Citation Impact
Citing Papers
Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes
2018 StandoutScienceNobel
Microbial Exposure During Early Life Has Persistent Effects on Natural Killer T Cell Function
2012 Science
Maturation-Dependent HIV-1 Surface Protein Redistribution Revealed by Fluorescence Nanoscopy
2012 StandoutScienceNobel
CTLA4 blockade expands FoxP3+ regulatory and activated effector CD4+ T cells in a dose-dependent fashion
2008 StandoutNobel
A Sulfilimine Bond Identified in Collagen IV
2009 StandoutScienceNobel
Mouse models of acute and chronic hepacivirus infection
2017 StandoutScienceNobel
The microbiota regulates type 2 immunity through RORγt + T cells
2015 StandoutScienceNobel
Vα24-JαQ-Independent, CD1d-Restricted Recognition of α-Galactosylceramide by Human CD4+ and CD8αβ+ T Lymphocytes
2002
Loss of T Cell and B Cell Quiescence Precedes the Onset of Microbial Flora-Dependent Wasting Disease and Intestinal Inflammation in Gimap5-Deficient Mice
2010 StandoutNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
Detection and activation of human Vα24+ natural killer T cells using α-galactosyl ceramide-pulsed dendritic cells
2003 StandoutNobel
Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections
2005 StandoutNatureNobel
TCR zeta chain lacking exon 7 in two patients with systemic lupus erythematosus
1998
Regulation of antitumour immunity by CD1d-restricted NKT cells
2004
Ulcerative Colitis
2011 Standout
Nucleotide signalling during inflammation
2014 StandoutNature
T cell exhaustion
2011 Standout
Unravelling the pathogenesis of inflammatory bowel disease
2007 StandoutNature
Suppression of inflammation in ulcerative colitis by interferon-β-1a is accompanied by inhibition of IL-13 production
2010
The natural killer T-cell ligand α-galactosylceramide prevents autoimmune diabetes in non-obese diabetic mice
2001
Vaccines Against Drug Abuse
2011
Regulatory T Cells
2000 StandoutNobel
Identification of the residues in human CD4 critical for the binding of HIV
1989 StandoutNobel
Regulatory T Cells in Cancer
2010
Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1
2007 StandoutNatureNobel
A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans
1996 StandoutNatureNobel
Quantitation and phenotypic analysis of natural killer T cells in primary biliary cirrhosis using a human CD1d tetramer
2002
Regulatory T Cells and Immune Tolerance
2008 StandoutNobel
Immunization with α-galactosylceramide polarizes CD1-reactive NK T cells towards Th2 cytokine synthesis
1999
Activation of natural killer T cells by α-galactosylceramide treatment prevents the onset and recurrence of autoimmune Type 1 diabetes
2001
Animal models of autoimmunity and their relevance to human diseases
2000 StandoutNobel
NKT cells: what's in a name?
2004
Inflammatory bowel disease: cause and immunobiology
2007 Standout
Inflammatory Bowel Disease
2009 Standout
CD1-restricted T-cell responses and microbial infection
2000 Nature
Activation-Induced Cytidine Deaminase Links Between Inflammation and the Development of Colitis-Associated Colorectal Cancers
2008 StandoutNobel
Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice
2003 StandoutNatureNobel
Ulcerative colitis
2012 Standout
Oxazolone Colitis, a Th2 Colitis Model Resembling Ulcerative Colitis, Is Mediated by IL-13-Producing NK-T Cells
2002
Expression and functional characterization of FOXP3+CD4+ regulatory T cells in ulcerative colitis
2006
Pathogenesis of chronic viral hepatitis: differential roles of T cells and NK cells
2013
Crystal structure of an HIV-binding recombinant fragment of human CD4
1990 StandoutNatureNobel
Mechanisms of Disease: pathogenesis of Crohn's disease and ulcerative colitis
2006
CD1d on antigen-transporting APC and splenic marginal zone B cells promotes NKT cell-dependent tolerance
2002
Ulcerative colitis
2016 Standout
Delineation of a CD1d-restricted antigen presentation pathway associated with human and mouse intestinal epithelial cells
