Citation Impact
Citing Papers
Complement and microglia mediate early synapse loss in Alzheimer mouse models
2016 StandoutScience
Neurotoxic protein expression reveals connections between the circadian clock and mating behavior in Drosophila
2006 StandoutNobel
Multidimensional traction force microscopy reveals out-of-plane rotational moments about focal adhesions
2012 StandoutNobel
In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter
2010 StandoutNobel
Actin retrograde flow actively aligns and orients ligand-engaged integrins in focal adhesions
2017 StandoutNobel
α-Synuclein Promotes SNARE-Complex Assembly in Vivo and in Vitro
2010 StandoutScienceNobel
A drug-controllable tag for visualizing newly synthesized proteins in cells and whole animals
2008 StandoutNobel
Strategy for Dual-Analyte Luciferin Imaging: In Vivo Bioluminescence Detection of Hydrogen Peroxide and Caspase Activity in a Murine Model of Acute Inflammation
2013 StandoutNobel
4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1
2007 StandoutNobel
A Genomewide Search for Ribozymes Reveals an HDV-Like Sequence in the Human CPEB3 Gene
2006 StandoutScienceNobel
Proteomic identification of nitrated proteins in Alzheimer's disease brain
2003
A new function for the fragile X mental retardation protein in regulation of PSD-95 mRNA stability
2007
Kissing complex RNAs mediate interaction between the Fragile-X mental retardation protein KH2 domain and brain polyribosomes
2005
Global Analysis of Protein Damage by the Lipid Electrophile 4-Hydroxy-2-nonenal
2008
Drosophila FMRP regulates microtubule network formation and axonal transport of mitochondria
2010
A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins
2002
Dysregulated Metabotropic Glutamate Receptor-Dependent Translation of AMPA Receptor and Postsynaptic Density-95 mRNAs at Synapses in a Mouse Model of Fragile X Syndrome
2007
Ionotropic Glutamate Receptors & CNS Disorders
2008
The DNA-damage response in human biology and disease
2009 StandoutNature
Nitric oxide induces tau hyperphosphorylation via glycogen synthase kinase‐3β activation
2005
Inflammation and Alzheimer's disease
2000 Standout
Inflammatory processes in Alzheimer's disease
2007
A neuroscientist's guide to lipidomics
2007
The physiology and pathophysiology of nitric oxide in the brain
2005
β-Catenin regulates expression of cyclin D1 in colon carcinoma cells
1999 StandoutNature
Tyrosine nitration of a synaptic protein synaptophysin contributes to amyloid β-peptide-induced cholinergic dysfunction
2003
MicroRNAs
2004 Standout
Quantitative assessment of tyrosine nitration of manganese superoxide dismutase in angiotensin II-infused rat kidney
2003
Aberrant expression of nitric oxide synthase III in Alzheimer’s disease: relevance to cerebral vasculopathy and neurodegeneration
2000
Oxidative Stress and Neurodegeneration
2005
Neuronal and glial calcium signaling in Alzheimer’s disease
2003
Channel opening and gating mechanism in AMPA-subtype glutamate receptors
2017 StandoutNatureNobel
Peroxynitrite induces GADD34, 45, and 153 VIA p38 MAPK in human neuroblastoma SH-SY5Y cells
2001
Free radicals, metals and antioxidants in oxidative stress-induced cancer
2006 Standout
The metallobiology of Alzheimer's disease
2003
Inducible nitric oxide synthase expression in human cerebral infarcts
1999
Oxidative stress, dysfunctional glucose metabolism and Alzheimer disease
2019 Standout
Amyloid β‐Peptide(1‐42) Contributes to the Oxidative Stress and Neurodegeneration Found in Alzheimer Disease Brain
2004
Mitochondrial dysfunction, apoptotic cell death, and Alzheimer’s disease
2003
TRP channels and lipids: from Drosophila to mammalian physiology
2006
Transient Receptor Potential A1 Is a Sensory Receptor for Multiple Products of Oxidative Stress
2008
The Drosophila Circadian Network Is a Seasonal Timer
2007 StandoutNobel
Role of nitric oxide in Parkinson's disease
2005
In Situ Oxidative Catalysis by Neurofibrillary Tangles and Senile Plaques in Alzheimer’s Disease
