Citation Impact
Citing Papers
Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma
2003 StandoutNobel
A Recombinant Immunotoxin against the Tumor-Associated Antigen Mesothelin Reengineered for High Activity, Low Off-Target Toxicity, and Reduced Antigenicity
2012
Immunotherapy of chronic hepatitis C virus infection with antibodies against programmed cell death-1 (PD-1)
2013 StandoutNobel
ICOS co-stimulatory receptor is essential for T-cell activation and function
2001 StandoutNatureNobel
Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4
1992
Identification of a receptor for BLyS demonstrates a crucial role in humoral immunity
2000
T cell co-stimulation and in vivo tolerance
1993
Mannose 6-Phosphate Receptor Targeting and its Applications in Human Diseases
2007
Differentiation of trophoblast endocrine cells
1996
B70 antigen is a second ligand for CTLA-4 and CD28
1993 Nature
CD28-B7 interactions in T-cell activation
1994 StandoutNobel
Developmental regulation of MHC class II transport in mouse dendritic cells
1997 StandoutNatureNobel
Absence of B7-dependent responses in CD28-deficient mice
1994
Enhanced expression of B7-1, B7-2, and intercellular adhesion molecule 1 in sinusoidal endothelial cells by warm ischemia/reperfusion injury in rat liver
2001 StandoutNobel
Signals and signs for lymphocyte responses
1994
Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
2015 StandoutNobel
The emerging role of CTLA4 as a cell-extrinsic regulator of T cell responses
2011
Regulation of receptor-mediated endocytosis by phorbol esters
1991
Selective recycling of the mannose 6-phosphate/IGF-II receptor to the trans Golgi network in vitro
1988
CTLA-4 can function as a negative regulator of T cell activation
1994 Standout
The immunologic basis for the treatment of psoriasis with new biologic agents
2002
Treatment of Murine Lupus with CTLA4Ig
1994 Science
The Role of the CD28 Receptor During T Cell Responses to Antigen
1993
The Role of CTLA‐4 in the Regulation and Initiation of T‐Cell Responses
1996 StandoutNobel
Betaglycan presents ligand to the TGFβ signaling receptor
1993
Interleukin‐12 and B7.1 co‐stimulation cooperate in the induction of effective antitumor immunity and therapy of established tumors
1996
Induction of Peripheral T Cell Tolerance In Vivo Requires CTLA-4 Engagement
1997
Distinct Cellular Mechanisms Underlie Anti-CTLA-4 and Anti-PD-1 Checkpoint Blockade
2017 StandoutNobel
Human B7-1 (CD80) and B7-2 (CD86) bind with similar avidities but distinct kinetics to CD28 and CTLA-4 receptors
1994
Dendritic cells and the control of immunity
1998 StandoutNatureNobel
Regulation of transcription and cell identity by POU domain proteins
1991 StandoutNobel
The Complexities of T‐Cell Co‐stimulation: CD28 and Beyond
1996
Lysosome-targeting chimaeras for degradation of extracellular proteins
2020 StandoutNatureNobel
Collagen-induced arthritis in the BB rat. Prevention of disease by treatment with CTLA-4-Ig.
1995
The expanding B7 superfamily: Increasing complexity in costimulatory signals regulating T cell function
2001
The B7 and CD28 receptor families
1994
Pituitary cell phenotypes involve cell-specific Pit-1 mRNA translation and synergistic interactions with other classes of transcription factors.
1990
Lymphoproliferation in CTLA-4–Deficient Mice Is Mediated by Costimulation-Dependent Activation of CD4 + T Cells
1997 StandoutNobel
Mechanisms of intracellular protein transport
1994 StandoutNatureNobel
New perspectives of C1328-137-mediated T cell costimulation
1995
Clathrin, Adaptors, and Sorting
1990
A coat subunit of Golgi-derived non-clathrin-coated vesicles with homology to the clathrin-coated vesicle coat protein β-adaptin
1991 StandoutNatureNobel
The CD28-Related Molecule ICOS Is Required for Effective T Cell–Dependent Immune Responses
2000
In vivoblockade of CTLA-4 enhances the priming of responsive T cells but fails to prevent the induction of tumor antigen-specific tolerance
1999 StandoutNobel
Thymocyte development is normal in CTLA-4-deficient mice
1997 StandoutNobel
Manipulation of T cell costimulatory and inhibitory signals for immunotherapy of prostate cancer
1997 StandoutNobel
Biochemical evidence that the type II insulin-like growth factor receptor is identical to the cation-independent mannose 6-phosphate receptor.
