Citation Impact
Citing Papers
Control of Regulatory T Cell Development by the Transcription Factor Foxp3
2003 StandoutScienceNobel
A subset of natural killer cells achieves self-tolerance without expressing inhibitory receptors specific for self-MHC molecules
2005
PD-1 + regulatory T cells amplified by PD-1 blockade promote hyperprogression of cancer
2019 StandoutNobel
Early growth response gene 2 (Egr-2) controls the self-tolerance of T cells and prevents the development of lupuslike autoimmune disease
2008
NK Cell Responsiveness Is Tuned Commensurate with the Number of Inhibitory Receptors for Self-MHC Class I: The Rheostat Model
2009
T‐cell fate
1998
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
Hif-2α is not essential for cell-autonomous hematopoietic stem cell maintenance
2013 StandoutNobel
An integrated encyclopedia of DNA elements in the human genome
2012 StandoutNature
Expansion and Function of CD8+ T Cells Expressing Ly49 Inhibitory Receptors Specific for MHC Class I Molecules
2004 StandoutNobel
Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections
2005 StandoutNatureNobel
Elements of cancer immunity and the cancer–immune set point
2017 StandoutNature
Transcription initiation platforms and GTF recruitment at tissue-specific enhancers and promoters
2011
Transforming growth factor-β controls T helper type 1 cell development through regulation of natural killer cell interferon-γ
2005
Comparative analysis of the efficiency and specificity of myeloid-Cre deleting strains using ROSA-EYFP reporter mice
2014
Thymocyte expression of cathepsin L is essential for NKT cell development
2002
Expression and function of NK cell receptors in CD8+ T cells
2001
Dual Functions of Runx Proteins for Reactivating CD8 and Silencing CD4 at the Commitment Process into CD8 Thymocytes
2005
Early quantitative and functional deficiency of NK1+‐like thymocytes in the NOD mouse
1996
Oncogenic kinase signalling
2001 StandoutNature
In vivo kinetics of human natural killer cells: the effects of ageing and acute and chronic viral infection
2007
Regulatory T Cells
2000 StandoutNobel
Regulation of αβ/γδ T Cell Lineage Commitment and Peripheral T Cell Responses by Notch/RBP-J Signaling
2004 StandoutNobel
Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1
2007 StandoutNatureNobel
Lipid length controls antigen entry into endosomal and nonendosomal pathways for CD1b presentation
2002
Regulatory T Cells and Immune Tolerance
2008 StandoutNobel
Tissue-resident macrophages
2013 Standout
Cellular survival: a play in three Akts
1999 Standout
Role of the Biomolecular Energy Gap in Protein Design, Structure, and Evolution
2012 StandoutNobel
NKT cells: what's in a name?
2004
Interleukin-22-producing innate immune cells: new players in mucosal immunity and tissue repair?
2009
PD-1:PD-L inhibitory pathway affects both CD4+ and CD8+ T cells and is overcome by IL-2
2002 StandoutNobel
Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells
2010 Standout
Haematopoietic stem cells and early lymphoid progenitors occupy distinct bone marrow niches
2013 Nature
Involvement of inhibitory NKRs in the survival of a subset of memory-phenotype CD8+ T cells
2001
Thymic selection revisited: how essential is it?