2000
Regulation of Xanthine Oxidase by Nitric Oxide and Peroxynitrite
2000
Tyrosine nitration: Localisation, quantification, consequences for protein function and signal transduction
2001
TRIBE: Hijacking an RNA-Editing Enzyme to Identify Cell-Specific Targets of RNA-Binding Proteins
2016 StandoutNobel
Proteomics in Alzheimer's disease: insights into potential mechanisms of neurodegeneration
2003
β‐Site APP cleaving enzyme up‐regulation induced by 4‐hydroxynonenal is mediated by stress‐activated protein kinases pathways
2005
Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway
2004
Intervention strategies to inhibit protein carbonylation by lipoxidation‐derived reactive carbonyls
2006
Evidence that the β-Amyloid Plaques of Alzheimer's Disease Represent the Redox-silencing and Entombment of Aβ by Zinc
2000
Structure of the Alzheimer's Disease Amyloid Precursor Protein Copper Binding Domain
2003
Dynamic molecular processes mediate cellular mechanotransduction
2011 Nature
Nitric Oxide and Peroxynitrite in Health and Disease
2007 Standout
Phosphatidylinositol 3-Kinase Is a Target for Protein Tyrosine Nitration
1998
NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice
2012 StandoutNature
Biological aspects of reactive nitrogen species
1999
Structural and functional features of central nervous system lymphatic vessels
2015 StandoutNature
Oxidative stress mechanisms and potential therapeutics in Alzheimer disease
2004
β-Amyloid-Mediated Inhibition of NMDA Receptor-Dependent Long-Term Potentiation Induction Involves Activation of Microglia and Stimulation of Inducible Nitric Oxide Synthase and Superoxide
2004
Novel Recurrent Genetic Imbalances in Human Hepatocellular Carcinoma Cell Lines Identified by Comparative Genomic Hybridization
1999
Review: Alzheimer's Amyloid β-Peptide-Associated Free Radical Oxidative Stress and Neurotoxicity
2000
Mitochondrial fragmentation in neurodegeneration
2008
Adventiously-bound redox active iron and copper are at the center of oxidative damage in Alzheimer disease
2003
Evolution of neuronal changes in the course of Alzheimer’s disease
1998
Neurodegenerative disorders: the role of peroxynitrite
1999
Copper reduction by copper binding proteins and its relation to neurodegenerative diseases
2003
A Cell-Penetrating Scorpion Toxin Enables Mode-Specific Modulation of TRPA1 and Pain
2019 StandoutNobel
Biological inorganic and bioinorganic chemistry of neurodegeneration based on prion and Alzheimer diseases
2004
Aberrant expression of NOS isoforms in Alzheimer’s disease is structurally related to nitrotyrosine formation
2002
Redox-active iron mediates amyloid-β toxicity
2001
Chapter 19 Role of endogenous nitric oxide and peroxynitrite formation in the survival and death of motor neurons in culture
1998
TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action
2016 StandoutNatureNobel
The Role of Iron and Copper in the Aetiology of Neurodegenerative Disorders
2002
Processing of primary microRNAs by the Microprocessor complex
2004 StandoutNature
Oxidants, oxidative stress and the biology of ageing
2000 StandoutNature
Cellular and Molecular Mechanisms of Pain
2009 StandoutNobel
Nitration and inactivation of cytochrome P450BM‐3 by peroxynitrite
2000
Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids
2018 StandoutNobel
Repair of peroxynitrite damage to tubulin by the thioredoxin reductase system
2004
Fragile X-related protein and VIG associate with the RNA interference machinery
2002
Regulation of local mRNA translation
2004
Inflammatory Neurodegeneration Mediated by Nitric Oxide, Glutamate, and Mitochondria
2003
Alzheimer's Disease
2010 Standout
Peroxynitrite Inactivates Tryptophan Hydroxylase via Sulfhydryl Oxidation
1999
Contribution of redox-active iron and copper to oxidative damage in Alzheimer disease
2004
[39] Immunohistochemical methods to detect nitrotyrosine
1999
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
2006 StandoutNature
Dityrosine Cross-linking Promotes Formation of Stable α-Synuclein Polymers
