature and Structure-Function Relationships of Voltage-Gated Sodium Channels
2005 Standout
Nociceptors—Noxious Stimulus Detectors
2007
Patterns of activity-dependent conduction velocity changes differentiate classes of unmyelinated mechano-insensitive afferents including cold nociceptors, in pig and in human
2009
The molecular neurobiology of depression
2008 StandoutNature
Validating therapeutic targets through human genetics
2013
Nociceptors: the sensors of the pain pathway
2010 StandoutNobel
Parallel “Pain” Pathways Arise from Subpopulations of Primary Afferent Nociceptor
2005
Repair of Double-Strand Breaks by Homologous Recombination in Mismatch Repair-Defective Mammalian Cells
2001
Accumulation of the FACT complex, as well as histone H3.3, serves as a target marker for somatic hypermutation
2013 StandoutNobel
Functional properties and toxin pharmacology of a dorsal root ganglion sodium channel viewed through its voltage sensors
2011
Cotransformation and Gene Targeting in Mouse Embryonic Stem Cells
1991 StandoutNobel
Slow Closed-State Inactivation: A Novel Mechanism Underlying Ramp Currents in Cells Expressing the hNE/PN1 Sodium Channel
1998
Proliferation of multipotent hematopoietic cells controlled by a truncated erythropoietin receptor transgene.
1996 StandoutNobel
Progress in Genetic Studies of Pain and Analgesia
2008
Sodium Channels in Normal and Pathological Pain
2010
Epigenetic Reprogramming in Mammalian Development
2001 StandoutScience
Loss of the maternal H19 gene induces changes in Igf 2 methylation in both cis and trans
1997
Assembly and secretion of heavy chains that do not associate posttranslationally with immunoglobulin heavy chain-binding protein.
1987 Nobel
Homologous Recombination in Hybridoma Cells: Dependence on Time and Fragment Length
1990
Neuropathic Pain Develops Normally in Mice Lacking both Nav1.7 and Nav1.8
2005
Impaired Nociception and Pain Sensation in Mice Lacking the Capsaicin Receptor
2000 StandoutScienceNobel
The hitchhiker’s guide to the voltage-gated sodium channel galaxy
2015
Vanilloid (Capsaicin) Receptors and Mechanisms
1999 Standout
Testing an "in-out" targeting procedure for making subtle genomic modifications in mouse embryonic stem cells.
1991 StandoutNobel
Pharmacological Dissection and Distribution of NaN/Nav1.9, T-type Ca2+ Currents, and Mechanically Activated Cation Currents in Different Populations of DRG Neurons
2006
Gene correction in hematopoietic progenitor cells by homologous recombination
2000 StandoutNobel
A dominant positive and negative selectable gene for use in mammalian cells.
1991 StandoutNobel
CHEMICAL ACTIVATORS OF SENSORY NEURONS
1997
The Role of Sodium Channels in Chronic Inflammatory and Neuropathic Pain
2006
Properties of Kv2.1 K+ channels expressed in transfected mammalian cells.
1994
Pharmacology of the Na v 1.1 domain IV voltage sensor reveals coupling between inactivation gating processes
2017 StandoutNobel
Correction of a human beta S-globin gene by gene targeting.
1991 StandoutNobel
HOMOLOGOUS RECOMBINATION IN MAMMALIAN CELLS
1989
Cotransformation and gene targeting in mouse embryonic stem cells.
1991 StandoutNobel
The Molecular Biology of Memory Storage: A Dialogue Between Genes and Synapses
2001 StandoutScienceNobel
High rate of CAD gene amplification in human cells deficient in MLH1 or MSH6
2001 StandoutNobel
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
Are Voltage-Gated Sodium Channels on the Dorsal Root Ganglion Involved in the Development of Neuropathic Pain?
2011
Temporal Control of Gene Deletion in Sensory Ganglia Using a Tamoxifen-InducibleAdvillin-CreERT2Recombinase Mouse
2011
Introduction of a lacZ reporter gene into the mouse int-2 locus by homologous recombination.
1990 StandoutNobel
Lys49 myotoxin from the Brazilian lancehead pit viper elicits pain through regulated ATP release
2017 StandoutNobel
Hypermorphic mutation of the voltage-gated sodium channel encoding gene Scn10a causes a dramatic stimulus-dependent neurobehavioral phenotype
2011 StandoutNobel
RNA-editing cytidine deaminase Apobec-1 is unable to induce somatic hypermutation in mammalian cells
2003 StandoutNobel
Works of Mark D. Baker being referenced
μO-conotoxin MrVIB selectively blocks Na v 1.8 sensory neuron specific sodium channels and chronic pain behavior without motor deficits
2006
Voltage‐gated sodium channels and pain pathways
2004
Small RNAs Control Sodium Channel Expression, Nociceptor Excitability, and Pain Thresholds
2010
Neurological perspectives on voltage-gated sodium channels
2012
Recovery of deficient homologous recombination in Brca2-depleted mouse cells by wild-type Rad51 expression
2008
SCN9A Mutations in Paroxysmal Extreme Pain Disorder: Allelic Variants Underlie Distinct Channel Defects and Phenotypes
2006
The action of capsaicin on type I delayed rectifier K + currents in rabbit Schwann cells
1994
Selective block of late Na+ current by local anaesthetics in rat large sensory neurones
2000
Immunoglobulin molecular genetics: the prospects for mutational analysis of the chromosomal immunoglobulin genes
1989
Annexin II light chain regulates sensory neuron-specific sodium channel expression
2002 Nature
On the block of outward potassium current in rabbit Schwann cells by internal sodium ions
1992
Sensory neuron proteins interact with the intracellular domains of sodium channel NaV1.8
2003
Mechanisms Involved in Targeted Gene Replacement in Mammalian Cells
2000
Restoration of a normal level of immunoglobulin production in a hybridoma cell line following modification of the chromosomal immunoglobulin μ gene by gene replacement
1994
Low-Threshold, Persistent Sodium Current in Rat Large Dorsal Root Ganglion Neurons in Culture
1997
Nociceptor-specific gene deletion reveals a major role for Nav1.7 (PN1) in acute and inflammatory pain
2004
Use of a Small Palindrome Genetic Marker to Investigate Mechanisms of Double-Strand-Break Repair in Mammalian Cells
2000
Homologous recombination can restore normal immunoglobulin production in a mutant hybridoma cell line.
1988
High-Frequency Homologous Recombination between Duplicate Chromosomal Immunoglobulin μ Heavy-Chain Constant Regions
1989
The Mechanism of Mammalian Gene Replacement Is Consistent with the Formation of Long Regions of Heteroduplex DNA Associated with Two Crossing-Over Events
2001
Analysis of hybridoma mutants defective in synthesis of immunoglobulin M
1986
Nociceptor-specific gene deletion using heterozygous NaV1.8-Cre recombinase mice
2004
Nerve Injury Induces Robust Allodynia and Ectopic Discharges in Nav1.3 Null Mutant Mice
2006
Homologous Recombination between Transferred and Chromosomal Immunoglobulin κ Genes
1988
Sodium Channels in Primary Sensory Neurons: Relationship to Pain States
2001
High-frequency homologous recombination between duplicate chromosomal immunoglobulin mu heavy-chain constant regions.
1989
Interchromosomal recombination is suppressed in mammalian somatic cells.
1995