Citation Impact
Citing Papers
A Transient and Low-Populated Protein-Folding Intermediate at Atomic Resolution
2010 Science
Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation
2014 StandoutScienceNobel
Loss of conformational entropy in protein folding calculated using realistic ensembles and its implications for NMR-based calculations
2014 StandoutNobel
β-Arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2
2009 StandoutNobel
Innovative scattering analysis shows that hydrophobic disordered proteins are expanded in water
2017 StandoutScienceNobel
Structure of DNMT1-DNA Complex Reveals a Role for Autoinhibition in Maintenance DNA Methylation
2010 Science
Global analysis of protein folding using massively parallel design, synthesis, and testing
2017 StandoutScienceNobel
Atomic-Level Characterization of the Structural Dynamics of Proteins
2010 StandoutScienceNobel
Origins of Specificity in Protein-DNA Recognition
2010
The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins
2019 StandoutNobel
Single Reconstituted Neuronal SNARE Complexes Zipper in Three Distinct Stages
2012 StandoutScienceNobel
Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1
2009 StandoutScience
Structure of the human TRPM4 ion channel in a lipid nanodisc
2017 StandoutScienceNobel
NMR Structure Determination for Larger Proteins Using Backbone-Only Data
2010 StandoutScienceNobel
Accurate computational design of multipass transmembrane proteins
2018 StandoutScienceNobel
Hierarchical design of pseudosymmetric protein nanocages
2024 StandoutNatureNobel
The Indispensable N-Terminal Half of eIF3j/HCR1 Cooperates with its Structurally Conserved Binding Partner eIF3b/PRT1-RRM and with eIF1A in Stringent AUG Selection
2010
DNA interrogation by the CRISPR RNA-guided endonuclease Cas9
2014 StandoutNatureNobel
Adaptive evolution of SCML1 in primates, a gene involved in male reproduction
2008
Engineered receptors for soluble cellular communication and disease sensing
2024 StandoutNatureNobel
Structure of a mammalian ryanodine receptor
2014 StandoutNatureNobel
Structural Basis for Gating and Activation of RyR1
2016 StandoutNobel
Molecular architecture and mechanism of an icosahedral pyruvate dehydrogenase complex: a multifunctional catalytic machine
2002
Crystal structure of the human COP9 signalosome
2014 Nature
The Highly Cooperative Folding of Small Naturally Occurring Proteins Is Likely the Result of Natural Selection
2007 StandoutNobel
Poly(ADP-ribosyl)ation by PARP-1: `PAR-laying' NAD+ into a nuclear signal
2005
Atomic model of the type III secretion system needle
2012 StandoutNatureNobel
Lysine‐63‐linked ubiquitination is required for endolysosomal degradation of class I molecules
2006
Understanding the language of Lys36 methylation at histone H3
2012
Innovation by homologous recombination
2013 StandoutNobel
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
Fractional 13C enrichment of isolated carbons using [1-13C]- or [2-13C]-glucose facilitates the accurate measurement of dynamics at backbone Cα and side-chain methyl positions in proteins
2007
Structural analysis of an eIF3 subcomplex reveals conserved interactions required for a stable and proper translation pre-initiation complex assembly
2011
Splicing regulates NAD metabolite binding to histone macroH2A
2005
Tension-tuned receptors for synthetic mechanotransduction and intercellular force detection
2023
Function and regulation of cullin–RING ubiquitin ligases
2005 Standout
Structural Organization of the 19S Proteasome Lid: Insights from MS of Intact Complexes
2006
Sub-microsecond Protein Folding
2006
Assessing the accuracy of physical models used in protein-folding simulations: quantitative evidence from long molecular dynamics simulations
2014
Role of the Biomolecular Energy Gap in Protein Design, Structure, and Evolution
2012 StandoutNobel
Inactivating Chromosomes
2003
Optimal Determination of Particle Orientation, Absolute Hand, and Contrast Loss in Single-particle Electron Cryomicroscopy
2003 StandoutNobel
Poly(ADP-ribosyl)ation regulates CTCF-dependent chromatin insulation
2004
B-aggressive Lymphoma Family Proteins Have Unique Domains That Modulate Transcription and Exhibit Poly(ADP-ribose) Polymerase Activity
2005
Direct Evidence for the Size and Conformational Variability of the Pyruvate Dehydrogenase Complex Revealed by Three-dimensional Electron Microscopy
2001
Intermediates: ubiquitous species on folding energy landscapes?