1988
The Cytoplasmic Domain of CD28 Is both Necessary and Sufficient for Costimulation of Interleukin-2 Secretion and Association with Phosphatidylinositol 3′-Kinase
1994
Therapy of murine tumors with tumor peptide-pulsed dendritic cells: dependence on T cells, B7 costimulation, and T helper cell 1-associated cytokines.
1996
The cytoplasmic domain of CD28 is both necessary and sufficient for costimulation of interleukin-2 secretion and association with phosphatidylinositol 3'-kinase.
1994
Serotonin-Mediated Endocytosis of apCAM: an Early Step of Learning-Related Synaptic Growth in Aplysia
1992 StandoutScienceNobel
Localization of the signal for rapid internalization of the bovine cation-independent mannose 6-phosphate/insulin-like growth factor-II receptor to amino acids 24-29 of the cytoplasmic tail.
1991
CTLA-4 blockade synergizes with tumor-derived granulocyte– macrophage colony-stimulating factor for treatment of an experimental mammary carcinoma
1998 StandoutNobel
Expression and functional significance of an additional ligand for CTLA-4.
1993
Regulation of dendritic cell numbers and maturation by lipopolysaccharide in vivo.
1996
Interaction of the Cytoplasmic Tail of CTLA-4 (CD152) with a Clathrin-Associated Protein Is Negatively Regulated by Tyrosine Phosphorylation
1997
Interleukin-10 induces a long-term antigen-specific anergic state in human CD4+ T cells.
1996
B7x: A widely expressed B7 family member that inhibits T cell activation
2003 StandoutNobel
Integrated NY-ESO-1 antibody and CD8+T-cell responses correlate with clinical benefit in advanced melanoma patients treated with ipilimumab
2011 StandoutNobel
Interaction of CTLA-4 with AP50, a clathrin-coated pit adaptor protein
1997 StandoutNobel
CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation.
1995 StandoutNobel
CD28/B7 SYSTEM OF T CELL COSTIMULATION
1996 Standout
A Critical Role for B7/CD28 Costimulation in Experimental Autoimmune Encephalomyelitis: A Comparative Study Using Costimulatory Molecule-Deficient Mice and Monoclonal Antibody Blockade
2000
A highly phosphorylated subpopulation of insulin-like growth factor II/mannose 6-phosphate receptors is concentrated in a clathrin-enriched plasma membrane fraction.
1988
Coat Proteins and Vesicle Budding
1996 StandoutScienceNobel
Inhibitory Receptors on Lymphocytes: Insights from Infections
2012
Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated cancer patients
2008 StandoutNobel
Primary Structure of a Putative Receptor for a Ligand of the Insulin Family
1989
Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability
2009 StandoutNobel
Induction of autoimmune disease by deletion of CTLA-4 in mice in adulthood
2016 StandoutNobel
Multiple endocytic pathways of G protein-coupled receptors delineated by GIT1 sensitivity
2000 StandoutNobel
Increase in TNF-α and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a)
2005 StandoutNobel
Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients
2003 StandoutNobel
GTP-binding Ypt1 protein and Ca2+ function independently in a cell-free protein transport reaction.
1990 StandoutNobel
Regulation of the mannose 6-phosphate/IGF II receptor expression at the cell surface by mannose 6-phosphate, insulin like growth factors and epidermal growth factor.