2003
Regulatory Natural Killer T Cells Protect against Spontaneous and Recurrent Type 1 Diabetes
2002
Goodpasture Autoantibodies Unmask Cryptic Epitopes by Selectively Dissociating Autoantigen Complexes Lacking Structural Reinforcement
2005
CD4+CD25high regulatory T cells in human autoimmune diabetes
2005
Single amino-acid changes in HIV envelope affect viral tropism and receptor binding
1989 StandoutNatureNobel
Going both ways: Immune regulation via CD1d-dependent NKT cells
2004
Critical role of Vα14+ natural killer T cells in the innate phase of host protection against Streptococcus pneumoniae infection
2003
Protein Disulfide Isomerase Acts as a Redox-Dependent Chaperone to Unfold Cholera Toxin
2001
Computational design of ligand-binding proteins with high affinity and selectivity
2013 StandoutNatureNobel
Mechanism of CD1d-restricted natural killer T cell activation during microbial infection
2003
Proinflammatory Cytokines in the Pathogenesis of Inflammatory Bowel Diseases
2011
soluble form of CD4 (T4) protein inhibits AIDS virus infection
1988 StandoutNatureNobel
CD1-dependent dendritic cell instruction
2002
Epithelial apoptosis is a prominent feature of the epithelial barrier disturbance in intestinal inflammation: effect of pro-inflammatory interleukin-13 on epithelial cell function
2008
Increased susceptibility to colitis and colorectal tumors in mice lacking core 3–derived O-glycans
2007
Autoreactive T Cells in Healthy Individuals
2004
Inhibition of glycolipid shedding rescues recognition of a CD1+T cell lymphoma by natural killer T (NKT) cells
2002
Detection of self-reactive CD8 + T cells with an anergic phenotype in healthy individuals
2014 StandoutScienceNobel
Flying Under the Radar: The Immunobiology of Hepatitis C
2006 StandoutNobel
Der1, a novel protein specifically required for endoplasmic reticulum degradation in yeast.
1996
The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain
1986 StandoutNobel
Genome organization and transactivation of the human immunodeficiency virus type 2
1987 StandoutNatureNobel
Loss of CD4 membrane expression and CD4 mRNA during acute human immunodeficiency virus replication.
1988 StandoutNobel
The isolation and nucleotide sequence of a cDNA encoding the T cell surface protein T4: a new member of the immunoglobulin gene family
1985 StandoutNobel
Human Immunodeficiency Viruses
1986 StandoutScienceNobel
The Structure and Function of P55PIK Reveal a New Regulatory Subunit for Phosphatidylinositol 3-Kinase
1995
A History of HIV Discovery
2002 StandoutScienceNobel
Cutting Edge: Cross-Talk Between Cells of the Innate Immune System: NKT Cells Rapidly Activate NK Cells
1999
Regulatory T Cells in Autoimmmunity
2000
Diabetes Prone BB Rats are Severely Deficient in Natural Killer T Cells
1999
Sequential production of interferon-γ by NK1.1+ T cells and natural killer cells is essential for the antimetastatic effect of α-galactosylceramide
2002
Dendritic Cell Maturation Overrules H-2d–Mediated Natural Killer T (Nkt) Cell Inhibition
2001
Dynamics of Pathogenic and Suppressor T Cells in Autoimmune Diabetes Development
2003
Impaired Long-Term Potentiation, Spatial Learning, and Hippocampal Development in fyn Mutant Mice
1992 StandoutScienceNobel
p27x-III and p21x-III, proteins encoded by the pX sequence of human T-cell leukemia virus type I.
1985
Distinct Functional Lineages of Human Vα24 Natural Killer T Cells
2002
Activation of Natural Killer T Cells by α-Galactosylceramide Rapidly Induces the Full Maturation of Dendritic Cells In Vivo and Thereby Acts as an Adjuvant for Combined CD4 and CD8 T Cell Immunity to a Coadministered Protein
2003 StandoutNobel
Activation of Natural Killer T Cells Potentiates or Prevents Experimental Autoimmune Encephalomyelitis
2001
T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV
1984 StandoutNatureNobel
Assembly of ER-associated protein degradation in vitro: dependence on cytosol, calnexin, and ATP.