2003
Molecular biology of NK T cell specificity and development
2000
Functions of natural killer cells
2008 Standout
'Coreceptor tuning': cytokine signals transcriptionally tailor CD8 coreceptor expression to the self-specificity of the TCR
2007
The unconventional lifestyle of NKT cells
2002
Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice
2003 StandoutNatureNobel
Human natural killer cell development
2006
Loss of β-Catenin Impairs the Renewal of Normal and CML Stem Cells In Vivo
2007
Regulation of T cell function by NK cell receptors for classical MHC class I molecules
2000
Lineage Tracing of Pf4-Cre Marks Hematopoietic Stem Cells and Their Progeny
2012
Enterochromaffin Cells Are Gut Chemosensors that Couple to Sensory Neural Pathways
2017 StandoutNobel
Critical role for the chemokine receptor CXCR6 in NK cell–mediated antigen-specific memory of haptens and viruses
2010
Genetic Evidence Supporting Selection of the Vα14i NKT Cell Lineage from Double-Positive Thymocyte Precursors
2005
Mouse NK1+ T cells
1995
Regulation and Function of the PD-L1 Checkpoint
2018 Standout
Endothelial and perivascular cells maintain haematopoietic stem cells
2012 Nature
The evolving tumor microenvironment: From cancer initiation to metastatic outgrowth
2023 Standout
Selection of phenotypically distinct NK1.1+ T cells upon antigen expression in the thymus or in the liver
1999
Recognition of lipid antigens by T cells
2005
An Alternate Pathway for CD4 T Cell Development: Thymocyte-Expressed MHC Class II Selects a Distinct T Cell Population
2005
Defective lymphoid development in mice lacking expression of the common cytokine receptor γ chain
1995
Early TCRα expression generates TCRαγ complexes that signal the DN-to-DP transition and impair development
2002
Extracellular Vesicle-Mediated Transfer of Genetic Information between the Hematopoietic System and the Brain in Response to Inflammation
2014
CD1d Endosomal Trafficking Is Independently Regulated by an Intrinsic CD1d-Encoded Tyrosine Motif and by the Invariant Chain
2001
Absolute requirement for the pre-T cell receptor α chain during NK1.1+ TCRα β cell development
1999
IFNAR1-Signalling Obstructs ICOS-mediated Humoral Immunity during Non-lethal Blood-Stage Plasmodium Infection
2016
Deciphering Hematopoietic Stem Cells in Their Niches: A Critical Appraisal of Genetic Models, Lineage Tracing, and Imaging Strategies
2013
Tuning of Antigen Sensitivity by T Cell Receptor-Dependent Negative Feedback Controls T Cell Effector Function in Inflamed Tissues
2014
Altered Development of CD8+ T Cell Lineages in Mice Deficient for the Tec Kinases Itk and Rlk
2006
Self-tolerance of natural killer cells
2006
Developmental program of mouse Vα14i NKT cells
2005
Neuro-Immune Interactions at Barrier Surfaces
2016
Intrathymic NKT cell development is blocked by the presence of α‐galactosylceramide
2003
Removing the Vertebrate-Specific TBP N Terminus Disrupts Placental β2m-Dependent Interactions with the Maternal Immune System
2002 StandoutNobel
Molecular determinants of TCR expression and selection
2001
Multiple defects in antigen presentation and T cell development by mice expressing cytoplasmic tail–truncated CD1d
2001
Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy
2016 StandoutNobel
Comprehensive Integration of Single-Cell Data
2019 Standout
Differential Requirements for Runx Proteins in CD4 Repression and Epigenetic Silencing during T Lymphocyte Development
2002
A new self: MHC-class-I-independent Natural-killer-cell self-tolerance
2005
NKT cells derive from double-positive thymocytes that are positively selected by CD1d
2001
Lineage fate and intense debate: myths, models and mechanisms of CD4- versus CD8-lineage choice
2008
Interleukin 15 Controls both Proliferation and Survival of a Subset of Memory-Phenotype CD8+ T Cells
2002
Dual modulation of cell survival and cell death by β 2 -adrenergic signaling in adult mouse cardiac myocytes
2001 StandoutNobel
Computational design of a synthetic PD-1 agonist
2021 StandoutNobel
β-Arrestin2 mediates the initiation and progression of myeloid leukemia
2012 StandoutNobel
Signaling Life and Death in the Thymus: Timing Is Everything
2003 Science
T cell fate specification and αβ/γδ lineage commitment
2001
A Subset of CD4 + Thymocytes Selected by MHC Class I Molecules
1994 Science
Cutting Edge: Ly49A Inhibits TCR/CD3-Induced Apoptosis and IL-2 Secretion
2001
RTP4 inhibits IFN-I response and enhances experimental cerebral malaria and neuropathology
2020 StandoutNobel
The Influence of CD1d in Postselection NKT Cell Maturation and Homeostasis
2005
Expression of T cell receptor βlocus in central nervous system neurons
2003
Characterization of TCR Gene Rearrangements During Adult Murine T Cell Development
1999
Transgenic Expression of Ly49A on T Cells Impairs a Specific Antitumor Response
2000
Genetically encoded reporters of protein kinase A activity reveal impact of substrate tethering
2001 StandoutNobel
CD4+CD25−LAG3+regulatory T cells controlled by the transcription factor Egr-2
2009 StandoutNobel
Multiplicity and plasticity of natural killer cell signaling pathways
2005
Major histocompatibility complex class I related molecules control the development of CD4+8- and CD4-8- subsets of natural killer 1.1+ T cell receptor-alpha/beta+ cells in the liver of mice.
