Citation Impact
Citing Papers
β-Arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2
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A unique mechanism of β-blocker action: Carvedilol stimulates β-arrestin signaling
2007 StandoutNobel
Prostaglandin F 2α elevates blood pressure and promotes atherosclerosis
2009
Human Epidermal Growth Factor Receptor 2 Assessment in a Case-Control Study: Comparison of Fluorescence In Situ Hybridization and Quantitative Reverse Transcription Polymerase Chain Reaction Performed by Central Laboratories
2010
Reliability of Human Epidermal Growth Factor Receptor 2 Immunohistochemistry in Breast Core Needle Biopsies
2010
HER2 in situ hybridization in breast cancer: clinical implications of polysomy 17 and genetic heterogeneity
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Very high quantitative tumor HER2 content and outcome in early breast cancer
2011
Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial
2010 Standout
A Novel Subtype of the Prostacyclin Receptor Expressed in the Central Nervous System
1996 StandoutNobel
Comparison of Central HER2 Testing With Quantitative Total HER2 Expression and HER2 Homodimer Measurements Using a Novel Proximity-Based Assay
2010
The RNA-binding Protein HuR Opposes the Repression of ERBB-2 Gene Expression by MicroRNA miR-331-3p in Prostate Cancer Cells
2011
Effects of the Change in Cutoff Values for Human Epidermal Growth Factor Receptor 2 Status by Immunohistochemistry and Fluorescence In Situ Hybridization: A Study Comparing Conventional Brightfield Microscopy, Image Analysis-Assisted Microscopy, and Interobserver Variation
2011
Recommendations for Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer: American Society of Clinical Oncology/College of American Pathologists Clinical Practice Guideline Update
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Identification of a subpopulation of metastatic breast cancer patients with very high HER2 expression levels and possible resistance to trastuzumab
2011
Cox-2-Selective Inhibitors: The New Super Aspirins
1999
The human olfactory receptor gene family
2004 StandoutNobel
Prostaglandin Endoperoxide H Synthases-1 and -2
1996
Fatty Acid Substrate Specificities of Human Prostaglandin-endoperoxide H Synthase-1 and −2
1995
Activation of FP Prostanoid Receptor Isoforms Leads to Rho-mediated Changes in Cell Morphology and in the Cell Cytoskeleton
1999
Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration
1995 StandoutNobel
Neuronal-specific expression of human copper-zinc superoxide dismutase gene in transgenic mice: animal model of gene dosage effects in Down's syndrome
1991
Chemoattractant Receptor-Homologous Molecule Expressed on Th2 Cells Activation in Vivo Increases Blood Leukocyte Counts and Its Blockade Abrogates 13,14-Dihydro-15-keto-prostaglandin D2-Induced Eosinophilia in Rats
2003
A Single Amino Acid Difference between Cyclooxygenase-1 (COX-1) and −2 (COX-2) Reverses the Selectivity of COX-2 Specific Inhibitors
1996
Different Intracellular Locations for Prostaglandin Endoperoxide H Synthase-1 and −2
1995
Distribution and function of prostanoid receptors: studies from knockout mice
2000
Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2
2004 StandoutNature
Assembly of the Warfarin-sensitive Vitamin K 2,3-Epoxide Reductase Enzyme Complex in the Endoplasmic Reticulum Membrane
1997
Pro-resolving lipid mediators are leads for resolution physiology
2014 StandoutNature
Positioning prostanoids of the D and J series in the immunopathogenic scheme
2005
Differential Affinities of Visual Arrestin, βArrestin1, and βArrestin2 for G Protein-coupled Receptors Delineate Two Major Classes of Receptors
2000
The Biochemical, Molecular, and Genomic Aspects of Leukotriene C4 Synthase
1999
Intracellular compartmentalization of leukotriene synthesis: unexpected nuclear secrets
2001
Neuronal oxidative damage from activated innate immunity is EP2 receptor‐dependent
2002
Lipoxygenases: Occurrence, Functions, Catalysis, and Acquisition of Substrate
1999
JAZ repressor proteins are targets of the SCFCOI1 complex during jasmonate signalling
2007 StandoutNature
Inhibition of human colon cancer cell growth by selective inhibition of cyclooxygenase-2.