2007
Breaking the chains: structure and function of the deubiquitinases
2009 Standout
Fast protein folding kinetics
2014
The Folding Pathway of an FF domain: Characterization of an On-pathway Intermediate State Under Folding Conditions by 15N, 13Cα and 13C-methyl Relaxation Dispersion and 1H/2H-exchange NMR Spectroscopy
2007
Solution structure of a minor and transiently formed state of a T4 lysozyme mutant
2011 StandoutNatureNobel
Structure of mammalian eIF3 in the context of the 43S preinitiation complex
2015 StandoutNatureNobel
Engineering explored
2014 StandoutNatureNobel
Poly(ADP-ribose): novel functions for an old molecule
2006 Standout
Improved protein structure prediction using potentials from deep learning
2020 StandoutNatureNobel
Lessons in stability from thermophilic proteins
2006
De novo design of a fluorescence-activating β-barrel
2018 StandoutNatureNobel
De novo design of bioactive protein switches
2019 StandoutNatureNobel
Structural snapshots of TRPV1 reveal mechanism of polymodal functionality
2021 StandoutNobel
Mechanism of folding chamber closure in a group II chaperonin
2010 StandoutNatureNobel
One-state Downhill versus Conventional Protein Folding
2004
The Nucleosome
2004
Programmable design of orthogonal protein heterodimers
2018 StandoutNatureNobel
The PARP superfamily
2004
The Structure of the Polycystic Kidney Disease Channel PKD2 in Lipid Nanodiscs
2016
Protein Sequence Editing of SKN-1A/Nrf1 by Peptide:N-Glycanase Controls Proteasome Gene Expression
2019 StandoutNobel
Structure of the Mammalian Ribosomal 43S Preinitiation Complex Bound to the Scanning Factor DHX29
2013 StandoutNobel
Nuclear ADP-Ribosylation Reactions in Mammalian Cells: Where Are We Today and Where Are We Going?
2006
Architecture of an RNA Polymerase II Transcription Pre-Initiation Complex
2013 StandoutScienceNobel
Inhibition of NGLY1 Inactivates the Transcription Factor Nrf1 and Potentiates Proteasome Inhibitor Cytotoxicity
2017 StandoutNobel
In the light of directed evolution: Pathways of adaptive protein evolution
2009 StandoutNobel
Molecular architecture of the 26S proteasome holocomplex determined by an integrative approach
2012
Solution structure of p53 core domain: Structural basis for its instability
2006
Ligand-Dependent Equilibrium Fluctuations of Single Calmodulin Molecules
2009 Science
Structure of a Multipartite Protein-Protein Interaction Domain in Splicing Factor Prp8 and Its Link to Retinitis Pigmentosa
2007
Architecture and function of metallopeptidase catalytic domains
2013
Hydroxylation of the eukaryotic ribosomal decoding center affects translational accuracy
2014 StandoutNobel
Trapping a transition state in a computationally designed protein bottle
2015 StandoutScienceNobel
An Analysis of the Effects of 1HN−1HN Dipolar Couplings on the Measurement of Amide Bond Vector Orientations in Invisible Protein States by Relaxation Dispersion NMR
2009
How Fast-Folding Proteins Fold
2011 Science
Arabidopsis Transcription Factors: Genome-Wide Comparative Analysis Among Eukaryotes
2000 StandoutScience
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression
2012 StandoutNobel
Swinging Arms and Swinging Domains in Multifunctional Enzymes: Catalytic Machines for Multistep Reactions
2000
An Improved 15N Relaxation Dispersion Experiment for the Measurement of Millisecond Time-Scale Dynamics in Proteins
2007
Functional reconstitution of human eukaryotic translation initiation factor 3 (eIF3)
2011 StandoutNobel
