Citation Impact
Citing Papers
Loading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitro
2003 StandoutNobel
Early-Onset Lymphoma and Extensive Embryonic Apoptosis in Two Domain-Specific Fen1 Mice Mutants
2008
Saccharomyces cerevisiae MutLα Is a Mismatch Repair Endonuclease
2007 StandoutNobel
hMSH3 and hMSH6 interact with PCNA and colocalize with it to replication foci
2001
Hallmarks of Cancer: The Next Generation
2011 Standout
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
2008 StandoutNature
Base-excision repair of oxidative DNA damage
2007 StandoutNature
XPG: Its Products and Biological Roles
2008
Critical DNA damage recognition functions of XPC‐hHR23B and XPA‐RPA in nucleotide excision repair
2003
Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase
2005 StandoutNature
MGMT: Key node in the battle against genotoxicity, carcinogenicity and apoptosis induced by alkylating agents
2007
Mechanism Whereby Proliferating Cell Nuclear Antigen Stimulates Flap Endonuclease 1
2000
PCNA binding proteins
1999
XPG protein has a structure-specific endonuclease activity
1995
Conserved Residues of Human XPG Protein Important for Nuclease Activity and Function in Nucleotide Excision Repair
1999
Human DNA Repair Excision Nuclease
1995 StandoutNobel
DNA repair investigations using siRNA
2003
DNA excision repair pathways
1997 StandoutNobel
Mismatch repair and nucleotide excision repair proteins cooperate in the recognition of DNA interstrand crosslinks
2009 StandoutNobel
Regulation of DNA replication and repair proteins through interaction with the front side of proliferating cell nuclear antigen
1998
Reaction Mechanism of Human DNA Repair Excision Nuclease
1996 StandoutNobel
When Checkpoints Fail
1997 StandoutNobel
Endonucleolytic Function of MutLα in Human Mismatch Repair
2006 StandoutNobel
Regulation of nucleotide excision repair activity by transcriptional and post-transcriptional control of the XPA protein
2010 StandoutNobel
Database of mouse strains carrying targeted mutations in genes affecting cellular responses to DNA damage. Version 4
2000
Complementation of the DNA-repair defect in a CHO mutant by human DNA that lacks highly abundant repetitive sequences
1988
Transcription factor b (TFIIH) is required during nucleotide-excision repair in yeast
1994 StandoutNatureNobel
Lethality in PARP-1/Ku80 double mutant mice reveals physiological synergy during early embryogenesis
2003
Transfection of the cloned human excision repair gene ERCC-1 to UV-sensitive CHO mutants only corrects the repair defect in complementation group-2 mutants
1988
Open complex formation around a lesion during nucleotide excision repair provides a structure for cleavage by human XPG protein
1997
Base Excision Repair of Oxidative DNA Damage Activated by XPG Protein
1999 StandoutNobel
Essential Amino Acids for Substrate Binding and Catalysis of Human Flap Endonuclease 1
1996
Synthetic lethality between mutation in Atm and DNA-PK cs during murine embryogenesis
2001
RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO
2002 StandoutNature
Nucleotide Excision Repair in Mammalian Cells
1997
Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family
2011 StandoutNobel
Functional Interaction of Proliferating Cell Nuclear Antigen with MSH2-MSH6 and MSH2-MSH3 Complexes
2000
Defective repair of cisplatin-induced DNA damage caused by reduced XPA protein in testicular germ cell tumours
1999
Electron Crystal Structure of the Transcription Factor and DNA Repair Complex, Core TFIIH
2000 StandoutNobel
Deoxyribonucleoside triphosphate levels: A critical factor in the maintenance of genetic stability
1994
Dynamics of β and Proliferating Cell Nuclear Antigen Sliding Clamps in Traversing DNA Secondary Structure
2000
XPG endonuclease makes the 3′ incision in human DNA nucleotide excision repair
1994 Nature
Poly(ADP-ribose): novel functions for an old molecule
2006 Standout
Genome maintenance mechanisms for preventing cancer
2001 StandoutNature