1997
The multilayered complexity of ceRNA crosstalk and competition
2014 StandoutNature
Comparison of Structural Stabilities of Prostaglandin H Synthase-1 and -2
1998
The Interaction of Arginine 106 of Human Prostaglandin G/H Synthase-2 with Inhibitors Is Not a Universal Component of Inhibition Mediated by Nonsteroidal Anti-inflammatory Drugs
1997
A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1
2011 StandoutNatureNobel
Prostaglandins as modulators of immunity
2002
Efficacy of antileukotriene agents in asthma management
2001
c-Kit Ligand Mediates Increased Expression of Cytosolic Phospholipase A2, Prostaglandin Endoperoxide Synthase-1, and Hematopoietic Prostaglandin D2 Synthase and Increased IgE-dependent Prostaglandin D2 Generation in Immature Mouse Mast Cells
1995
Cloning, Expression, and Up-regulation of Inducible Rat Prostaglandin E Synthase during Lipopolysaccharide-induced Pyresis and Adjuvant-induced Arthritis
2001
Conversion of Prostaglandin G/H Synthase-1 into an Enzyme Sensitive to PGHS-2-selective Inhibitors by a Double His513→ Arg and Ile523→ Val Mutation
1997
Subcellular Localization of Prostaglandin Endoperoxide H Synthases-1 and -2 by Immunoelectron Microscopy
1998
Regulation of Ferroptotic Cancer Cell Death by GPX4
2014 Standout
The development of allergic inflammation
2008 StandoutNature
The structural basis of aspirin activity inferred from the crystal structure of inactivated prostaglandin H2 synthase
1995
Glial and neuronal control of brain blood flow
2010 StandoutNature
A β-arrestin 2 Signaling Complex Mediates Lithium Action on Behavior
2008 StandoutNobel
Immunity, Inflammation, and Cancer
2010 Standout
Epoxyeicosatrienoic Acids Function as Selective, Endogenous Antagonists of Native Thromboxane Receptors: Identification of a Novel Mechanism of Vasodilation
2008
Taking dendritic cells into medicine
2007 StandoutNatureNobel
Improved protein structure prediction using potentials from deep learning
2020 StandoutNatureNobel
Prostaglandin endoperoxide synthases-1 and -2
1995
A Novel Subtype of Prostacyclin Receptor in the Central Nervous System
1999 StandoutNobel
A second class of chemosensory receptors in the olfactory epithelium
2006 NatureNobel
EP4 prostanoid receptor‐mediated vasodilatation of human middle cerebral arteries
2004
Prostaglandin E Receptor Subtypes in Cultured Rat Microglia and Their Role in Reducing Lipopolysaccharide‐Induced Interleukin‐1 β Production
1999
Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse
1995 StandoutNobel
Subcellular Localization of β-Arrestins Is Determined by Their Intact N Domain and the Nuclear Export Signal at the C Terminus
2003
Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents
1996 StandoutNature
Insight into prostaglandin, leukotriene, and other eicosanoid functions using mice with targeted gene disruptions☆
1999
Cellular regulation of prostaglandin H synthase catalysis
1998
Colocalization of Prostacyclin Synthase with Prostaglandin H Synthase-1 (PGHS-1) but Not Phorbol Ester-induced PGHS-2 in Cultured Endothelial Cells
2000
Association of a New-Type Prostaglandin D2 Receptor CRTH2 with Circulating T Helper 2 Cells in Patients with Atopic Dermatitis
2002
The structure and function of lipoxygenase
1994
Crystal structure of misoprostol bound to the labor inducer prostaglandin E2 receptor
2018
Prostaglandin D2 and sleep regulation
1999
Membrane Fluidity Is a Key Modulator of Membrane Binding, Insertion, and Activity of 5-Lipoxygenase
2005
PGF2α FP Receptor Contributes to Brain Damage Following Transient Focal Brain Ischemia
2009
Cloning of a Carboxyl-terminal Isoform of the Prostanoid FP Receptor
1997
The Molecular Architecture of Odor and Pheromone Sensing in Mammals
2000 StandoutNobel
Identification and Characterization of a Novel Microsomal Enzyme with Glutathione-dependent Transferase and Peroxidase Activities
1997
Selective modulation of chemokinesis, degranulation, and apoptosis in eosinophils through the PGD2 receptors CRTH2 and DP
2001
Colorectal cancer prevention and treatment by inhibition of cyclooxygenase-2
2001
Mast cells and eicosanoid mediators: a system of reciprocal paracrine and autocrine regulation
2007
The N-terminal “β-Barrel” Domain of 5-Lipoxygenase Is Essential for Nuclear Membrane Translocation
2001
Arginine 120 of Prostaglandin G/H Synthase-1 Is Required for the Inhibition by Nonsteroidal Anti-inflammatory Drugs Containing a Carboxylic Acid Moiety
1995
Human prostacyclin receptor
2002
β-Arrestin 1 and 2 differentially regulate heptahelical receptor signaling and trafficking
2001 StandoutNobel
The DP receptor, allergic inflammation and asthma
2003
Distinct conformational changes in β-arrestin report biased agonism at seven-transmembrane receptors
2008 StandoutNobel
Prostanoid Receptors: Structures, Properties, and Functions
1999 Standout
Lack of tactile pain (allodynia) in lipocalin-type prostaglandin D synthase-deficient mice
1999
Bicyclo[2.2.1]heptane and 6,6-Dimethylbicyclo[3.1.1]heptane Derivatives: Orally Active, Potent, and Selective Prostaglandin D2 Receptor Antagonists
1997
Leukocyte lipid body formation and eicosanoid generation: cyclooxygenase-independent inhibition by aspirin.