1996
Interleukin-13 Is the Key Effector Th2 Cytokine in Ulcerative Colitis That Affects Epithelial Tight Junctions, Apoptosis, and Cell Restitution
2005
The Immunology of Mucosal Models of Inflammation
2002
The chronology of AIDS research
1987 StandoutNatureNobel
The Biology of Interleukin-2
2007
Tracking the Response of Natural Killer T Cells to a Glycolipid Antigen Using Cd1d Tetramers
2000
Going both ways: Immune regulation via CD1d-dependent NKT cells
2004
CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells
2006 Standout
Inflammatory Bowel Disease
2010 Standout
Regulation of antitumour immunity by CD1d-restricted NKT cells
2004
A Reversible Defect in Natural Killer T Cell Function Characterizes the Progression of Premalignant to Malignant Multiple Myeloma
2003
A phase I study of the natural killer T-cell ligand alpha-galactosylceramide (KRN7000) in patients with solid tumors.
2002
Emerging Challenges in Regulatory T Cell Function and Biology
2007 StandoutScienceNobel
Natural Killer T Cell Activation Protects Mice Against Experimental Autoimmune Encephalomyelitis
2001
Viruses in Human Cancers
1991 StandoutScienceNobel
In Vivo Identification of Glycolipid Antigen–Specific T Cells Using Fluorescent Cd1d Tetramers
1999
The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus
1984 StandoutNature
Human NKT Cells Mediate Antitumor Cytotoxicity Directly by Recognizing Target Cell CD1d with Bound Ligand or Indirectly by Producing IL-2 to Activate NK Cells
2001
THE NOD MOUSE: A Model of Immune Dysregulation
2004
Functional deficiencies of granulocyte-macrophage colony stimulating factor and interleukin-3 contribute to insulitis and destruction of β cells
2007 StandoutNobel
Pseudotypes of human T-cell leukemia virus types 1 and 2: neutralization by patients' sera.
1984
CD25+ CD4+ T Cells, Expanded with Dendritic Cells Presenting a Single Autoantigenic Peptide, Suppress Autoimmune Diabetes
2004 StandoutNobel
CD1.1 Expression by Mouse Antigen-Presenting Cells and Marginal Zone B Cells
1998
Therapeutic activation of Vα24+Vβ11+ NKT cells in human subjects results in highly coordinated secondary activation of acquired and innate immunity
2003
CD4+ T Cells Prevent Spontaneous Experimental Autoimmune Encephalomyelitis in Anti–Myelin Basic Protein T Cell Receptor Transgenic Mice
1998 Nobel
V. Polarized compartmentalization of antigen processing and Toll-like receptor signaling in intestinal epithelial cells
2002
CD1: Antigen Presentation and T Cell Function
2004
Activation of tyrosine kinase p60fyn following T cell antigen receptor cross-linking.
1992
A Critical Role for Natural Killer T Cells in Immunosurveillance of Methylcholanthrene-induced Sarcomas
2002
Sustained expansion of NKT cells and antigen-specific T cells after injection of α-galactosyl-ceramide loaded mature dendritic cells in cancer patients
2005 StandoutNobel
Infection of HTLV-III/LAV in HTLV-I-Carrying Cells MT-2 and MT-4 and Application in a Plaque Assay
1985 Science
CD4+CD25+ T-cell development is regulated by at least 2 distinct mechanisms
2002
Functionally Distinct Subsets of CD1d-restricted Natural Killer T Cells Revealed by CD1d Tetramer Staining
2002
Cd1-Restricted Nk T Cells Protect Nonobese Diabetic Mice from Developing Diabetes
2001
CD4−CD8αα Subset of CD1d-Restricted NKT Cells Controls T Cell Expansion
2004
Molecular cloning and polymorphism of the human immune deficiency virus type 2
1986 StandoutNatureNobel
Innate NKT lymphocytes confer superior adaptive immunity via tumor-capturing dendritic cells
2005 StandoutNobel
Characterization of Foxp3+CD4+CD25+ and IL-10-Secreting CD4+CD25+ T Cells during Cure of Colitis
2006 StandoutNobel
Protein Translocation Across Biological Membranes
2005 StandoutScienceNobel
Cross-presentation of Disialoganglioside GD3 to Natural Killer T Cells
2003
Continuous Activation of Autoreactive CD4+ CD25+ Regulatory T Cells in the Steady State
2003
Tumor necrosis factor-α regulation of CD4+C25+T cell levels in NOD mice
2002
