Citation Impact
Citing Papers
Tailoring cAMP-signalling responses through isoform multiplicity
1997
Go-protein α-Subunits Activate Mitogen-activated Protein Kinase via a Novel Protein Kinase C-dependent Mechanism
1996 StandoutNobel
Thalamocortical Oscillations in the Sleeping and Aroused Brain
1993 StandoutScience
Adenylyl cyclases
1992 StandoutNobel
Adenosine promotes burst activity in guinea‐pig geniculocortical neurones through two different ionic mechanisms.
1992
Insights into G Protein Structure, Function, and Regulation
2003
Complexity and Diversity of Mammalian Adenylyl Cyclases
1996 Nobel
G Protein-coupled Receptors Mediate Two Functionally Distinct Pathways of Tyrosine Phosphorylation in Rat 1a Fibroblasts
1997 StandoutNobel
Phosphorylation of Gzα by Protein Kinase C Blocks Interaction with the βγ Complex
1995
Gβγ Subunits Mediate Mitogen-activated Protein Kinase Activation by the Tyrosine Kinase Insulin-like Growth Factor 1 Receptor
1995 StandoutNobel
The Role of GTP-Binding Proteins in Signal Transduction: From the Sublimely Simple to the Conceptually Complex
1992 StandoutNobel
Phosphorylation and Desensitization of the Human β1-Adrenergic Receptor
1995 StandoutNobel
Depletion of intracellular calcium stores activates a calcium current in mast cells
1992 StandoutNature
Challenges and solutions to ultra-high-throughput screening assay miniaturization: submicroliter fluid handling
2000
Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase
2014 StandoutNature
Phosphorylation of the Type 1A Angiotensin II Receptor by G Protein-coupled Receptor Kinases and Protein Kinase C
1996 StandoutNobel
Effects of nitric oxide-containing compounds on increases in cytosolic ionized Ca2+ and on aggregation of human platelets
1993
Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP
2013 Nature
Nitric oxide controls oscillatory activity in thalamocortical neurons
1992
Ras-dependent Mitogen-activated Protein Kinase Activation by G Protein-coupled Receptors
1997 StandoutNobel
β2-Adrenergic Receptor Signaling and Desensitization Elucidated by Quantitative Modeling of Real Time cAMP Dynamics
2007 StandoutNobel
CGRP-induced activation of KATP channels in follicular Xenopus oocytes
1994
Endothelium-derived relaxant factor inhibits platelet activation
1987
Receptors for ADP on human blood platelets
1994
Protein Kinase A-mediated Phosphorylation of the β2-Adrenergic Receptor Regulates Its Coupling to Gs and Gi
2002 StandoutNobel
Role of c-Src Tyrosine Kinase in G Protein-coupled Receptorand Gβγ Subunit-mediated Activation of Mitogen-activated Protein Kinases
1996 StandoutNobel
Gβγ Subunits Mediate Src-dependent Phosphorylation of the Epidermal Growth Factor Receptor
1997 StandoutNobel
Identification of the platelet ADP receptor targeted by antithrombotic drugs
2001 StandoutNatureNobel
GTP‐binding protein‐activator sequences in the insulin receptor
1993
Role of guanylyl cyclase and cGMP-dependent protein kinase in long-term potentiation
1994 StandoutNatureNobel
Differential Regulation of Dopamine D1A Receptor Responsiveness by Various G Protein-coupled Receptor Kinases
1996 StandoutNobel
RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor
1998 StandoutNature
Molecular Characterization of a Functional cDNA Encoding the Serotonin 1c Receptor
1988 StandoutScienceNobel
Phorbol ester-induced stimulation and phosphorylation of adenylyl cyclase 2.
1994
Multiple second messenger pathways of alpha-adrenergic receptor subtypes expressed in eukaryotic cells.
1990 StandoutNobel
α2-Adrenergic Receptor Stimulation Mobilizes Intracellular Ca2+ in Human Erythroleukemia Cells
1989
Cloning and expression of a widely distributed (type IV) adenylyl cyclase.
1991 StandoutNobel
G protein beta gamma subunits. Simplified purification and properties of novel isoforms.
1994 StandoutNobel
Homologous desensitization of HEL cell thrombin receptors. Distinguishable roles for proteolysis and phosphorylation.
1992
Kinetics of thrombin receptor cleavage on intact cells. Relation to signaling
1993 StandoutNobel
Molecular cloning and characterization of a Ca2+/calmodulin-insensitive adenylyl cyclase from rat brain.
1991 StandoutNobel
Genetically encoded reporters of protein kinase A activity reveal impact of substrate tethering
2001 StandoutNobel
Kinetics of "P"-site-mediated inhibition of adenylyl cyclase and the requirements for substrate.
1990
Inositol trisphosphate, a novel second messenger in cellular signal transduction
1984 StandoutNature
Ectopic Expression of the Serotonin 1c Receptor and the Triggering of Malignant Transformation
1989 StandoutScienceNobel
Expression and characterization of calmodulin-activated (type I) adenylylcyclase
1991 StandoutNobel
Thyrotropin-releasing hormone stimulates MAP kinase activity in GH3 cells by divergent pathways. Evidence of a role for early tyrosine phosphorylation.