1996 StandoutNobel
Lipoxygenase and Leukotriene Pathways: Biochemistry, Biology, and Roles in Disease
2011
Cyclooxygenases: Structural, Cellular, and Molecular Biology
2000 Standout
A Second Leukotriene B4 Receptor, Blt2
2000
Independent β-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2
2003 StandoutNobel
Lipocalin-Type Prostaglandin D Synthase in Essential Hypertension
2002
Protein Analysis by Shotgun/Bottom-up Proteomics
2013
Expression of prostaglandin G/H synthase-1 and -2 protein in human colon cancer.
1995
Prostanoid Receptors: Subtypes and Signaling
2001
Olfactory neurons expressing transient receptor potential channel M5 (TRPM5) are involved in sensing semiochemicals
2007 StandoutNobel
β-Arrestin2-mediated inotropic effects of the angiotensin II type 1A receptor in isolated cardiac myocytes
2006 StandoutNobel
β-arrestin- but not G protein-mediated signaling by the “decoy” receptor CXCR7
2009 StandoutNobel
G Protein–Coupled Prostanoid Receptors and the Kidney
2001
Prostaglandins and Leukotrienes: Advances in Eicosanoid Biology
2001 StandoutScience
Motor Neuron Degeneration in Mice that Express a Human Cu,Zn Superoxide Dismutase Mutation
1994 StandoutScience
β-Arrestin1 modulates lymphoid enhancer factor transcriptional activity through interaction with phosphorylated dishevelled proteins
2001 StandoutNobel
Simulations of the Large Kinetic Isotope Effect and the Temperature Dependence of the Hydrogen Atom Transfer in Lipoxygenase
2004 StandoutNobel
Dual Inhibition of β-Adrenergic and Angiotensin II Receptors by a Single Antagonist
2003
Prevention of Allergic Inflammation by a Novel Prostaglandin Receptor Antagonist, S-5751
2001
Expression of lipocalin-type prostaglandin D synthase (β-trace) in human heart and its accumulation in the coronary circulation of angina patients
1997
The mouse olfactory receptor gene family
2004 StandoutNobel
Expression and selective inhibition of the constitutive and inducible forms of human cyclo-oxygenase
1995
Prostaglandin D2 Selectively Induces Chemotaxis in T Helper Type 2 Cells, Eosinophils, and Basophils via Seven-Transmembrane Receptor Crth2
2001
Specificity and Sensitivity of a Human Olfactory Receptor Functionally Expressed in Human Embryonic Kidney 293 Cells andXenopus LaevisOocytes
1999
Functional antagonism of different G protein-coupled receptor kinases for β-arrestin-mediated angiotensin II receptor signaling
2005 StandoutNobel
Cyclosporine A-induced hypertension involves synapsin in renal sensory nerve endings
2000 StandoutNobel
Baking Reduces Prostaglandin, Resolvin, and Hydroxy-Fatty Acid Content of Farm-Raised Atlantic Salmon (Salmo salar)
2011
Cancer Chemopreventive Activity of Resveratrol, a Natural Product Derived from Grapes
1997 StandoutScience
Activation and targeting of extracellular signal-regulated kinases by β-arrestin scaffolds
2001 StandoutNobel
Activation of the D prostanoid 1 receptor suppresses asthma by modulation of lung dendritic cell function and induction of regulatory T cells
2007
Neural Control of Renal Function*
2020
The Pharmacology of the Ductus Arteriosus
1998
Developmental Changes in Prostaglandin E2Receptor Subtypes in Porcine Ductus Arteriosus
1999
HER2 and Chromosome 17 Effect on Patient Outcome in the N9831 Adjuvant Trastuzumab Trial
2010
Airway smooth muscle prostaglandin-EP1 receptors directly modulate 2-adrenergic receptors within a unique heterodimeric complex
2006
Prostaglandin D2 is a potent chemoattractant for human eosinophils that acts via a novel DP receptor
2001
The Kinetic Factors That Determine the Affinity and Selectivity for Slow Binding Inhibition of Human Prostaglandin H Synthase 1 and 2 by Indomethacin and Flurbiprofen
1996
Tissue-specific contributions of Tmem79 to atopic dermatitis and mast cell-mediated histaminergic itch
2018 StandoutNobel
Selective engagement of G protein coupled receptor kinases (GRKs) encodes distinct functions of biased ligands
2009 StandoutNobel
Prostaglandins and Inflammation
2011 Standout
Failure of ductus arteriosus closure and remodeling in neonatal mice deficient in cyclooxygenase-1 and cyclooxygenase-2
2001 StandoutNobel
Noncovalent Cell Surface Engineering: Incorporation of Bioactive Synthetic Glycopolymers into Cellular Membranes
2008 StandoutNobel
Expression of the prostaglandin F receptor (FP) gene along the mouse genitourinary tract
2003
Transduction of Receptor Signals by ß-Arrestins
2005 StandoutScienceNobel
Chemical Glycoproteomics
2016 StandoutNobel
Desensitization, internalization, and signaling functions of β-arrestins demonstrated by RNA interference
2003 StandoutNobel
Prostaglandin D2 Inhibits Airway Dendritic Cell Migration and Function in Steady State Conditions by Selective Activation of the D Prostanoid Receptor 1
2003
Works of Mark Abramovitz being referenced
Overexpression of human prostaglandin G/H synthase-1 and -2 by recombinant vaccinia virus: inhibition by nonsteroidal anti-inflammatory drugs and biosynthesis of 15-hydroxyeicosatetraenoic acid.