1989 StandoutNobel
Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
2002 StandoutNobel
The Yin and Yang of T Cell Costimulation
1995 StandoutScienceNobel
Uncovering of Functional Alternative CTLA-4 Counter-Receptor in B7-Deficient Mice
1993 Science
The future of immune checkpoint therapy
2015 StandoutScienceNobel
Long-Term Survival of Xenogeneic Pancreatic Islet Grafts Induced by CTLA4lg
1992 StandoutScience
T-Independent Immune Response: New Aspects of B Cell Biology
2000 StandoutScienceNobel
Coexpression and functional cooperation of CTLA-4 and CD28 on activated T lymphocytes.
1992
Protein Sorting by Transport Vesicles
1996 StandoutScienceNobel
Complexities of CD28/B7: CTLA-4 Costimulatory Pathways in Autoimmunity and Transplantation
2001
B cell function in mice transgenic for mCTLA4-H gamma 1: lack of germinal centers correlated with poor affinity maturation and class switching despite normal priming of CD4+ T cells.
1994
daf-2 , an Insulin Receptor-Like Gene That Regulates Longevity and Diapause in Caenorhabditis elegans
1997 StandoutScienceNobel
Specificity of binding of clathrin adaptors to signals on the mannose-6-phosphate/insulin-like growth factor II receptor.
1989
Treg-expressed CTLA-4 depletes CD80/CD86 by trogocytosis, releasing free PD-L1 on antigen-presenting cells
2021 StandoutNobel
CTLA-4 blockade enhances polyfunctional NY-ESO-1 specific T cell responses in metastatic melanoma patients with clinical benefit
2008 StandoutNobel
Structure of the Receptor for Insulin-Like Growth Factor II: The Puzzle Amplified
1988 Science
Single dose of anti–CTLA-4 enhances CD8 + T-cell memory formation, function, and maintenance
2010 StandoutNobel
Foxp3+ Treg cells in humoral immunity
2013 StandoutNobel
CTLA-4: a negative regulator of autoimmune disease.
1996
Enhancement of Antitumor Immunity by CTLA-4 Blockade
1996 StandoutScienceNobel
B70/B7-2 is identical to CD86 and is the major functional ligand for CD28 expressed on human dendritic cells.
1994
HIV-1-infected monocyte-derived dendritic cells do not undergo maturation but can elicit IL-10 production and T cell regulation
2004 StandoutNobel
A distinct subpopulation of CD25−T-follicular regulatory cells localizes in the germinal centers
2017 StandoutNobel
Antibody to Langerin/CD207 localizes large numbers of CD8α + dendritic cells to the marginal zone of mouse spleen
2009 StandoutNobel
Proliferin Induces Endothelial Cell Chemotaxis through a G Protein-Coupled, Mitogen-Activated Protein Kinase-Dependent Pathway*
1997
Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade
2002 StandoutNobel
Differential T Cell Costimulatory Requirements in CD28-Deficient Mice
1993 Science
ß-Arrestin 2 Mediates Endocytosis of Type III TGF-ß Receptor and Down-Regulation of Its Signaling
2003 StandoutScienceNobel
Recombinant immunotoxin for cancer treatment with low immunogenicity by identification and silencing of human T-cell epitopes
2014 StandoutNobel
Differential control of human Treg and effector T cells in tumor immunity by Fc-engineered anti–CTLA-4 antibody
2018 StandoutNobel
Elimination of residual metastatic prostate cancer after surgery and adjunctive cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) blockade immunotherapy
1999 StandoutNobel
Works of Mark A. Tepper being referenced
Evidence for Only Oneβ-Luteinizing Hormone and Noβ-Chorionic Gonadotropin Gene in the Rat*
1984
Specific binding of Fyn and phosphatidylinositol 3‐kinase to the B cell surface glycoprotein CD19 through their src homology 2 domains
1995
Immunosuppression in Vivo by a Soluble Form of the CTLA-4 T Cell Activation Molecule
1992 Science
A Single Receptor Binds Both Insulin-Like Growth Factor II and Mannose-6-Phosphate
1988 Science
Tolerance induction by soluble CTLA4 in a mouse skin transplant model.
1994
Prevention of immunotoxin-mediated vascular leak syndrome in rats with retention of antitumor activity.
1994