Somatic hypermutation at A·T pairs: polymerase error versus dUTP incorporation
2005
Transcriptome Engineering with RNA-Targeting Type VI-D CRISPR Effectors
2018
Structure of the DNA Repair and Replication Endonuclease and Exonuclease FEN-1
1998
DDB Accumulates at DNA Damage Sites Immediately after UV Irradiation and Directly Stimulates Nucleotide Excision Repair
2002 StandoutNobel
Properties of and Substrate Determinants for the Exonuclease Activity of Human Apurinic Endonuclease Ape1
2003
The major human abasic endonuclease: formation, consequences and repair of abasic lesions in DNA
2001
DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis
2020 StandoutNatureNobel
Exploring complex networks
2001 StandoutNature
Functional interaction between PARP-1 and PARP-2 in chromosome stability and embryonic development in mouse
2003
Rescue of Xrcc1 knockout mouse embryo lethality by transgene-complementation
2003
Domain swapping between FEN-1 and XPG defines regions in XPG that mediate nucleotide excision repair activity and substrate specificity
2007
Isolation of the functional human excision repair gene ERCC5 by intercosmid recombination
1990
Post-replicative base excision repair in replication foci
1999
Analysis of Interactions Between Mismatch Repair Initiation Factors and the Replication Processivity Factor PCNA
2005
Molecular mechanism of nucleotide excision repair
1999
HRad17 Colocalizes with NHP2L1 in the Nucleolus and Redistributes after UV Irradiation
1999
The major human AP endonuclease (Ape1) is involved in the nucleotide incision repair pathway
2004
PCNA function in the activation and strand direction of MutLα endonuclease in mismatch repair
2010 StandoutNobel
Beta-agonist- and prostaglandin E1-induced translocation of the beta-adrenergic receptor kinase: evidence that the kinase may act on multiple adenylate cyclase-coupled receptors.
1986 StandoutNobel
p53-Mediated Regulation of Proliferating Cell Nuclear Antigen Expression in Cells Exposed to Ionizing Radiation
1999
Postnatal Growth Failure, Short Life Span, and Early Onset of Cellular Senescence and Subsequent Immortalization in Mice Lacking the Xeroderma Pigmentosum Group G Gene
1999
Purification and characterization of human DNA damage checkpoint Rad complexes
2001 StandoutNobel
Functional domains within FEN-1 and RAD2 define a family of structure-specific endonucleases: implications for nucleotide excision repair.
1994
Reconstitution of a human ATR-mediated checkpoint response to damaged DNA
2007 StandoutNobel
Molecular Interaction Map of the Mammalian Cell Cycle Control and DNA Repair Systems
1999 Nobel
The puzzle of PCNA's many partners
2000
Requirement for human AP endonuclease 1 for repair of 3′-blocking damage at DNA single-strand breaks induced by reactive oxygen species
2000
Quality Control by DNA Repair
1999 StandoutScienceNobel
Mechanisms of DNA Excision Repair
1994 StandoutScienceNobel
Early Embryonic Lethality in PARP-1 AtmDouble-Mutant Mice Suggests a Functional Synergy in Cell Proliferation during Development
2001
Domainal evolution of a prokaryotic DNA repair protein and its relationship to active-transport proteins
1986 StandoutNatureNobel
Revertants of a trans-dominant S49 mouse lymphoma mutant that affects expression of cAMP-dependent protein kinase
1983
Initiation of methyl-directed mismatch repair.
1992 StandoutNobel
Online Nanoflow RP−RP-MS Reveals Dynamics of Multicomponent Ku Complex in Response to DNA Damage
2010
Heterozygosity for the mouse Apex gene results in phenotypes associated with oxidative stress.
2001
Processing of Damaged DNA Ends for Double-Strand Break Repair in Mammalian Cells
2012
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
Structural and functional conservation of the human homolog of the Schizosaccharomyces pombe rad2 gene, which is required for chromosome segregation and recovery from DNA damage.
1994
Functional complementation of xeroderma pigmentosum complementation group E by replication protein A in an in vitro system.