1994
NK T Cell Precursors Exhibit Differential Cytokine Regulation and Require Itk for Efficient Maturation
2002
Cutting Edge: Influence of the TCR Vβ Domain on the Selection of Semi-Invariant NKT Cells by Endogenous Ligands
2006
REGULATION OF LYMPHOID DEVELOPMENT, DIFFERENTIATION, AND FUNCTION BY THE NOTCH PATHWAY
2005
An invariant V alpha 24-J alpha Q/V beta 11 T cell receptor is expressed in all individuals by clonally expanded CD4-8- T cells.
1994
The Biology of NKT Cells
2006 Standout
Inhibitory role of the transcription repressor Gfi1 in the generation of thymus-derived regulatory T cells
2013
Expression of CD1d Under the Control of a MHC Class Ia Promoter Skews the Development of NKT Cells, But Not CD8+ T Cells
2003
Cutting Edge: Stimulation with the Cognate Self-Antigen Induces Expression of the Ly49A Receptor on Self-Reactive T Cells Which Modulates Their Responsiveness
2003
PD-L1/B7H-1 Inhibits the Effector Phase of Tumor Rejection by T Cell Receptor (TCR) Transgenic CD8+ T Cells
2004 StandoutNobel
Cytotoxicity of fresh NK1.1+ T cell receptor alpha/beta+ thymocytes against a CD4+8+ thymocyte population associated with intact Fas antigen expression on the target.
1994
The lymphoproliferative defect in CTLA-4–deficient mice is ameliorated by an inhibitory NK cell receptor
2002 StandoutNobel
Regulation of the Natural Killer Cell Receptor Repertoire
2001
Viral and Bacterial Infections Induce Expression of Multiple NK Cell Receptors in Responding CD8+ T Cells
2002
A dose effect of IL-7 on thymocyte development
2004
Membrane Lymphotoxin Is Required for the Development of Different Subpopulations of NK T Cells
2000
Targeted Expression of Human CD1d in Transgenic Mice Reveals Independent Roles for Thymocytes and Thymic APCs in Positive and Negative Selection of Vα14i NKT Cells
2005
Deficiency in β2-Microglobulin, But Not CD1, Accelerates Spontaneous Lupus Skin Disease While Inhibiting Nephritis in MRL-FaslprMice: An Example of Disease Regulation at the Organ Level
2001
Evidence That γδ versus αβ T Cell Fate Determination Is Initiated Independently of T Cell Receptor Signaling
2001
Unraveling a Revealing Paradox
2003
Deficiency of PTEN in Jurkat T Cells Causes Constitutive Localization of Itk to the Plasma Membrane and Hyperresponsiveness to CD3 Stimulation
2000
Premature Expression of T Cell Receptor (Tcr)αβ Suppresses Tcrγδ Gene Rearrangement but Permits Development of γδ Lineage T Cells
2000
Control of T Cell Development In Vivo by Subdomains Within the IL-7 Receptor α-Chain Cytoplasmic Tail
2001
An invariant T cell receptor alpha chain is used by a unique subset of major histocompatibility complex class I-specific CD4+ and CD4-8- T cells in mice and humans.