1994
Chromosomal localization of the human prostanoid receptor gene family
1995
Molecular cloning and functional characterization of murine cysteinyl-leukotriene 1 (CysLT1) receptors11Abbreviations: LT, leukotriene; hCysLT1R, human cysteinyl-leukotriene receptor (subtype 1); mCysLT1R, mouse cysteinyl-leukotriene receptor (subtype 1); CysLT2R, cysteinyl-leukotriene receptor (subtype 2); HEK, human embryonic kidney; ORF, open reading frame; RT-PCR, reverse transcription-polymerase chain reaction; and RACE, rapid amplification of cDNA ends.
2001
Differential Signaling of Cysteinyl Leukotrienes and a Novel Cysteinyl Leukotriene Receptor 2 (CysLT2) Agonist, N-Methyl-Leukotriene C4, in Calcium Reporter and β Arrestin Assays
2010
A Reporter Gene Assay for High-Throughput Screening of G-Protein-Coupled Receptors Stably or Transiently Expressed in HEK293 EBNA Cells Grown in Suspension Culture
2000
Proteomics: New technologies and clinical applications
2008
Expression of the prostaglandin E2 (PGE2) receptor subtype EP4 and its regulation by PGE2 in osteoblastic cell lines and adult rat bone tissue11M.W. and M.M. contributed equally to this study.
2001
Cloning and expression of three isoforms of the human EP3 prostanoid receptor
1994
5‐lipoxygenase‐activating protein is an arachidonate binding protein
1993
Key Structural Features of Prostaglandin E2and Prostanoid Analogs Involved in Binding and Activation of the Human EP1Prostanoid Receptor
2001
Characterization of the recombinant human prostanoid DP receptor and identification of L‐644,698, a novel selective DP agonist
1998
Characterization of the cloned guinea pig leukotriene B4 receptor: comparison to its human orthologue
1999
Differential Localization of Glutathione‐S‐Transferase Yp and Yb Subunits in Oligodendrocytes and Astrocytes of Rat Brain
1989
The utilization of recombinant prostanoid receptors to determine the affinities and selectivities of prostaglandins and related analogs
2000
Molecular Cloning and Characterization of the Human Prostanoid DP Receptor
1995
5‐Lipoxygenase‐activating protein stimulates the utilization of arachidonic acid by 5‐lipoxygenase
1993
Molecular cloning and characterization of the four rat prostaglandin E2 prostanoid receptor subtypes
1997
Detection of Adenylate Cyclase-Coupled Receptors in Xenopus Oocytes by Coexpression with Cystic Fibrosis Transmembrane Conductance Regulator
1995
Protein-Coding and MicroRNA Biomarkers of Recurrence of Prostate Cancer Following Radical Prostatectomy
2011
Human prostanoid receptors: cloning and characterization.
1995
Coexpression of full-length gamma-aminobutyric acid(B) (GABA(B)) receptors with truncated receptors and metabotropic glutamate receptor 4 supports the GABA(B) heterodimer as the functional receptor.
2000
Cloning and expression of a cDNA for the human prostanoid FP receptor.
1994
Cloning and expression of a cDNA for the human prostanoid IP receptor.
1994
Cloning and expression of a cDNA for the human prostaglandin E receptor EP1 subtype.
1993
Evaluation of the role of conserved His and Met residues among lipoxygenases by site-directed mutagenesis of recombinant human 5-lipoxygenase.
1991
Disease-Free Survival According to Degree of HER2 Amplification for Patients Treated With Adjuvant Chemotherapy With or Without 1 Year of Trastuzumab: The HERA Trial
2009
Nuclear localization of prostaglandin E 2 receptors
1998