Demonstration of a low-energy on-pathway intermediate in a fast-folding protein by kinetics, protein engineering, and simulation
2004
Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3
2008 StandoutNobel
Top-down design of protein architectures with reinforcement learning
2023 StandoutScienceNobel
The Protein Folding Problem
2008
Structural insights into TRPM8 inhibition and desensitization
2019 StandoutScienceNobel
Targeted Investigation of the Neandertal Genome by Array-Based Sequence Capture
2010 StandoutScienceNobel
Selective potentiation of Stat-dependent gene expression by collaborator of Stat6 (CoaSt6), a transcriptional cofactor
2006
Nonnative Interactions in the FF Domain Folding Pathway from an Atomic Resolution Structure of a Sparsely Populated Intermediate: An NMR Relaxation Dispersion Study
2011 StandoutNobel
Works of Mark D. Allen being referenced
Crystal Structure of a Superstable Mutant of Human p53 Core Domain
2004
The Structure of an FF Domain from Human HYPA/FBP11
2002
DNA recognition by β-sheets
1997
Molecular basis of histone H3K36me3 recognition by the PWWP domain of Brpf1
2010
The Structure of the Major Transition State for Folding of an FF Domain from Experiment and Simulation
2005
The Crystal Structure of AF1521 a Protein from Archaeoglobus fulgidus with Homology to the Non-histone Domain of MacroH2A
2003
The macro domain is an ADP‐ribose binding module
2005
Crystal Structure of the Malignant Brain Tumor (MBT) Repeats in Sex Comb on Midleg-like 2 (SCML2)
2003
Solution structure of the nonmethyl‐CpG‐binding CXXC domain of the leukaemia‐associated MLL histone methyltransferase
2006
Simulation and Experiment at High Temperatures: Ultrafast Folding of a Thermophilic Protein by Nucleation-condensation
2005
The catalytic domain of dihydrolipoyl acetyltransferase from the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus
1997
Solution Structure of the Kaposi's Sarcoma-associated Herpesvirus K3 N-terminal Domain Reveals a Novel E2-binding C4HC3-type RING Domain
2004
A novel mode of DNA recognition by a β-sheet revealed by the solution structure of the GCC-box binding domain in complex with DNA
1998
Electrostatic Interactions Contribute to Reduced Heat Capacity Change of Unfolding in a Thermophilic Ribosomal Protein L30e
2005
The Folding Mechanism of BBL: Plasticity of Transition-State Structure Observed within an Ultrafast Folding Protein Family
2009
The PUB Domain Functions as a p97 Binding Module in Human Peptide N-Glycanase
2006
Recognition of a Surface Loop of the Lipoyl Domain Underlies Substrate Channelling in the Pyruvate Dehydrogenase Multienzyme Complex
1996
Ultra-fast Barrier-limited Folding in the Peripheral Subunit-binding Domain Family
2005
Protein–protein interactions in the pyruvate dehydrogenase multienzyme complex: dihydrolipoamide dehydrogenase complexed with the binding domain of dihydrolipoamide acetyltransferase
1996
Designing an extracellular matrix protein with enhanced mechanical stability
2007
The peripheral subunit-binding domain of the dihydrolipoyl acetyltransferase component of the pyruvate dehydrogenase complex of Bacillus stearothermophilus: preparation and characterization of its binding to the dihydrolipoyl dehydrogenase component
1994
A high‐resolution structure of the EF‐hand domain of human polycystin‐2
2014
Structure of the Jab1/MPN Domain and Its Implications for Proteasome Function
2003
Principles of quasi-equivalence and Euclidean geometry govern the assembly of cubic and dodecahedral cores of pyruvate dehydrogenase complexes
1999