1994
CD1d-Restricted Immunoglobulin G Formation to GPI-Anchored Antigens Mediated by NKT Cells
1999 Science
Simultaneous inhibition of two regulatory T-cell subsets enhanced Interleukin-15 efficacy in a prostate tumor model
2012 StandoutNobel
Tracking the Response of Natural Killer T Cells to a Glycolipid Antigen Using Cd1d Tetramers
2000
Cutting Edge: Regulation of Uterine NKT Cells by a Fetal Class I Molecule Other Than CD1
2001
Expansion and long-range differentiation of the NKT cell lineage in mice expressing CD1d exclusively on cortical thymocytes
2005
Emergence of CD8+ T Cells Expressing NK Cell Receptors in Influenza A Virus-Infected Mice
2000
Cytokine signal transduction is suppressed in preselection double-positive thymocytes and restored by positive selection
2006
Interactions between double positive thymocytes and high affinity ligands presented by cortical epithelial cells generate double negative thymocytes with T cell regulatory activity
2002
Restoration of NK T Cell Development infyn-Mutant Mice by a TCR Reveals a Requirement for Fyn During Early NK T Cell Ontogeny
2004
DOCK2 Is Required in T Cell Precursors for Development of Vα14 NK T Cells
2006
Adult hematopoietic stem cells lacking Hif-1α self-renew normally
2016 StandoutNobel
The Mouse Cd1d-Restricted Repertoire Is Dominated by a Few Autoreactive T Cell Receptor Families
2001
Lack of CD47 on nonhematopoietic cells induces split macrophage tolerance to CD47nullcells
2007
Quantitative Impact of Thymic Clonal Deletion on the T Cell Repertoire
1997
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
A Natural Killer T (NKT) Cell Developmental Pathway Involving a Thymus-dependent NK1.1−CD4+ CD1d-dependent Precursor Stage
2002
Msx2-interacting nuclear target protein (Mint) deficiency reveals negative regulation of early thymocyte differentiation by Notch/RBP-J signaling
2007 StandoutNobel
Cutting Edge: Contribution of NK Cells to the Homing of Thymic CD4+NKT Cells to the Liver
2000
14-3-3 Proteins: Structure, Function, and Regulation
2000 Standout
Precision glycocalyx editing as a strategy for cancer immunotherapy
2016 StandoutNobel
Positive selection of mouse NK1+ T cells by CD1-expressing cortical thymocytes.
1995
Absence of Programmed Death Receptor 1 Alters Thymic Development and Enhances Generation of CD4/CD8 Double-Negative TCR-Transgenic T Cells
2003 StandoutNobel
Proenkephalin+regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function
2020 StandoutNobel
A Thymic Precursor to the NK T Cell Lineage
2002 Science
Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+regulatory T cells, evoking antitumor immune responses in humans
2013 StandoutNobel
CD8+ T Cells Rapidly Acquire NK1.1 and NK Cell-Associated Molecules Upon Stimulation In Vitro and In Vivo
2000
Essential requirement of an invariant V alpha 14 T cell antigen receptor expression in the development of natural killer T cells.
1996
The Src Family Tyrosine Kinase Fyn Regulates Natural Killer T Cell Development
1999
A unique lymphotoxin αβ-dependent pathway regulates thymic emigration of Vα14 invariant natural killer T cells
2006
Programmed death-1 concentration at the immunological synapse is determined by ligand affinity and availability
2007 StandoutNobel
CD4+ T Cells Prevent Spontaneous Experimental Autoimmune Encephalomyelitis in Anti–Myelin Basic Protein T Cell Receptor Transgenic Mice
1998 Nobel
PapA1 and PapA2 are acyltransferases essential for the biosynthesis of theMycobacterium tuberculosisvirulence factor Sulfolipid-1
2007 StandoutNobel
The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance
2011
Increased interleukin 4 and immunoglobulin E production in transgenic mice overexpressing NK1 T cells.
1996
The Tec Family Tyrosine Kinases Itk and Rlk Regulate the Development of Conventional CD8+ T Cells
2006
Development of Valpha4+ NK T cells in the early stages of embryogenesis.
1996
NIK-dependent RelB Activation Defines a Unique Signaling Pathway for the Development of Vα14i NKT Cells
2003
Identification, activation, and selectivein vivoablation of mouse NK cells via NKp46
2007
CD1-restricted CD4+ T cells in major histocompatibility complex class II-deficient mice.