2000
Tamoxifen inhibits nitrotyrosine formation after reversible middle cerebral artery occlusion in the rat
2001
Relevance of protein nitration in brain injury: a key pathophysiological mechanism in neurodegenerative, autoimmune, or inflammatory CNS diseases and stroke
2003
Nitration of Tyrosine 10 Critically Enhances Amyloid β Aggregation and Plaque Formation
2011
Molecular biology of glutamate receptors in the central nervous system and their role in excitotoxicity, oxidative stress and aging
1998
Quantitative reactivity profiling predicts functional cysteines in proteomes
2010 StandoutNatureNobel
Nitric oxide, mitochondria and neurological disease
1999
β‐Amyloid inhibits integrated mitochondrial respiration
and key enzyme activities
2001
A coding-independent function of gene and pseudogene mRNAs regulates tumour biology
2010 StandoutNature
Coupled oscillators control morning and evening locomotor behaviour of Drosophila
2004 StandoutNatureNobel
Peroxynitrite Induces Tyrosine Nitration and Modulates Tyrosine Phosphorylation of Synaptic Proteins
1999
Mechanisms of gene silencing by double-stranded RNA
2004 StandoutNature
Peroxynitrite affects exocytosis and SNARE complex formation and induces tyrosine nitration of synaptic proteins
2002
Alterations of 3-nitrotyrosine concentration in the cerebrospinal fluid during aging and in patients with Alzheimer's disease
1999
Pathways towards and away from Alzheimer's disease
2004 StandoutNature
The evolution of Olig genes and their roles in myelination
2008
Genetics and molecular biology of rhythms in Drosophila and other insects
2003 StandoutNobel
Evidence of oxidative damage in Alzheimer's disease brain: central role for amyloid β-peptide
2001
Dynamics of Nitrotyrosine Formation and Decay in Rat Brain during Focal Ischemia-Reperfusion
1999
Peroxynitrite-Induced Tyrosine Nitration and Inhibition of Protein Kinase C
2001
Astroglial Nitration after Postnatal Excitotoxic Damage: Correlation with Nitric Oxide Sources, Cytoskeletal, Apoptotic and Antioxidant Proteins
2005
Glutathione Depletion in a Midbrain-Derived Immortalized Dopaminergic Cell Line Results in Limited Tyrosine Nitration of Mitochondrial Complex I Subunits: Implications for Parkinson's Disease
2005
The Role of Oxidative Stress in the Dysregulation of Gene Expression and Protein Metabolism in Neurodegenerative Disease
2006
Oxidative Damage Linked to Neurodegeneration by Selective α-Synuclein Nitration in Synucleinopathy Lesions
2000 Science
Nitric oxide-induced mitochondrial dysfunction: implications for neurodegeneration
2003
Nitric Oxide and Superoxide Contribute to Motor Neuron Apoptosis Induced by Trophic Factor Deprivation
1998
Biological Tyrosine Nitration: A Pathophysiological Function of Nitric Oxide and Reactive Oxygen Species
1998
Increased plaque burden in brains of APP mutant MnSOD heterozygous knockout mice
2004
N-formylation of lysine in histone proteins as a secondary modification arising from oxidative DNA damage
2006
Lysosomal activity regulatesCaenorhabditis elegansmitochondrial dynamics through vitamin B12 metabolism
2020 StandoutNobel
INFLAMMATION AND ALZHEIMERS DISEASE
2000
The Alzheimer's Disease Amyloid Precursor Protein Modulates Copper-Induced Toxicity and Oxidative Stress in Primary Neuronal Cultures
1999
Uric acid, a natural scavenger of peroxynitrite, in experimental allergic encephalomyelitis and multiple sclerosis
1998
The Aβ Peptide of Alzheimer's Disease Directly Produces Hydrogen Peroxide through Metal Ion Reduction
1999
Peroxynitrite induces Alzheimer‐like tau modifications and accumulation in rat brain and its underlying mechanisms
2006
Copper Homeostasis and Neurodegenerative Disorders (Alzheimer's, Prion, and Parkinson's Diseases and Amyotrophic Lateral Sclerosis)
2006 Standout
Iron accumulation in Alzheimer disease is a source of redox-generated free radicals
1997
Astrocytic nitric oxide triggers tau hyperphosphorylation in hippocampal neurons.