1996 StandoutNobel
ERCC4 (XPF) Encodes a Human Nucleotide Excision Repair Protein with Eukaryotic Recombination Homologs
1996 StandoutNobel
Repair and Genetic Consequences of Endogenous DNA Base Damage in Mammalian Cells
2004 StandoutNobel
DNA nucleotide excision repair-dependent signaling to checkpoint activation
2006
THE DNA REPLICATION FORK IN EUKARYOTIC CELLS
1998
The Saccharomyces cerevisiae RAD6 Group Is Composed of an Error-Prone and Two Error-Free Postreplication Repair Pathways
2000
Requirement for human AP endonuclease 1 for repair of 3′-blocking damage at DNA single-strand breaks induced by reactive oxygen species
2000
Assembly, subunit composition, and footprint of human DNA repair excision nuclease
1998 StandoutNobel
Action of DNA Repair Endonuclease ERCC1/XPF in Living Cells
1999 Science
Differential regulation of S-region hypermutation and class-switch recombination by noncanonical functions of uracil DNA glycosylase
2014 StandoutNobel
In vivo studies of repair of 2-aminopurine in Escherichia coli
1988
Hepatitis C Virus IRES RNA-Induced Changes in the Conformation of the 40 S Ribosomal Subunit
2001 StandoutScienceNobel
Molecular characterization of the human excision repair gene : cDNA cloning and amino acid homology with the yeast DNA repair gene
1986
Saccharomyces cerevisiae pol30 (Proliferating Cell Nuclear Antigen) Mutations Impair Replication Fidelity and Mismatch Repair
1999
APE1- and APE2-dependent DNA breaks in immunoglobulin class switch recombination
2007
Significance analysis of microarrays applied to the ionizing radiation response
2001 Standout
Extrahelical (CAG)/(CTG) triplet repeat elements support proliferating cell nuclear antigen loading and MutLα endonuclease activation
2013 StandoutNobel
Isolation of active recombinant XPG protein, a human DNA repair endonuclease.
1994
Human DNA Repair Genes
2001 StandoutScienceNobel
Translocation of a UV-damaged DNA binding protein into a tight association with chromatin after treatment of mammalian cells with UV light
1997
Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligase
2010 StandoutNobel
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
APE1 is dispensable for S-region cleavage but required for its repair in class switch recombination
2014 StandoutNobel
The human Rad9–Rad1–Hus1 checkpoint complex stimulates flap endonuclease 1
2004 StandoutNobel
Removal of oxygen free-radical-induced 5′,8-purine cyclodeoxynucleosides from DNA by the nucleotide excision-repair pathway in human cells
2000 StandoutNobel
Molecular Mechanisms of Mammalian DNA Repair and the DNA Damage Checkpoints
2004 StandoutNobel
Molecular cloning of the human nucleotide-excision-repair gene ERCC4.
1994 StandoutNobel
Apurinic/Apyrimidinic Endonuclease 1 Is the Essential Nuclease during Immunoglobulin Class Switch Recombination
2013
Structure and Function of DNA Photolyase and Cryptochrome Blue-Light Photoreceptors
2003 StandoutNobel
Works of Mark A. MacInnes being referenced
Two essential but distinct functions of the mammalian abasic endonuclease
2005
Molecular cloning and structural analysis of the functional mouse genomic XPG gene
1996
A murine AP-endonuclease gene-targeted deficiency with post-implantation embryonic progression and ionizing radiation sensitivity
1998
Heritable genetic alterations in a xeroderma pigmentosum group G/Cockayne syndrome pedigree
1997
Multiple nuclear localization signals in XPG nuclease
1996
The Dynamic Alterations of H2AX Complex during DNA Repair Detected by a Proteomic Approach Reveal the Critical Roles of Ca2+/Calmodulin in the Ionizing Radiation-induced Cell Cycle Arrest
2006
The DNA Repair Endonuclease XPG Binds to Proliferating Cell Nuclear Antigen (PCNA) and Shares Sequence Elements with the PCNA-binding Regions of FEN-1 and Cyclin-dependent Kinase Inhibitor p21
1997
Quantitative forward-mutation specificity of mono-functional alkylating agents, ICR-191, and aflatoxin B1 in mouse lymphoma cells
1982
Mechanism of 2-aminopurine mutagenesis in mouse T-lymphosarcoma cells.
1982
Human ERCC5 cDNA-cosmid complementation for excision repair and bipartite amino acid domains conserved with RAD proteins of Saccharomyces cerevisiae and Schizosaccharomyces pombe.
1993
DNA-Mediated Cotransfer of Excision Repair Capacity and Drug Resistance into Chinese Hamster Ovary Mutant Cell Line UV-135
1984
Ultraviolet-induced movement of the human DNA repair protein, Xeroderma pigmentosum type G, in the nucleus.
1996
DNA-mediated cotransfer of excision repair capacity and drug resistance into chinese hamster ovary mutant cell line UV-135.
1984
Human ERCC5 cDNA-Cosmid Complementation for Excision Repair and Bipartite Amino Acid Domains Conserved with RAD Proteins of Saccharomyces cerevisiae and Schizosaccharomyces pombe
1993