1995
A distinct subpopulation of CD25−T-follicular regulatory cells localizes in the germinal centers
2017 StandoutNobel
A Cell-Type Specific CD1d Expression Program Modulates Invariant NKT Cell Development and Function
2006
γδ Cells: A Right Time and a Right Place for a Conserved Third Way of Protection
2000
The Pten/PI3K pathway governs the homeostasis of Vα14iNKT cells
2006 StandoutNobel
Innate or Adaptive Immunity? The Example of Natural Killer Cells
2011 StandoutScience
CD27 Dissects Mature NK Cells into Two Subsets with Distinct Responsiveness and Migratory Capacity
2006
Characterization of the early stages of thymic NKT cell development
2005
CD1 Recognition by Mouse NK1 + T Lymphocytes
1995 StandoutScience
Requirements for CD1d Recognition by Human Invariant Vα24+ CD4−CD8− T Cells
1997
Defective Lymphoid Development in Mice Lacking Jak3
1995 StandoutScienceNobel
CD1d-expressing Dendritic Cells but Not Thymic Epithelial Cells Can Mediate Negative Selection of NKT Cells
2003
Differential Roles of Cytokine Receptors in the Development of Epidermal γδ T Cells
2001 StandoutNobel
Differential Expression of Leukocyte Receptor Complex-Encoded Ig-Like Receptors Correlates with the Transition from Effector to Memory CTL
2001
Works of Mark Coles being referenced
Transgenic mice with hematopoietic and lymphoid specific expression of Cre
2003
Tyrosine kinase receptor RET is a key regulator of Peyer’s Patch organogenesis
2007 Nature
MicroRNA-155 induction via TNF-α and IFN-γ suppresses expression of programmed death ligand-1 (PD-L1) in human primary cells
2017
IL7‐hCD25 and IL7‐Cre BAC transgenic mouse lines: New tools for analysis of IL‐7 expressing cells
2009
Hierarchical Interactions of Control Elements Determine CD8α Gene Expression in Subsets of Thymocytes and Peripheral T Cells
1998
Variegated Expression of CD8α Resulting from In Situ Deletion of Regulatory Sequences
2002
Fibroblasts as immune regulators in infection, inflammation and cancer
2021
Dynamic Imaging of Experimental Leishmania donovani-Induced Hepatic Granulomas Detects Kupffer Cell-Restricted Antigen Presentation to Antigen-Specific CD8+ T Cells
2010
The Developmental Fate of T Cells Is Critically Influenced by TCRγδ Expression
1998
Memory CD8 T lymphocytes express inhibitory MHC-specific Ly49 receptors
2000
The basis for self-tolerance of natural killer cells in beta2-microglobulin- and TAP-1- mice.
1997
Early Onset of CD8 Transgene Expression Inhibits the Transition from DN3 to DP Thymocytes
2000
Class I MHC molecules on hematopoietic cells can support intrathymic positive selection of T cell receptor transgenic T cells
1999
Turnover and Proliferation of NK Cells in Steady State and Lymphopenic Conditions
2004
Bad Can Act as a Key Regulator of T Cell Apoptosis and T Cell Development
1999
NK1.1+ T Cells in the Liver Arise in the Thymus and Are Selected by Interactions with Class I Molecules on CD4+CD8+ Cells
2000
Positive selection of V beta 8+ CD4-8- thymocytes by class I molecules expressed by hematopoietic cells.
1993
Alveolar Macrophages Transport Pathogens to Lung Draining Lymph Nodes
2009
Role of T and NK cells and IL7/IL7r interactions during neonatal maturation of lymph nodes
2006
Differential RET Signaling Pathways Drive Development of the Enteric Lymphoid and Nervous Systems
2012
Defective Development of γ/δ T Cells in Interleukin 7 Receptor–Deficient Mice Is Due to Impaired Expression of T Cell Receptor γ Genes
1999
Class I dependence of the development of CD4+ CD8- NK1.1+ thymocytes.
1994