2005
Oxidative Stress Induces Intracellular Accumulation of Amyloid β-Protein (Aβ) in Human Neuroblastoma Cells
2000
Mice carrying a human GLUD2 gene recapitulate aspects of human transcriptome and metabolome development
2016 StandoutNobel
Inactivation of tyrosine hydroxylase by nitration following exposure to peroxynitrite and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)
1998
Mitochondrial Manganese Superoxide Dismutase Prevents Neural Apoptosis and Reduces Ischemic Brain Injury: Suppression of Peroxynitrite Production, Lipid Peroxidation, and Mitochondrial Dysfunction
1998
Breathtaking TRP Channels: TRPA1 and TRPV1 in Airway Chemosensation and Reflex Control
2008
Synaptic alterations in CA1 in mild Alzheimer disease and mild cognitive impairment
2007
Somatic mutations of the β-catenin gene are frequent in mouse and human hepatocellular carcinomas
1998
Piezo1, a mechanically activated ion channel, is required for vascular development in mice
2014 StandoutNobel
Regulation of apoptosis by the circadian clock through NF-κB signaling
2011 StandoutNobel
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
Copper induces cell death by targeting lipoylated TCA cycle proteins
2022 StandoutScience
The relationship between oxidative/nitrative stress and pathological inclusions in Alzheimer’s and Parkinson’s diseases1,2 11Guest Editors: Mark A. Smith and George Perry 22This article is part of a series of reviews on “Causes and Consequences of Oxidative Stress in Alzheimer’s Disease.” The full list of papers may be found on the homepage of the journal.
2002
Increased F 2 ‐isoprostanes in Alzheimer's disease: evidence for enhanced lipid peroxidation in vivo
1998
nNOS Expression in Reactive Astrocytes Correlates with Increased Cell Death Related DNA Damage in the Hippocampus and Entorhinal Cortex in Alzheimer's Disease
2000
Analysis of peptides and proteins containing nitrotyrosine by matrix-assisted laser desorption/ionization mass spectrometry
2001
Enzymatic aminoacylation of tRNA with unnatural amino acids
2006 StandoutNobel
Transcriptomes of germinal zones of human and mouse fetal neocortex suggest a role of extracellular matrix in progenitor self-renewal
2012 StandoutNobel
Endogenously Nitrated Proteins in Mouse Brain: Links to Neurodegenerative Disease
2006
EUK-134, a synthetic superoxide dismutase and catalase mimetic, prevents oxidative stress and attenuates kainate-induced neuropathology
1999
Identification of many microRNAs that copurify with polyribosomes in mammalian neurons
2003 StandoutNobel
Free Radicals in the Physiological Control of Cell Function
2002 Standout
Mutations in the DJ-1 Gene Associated with Autosomal Recessive Early-Onset Parkinsonism
2003 StandoutScience
Palaeoproteomic evidence identifies archaic hominins associated with the Châtelperronian at the Grotte du Renne
2016 StandoutNobel
Electrochemical Analysis of Protein Nitrotyrosine and Dityrosine in the Alzheimer Brain Indicates Region-Specific Accumulation
1998
Peroxynitrite modulates tyrosine phosphorylation and phosphoinositide signalling in human neuroblastoma SH-SY5Y cells: attenuated effects in human 1321N1 astrocytoma cells
1998
Oxidative stress in neurodegeneration: cause or consequence?
2004 Standout
Peroxynitrite decomposition catalysts: Therapeutics for peroxynitrite-mediated pathology
1998
Works of Mark A. Smith being referenced
Oxidative Damage Is the Earliest Event in Alzheimer Disease
2001 Standout
Rolling blackout, a newly identified PIP2-DAG pathway lipase required for Drosophila phototransduction
2004
Drosophila Fragile X-Related Gene Regulates the MAP1B Homolog Futsch to Control Synaptic Structure and Function
2001
4‐Hydroxynonenal‐Derived Advanced Lipid Peroxidation End Products Are Increased in Alzheimer's Disease
1997
Extracellular neurofibrillary tangles reflect neuronal loss and provide further evidence of extensive protein cross-linking in Alzheimer disease
1995
Is increased redox-active iron in Alzheimer disease a failure of the copper-binding protein ceruloplasmin?
1999
Dimethylargininase, a nitric oxide regulatory protein, in Alzheimer disease
1998
A Zyxin-Mediated Mechanism for Actin Stress Fiber Maintenance and Repair
2010
Dorsoventral Patterning in Hemichordates: Insights into Early Chordate Evolution
2006
Low frequency of p53 mutations observed in a diverse collection of primary hepatocellular carcinomas.
1992
4-Oxo-2-nonenal Is Both More Neurotoxic and More Protein Reactive than 4-Hydroxy-2-nonenal
2005
Widespread Peroxynitrite-Mediated Damage in Alzheimer’s Disease
1997
Loss of heterozygosity suggests tumor suppressor gene responsible for primary hepatocellular carcinoma.
1989