Systemic NKT cell deficiency in NOD mice is not detected in peripheral blood: implications for human studies
2004
Works of Mark A. Exley being referenced
CD1d structure and regulation on human thymocytes, peripheral blood T cells,B cells and monocytes
2000
CD1d-dependent macrophage-mediated clearance of Pseudomonas aeruginosa from lung
2002
Extreme Th1 bias of invariant Vα24JαQ T cells in type 1 diabetes
1998 Nature
Nonclassical CD1d-restricted NK T cells that produce IL-13 characterize an atypical Th2 response in ulcerative colitis
2004
Efficacy of a therapeutic cocaine vaccine in rodent models
1996
Multiple immuno-regulatory defects in type-1 diabetes
2002
CD1d function is regulated by microsomal triglyceride transfer protein
2004
Biochemical Characterization of CD1d Expression in the Absence of β2-Microglobulin
1999
Natural killer T cell dysfunction in CD39-null mice protects against concanavalin A–induced hepatitis
2008
Disseminated Varicella Infection Due to the Vaccine Strain of Varicella‐Zoster Virus, in a Patient with a Novel Deficiency in Natural Killer T Cells
2003
Activation of natural killer T cells by α-galactosylceramide in the presence of CD1d provides protection against colitis in mice
2000
CD161 (NKR-P1A) Costimulation of CD1d-dependent Activation of Human T Cells Expressing Invariant Vα24JαQ T Cell Receptor α Chains
1998
Cd1-Reactive Natural Killer T Cells Are Required for Development of Systemic Tolerance through an Immune-Privileged Site
1999
Nonclassical CD1d-restricted NK T cells that produce IL-13 characterize an atypical Th2 response in ulcerative colitis
2004
Hepatitis C Virus (HCV)-Specific CD8+Cells Produce Transforming Growth Factor β That Can Suppress HCV-Specific T-Cell Responses
2007
Activation of CD1d-restricted T cells protects NOD mice from developing diabetes by regulating dendritic cell subsets
2001
NK T Cell-Derived IL-10 Is Essential for the Differentiation of Antigen-Specific T Regulatory Cells in Systemic Tolerance
2001
Hepatic CD1d Expression in Hepatitis C Virus Infection and Recognition by Resident Proinflammatory CD1d-Reactive T Cells
2004
Effects of the Administration of High-Dose Interleukin-2 on Immunoregulatory Cell Subsets in Patients with Advanced Melanoma and Renal Cell Cancer
2007
Cutting Edge: A Major Fraction of Human Bone Marrow Lymphocytes Are Th2-Like CD1d-Reactive T Cells That Can Suppress Mixed Lymphocyte Responses
2001
Regulation of selective protein degradation in the endoplasmic reticulum by redox potential.
1993
Human immunodeficiency virus infection of monocytic and T-lymphocytic cells: Receptor modulation and differentiation induced by phorbol ester
1987
Loss of IFN-γ Production by Invariant NK T Cells in Advanced Cancer
2001
Cutting Edge: Compartmentalization of Th1-Like Noninvariant CD1d-Reactive T Cells in Hepatitis C Virus-Infected Liver
2002
Involvement of CD1 in Peripheral Deletion of T Lymphocytes Is Independent of NK T Cells
2001
Structure, assembly and intracellular transport of the T cell receptor for antigen.
1991
Multiple immuno-regulatory defects in type-1 diabetes
2002
Role of CD1d in Coxsackievirus B3-Induced Myocarditis
2003
Multiple immuno-regulatory defects in type-1 diabetes
2002
Productive Infection and Cell-Free Transmission of Human T-Cell Leukemia Virus in a Nonlymphoid Cell Line
1983 Science
Human CD1d Functions as a Transplantation Antigen and a Restriction Element in Mice
2001
CD1d-reactive T-cell activation leads to amelioration of disease caused by diabetogenic encephalomyocarditis virus
2001
Association of phosphatidylinositol 3-kinase with a specific sequence of the T cell receptor zeta chain is dependent on T cell activation.
1994
CD1d ligation on human monocytes directly signals rapid NF-κB activation and production of bioactive IL-12
2005
Requirements for CD1d Recognition by Human Invariant Vα24+ CD4−CD8− T Cells
1997
CD1d-restricted T cells regulate dendritic cell function and antitumor immunity in a granulocyte–macrophage colony-stimulating factor-dependent fashion
2003