1994
β-arrestin- but not G protein-mediated signaling by the “decoy” receptor CXCR7
2009 StandoutNobel
G protein beta gamma subunits stimulate phosphorylation of Shc adapter protein.
1995 StandoutNobel
The G226A mutant of Gs alpha highlights the requirement for dissociation of G protein subunits.
1992 StandoutNobel
The disaggregation theory of signal transduction revisited: further evidence that G proteins are multimeric and disaggregate to monomers when activated.
1993 StandoutNobel
The 5HT2 receptor defines a family of structurally distinct but functionally conserved serotonin receptors.
1990 StandoutNobel
G protein beta gamma subunits synthesized in Sf9 cells. Functional characterization and the significance of prenylation of gamma
1992 StandoutNobel
Mechanism of cyclic GMP inhibition of inositol phosphate formation in rat aorta segments and cultured bovine aortic smooth muscle cells.
1990 StandoutNobel
Inositol phospholipid turnover in PAF transmembrane signalling
1991
Receptor class desensitization of leukocyte chemoattractant receptors.
1991
Regulation of purified type I and type II adenylylcyclases by G protein beta gamma subunits.
1993 StandoutNobel
Inhibitory action of cyclic GMP on secretion, polyphosphoinositide hydrolysis and calcium mobilization in thrombin-stimulated human platelets
1986
Generation of Calcium Oscillations in Fibroblasts by Positive Feedback Between Calcium and IP 3
1991 StandoutScienceNobel
Caged nitric oxide. Stable organic molecules from which nitric oxide can be photoreleased.
1994 StandoutNobel
Atrial natriuretic peptide binding, cross-linking, and stimulation of cyclic GMP accumulation and particulate guanylate cyclase activity in cultured cells.
1988 StandoutNobel
Antagonism of Catecholamine Receptor Signaling by Expression of Cytoplasmic Domains of the Receptors
1993 StandoutScienceNobel
Structure and expression of the rat inositol 1,4,5-trisphosphate receptor.
1990 StandoutNobel
Heterotrimeric G proteins in synaptoneurosome membranes are crosslinked by p-phenylenedimaleimide, yielding structures comparable in size to crosslinked tubulin and F-actin.
1992 StandoutNobel
Relationship of thyrotropin-releasing hormone-induced spike and plateau phases in cytosolic free Ca2+ concentrations to hormone secretion. Selective blockade using ionomycin and nifedipine.
1984
Inhibition of Adenylyl Cyclase by G iα
1993 StandoutScienceNobel
Distinct patterns of bidirectional regulation of mammalian adenylyl cyclases.
1994 StandoutNobel
Molecular Basis for Interactions of G Protein βγ Subunits with Effectors
1998 StandoutScienceNobel
Isolation and characterization of a novel cardiac adenylylcyclase cDNA.
1992
The interaction of lithium with thyrotropin-releasing hormone-stimulated lipid metabolism in GH3 pituitary tumour cells. Enhancement of stimulated 1,2-diacylglycerol formation
1984
Role of cGMP and cGMP-dependent protein kinase in nitrovasodilator inhibition of agonist-evoked calcium elevation in human platelets.
1992
Chaotic Mixer for Microchannels
2002 StandoutScience
Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide.
1990 Standout
A Region of Adenylyl Cyclase 2 Critical for Regulation by G Protein βγ Subunits
1995 StandoutScienceNobel
Prostaglandin F2α stimulates phosphatidylinositol turnover and increases the cellular content of 1,2‐diacylglycerol in confluent resting swiss 3T3 cells
1984
Type-Specific Regulation of Adenylyl Cyclase by G Protein βγ Subunits
1991 StandoutScienceNobel
Evidence that phospholipid turnover is the signal transducing system coupled to serotonin-S2 receptor sites.
1985
Works of Mark Bushfield being referenced
Cation and structural requirements for P site-mediated inhibition of adenylate cyclase.
1989
Thyrotropin-releasing hormone-stimulated [3H]inositol metabolism in GH3 pituitary tumor cells. Studies with lithium.
1984
The application of high-throughput screening to novel lead discovery
1998
Changes in the phosphorylation state of the inhibitory guanine‐nucleotide‐binding protein Gi‐2 in hepatocytes from lean (Fa/Fa) and obese (fa/fa) Zucker rats
1990
Regulation of platelet cytosolic free calcium by cyclic nucleotides and protein kinase C
1985
Streptozotocin-induced diabetes elicits the phosphorylation of hepatocyte Gi2α at the protein kinase C site but not at the protein kinase A-controlled site
1996
Regulation of the phosphorylation state of Gi2 in intact rat hepatocytes
1990
Regulation of adenylate cyclase by adenosine: characterization of the P-site
1990
Agonist-Induced Inositol Phospholipid Metabolism and Ca++ Flux in Human Platelet Activation
1985
Hormonal regulation of Gi2 α-subunit phosphorylation in intact hepatocytes
1990
Diabetes-induced alterations in the expression, functioning and phosphorylation state of the inhibitory guanine nucleotide regulatory protein Gi-2 in hepatocytes
1990
Possible mechanisms of the potentiation of blood-platelet activation by adrenaline
1987
Okadaic acid identifies a phosphorylation/dephosphorylation cycle controlling the inhibitory guanine-nucleotide-binding regulatory protein Gi2
1991